Hao Sun

Title(s)Assistant Researcher, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
ORCID ORCID Icon0000-0002-4790-8847 Additional info
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Mitofusin-2 regulates leukocyte adhesion and β2 integrin activation. J Leukoc Biol. 2022 Apr; 111(4):771-791. Liu W, Hsu AY, Wang Y, Lin T, Sun H, Pachter JS, Groisman A, Imperioli M, Yungher FW, Hu L, Wang P, Deng Q, Fan Z. PMID: 34494308; PMCID: PMC8901796.
      View in: PubMed   Mentions:    Fields:    
    2. Astrocytes propel neurovascular dysfunction during cerebral cavernous malformation lesion formation. J Clin Invest. 2021 07 01; 131(13). Lopez-Ramirez MA, Lai CC, Soliman SI, Hale P, Pham A, Estrada EJ, McCurdy S, Girard R, Verma R, Moore T, Lightle R, Hobson N, Shenkar R, Poulsen O, Haddad GG, Daneman R, Gongol B, Sun H, Lagarrigue F, Awad IA, Ginsberg MH. PMID: 34043589; PMCID: PMC8245174.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    3. β2 integrin activation and signal transduction in leukocyte recruitment. Am J Physiol Cell Physiol. 2021 08 01; 321(2):C308-C316. Sun H, Hu L, Fan Z. PMID: 34133240; PMCID: PMC8424673.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    4. Editorial: Imaging and Mechanism of Leukocyte Recruitment and Function in Inflammation and Infections. Front Cell Dev Biol. 2021; 9:690003. Sun H, Huo Y, Fan Z. PMID: 34026766; PMCID: PMC8138456.
      View in: PubMed   Mentions:
    5. The Activation and Regulation of β2 Integrins in Phagocytes and Phagocytosis. Front Immunol. 2021; 12:633639. Sun H, Zhi K, Hu L, Fan Z. PMID: 33868253; PMCID: PMC8044391.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    6. Visualization of integrin molecules by fluorescence imaging and techniques. Biocell. 2021; 45(2):229-257. Cai C, Sun H, Hu L, Fan Z. PMID: 34219865; PMCID: PMC8249084.
      View in: PubMed   Mentions:    Fields:    
    7. Inhibition of the HEG1-KRIT1 interaction increases KLF4 and KLF2 expression in endothelial cells. FASEB Bioadv. 2021 May; 3(5):334-355. Lopez-Ramirez MA, McCurdy S, Li W, Haynes MK, Hale P, Francisco K, Oukoloff K, Bautista M, Choi CHJ, Sun H, Gongol B, Shyy JY, Ballatore C, Sklar LA, Gingras AR. PMID: 33977234; PMCID: PMC8103725.
      View in: PubMed   Mentions:
    8. Distinct integrin activation pathways for effector and regulatory T cell trafficking and function. J Exp Med. 2021 02 01; 218(2). Sun H, Lagarrigue F, Wang H, Fan Z, Lopez-Ramirez MA, Chang JT, Ginsberg MH. PMID: 33104169; PMCID: PMC7590511.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    9. Kindlin-3 recruitment to the plasma membrane precedes high-affinity β2-integrin and neutrophil arrest from rolling. Blood. 2021 01 07; 137(1):29-38. Wen L, Marki A, Roy P, McArdle S, Sun H, Fan Z, Gingras AR, Ginsberg MH, Ley K. PMID: 32777822; PMCID: PMC7808012.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    10. A stem cell reporter based platform to identify and target drug resistant stem cells in myeloid leukemia. Nat Commun. 2020 11 26; 11(1):5998. Spinler K, Bajaj J, Ito T, Zimdahl B, Hamilton M, Ahmadi A, Koechlein CS, Lytle N, Kwon HY, Anower-E-Khuda F, Sun H, Blevins A, Weeks J, Kritzik M, Karlseder J, Ginsberg MH, Park PW, Esko JD, Reya T. PMID: 33243988; PMCID: PMC7691523.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    11. Talin-1 is the principal platelet Rap1 effector of integrin activation. Blood. 2020 09 03; 136(10):1180-1190. Lagarrigue F, Paul DS, Gingras AR, Valadez AJ, Sun H, Lin J, Cuevas MN, Ablack JN, Lopez-Ramirez MA, Bergmeier W, Ginsberg MH. PMID: 32518959; PMCID: PMC7472713.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    12. The Clinical Conundrum of Managing Ischemic Stroke in Patients with Immune Thrombocytopenia. Can J Neurol Sci. 2021 01; 48(1):38-46. Alrohimi A, Purdy K, Alqarni M, Alotaibi G, Blevins G, Butcher K, Rempel J, Wu C, Sun HL, Khan K. PMID: 32646527.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Isolation and Purification of Mouse Brain Endothelial Cells to Study Cerebral Cavernous Malformation Disease. Methods Mol Biol. 2020; 2152:139-150. Hale P, Soliman SI, Sun H, Lopez-Ramirez MA. PMID: 32524550.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    14. β7 Integrin Inhibition Can Increase Intestinal Inflammation by Impairing Homing of CD25hiFoxP3+ Regulatory T Cells. Cell Mol Gastroenterol Hepatol. 2020; 9(3):369-385. Sun H, Kuk W, Rivera-Nieves J, Lopez-Ramirez MA, Eckmann L, Ginsberg MH. PMID: 31707128; PMCID: PMC7016000.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    15. Frontline Science: A flexible kink in the transmembrane domain impairs β2 integrin extension and cell arrest from rolling. J Leukoc Biol. 2020 02; 107(2):175-183. Sun H, Fan Z, Gingras AR, Lopez-Ramirez MA, Ginsberg MH, Ley K. PMID: 31475386; PMCID: PMC6987018.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    16. Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos. Science. 2019 04 19; 364(6437):289-292. Zuo E, Sun Y, Wei W, Yuan T, Ying W, Sun H, Yuan L, Steinmetz LM, Li Y, Yang H. PMID: 30819928; PMCID: PMC7301308.
