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Abortive intussusceptive angiogenesis causes multi-cavernous vascular malformations. Elife. 2021 05 20; 10.
Li W, Tran V, Shaked I, Xue B, Moore T, Lightle R, Kleinfeld D, Awad IA, Ginsberg MH. PMID: 34013885.
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AnimalsCells
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Endothelial struts enable the generation of large lumenized blood vessels de novo. Nat Cell Biol. 2021 04; 23(4):322-329.
Weijts B, Shaked I, Ginsberg M, Kleinfeld D, Robin C, Traver D. PMID: 33837285.
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HumansCells
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Transcription factor Nr4a1 couples sympathetic and inflammatory cues in CNS-recruited macrophages to limit neuroinflammation. Nat Immunol. 2015 Dec; 16(12):1228-34.
Shaked I, Hanna RN, Shaked H, Chodaczek G, Nowyhed HN, Tweet G, Tacke R, Basat AB, Mikulski Z, Togher S, Miller J, Blatchley A, Salek-Ardakani S, Darvas M, Kaikkonen MU, Thomas GD, Lai-Wing-Sun S, Rezk A, Bar-Or A, Glass CK, Bandukwala H, Hedrick CC, Shaked I, Hanna RN, Shaked H, Chodaczek G, Nowyhed HN, Tweet G, Tacke R, Basat AB, Mikulski Z, Togher S, Miller J, Blatchley A, Salek-Ardakani S, Darvas M, Kaikkonen MU, Thomas GD, Lai-Wing-Sun S, Rezk A, Bar-Or A, Glass CK, Bandukwala H, Hedrick CC. PMID: 26523867; PMCID: PMC4833087.
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PubMed Mentions:
43 Fields:
Translation:
HumansAnimalsCells
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Patrolling monocytes control tumor metastasis to the lung. Science. 2015 Nov 20; 350(6263):985-90.
Hanna RN, Cekic C, Sag D, Tacke R, Thomas GD, Nowyhed H, Herrley E, Rasquinha N, McArdle S, Wu R, Peluso E, Metzger D, Ichinose H, Shaked I, Chodaczek G, Biswas SK, Hedrick CC, Hanna RN, Cekic C, Sag D, Tacke R, Thomas GD, Nowyhed H, Herrley E, Rasquinha N, McArdle S, Wu R, Peluso E, Metzger D, Ichinose H, Shaked I, Chodaczek G, Biswas SK, Hedrick CC. PMID: 26494174; PMCID: PMC4869713.
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PubMed Mentions:
143 Fields:
Translation:
AnimalsCells
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SAMP1/YitFc mice develop ileitis via loss of CCL21 and defects in dendritic cell migration. Gastroenterology. 2015 Apr; 148(4):783-793.e5.
Mikulski Z, Johnson R, Shaked I, Kim G, Nowyhed H, Goodman W, Chodaczek G, Pizarro TT, Cominelli F, Ley K, Mikulski Z, Johnson R, Shaked I, Kim G, Nowyhed H, Goodman W, Chodaczek G, Pizarro TT, Cominelli F, Ley K. PMID: 25620669; PMCID: PMC4375031.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Macrophage inflammatory markers are associated with subclinical carotid artery disease in women with human immunodeficiency virus or hepatitis C virus infection. Arterioscler Thromb Vasc Biol. 2014 May; 34(5):1085-92.
Shaked I, Hanna DB, Gleißner C, Marsh B, Plants J, Tracy D, Anastos K, Cohen M, Golub ET, Karim R, Lazar J, Prasad V, Tien PC, Young MA, Landay AL, Kaplan RC, Ley K, Shaked I, Hanna DB, Gleißner C, Marsh B, Plants J, Tracy D, Anastos K, Cohen M, Golub ET, Karim R, Lazar J, Prasad V, Tien PC, Young MA, Landay AL, Kaplan RC, Ley K. PMID: 24651679; PMCID: PMC4067091.
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PubMed Mentions:
34 Fields:
Translation:
HumansCells
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The autoimmunity-associated gene PTPN22 potentiates toll-like receptor-driven, type 1 interferon-dependent immunity. Immunity. 2013 Jul 25; 39(1):111-22.
