Hui-chun Irene Su

Title(s)	Professor, Ob/Gyn & Reproductive sciences
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
ORCID	0000-0002-6671-5151
vCard	Download vCard

Biography

education and training

Stanford University, Stanford, CA	AB, BS	06/1997	East Asian Studies, Biology
Albert Einstein College of Medicine, Bronx, NY	MD	06/2001	Medicine
University of Pennsylvania, Philadelphia, PA		06/2005	Residency in Obstetrics and Gynecology
University of Pennsylvania, Philadelphia, PA		06/2008	Fellowship in Reproductive Endocrinology and Infertility
University of Pennsylvania, Philadelphia	MSCE	06/2008	Clinical Epidemiology

awards and honors

Albert Einstein College of Medicine	2000	Alpha Omega Alpha Honor Medical Society
American Society of Reproductive Medicine	2009	Prize Paper Award
San Diego County Medical Society	2013	Top Doctor, Reproductive Endocrinology and Infertility
San Diego County Medical Society	2019	Top Doctor, Reproductive Endocrinology and Infertility

Overview

overview

My team and I conduct patient oriented research on improving reproductive health outcomes in children, adolescents and young adults with cancer. These studies range from qualitative studies to observational cohorts to randomized controlled trials. Our group has characterized the unmet fertility, contraception and pregnancy health informational needs of this population, estimated the trajectory of ovarian function after cancer treatment, developed a multi-dimensional scale to measure the breadth of reproductive concerns after cancer (Reproductive Concerns After Cancer scale), and intervened on reproductive health information needs of breast cancer survivors. We have been successful in studies of geographically dispersed AYA survivors by adapting recruitment, data collection, biosample collection, and ovarian reserve measurement methods to be done remotely from survivors’ home environment. Our work has been supported by the NIH, American Cancer Society and California Breast Cancer Research Program (CBCRP).

keywords

Oncofertility, Cancer survivorship, Infertility, Reproductive aging, Reproductive epidemiology

webpage

	Clinical Profiles
	Reproductive Health After Cancer Research Group

Research

research activities and funding

A pilot cluster randomized controlled trial to evaluate an intervention for tailoring oncofertility care in female cancer survivors
Curebound Foudation Jan 1, 2022 - Dec 31, 2022
Role: PI
Description: Conduct a pilot hybrid type 1 effectiveness-implementation trial of a telehealth intervention for oncofertility care in an adult and a children’s hospital

Evaluating a multi-component oncofertility care intervention for rural young breast cancer survivors
California Breast Cancer Research Program B27BB4247Aug 1, 2021 - Jul 31, 2024
Role: PI
Description: Conduct an interrupted time series trial of a multi-component intervention to deliver women’s health care to rural breast cancer survivors

A pilot study to assess multi-level implementation of state-level fertility preservation insurance benefit mandates for adolescent and young adult cancer survivors
UC San Diego Moores Cancer Center CPC Pilot AwardJul 30, 2020 - Aug 1, 2021
Role: PI
Description: This mixed methods study assesses barriers and facilitators to accessing state-level fertility preservation insurance mandates for fertility preservation for cancer patients, in order to develop implementation strategies.

Creating bridges to women’s health care in young survivors
California Breast Cancer Research Program Community Research CollaborationAug 1, 2019 - Jan 31, 2022
Role: Principal Investigator

Physical activity intervention for young cancer survivors
California Breast Cancer Research Program Community Research CollaborationFeb 1, 2019 - Jul 31, 2020
Role: Co-Investigator

Estimating adverse pregnancy outcomes in female adolescent and young adult cancer survivors
UC San Diego Senate Pilot AwardFeb 1, 2019 - Jan 31, 2020
Role: Principal Investigator

Center for Reproductive Science and Medicine
NIH P50 HD012303-34A1Aug 1, 2016 - Jul 31, 2021
Role: Co-Director, Outreach Core

The Reproductive Window in Young Adult Cancer Survivors
NIH R01HD080952Sep 16, 2014 - May 31, 2019
Role: Principal Investigator

Intervening on reproductive health in young survivors
California Breast Cancer Research Program 20OB-0144Jun 1, 2014 - May 31, 2018
Role: Principal Investigator

Predictors of ovarian failure after chemotherapy in young breast cancer patients
NIH K23HD058799Sep 30, 2009 - Jul 31, 2014
Role: Principal Investigator

Predictors of ovarian insufficiency in young breast cancer patients
American Cancer Society MRSG-08-110-01-CCEJul 1, 2008 - Jun 30, 2013
Role: Principal Investigator

Center for Reproductive Science and Medicine
NIH P50HD012303Dec 1, 1978 - Mar 31, 2021
Role: Co-Director, Outreach Core
Description: Outreach Core for Reproductive and Oncofertility Science Academy - Student and Teacher Academies.

ORNG Applications

Clinical Trials

Featured Publications

Faculty Mentoring

Bibliographic

selected publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

Altmetrics Details

PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Long-term antimüllerian hormone patterns differ by cancer treatment exposures in young breast cancer survivors. Fertil Steril. 2022 05; 117(5):1047-1056. Zhou B, Kwan B, Desai MJ, Nalawade V, Ruddy KJ, Nathan PC, Henk HJ, Murphy JD, Whitcomb BW, Su HI. PMID: 35216831; PMCID: PMC9081208.

View in: PubMed Mentions: 8 Fields:
Rep Reproductive Medicine
Translation:Humans
Assessment of Health Insurance Benefit Mandates for Fertility Preservation Among 11 US States. JAMA Health Forum. 2021; 12(2):e214309. Flores Ortega RE, Yoeun SW, Mesina O, Kaiser BN, McMenamin SB, Su HI. . View Publication.
Association between pregnancy intention and preconception health behaviors. Cancer. 2022 02 01; 128(3):615-623. Din HN, Strong D, Singh-Carlson S, Corliss HL, Hartman SJ, Madanat H, Su HI. PMID: 34634132; PMCID: PMC9546522.

View in: PubMed Mentions: 3 Fields:
Neo Neoplasms
Translation:Humans
Trends in Infertility Care Among Commercially Insured US Women During the COVID-19 Pandemic. JAMA Netw Open. 2021 10 01; 4(10):e2128520. Zhou B, Joudeh A, Desai MJ, Kwan B, Nalawade V, Whitcomb BW, Su HI. PMID: 34613406; PMCID: PMC8495534.

View in: PubMed Mentions: 6 Fields:
Med Medicine (General)
Translation:Humans PHPublic Health
Psychosocial stress and ovarian function in adolescent and young adult cancer survivors. Hum Reprod. 2021 01 25; 36(2):405-414. Kim J, Whitcomb BW, Kwan B, Zava D, Sluss PM, Dietz A, Shliakhtsitsava K, Romero SAD, Natarajan L, Su HI. PMID: 33279981; PMCID: PMC7829546.

View in: PubMed Mentions: 2 Fields:
Rep Reproductive Medicine
Translation:Humans
Beyond Premature Ovarian Insufficiency: Staging Reproductive Aging in Adolescent and Young Adult Cancer Survivors. J Clin Endocrinol Metab. 2021 01 23; 106(2):e1002-e1013. Medica ACO, Whitcomb BW, Shliakhsitsava K, Dietz AC, Pinson K, Lam C, Romero SAD, Sluss P, Sammel MD, Su HI. PMID: 33141175; PMCID: PMC7823232.

View in: PubMed Mentions: 5 Fields:
End Endocrinology Met Metabolism
Translation:Humans
Theory-Guided Development of Fertility Care Implementation Strategies for Adolescent and Young Adult Cancer Survivors. J Adolesc Young Adult Oncol. 2021 10; 10(5):512-520. Dornisch A, Yang EH, Gruspe J, Roesch ER, Aristizabal P, Aarons GA, Helsten T, Takemoto MB, Romero SAD, Kaiser BN, Su HI. PMID: 33470879; PMCID: PMC8666795.

View in: PubMed Mentions: 2 Fields:
Neo Neoplasms Ped Pediatrics
Translation:Humans
Modeling Variation in the Reproductive Lifespan of Female Adolescent and Young Adult Cancer Survivors Using AMH. J Clin Endocrinol Metab. 2020 08 01; 105(8). Su HI, Kwan B, Whitcomb BW, Shliakhsitsava K, Dietz AC, Stark SS, Martinez E, Sluss PM, Sammel MD, Natarajan L. PMID: 32270202; PMCID: PMC7329316.

