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Iftach Shaked

Title(s)Assistant Project Scientist, Physics
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Transcription factor Nr4a1 couples sympathetic and inflammatory cues in CNS-recruited macrophages to limit neuroinflammation. Nat Immunol. 2015 Dec; 16(12):1228-34. Shaked I, Hanna RN, Shaked H, Chodaczek G, Nowyhed HN, Tweet G, Tacke R, Basat AB, Mikulski Z, Togher S, Miller J, Blatchley A, Salek-Ardakani S, Darvas M, Kaikkonen MU, Thomas GD, Lai-Wing-Sun S, Rezk A, Bar-Or A, Glass CK, Bandukwala H, Hedrick CC. PMID: 26523867.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    2. Patrolling monocytes control tumor metastasis to the lung. Science. 2015 Nov 20; 350(6263):985-90. Hanna RN, Cekic C, Sag D, Tacke R, Thomas GD, Nowyhed H, Herrley E, Rasquinha N, McArdle S, Wu R, Peluso E, Metzger D, Ichinose H, Shaked I, Chodaczek G, Biswas SK, Hedrick CC. PMID: 26494174.
      View in: PubMed   Mentions: 91     Fields:    Translation:AnimalsCells
    3. SAMP1/YitFc mice develop ileitis via loss of CCL21 and defects in dendritic cell migration. Gastroenterology. 2015 Apr; 148(4):783-793.e5. Mikulski Z, Johnson R, Shaked I, Kim G, Nowyhed H, Goodman W, Chodaczek G, Pizarro TT, Cominelli F, Ley K. PMID: 25620669.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    4. Macrophage inflammatory markers are associated with subclinical carotid artery disease in women with human immunodeficiency virus or hepatitis C virus infection. Arterioscler Thromb Vasc Biol. 2014 May; 34(5):1085-92. Shaked I, Hanna DB, Gleißner C, Marsh B, Plants J, Tracy D, Anastos K, Cohen M, Golub ET, Karim R, Lazar J, Prasad V, Tien PC, Young MA, Landay AL, Kaplan RC, Ley K. PMID: 24651679.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    5. The autoimmunity-associated gene PTPN22 potentiates toll-like receptor-driven, type 1 interferon-dependent immunity. Immunity. 2013 Jul 25; 39(1):111-22. Wang Y, Shaked I, Stanford SM, Zhou W, Curtsinger JM, Mikulski Z, Shaheen ZR, Cheng G, Sawatzke K, Campbell AM, Auger JL, Bilgic H, Shoyama FM, Schmeling DO, Balfour HH, Hasegawa K, Chan AC, Corbett JA, Binstadt BA, Mescher MF, Ley K, Bottini N, Peterson EJ. PMID: 23871208.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansAnimalsCells
    6. Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses. Cell. 2012 Sep 28; 151(1):138-52. Spann NJ, Garmire LX, McDonald JG, Myers DS, Milne SB, Shibata N, Reichart D, Fox JN, Shaked I, Heudobler D, Raetz CR, Wang EW, Kelly SL, Sullards MC, Murphy RC, Merrill AH, Brown HA, Dennis EA, Li AC, Ley K, Tsimikas S, Fahy E, Subramaniam S, Quehenberger O, Russell DW, Glass CK. PMID: 23021221.
      View in: PubMed   Mentions: 163     Fields:    Translation:AnimalsCells
    7. Protective role for myeloid specific KLF2 in atherosclerosis. Circ Res. 2012 May 11; 110(10):1266. Shaked I, Ley K. PMID: 22581916.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    8. NR4A1 (Nur77) deletion polarizes macrophages toward an inflammatory phenotype and increases atherosclerosis. Circ Res. 2012 Feb 03; 110(3):416-27. Hanna RN, Shaked I, Hubbeling HG, Punt JA, Wu R, Herrley E, Zaugg C, Pei H, Geissmann F, Ley K, Hedrick CC. PMID: 22194622.
      View in: PubMed   Mentions: 133     Fields:    Translation:HumansAnimalsCells
    9. CXC chemokine ligand 4 induces a unique transcriptome in monocyte-derived macrophages. J Immunol. 2010 May 01; 184(9):4810-8. Gleissner CA, Shaked I, Little KM, Ley K. PMID: 20335529.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansCells
    10. MicroRNA-132 potentiates cholinergic anti-inflammatory signaling by targeting acetylcholinesterase. Immunity. 2009 Dec 18; 31(6):965-73. Shaked I, Meerson A, Wolf Y, Avni R, Greenberg D, Gilboa-Geffen A, Soreq H. PMID: 20005135.
      View in: PubMed   Mentions: 167     Fields:    Translation:HumansAnimalsCells
    11. CXCL4 downregulates the atheroprotective hemoglobin receptor CD163 in human macrophages. Circ Res. 2010 Jan 08; 106(1):203-11. Gleissner CA, Shaked I, Erbel C, Böckler D, Katus HA, Ley K. PMID: 19910578.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    12. Stress-induced alternative splicing modulations in brain and periphery: acetylcholinesterase as a case study. Ann N Y Acad Sci. 2008 Dec; 1148:269-81. Shaked I, Zimmerman G, Soreq H. PMID: 19120119.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    13. The thymic theme of acetylcholinesterase splice variants in myasthenia gravis. Blood. 2007 May 15; 109(10):4383-91. Gilboa-Geffen A, Lacoste PP, Soreq L, Cizeron-Clairac G, Le Panse R, Truffault F, Shaked I, Soreq H, Berrih-Aknin S. PMID: 17272501.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    14. MicroRNA modulation of megakaryoblast fate involves cholinergic signaling. Leuk Res. 2006 May; 30(5):583-95. Guimaraes-Sternberg C, Meerson A, Shaked I, Soreq H. PMID: 16249029.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    15. T-cell-based vaccination for morphological and functional neuroprotection in a rat model of chronically elevated intraocular pressure. J Mol Med (Berl). 2005 Nov; 83(11):904-16. Bakalash S, Ben-Shlomo G, Shlomo GB, Aloni E, Shaked I, Wheeler L, Ofri R, Schwartz M. PMID: 16096740.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCellsPHPublic Health
    16. Early activation of microglia as antigen-presenting cells correlates with T cell-mediated protection and repair of the injured central nervous system. J Neuroimmunol. 2004 Jan; 146(1-2):84-93. Shaked I, Porat Z, Gersner R, Kipnis J, Schwartz M. PMID: 14698850.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    17. Protective autoimmunity against the enemy within: fighting glutamate toxicity. Trends Neurosci. 2003 Jun; 26(6):297-302. Schwartz M, Shaked I, Fisher J, Mizrahi T, Schori H. PMID: 12798598.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    18. Autoimmunity as a special case of immunity: removing threats from within. Trends Mol Med. 2003 Mar; 9(3):88-93. Nevo U, Kipnis J, Golding I, Shaked I, Neumann A, Akselrod S, Schwartz M. PMID: 12657429.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    19. Neuroprotective autoimmunity: naturally occurring CD4+CD25+ regulatory T cells suppress the ability to withstand injury to the central nervous system. Proc Natl Acad Sci U S A. 2002 Nov 26; 99(24):15620-5. Kipnis J, Mizrahi T, Hauben E, Shaked I, Shevach E, Schwartz M. PMID: 12429857.
      View in: PubMed   Mentions: 71     Fields:    Translation:AnimalsCellsPHPublic Health
    20. Glutamine synthetase enhances the clearance of extracellular glutamate by the neural retina. J Neurochem. 2002 Nov; 83(3):574-80. Shaked I, Ben-Dror I, Vardimon L. PMID: 12390519.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells