Floyd Sarsoza

Title(s)	SRA 3, Neurosciences
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
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Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Hippocampal Reduction of α-Synuclein via RNA Interference Improves Neuropathology in Alzheimer's Disease Mice. J Alzheimers Dis. 2023; 95(1):349-361. Leitão ADG, Spencer B, Sarsoza F, Ngolab J, Amalraj J, Masliah E, Wu C, Rissman RA. PMID: 37522208; PMCID: PMC10578232.

View in: PubMed Mentions: Fields:
Ger Geriatrics Neu Neurology
Translation:Animals
Leukocyte surface biomarkers implicate deficits of innate immunity in sporadic Alzheimer's disease. Alzheimers Dement. 2023 05; 19(5):2084-2094. Huang X, Li Y, Fowler C, Doecke JD, Lim YY, Drysdale C, Zhang V, Park K, Trounson B, Pertile K, Rumble R, Pickering JW, Rissman RA, Sarsoza F, Abdel-Latif S, Lin Y, Doré V, Villemagne V, Rowe CC, Fripp J, Martins R, Wiley JS, Maruff P, Mintzer JE, Masters CL, Gu BJ. PMID: 36349985; PMCID: PMC10166765.

View in: PubMed Mentions: 2 Fields:
Neu Neurology Psy Psychiatry
Translation:Humans Cells
Myosin Transducer Inter-Strand Communication Is Critical for Normal ATPase Activity and Myofibril Structure. Biology (Basel). 2022 Jul 29; 11(8). Kronert WA, Hsu KH, Madan A, Sarsoza F, Cammarato A, Bernstein SI. PMID: 36009764; PMCID: PMC9404822.

View in: PubMed Mentions:
Modulation of Amyloid-β and Tau in Alzheimer's Disease Plasma Neuronal-Derived Extracellular Vesicles by Cerebrolysin® and Donepezil. J Alzheimers Dis. 2022; 90(2):705-717. Alvarez XA, Winston CN, Barlow JW, Sarsoza FM, Alvarez I, Aleixandre M, Linares C, García-Fantini M, Kastberger B, Winter S, Rissman RA. PMID: 36155516; PMCID: PMC9697063.

View in: PubMed Mentions: 2 Fields:
Ger Geriatrics Neu Neurology
Translation:Humans Cells
Transcriptome analyses reveal tau isoform-driven changes in transposable element and gene expression. PLoS One. 2021; 16(9):e0251611. Grundman J, Spencer B, Sarsoza F, Rissman RA. PMID: 34587152; PMCID: PMC8480850.

View in: PubMed Mentions: 4 Fields:
Med Medicine (General)Sci Science
Translation:Humans Cells
Mutant three-repeat tau expression initiates retinal ganglion cell death through Caspase-2. Neurobiol Dis. 2021 05; 152:105277. Ngolab J, Canchi S, Rasool S, Elmaarouf A, Thomas K, Sarsoza F, Grundman J, Mante M, Florio J, Nandankar N, Korouri S, Zago W, Masliah E, Rissman RA. PMID: 33516874; PMCID: PMC8373010.

View in: PubMed Mentions: 2 Fields:
Neu Neurology
Translation:Humans Animals Cells
Drosophila myosin mutants model the disparate severity of type 1 and type 2B distal arthrogryposis and indicate an enhanced actin affinity mechanism. Skelet Muscle. 2020 08 15; 10(1):24. Guo Y, Kronert WA, Hsu KH, Huang A, Sarsoza F, Bell KM, Suggs JA, Swank DM, Bernstein SI. PMID: 32799913; PMCID: PMC7429702.

View in: PubMed Mentions: 3 Fields:
Phy Physiology
Translation:Animals Cells
Reductions in ATPase activity, actin sliding velocity, and myofibril stability yield muscle dysfunction in Drosophila models of myosin-based Freeman-Sheldon syndrome. Mol Biol Cell. 2019 01 01; 30(1):30-41. Rao DS, Kronert WA, Guo Y, Hsu KH, Sarsoza F, Bernstein SI. PMID: 30379605; PMCID: PMC6337914.

