Hubert Chen

SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
ORCID ORCID Icon0000-0002-7599-7218 Additional info
vCardDownload vCard

    Collapse Biography 
    Collapse Education and Training
    Stanford University, Stanford, CABAS
    Columbia University, New York, NYMD
    Massachusetts General Hospital, Boston, MAMedicine
    UC San Francisco, San Francisco, CAEndocrinology, Diabetes, Metabolism
    Gladstone Institutes, San Francisco, CA

    Collapse Overview 

    Collapse Featured Content 
    Collapse Featured Videos

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Safety and immunogenicity of Px563L, a recombinant anthrax vaccine candidate, in a two-dose regimen for post-exposure prophylaxis in healthy adults. Vaccine. 2021; 42(39):6333-6339. JC Schneider, HC Chen, E Bautista, D Retallack. View Publication.
    2. Safety and immunogenicity of Px563L, a recombinant anthrax vaccine candidate, in a two-dose regimen for post-exposure prophylaxis in healthy adults. Vaccine. 2021 10 08; 39(42):6333-6339. Schneider JC, Chen HC, Bautista E, Retallack D. PMID: 34544599.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    3. Week 4 Liver Fat Reduction on MRI as an Early Predictor of Treatment Response in Participants with Nonalcoholic Steatohepatitis. Radiology. 2021 08; 300(2):361-368. Jiang H, Chen HC, Lafata KJ, Bashir MR. PMID: 34060937.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCTClinical Trials
    4. A structurally optimized FXR agonist, MET409, reduced liver fat content over 12 weeks in patients with non-alcoholic steatohepatitis. J Hepatol. 2021 07; 75(1):25-33. Harrison SA, Bashir MR, Lee KJ, Shim-Lopez J, Lee J, Wagner B, Smith ND, Chen HC, Lawitz EJ. PMID: 33581174.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    5. Role of islet-, gut-, and adipocyte-derived hormones in the central control of food intake and body weight: implications for an integrated neurohormonal approach to obesity pharmacotherapy. Curr Diabetes Rev. 2008 May; 4(2):79-91. Chen HC, Roth JD, Schroeder BE, Weyer C. PMID: 18473755.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    6. Enhancing energy and glucose metabolism by disrupting triglyceride synthesis: Lessons from mice lacking DGAT1. Nutr Metab (Lond). 2006 Jan 31; 3:10. Chen HC. PMID: 16448557; PMCID: PMC1382234.
      View in: PubMed   Mentions: 8  
    7. Inhibition of triglyceride synthesis as a treatment strategy for obesity: lessons from DGAT1-deficient mice. Arterioscler Thromb Vasc Biol. 2005 Mar; 25(3):482-6. Chen HC, Farese RV. PMID: 15569818.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimals
    8. Role of adipocyte-derived factors in enhancing insulin signaling in skeletal muscle and white adipose tissue of mice lacking Acyl CoA:diacylglycerol acyltransferase 1. Diabetes. 2004 Jun; 53(6):1445-51. Chen HC, Rao M, Sajan MP, Standaert M, Kanoh Y, Miura A, Farese RV, Farese RV. PMID: 15161747.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    9. Insulin-induced activation of atypical protein kinase C, but not protein kinase B, is maintained in diabetic (ob/ob and Goto-Kakazaki) liver. Contrasting insulin signaling patterns in liver versus muscle define phenotypes of type 2 diabetic and high fat-induced insulin-resistant states. J Biol Chem. 2004 Jun 11; 279(24):24929-34. Standaert ML, Sajan MP, Miura A, Kanoh Y, Chen HC, Farese RV, Farese RV. PMID: 15069067.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    10. Obesity resistance and enhanced glucose metabolism in mice transplanted with white adipose tissue lacking acyl CoA:diacylglycerol acyltransferase 1. J Clin Invest. 2003 Jun; 111(11):1715-22. Chen HC, Jensen DR, Myers HM, Eckel RH, Farese RV. PMID: 12782674; PMCID: PMC156099.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    11. Dissociation of obesity and impaired glucose disposal in mice overexpressing acyl coenzyme a:diacylglycerol acyltransferase 1 in white adipose tissue. Diabetes. 2002 Nov; 51(11):3189-95. Chen HC, Stone SJ, Zhou P, Buhman KK, Farese RV. PMID: 12401709.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    12. Analysis of energy expenditure at different ambient temperatures in mice lacking DGAT1. Am J Physiol Endocrinol Metab. 2003 Jan; 284(1):E213-8. Chen HC, Ladha Z, Smith SJ, Farese RV. PMID: 12388146.
      View in: PubMed   Mentions: 31     Fields:    Translation:Animals
    13. Deficiency of acyl coenzyme a:diacylglycerol acyltransferase 1 increases leptin sensitivity in murine obesity models. Endocrinology. 2002 Aug; 143(8):2893-8. Chen HC, Ladha Z, Farese RV. PMID: 12130553.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    14. Fatty acids, triglycerides, and glucose metabolism: recent insights from knockout mice. Curr Opin Clin Nutr Metab Care. 2002 Jul; 5(4):359-63. Chen HC, Farese RV. PMID: 12107369.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    15. Determination of adipocyte size by computer image analysis. J Lipid Res. 2002 Jun; 43(6):986-9. Chen HC, Farese RV. PMID: 12032175.
      View in: PubMed   Mentions: 70     Fields:    Translation:AnimalsCells
    16. Activation of the ERK pathway and atypical protein kinase C isoforms in exercise- and aminoimidazole-4-carboxamide-1-beta-D-riboside (AICAR)-stimulated glucose transport. J Biol Chem. 2002 Jun 28; 277(26):23554-62. Chen HC, Bandyopadhyay G, Sajan MP, Kanoh Y, Standaert M, Farese RV, Farese RV. PMID: 11978788.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    17. Increased insulin and leptin sensitivity in mice lacking acyl CoA:diacylglycerol acyltransferase 1. J Clin Invest. 2002 Apr; 109(8):1049-55. Chen HC, Smith SJ, Ladha Z, Jensen DR, Ferreira LD, Pulawa LK, McGuire JG, Pitas RE, Eckel RH, Farese RV. PMID: 11956242; PMCID: PMC150948.
      View in: PubMed   Mentions: 107     Fields:    Translation:HumansAnimalsCells
    18. Leptin modulates the effects of acyl CoA:diacylglycerol acyltransferase deficiency on murine fur and sebaceous glands. J Clin Invest. 2002 Jan; 109(2):175-81. Chen HC, Smith SJ, Tow B, Elias PM, Farese RV. PMID: 11805129; PMCID: PMC150839.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    19. Turning WAT into BAT gets rid of fat. Nat Med. 2001 Oct; 7(10):1102-3. Chen HC, Farese RV. PMID: 11590426.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    20. Molecular mechanisms of sterol absorption. J Nutr. 2001 Oct; 131(10):2603-5. Chen HC. PMID: 11584078.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    21. The enzymes of neutral lipid synthesis. J Biol Chem. 2001 Nov 02; 276(44):40369-72. Buhman KK, Chen HC, Farese RV. PMID: 11544264.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimalsCells
    22. DGAT and triglyceride synthesis: a new target for obesity treatment? Trends Cardiovasc Med. 2000 Jul; 10(5):188-92. Chen HC, Farese RV. PMID: 11282293.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    23. Obesity resistance and multiple mechanisms of triglyceride synthesis in mice lacking Dgat. Nat Genet. 2000 May; 25(1):87-90. Smith SJ, Cases S, Jensen DR, Chen HC, Sande E, Tow B, Sanan DA, Raber J, Eckel RH, Farese RV. PMID: 10802663.
      View in: PubMed   Mentions: 277     Fields:    Translation:AnimalsCells
    24. Hashimoto's encephalopathy. South Med J. 2000 May; 93(5):504-6. Chen HC, Marsharani U. PMID: 10832952.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    25. Steroid hormones: Interactions with membrane-bound receptors. Curr Biol. 1999 Jul 01; 9(13):R478-81. Chen HC, Farese RV. PMID: 10395533.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    Hubert's Networks
    Concepts (171)
    Derived automatically from this person's publications.
    Explore
    _
    Co-Authors (2)
    People in Profiles who have published with this person.
    Explore
    _
    Similar People (60)
    People who share similar concepts with this person.
    Explore
    _
    Same Department
    Search Department
    _

    UCSD Profiles is managed by the UC San Diego Altman Clinical and Translational Research Institute (ACTRI).
    This site is running Profiles RNS version UCSF-v3.1.0-5-g94c7c43e on PROFILES-PWEB04. We use cookies to operate our website. We also use cookies to analyze our site’s performance and improve your experience on our site. For more information about how we use cookies, please see our Website Terms of Use.

    Copyright © The Regents of the University of California