Wang Y, Shaked I, Stanford SM, Zhou W, Curtsinger JM, Mikulski Z, Shaheen ZR, Cheng G, Sawatzke K, Campbell AM, Auger JL, Bilgic H, Shoyama FM, Schmeling DO, Balfour HH, Hasegawa K, Chan AC, Corbett JA, Binstadt BA, Mescher MF, Ley K, Bottini N, Peterson EJ, Wang Y, Shaked I, Stanford SM, Zhou W, Curtsinger JM, Mikulski Z, Shaheen ZR, Cheng G, Sawatzke K, Campbell AM, Auger JL, Bilgic H, Shoyama FM, Schmeling DO, Balfour HH, Hasegawa K, Chan AC, Corbett JA, Binstadt BA, Mescher MF, Ley K, Bottini N, Peterson EJ. PMID: 23871208; PMCID: PMC3830738.
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PubMed Mentions:
93 Fields:
Translation:
HumansAnimalsCells
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Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses. Cell. 2012 Sep 28; 151(1):138-52.
Spann NJ, Garmire LX, McDonald JG, Myers DS, Milne SB, Shibata N, Reichart D, Fox JN, Shaked I, Heudobler D, Raetz CR, Wang EW, Kelly SL, Sullards MC, Murphy RC, Merrill AH, Brown HA, Dennis EA, Li AC, Ley K, Tsimikas S, Fahy E, Subramaniam S, Quehenberger O, Russell DW, Glass CK, Spann NJ, Garmire LX, McDonald JG, Myers DS, Milne SB, Shibata N, Reichart D, Fox JN, Shaked I, Heudobler D, Raetz CR, Wang EW, Kelly SL, Sullards MC, Murphy RC, Merrill AH, Brown HA, Dennis EA, Li AC, Ley K, Tsimikas S, Fahy E, Subramaniam S, Quehenberger O, Russell DW, Glass CK. PMID: 23021221; PMCID: PMC3464914.
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PubMed Mentions:
199 Fields:
Translation:
AnimalsCells
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Protective role for myeloid specific KLF2 in atherosclerosis. Circ Res. 2012 May 11; 110(10):1266.
Shaked I, Ley K, Shaked I, Ley K. PMID: 22581916.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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NR4A1 (Nur77) deletion polarizes macrophages toward an inflammatory phenotype and increases atherosclerosis. Circ Res. 2012 Feb 03; 110(3):416-27.
Hanna RN, Shaked I, Hubbeling HG, Punt JA, Wu R, Herrley E, Zaugg C, Pei H, Geissmann F, Ley K, Hedrick CC, Hanna RN, Shaked I, Hubbeling HG, Punt JA, Wu R, Herrley E, Zaugg C, Pei H, Geissmann F, Ley K, Hedrick CC. PMID: 22194622; PMCID: PMC3309661.
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PubMed Mentions:
164 Fields:
Translation:
HumansAnimalsCells
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CXC chemokine ligand 4 induces a unique transcriptome in monocyte-derived macrophages. J Immunol. 2010 May 01; 184(9):4810-8.
Gleissner CA, Shaked I, Little KM, Ley K, Gleissner CA, Shaked I, Little KM, Ley K. PMID: 20335529; PMCID: PMC3418140.
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PubMed Mentions:
85 Fields:
Translation:
HumansCells
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MicroRNA-132 potentiates cholinergic anti-inflammatory signaling by targeting acetylcholinesterase. Immunity. 2009 Dec 18; 31(6):965-73.
Shaked I, Meerson A, Wolf Y, Avni R, Greenberg D, Gilboa-Geffen A, Soreq H, Shaked I, Meerson A, Wolf Y, Avni R, Greenberg D, Gilboa-Geffen A, Soreq H. PMID: 20005135.
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PubMed Mentions:
188 Fields:
Translation:
HumansAnimalsCells
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CXCL4 downregulates the atheroprotective hemoglobin receptor CD163 in human macrophages. Circ Res. 2010 Jan 08; 106(1):203-11.