View in: PubMed Mentions: 11 Fields:
Cel Cell Biology Mol Molecular Biology
Translation:Animals Cells
Interacting-heads motif has been conserved as a mechanism of myosin II inhibition since before the origin of animals. Proc Natl Acad Sci U S A. 2018 02 27; 115(9):E1991-E2000. Lee KH, Sulbarán G, Yang S, Mun JY, Alamo L, Pinto A, Sato O, Ikebe M, Liu X, Korn ED, Sarsoza F, Bernstein SI, Padrón R, Craig R. PMID: 29444861; PMCID: PMC5834683.

View in: PubMed Mentions: 53 Fields:
Sci Science
Translation:Animals Cells
Myosin storage myopathy mutations yield defective myosin filament assembly in vitro and disrupted myofibrillar structure and function in vivo. Hum Mol Genet. 2017 12 15; 26(24):4799-4813. Viswanathan MC, Tham RC, Kronert WA, Sarsoza F, Trujillo AS, Cammarato A, Bernstein SI. PMID: 28973424; PMCID: PMC5886249.

View in: PubMed Mentions: 10 Fields:
Gen Genetics Mol Molecular Biology
Translation:Humans Animals Cells
Effect of potent γ-secretase modulator in human neurons derived from multiple presenilin 1-induced pluripotent stem cell mutant carriers. JAMA Neurol. 2014 Dec; 71(12):1481-9. Liu Q, Waltz S, Woodruff G, Ouyang J, Israel MA, Herrera C, Sarsoza F, Tanzi RE, Koo EH, Ringman JM, Goldstein LS, Wagner SL, Yuan SH. PMID: 25285942; PMCID: PMC4374637.

View in: PubMed Mentions: 49 Fields:
Neu Neurology
Translation:Humans Cells
Amyloid precursor protein (APP) regulates synaptic structure and function. Mol Cell Neurosci. 2012 Aug; 51(1-2):43-52. Tyan SH, Shih AY, Walsh JJ, Maruyama H, Sarsoza F, Ku L, Eggert S, Hof PR, Koo EH, Dickstein DL. PMID: 22884903; PMCID: PMC3538857.

View in: PubMed Mentions: 90 Fields:
Cel Cell Biology Mol Molecular Biology Neu Neurology
Translation:Animals Cells
Deletion of the amyloid precursor-like protein 2 (APLP2) does not affect hippocampal neuron morphology or function. Mol Cell Neurosci. 2012 Apr; 49(4):448-55. Midthune B, Tyan SH, Walsh JJ, Sarsoza F, Eggert S, Hof PR, Dickstein DL, Koo EH. PMID: 22353605; PMCID: PMC3348437.

View in: PubMed Mentions: 18 Fields:
Cel Cell Biology Mol Molecular Biology Neu Neurology
Translation:Animals Cells
Amyloid-beta peptide and oligomers in the brain and cerebrospinal fluid of aged canines. J Alzheimers Dis. 2010; 20(2):637-46. Head E, Pop V, Sarsoza F, Kayed R, Beckett TL, Studzinski CM, Tomic JL, Glabe CG, Murphy MP. PMID: 20164551; PMCID: PMC2903832.

View in: PubMed Mentions: 30 Fields:
Ger Geriatrics Neu Neurology
Translation:Animals
A fibril-specific, conformation-dependent antibody recognizes a subset of Abeta plaques in Alzheimer disease, Down syndrome and Tg2576 transgenic mouse brain. Acta Neuropathol. 2009 Oct; 118(4):505-17. Sarsoza F, Saing T, Kayed R, Dahlin R, Dick M, Broadwater-Hollifield C, Mobley S, Lott I, Doran E, Gillen D, Anderson-Bergman C, Cribbs DH, Glabe C, Head E. PMID: 19360426; PMCID: PMC2737113.

View in: PubMed Mentions: 27 Fields:
Neu Neurology
Translation:Humans Animals Cells
Annular protofibrils are a structurally and functionally distinct type of amyloid oligomer. J Biol Chem. 2009 Feb 13; 284(7):4230-7. Kayed R, Pensalfini A, Margol L, Sokolov Y, Sarsoza F, Head E, Hall J, Glabe C. PMID: 19098006; PMCID: PMC2640961.

