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    Hiromi Kumamaru

    TitlePostdoctoral Scholar
    SchoolUniversity of California, San Diego
    DepartmentNeurosciences
    Address9500 Gilman Drive #0624
    CA La Jolla 92093
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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Saito T, Hara M, Kumamaru H, Kobayakawa K, Yokota K, Kijima K, Yoshizaki S, Harimaya K, Matsumoto Y, Kawaguchi K, Hayashida M, Inagaki Y, Shiba K, Nakashima Y, Okada S. Macrophage Infiltration is a Causative Factor for Ligamentum Flavum Hypertrophy through the Activation of Collagen Production in Fibroblasts. Am J Pathol. 2017 Sep 18. PMID: 28935572.
        View in: PubMed
      2. Lu P, Ceto S, Wang Y, Graham L, Wu D, Kumamaru H, Staufenberg E, Tuszynski MH. Prolonged human neural stem cell maturation supports recovery in injured rodent CNS. J Clin Invest. 2017 Sep 01; 127(9):3287-3299. PMID: 28825600.
        View in: PubMed
      3. Renault-Mihara F, Mukaino M, Shinozaki M, Kumamaru H, Kawase S, Baudoux M, Ishibashi T, Kawabata S, Nishiyama Y, Sugai K, Yasutake K, Okada S, Nakamura M, Okano H. Regulation of RhoA by STAT3 coordinates glial scar formation. J Cell Biol. 2017 Aug 07; 216(8):2533-2550. PMID: 28642362.
        View in: PubMed
      4. Hara M, Kobayakawa K, Ohkawa Y, Kumamaru H, Yokota K, Saito T, Kijima K, Yoshizaki S, Harimaya K, Nakashima Y, Okada S. Interaction of reactive astrocytes with type I collagen induces astrocytic scar formation through the integrin-N-cadherin pathway after spinal cord injury. Nat Med. 2017 Jul; 23(7):818-828. PMID: 28628111.
        View in: PubMed
      5. Adler AF, Lee-Kubli C, Kumamaru H, Kadoya K, Tuszynski MH. Comprehensive Monosynaptic Rabies Virus Mapping of Host Connectivity with Neural Progenitor Grafts after Spinal Cord Injury. Stem Cell Reports. 2017 Jun 06; 8(6):1525-1533. PMID: 28479302.
        View in: PubMed
      6. Kadoya K, Lu P, Nguyen K, Lee-Kubli C, Kumamaru H, Yao L, Knackert J, Poplawski G, Dulin JN, Strobl H, Takashima Y, Biane J, Conner J, Zhang SC, Tuszynski MH. Spinal cord reconstitution with homologous neural grafts enables robust corticospinal regeneration. Nat Med. 2016 May; 22(5):479-87. PMID: 27019328; PMCID: PMC4860037.
      7. Kobayakawa K, Kumamaru H, Saiwai H, Kubota K, Ohkawa Y, Kishimoto J, Yokota K, Ideta R, Shiba K, Tozaki-Saitoh H, Inoue K, Iwamoto Y, Okada S. Acute hyperglycemia impairs functional improvement after spinal cord injury in mice and humans. Sci Transl Med. 2014 Oct 01; 6(256):256ra137. PMID: 25273098.
        View in: PubMed
      8. Kumamaru H, Saiwai H, Kubota K, Kobayakawa K, Yokota K, Ohkawa Y, Shiba K, Iwamoto Y, Okada S. Therapeutic activities of engrafted neural stem/precursor cells are not dormant in the chronically injured spinal cord. Stem Cells. 2013 Aug; 31(8):1535-47. PMID: 23606608.
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      9. Saiwai H, Kumamaru H, Ohkawa Y, Kubota K, Kobayakawa K, Yamada H, Yokomizo T, Iwamoto Y, Okada S. Ly6C+ Ly6G- Myeloid-derived suppressor cells play a critical role in the resolution of acute inflammation and the subsequent tissue repair process after spinal cord injury. J Neurochem. 2013 Apr; 125(1):74-88. PMID: 23278273.
        View in: PubMed
      10. Kubota K, Saiwai H, Kumamaru H, Kobayakawa K, Maeda T, Matsumoto Y, Harimaya K, Iwamoto Y, Okada S. Neurological recovery is impaired by concurrent but not by asymptomatic pre-existing spinal cord compression after traumatic spinal cord injury. Spine (Phila Pa 1976). 2012 Aug 01; 37(17):1448-55. PMID: 22414995.