Gleissner CA, Shaked I, Erbel C, Böckler D, Katus HA, Ley K, Gleissner CA, Shaked I, Erbel C, Böckler D, Katus HA, Ley K. PMID: 19910578; PMCID: PMC2876722.
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PubMed Mentions:
45 Fields:
Translation:
HumansAnimalsCells
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Stress-induced alternative splicing modulations in brain and periphery: acetylcholinesterase as a case study. Ann N Y Acad Sci. 2008 Dec; 1148:269-81.
Shaked I, Zimmerman G, Soreq H, Shaked I, Zimmerman G, Soreq H. PMID: 19120119.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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The thymic theme of acetylcholinesterase splice variants in myasthenia gravis. Blood. 2007 May 15; 109(10):4383-91.
Gilboa-Geffen A, Lacoste PP, Soreq L, Cizeron-Clairac G, Le Panse R, Truffault F, Shaked I, Soreq H, Berrih-Aknin S, Gilboa-Geffen A, Lacoste PP, Soreq L, Cizeron-Clairac G, Le Panse R, Truffault F, Shaked I, Soreq H, Berrih-Aknin S. PMID: 17272501.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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MicroRNA modulation of megakaryoblast fate involves cholinergic signaling. Leuk Res. 2006 May; 30(5):583-95.
Guimaraes-Sternberg C, Meerson A, Shaked I, Soreq H, Guimaraes-Sternberg C, Meerson A, Shaked I, Soreq H. PMID: 16249029.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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T-cell-based vaccination for morphological and functional neuroprotection in a rat model of chronically elevated intraocular pressure. J Mol Med (Berl). 2005 Nov; 83(11):904-16.
Bakalash S, Ben-Shlomo G, Shlomo GB, Aloni E, Shaked I, Wheeler L, Ofri R, Schwartz M, Bakalash S, Ben-Shlomo G, Shlomo GB, Aloni E, Shaked I, Wheeler L, Ofri R, Schwartz M. PMID: 16096740.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCellsPHPublic Health
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Early activation of microglia as antigen-presenting cells correlates with T cell-mediated protection and repair of the injured central nervous system. J Neuroimmunol. 2004 Jan; 146(1-2):84-93.
Shaked I, Porat Z, Gersner R, Kipnis J, Schwartz M, Shaked I, Porat Z, Gersner R, Kipnis J, Schwartz M. PMID: 14698850.
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PubMed Mentions:
43 Fields:
Translation:
AnimalsCells
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Protective autoimmunity against the enemy within: fighting glutamate toxicity. Trends Neurosci. 2003 Jun; 26(6):297-302.
Schwartz M, Shaked I, Fisher J, Mizrahi T, Schori H, Schwartz M, Shaked I, Fisher J, Mizrahi T, Schori H. PMID: 12798598.
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PubMed Mentions:
33 Fields:
Translation:
AnimalsCells
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Autoimmunity as a special case of immunity: removing threats from within. Trends Mol Med. 2003 Mar; 9(3):88-93.
Nevo U, Kipnis J, Golding I, Shaked I, Neumann A, Akselrod S, Schwartz M, Nevo U, Kipnis J, Golding I, Shaked I, Neumann A, Akselrod S, Schwartz M. PMID: 12657429.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Neuroprotective autoimmunity: naturally occurring CD4+CD25+ regulatory T cells suppress the ability to withstand injury to the central nervous system. Proc Natl Acad Sci U S A. 2002 Nov 26; 99(24):15620-5.
Kipnis J, Mizrahi T, Hauben E, Shaked I, Shevach E, Schwartz M, Kipnis J, Mizrahi T, Hauben E, Shaked I, Shevach E, Schwartz M. PMID: 12429857; PMCID: PMC137766.
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PubMed Mentions:
79 Fields:
Translation:
AnimalsCellsPHPublic Health
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Glutamine synthetase enhances the clearance of extracellular glutamate by the neural retina. J Neurochem. 2002 Nov; 83(3):574-80.
Shaked I, Ben-Dror I, Vardimon L, Shaked I, Ben-Dror I, Vardimon L. PMID: 12390519.
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PubMed Mentions:
21 Fields:
Translation:
AnimalsCells