View in: PubMed Mentions: 139 Fields:
Bio Biochemistry
Translation:Humans Cells
A two-year study with fibrillar beta-amyloid (Abeta) immunization in aged canines: effects on cognitive function and brain Abeta. J Neurosci. 2008 Apr 02; 28(14):3555-66. Head E, Pop V, Vasilevko V, Hill M, Saing T, Sarsoza F, Nistor M, Christie LA, Milton S, Glabe C, Barrett E, Cribbs D. PMID: 18385314; PMCID: PMC6671080.

View in: PubMed Mentions: 51 Fields:
Neu Neurology
Translation:Animals Cells PHPublic Health
Synaptic proteins, neuropathology and cognitive status in the oldest-old. Neurobiol Aging. 2009 Jul; 30(7):1125-34. Head E, Corrada MM, Kahle-Wrobleski K, Kim RC, Sarsoza F, Goodus M, Kawas CH. PMID: 18006193; PMCID: PMC7295175.

View in: PubMed Mentions: 60 Fields:
Ger Geriatrics Neu Neurology Phy Physiology
Translation:Humans Cells
Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers. Mol Neurodegener. 2007 Sep 26; 2:18. Kayed R, Head E, Sarsoza F, Saing T, Cotman CW, Necula M, Margol L, Wu J, Breydo L, Thompson JL, Rasool S, Gurlo T, Butler P, Glabe CG. PMID: 17897471; PMCID: PMC2100048.

View in: PubMed Mentions: 361 Fields:
Mol Molecular Biology Neu Neurology
Alpha- and beta-secretase activity as a function of age and beta-amyloid in Down syndrome and normal brain. Neurobiol Aging. 2007 Oct; 28(10):1493-506. Nistor M, Don M, Parekh M, Sarsoza F, Goodus M, Lopez GE, Kawas C, Leverenz J, Doran E, Lott IT, Hill M, Head E. PMID: 16904243; PMCID: PMC3375834.

View in: PubMed Mentions: 57 Fields:
Ger Geriatrics Neu Neurology Phy Physiology
Translation:Humans Cells
Immunization with fibrillar Abeta(1-42) in young and aged canines: Antibody generation and characteristics, and effects on CSF and brain Abeta. Vaccine. 2006 Apr 05; 24(15):2824-34. Head E, Barrett EG, Murphy MP, Das P, Nistor M, Sarsoza F, Glabe CC, Kayed R, Milton S, Vasilevko V, Milgram NW, Agadjanyan MG, Cribbs DH, Cotman CW. PMID: 16460841.

View in: PubMed Mentions: 7 Fields:
All Allergy and Immunology
Translation:Humans Animals
Caspase-cleaved tau accumulation in neurodegenerative diseases associated with tau and alpha-synuclein pathology. Acta Neuropathol. 2005 Aug; 110(2):135-44. Newman J, Rissman RA, Sarsoza F, Kim RC, Dick M, Bennett DA, Cotman CW, Rohn TT, Head E. PMID: 15986225.

View in: PubMed Mentions: 26 Fields:
Neu Neurology
Translation:Humans Cells
Beta-amyloid deposition and tau phosphorylation in clinically characterized aged cats. Neurobiol Aging. 2005 May; 26(5):749-63. Head E, Moffat K, Das P, Sarsoza F, Poon WW, Landsberg G, Cotman CW, Murphy MP. PMID: 15708450.

View in: PubMed Mentions: 27 Fields:
Ger Geriatrics Neu Neurology Phy Physiology
Translation:Humans Animals Cells
Reduced neuronal expression of synaptic transmission modulator HNK-1/neural cell adhesion molecule as a potential consequence of amyloid beta-mediated oxidative stress: a proteomic approach. J Neurochem. 2005 Feb; 92(4):705-17. Thomas SN, Soreghan BA, Nistor M, Sarsoza F, Head E, Yang AJ. PMID: 15686472.

View in: PubMed Mentions: 8 Fields:
Che Chemistry Neu Neurology
Translation:Animals Cells
The myosin converter domain modulates muscle performance. Nat Cell Biol. 2002 Apr; 4(4):312-6. Swank DM, Knowles AF, Suggs JA, Sarsoza F, Lee A, Maughan DW, Bernstein SI. PMID: 11901423.

View in: PubMed Mentions: 48 Fields:
Cel Cell Biology
Translation:Animals Cells