View in: PubMed Mentions: 19 Fields:
End Endocrinology Met Metabolism
Mental Health Outcomes in Adolescent and Young Adult Female Cancer Survivors of a Sexual Minority. J Adolesc Young Adult Oncol. 2021 04; 10(2):148-155. Desai MJ, Gold RS, Jones CK, Din H, Dietz AC, Shliakhtsitsava K, Martinez ME, Vaida F, Su HI. PMID: 32730111; PMCID: PMC8064930.

View in: PubMed Mentions: 12 Fields:
Neo Neoplasms Ped Pediatrics
Translation:Humans
Reproductive intentions in childless female adolescent and young adult cancer survivors. Fertil Steril. 2020 02; 113(2):392-399. Lam CM, Shliakhtsitsava K, Stark SS, Medica ACO, Pinson KA, Whitcomb BW, Su HI. PMID: 32106992; PMCID: PMC7112460.

View in: PubMed Mentions: 5 Fields:
Rep Reproductive Medicine
Translation:Humans
Efficacy of a web-based women's health survivorship care plan for young breast cancer survivors: a randomized controlled trial. Breast Cancer Res Treat. 2019 Aug; 176(3):579-589. Irene Su H, Stark S, Kwan B, Boles S, Chingos D, Ehren J, Gorman JR, Krychman M, Romero SAD, Mao JJ, Pierce JP, Natarajan L. PMID: 31054032; PMCID: PMC6626763.

View in: PubMed Mentions: 14 Fields:
Neo Neoplasms
Translation:Humans
Ovarian stimulation in young adult cancer survivors on targeted cancer therapies. Fertil Steril. 2016 Nov; 106(6):1475-1478. Su HI, Connell MW, Bazhenova LA. PMID: 27565250; PMCID: PMC5159276.

View in: PubMed Mentions: Fields:
Rep Reproductive Medicine
Translation:Humans
Impact of breast cancer on anti-mullerian hormone levels in young women. Breast Cancer Res Treat. 2013 Jan; 137(2):571-7. Su HI, Flatt SW, Natarajan L, DeMichele A, Steiner AZ. PMID: 23224236; PMCID: PMC3540167.

View in: PubMed Mentions: 15 Fields:
Neo Neoplasms
Translation:Humans
Risks and benefits of menopausal hormone therapy in postmenopausal Chinese women. Menopause. 2012 Aug; 19(8):931-41. Su IH, Chen YC, Hwang WT, Liu Z, Su TP, Chen TJ, Barnhart KT, Yang YX. PMID: 22453198; PMCID: PMC3387327.

View in: PubMed Mentions: 11 Fields:
Gyn Gynecology
Mucosal integrity and inflammatory markers in the female lower genital tract as potential screening tools for vaginal microbicides. Contraception. 2011 Nov; 84(5):525-32. Su HI, Schreiber CA, Fay C, Parry S, Elovitz MA, Zhang J, Shaunik A, Barnhart K. PMID: 22018129; PMCID: PMC3201765.

View in: PubMed Mentions: 3 Fields:
Rep Reproductive Medicine
Antral follicle count provides additive information to hormone measures for determining ovarian function in breast cancer survivors. Fertil Steril. 2011 Apr; 95(5):1857-9. Su HI, Chung K, Sammel MD, Gracia CR, DeMichele A. PMID: 21193192; PMCID: PMC3062716.

View in: PubMed Mentions: 4 Fields:
Rep Reproductive Medicine
Measuring ovarian function in young cancer survivors. Minerva Endocrinol. 2010 Dec; 35(4):259-70. Su HI. PMID: 21178920.

View in: PubMed Mentions: 10 Fields:
End Endocrinology
Translation:Humans
Weight gain is associated with increased risk of hot flashes in breast cancer survivors on aromatase inhibitors. Breast Cancer Res Treat. 2010 Nov; 124(1):205-11. Su HI, Sammel MD, Springer E, Freeman EW, DeMichele A, Mao JJ. PMID: 20182796; PMCID: PMC3670946.

View in: PubMed Mentions: 25 Fields:
Neo Neoplasms
Translation:Humans
Antimullerian hormone and inhibin B are hormone measures of ovarian function in late reproductive-aged breast cancer survivors. Cancer. 2010 Feb 01; 116(3):592-9. Su HI, Sammel MD, Green J, Velders L, Stankiewicz C, Matro J, Freeman EW, Gracia CR, DeMichele A. PMID: 19918920; PMCID: PMC2815049.

View in: PubMed Mentions: 34 Fields:
Neo Neoplasms