        View in: PubMed
      11. Kubota K, Saiwai H, Kumamaru H, Maeda T, Ohkawa Y, Aratani Y, Nagano T, Iwamoto Y, Okada S. Myeloperoxidase exacerbates secondary injury by generating highly reactive oxygen species and mediating neutrophil recruitment in experimental spinal cord injury. Spine (Phila Pa 1976). 2012 Jul 15; 37(16):1363-9. PMID: 22322369.
        View in: PubMed
      12. Kumamaru H, Saiwai H, Kobayakawa K, Kubota K, van Rooijen N, Inoue K, Iwamoto Y, Okada S. Liposomal clodronate selectively eliminates microglia from primary astrocyte cultures. J Neuroinflammation. 2012 May 31; 9:116. PMID: 22651847; PMCID: PMC3419615.
      13. Harada A, Okada S, Konno D, Odawara J, Yoshimi T, Yoshimura S, Kumamaru H, Saiwai H, Tsubota T, Kurumizaka H, Akashi K, Tachibana T, Imbalzano AN, Ohkawa Y. Chd2 interacts with H3.3 to determine myogenic cell fate. EMBO J. 2012 Jun 29; 31(13):2994-3007. PMID: 22569126; PMCID: PMC3395093.
      14. Kumamaru H, Saiwai H, Ohkawa Y, Yamada H, Iwamoto Y, Okada S. Age-related differences in cellular and molecular profiles of inflammatory responses after spinal cord injury. J Cell Physiol. 2012 Apr; 227(4):1335-46. PMID: 21604270.
        View in: PubMed
      15. Kubota K, Okada S, Maeda T, Matsumoto Y, Sakamoto A, Harimaya K, Saiwai H, Kumamaru H, Oda Y, Iwamoto Y. Extradural nodular fasciitis arising in the spinal canal. Spine (Phila Pa 1976). 2012 Jan 15; 37(2):E133-7. PMID: 21629160.
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      16. Kumamaru H, Ohkawa Y, Saiwai H, Yamada H, Kubota K, Kobayakawa K, Akashi K, Okano H, Iwamoto Y, Okada S. Direct isolation and RNA-seq reveal environment-dependent properties of engrafted neural stem/progenitor cells. Nat Commun. 2012; 3:1140. PMID: 23072808.
        View in: PubMed
      17. Okada S, Saiwai H, Kumamaru H, Kubota K, Harada A, Yamaguchi M, Iwamoto Y, Ohkawa Y. Flow cytometric sorting of neuronal and glial nuclei from central nervous system tissue. J Cell Physiol. 2011 Feb; 226(2):552-8. PMID: 20717962.
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      18. Saiwai H, Ohkawa Y, Yamada H, Kumamaru H, Harada A, Okano H, Yokomizo T, Iwamoto Y, Okada S. The LTB4-BLT1 axis mediates neutrophil infiltration and secondary injury in experimental spinal cord injury. Am J Pathol. 2010 May; 176(5):2352-66. PMID: 20304963; PMCID: PMC2861100.
      19. Harada A, Okada S, Odawara J, Kumamaru H, Saiwai H, Aoki M, Nakamura M, Nishiyama Y, Ohkawa Y. Production of a rat monoclonal antibody specific for Myf5. Hybridoma (Larchmt). 2010 Feb; 29(1):59-62. PMID: 20199153.
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      20. Okada S, Maeda T, Ohkawa Y, Harimaya K, Saiwai H, Kumamaru H, Matsumoto Y, Doi T, Ueta T, Shiba K, Iwamoto Y. Does ossification of the posterior longitudinal ligament affect the neurological outcome after traumatic cervical cord injury? Spine (Phila Pa 1976). 2009 May 15; 34(11):1148-52. PMID: 19444061.
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      21. Kumagai H, Hayashi K, Kumamaru H, Saruta T. Amlodipine is comparable to angiotensin-converting enzyme inhibitor for long-term renoprotection in hypertensive patients with renal dysfunction: a one-year, prospective, randomized study. Am J Hypertens. 2000 Sep; 13(9):980-5. PMID: 10981547.
        View in: PubMed
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