      View in: PubMed   Mentions: 194     Fields:    Translation:AnimalsCells
    17. High-Affinity Bent β2-Integrin Molecules in Arresting Neutrophils Face Each Other through Binding to ICAMs In cis. Cell Rep. 2019 01 02; 26(1):119-130.e5. Fan Z, Kiosses WB, Sun H, Orecchioni M, Ghosheh Y, Zajonc DM, Arnaout MA, Gutierrez E, Groisman A, Ginsberg MH, Ley K. PMID: 30605669; PMCID: PMC6625519.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    18. Rap1 binding to the talin 1 F0 domain makes a minimal contribution to murine platelet GPIIb-IIIa activation. Blood Adv. 2018 09 25; 2(18):2358-2368. Lagarrigue F, Gingras AR, Paul DS, Valadez AJ, Cuevas MN, Sun H, Lopez-Ramirez MA, Goult BT, Shattil SJ, Bergmeier W, Ginsberg MH. PMID: 30242097; PMCID: PMC6156890.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    19. Integrin α4β7 switches its ligand specificity via distinct conformer-specific activation. J Cell Biol. 2018 08 06; 217(8):2799-2812. Wang S, Wu C, Zhang Y, Zhong Q, Sun H, Cao W, Ge G, Li G, Zhang XF, Chen J. PMID: 29789438; PMCID: PMC6080939.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    20. Transmission of integrin β7 transmembrane domain topology enables gut lymphoid tissue development. J Cell Biol. 2018 04 02; 217(4):1453-1465. Sun H, Lagarrigue F, Gingras AR, Fan Z, Ley K, Ginsberg MH. PMID: 29535192; PMCID: PMC5881498.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    21. Bile acids evoke placental inflammation by activating Gpbar1/NF-κB pathway in intrahepatic cholestasis of pregnancy. J Mol Cell Biol. 2016 12; 8(6):530-541. Zhang Y, Pan Y, Lin C, Zheng Y, Sun H, Zhang H, Wang J, Yuan M, Duan T, Du Q, Chen J. PMID: 27402811.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    22. Regulatory T-cell depletion in the gut caused by integrin β7 deficiency exacerbates DSS colitis by evoking aberrant innate immunity. Mucosal Immunol. 2016 Mar; 9(2):391-400. Zhang HL, Zheng YJ, Pan YD, Xie C, Sun H, Zhang YH, Yuan MY, Song BL, Chen JF. PMID: 26220167.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    23. Distinct chemokine signaling regulates integrin ligand specificity to dictate tissue-specific lymphocyte homing. Dev Cell. 2014 Jul 14; 30(1):61-70. Sun H, Liu J, Zheng Y, Pan Y, Zhang K, Chen J. PMID: 24954024.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    24. The hydrophobic contacts between the center of the βI domain and the α1/α7 helices are crucial for the low-affinity state of integrin α4 β7. FEBS J. 2014 Jul; 281(13):2915-26. Liu J, Fu T, Peng B, Sun H, Chu H, Li G, Chen J. PMID: 24802248.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    25. Structural specializations of α(4)β(7), an integrin that mediates rolling adhesion. J Cell Biol. 2012 Jan 09; 196(1):131-46. Yu Y, Zhu J, Mi LZ, Walz T, Sun H, Chen J, Springer TA. PMID: 22232704; PMCID: PMC3255974.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    26. The CC' and DE loops in Ig domains 1 and 2 of MAdCAM-1 play different roles in MAdCAM-1 binding to low- and high-affinity integrin alpha4beta7. J Biol Chem. 2011 Apr 08; 286(14):12086-92. Sun H, Wu Y, Qi J, Pan Y, Ge G, Chen J. PMID: 21296888; PMCID: PMC3069412.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
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