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Noninvasive pathway for stratifying fibrosis in suspected metabolic dysfunction and alcohol-associated liver disease (MetALD). Hepatol Commun. 2025 Jun 01; 9(6).
Díaz LA, Tavaglione F, Mittal N, Bettencourt R, Amangurbanova M, Johnson A, Marti-Aguado D, Tincopa M, Loomba R, Khan-Riches A, Madamba E, Siddiqi H, Richards L, Sirlin CB, Ajmera V, Loomba R. PMID: 40377491.
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Review Article: GLP-1 Receptor Agonists and Glucagon/GIP/GLP-1 Receptor Dual or Triple Agonists-Mechanism of Action and Emerging Therapeutic Landscape in MASLD. Aliment Pharmacol Ther. 2025 May 13.
Zafer M, Tavaglione F, Romero-Gómez M, Loomba R. PMID: 40364529.
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PubMed Mentions: Fields:
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An Expert Consensus Delphi Panel in MetALD: Opportunities and Challenges in Clinical Practice. Clin Gastroenterol Hepatol. 2025 Apr 30.
Diaz LA, Ajmera V, Arab JP, Huang DQ, Hsu C, Lee BP, Louvet A, Thiele M, Tavaglione F, Tincopa M, Pose E, Adams LA, Alazawi W, Arrese M, Bataller R, Duseja A, Liangpunsakul S, Lucey MR, Mathurin P, Mellinger J, Nakajima A, Ratziu V, Reau N, Rinella ME, Thursz M, Wong VW, Kamath PS, Loomba R. PMID: 40315973.
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PubMed Mentions: Fields:
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PNPLA3 I148M and Hepatocellular Carcinoma. Liver Int. 2025 Apr; 45(4):e70051.
Tavaglione F, Pennisi G, Pelusi S. PMID: 40029157.
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Translation:
Humans
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Letter on 'Head-To-Head Comparison Between Phosphatidylethanol Versus Indirect Alcohol Biomarkers for Diagnosis of MetALD Versus MASLD: A Prospective Study' Authors' Reply. Aliment Pharmacol Ther. 2025 Mar; 61(6):1084-1085.
Tavaglione F, Loomba R. PMID: 39957604.
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Editorial: Revolutionising Steatotic Liver Disease Diagnosis With Phosphatidylethanol-Authors' Reply. Aliment Pharmacol Ther. 2025 Mar; 61(6):1071-1072.
Tavaglione F, Loomba R. PMID: 39954266.
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PubMed Mentions: Fields:
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Publisher Correction: Partitioned polygenic risk scores identify distinct types of metabolic dysfunction-associated steatotic liver disease. Nat Med. 2025 Feb; 31(2):700.
Jamialahmadi O, De Vincentis A, Tavaglione F, Malvestiti F, Li-Gao R, Mancina RM, Alvarez M, Gelev K, Maurotti S, Vespasiani-Gentilucci U, Rosendaal FR, Kozlitina J, Pajukanta P, Pattou F, Valenti L, Romeo S. PMID: 39820106; PMCID: PMC11835728.
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PubMed Mentions: Fields:
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Design and rationale for a global novel non-invasive screening observational study using genetics and non-invasive methodologies to identify at-risk MASLD participants: The ALIGN study. Contemp Clin Trials Commun. 2025 Apr; 44:101437.
Daniels SJ, Nelander K, Eriksson J, Jermutus L, Saillard J, Oyesola S, Tavaglione F, Arrese M, Ladrón de Guevara AL, Vespasiani-Gentilucci U, Alkhouri N, Blau JE. PMID: 39916681; PMCID: PMC11800087.
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Head-to-Head Comparison Between Phosphatidylethanol Versus Indirect Alcohol Biomarkers for Diagnosis of MetALD Versus MASLD: A Prospective Study. Aliment Pharmacol Ther. 2025 Mar; 61(6):1043-1054.
Tavaglione F, Amangurbanova M, Yang AH, Tincopa MA, Ajmera V, Richards L, Butcher C, Hernandez C, Madamba E, Singh S, Bettencourt R, Sirlin CB, Loomba R. PMID: 39825487; PMCID: PMC11870800.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Machine Learning Reveals the Contribution of Lipoproteins to Liver Triglyceride Content and Inflammation. J Clin Endocrinol Metab. 2024 Dec 18; 110(1):218-227.
Tavaglione F, Marafioti G, Romeo S, Jamialahmadi O. PMID: 38833012; PMCID: PMC11651681.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Data-driven cluster analysis identifies distinct types of metabolic dysfunction-associated steatotic liver disease. Nat Med. 2024 Dec; 30(12):3624-3633.
Raverdy V, Tavaglione F, Chatelain E, Lassailly G, De Vincentis A, Vespasiani-Gentilucci U, Qadri SF, Caiazzo R, Verkindt H, Saponaro C, Kerr-Conte J, Baud G, Marciniak C, Chetboun M, Oukhouya-Daoud N, Blanck S, Vandel J, Olsson L, Chakaroun R, Gnemmi V, Leteurtre E, Lefebvre P, Haas JT, Yki-Järvinen H, Francque S, Staels B, Le Roux CW, Tremaroli V, Mathurin P, Marot G, Romeo S, Pattou F. PMID: 39653777; PMCID: PMC11645276.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Partitioned polygenic risk scores identify distinct types of metabolic dysfunction-associated steatotic liver disease. Nat Med. 2024 Dec; 30(12):3614-3623.
Jamialahmadi O, De Vincentis A, Tavaglione F, Malvestiti F, Li-Gao R, Mancina RM, Alvarez M, Gelev K, Maurotti S, Vespasiani-Gentilucci U, Rosendaal FR, Kozlitina J, Pajukanta P, Pattou F, Valenti L, Romeo S. PMID: 39653778; PMCID: PMC11645285.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Prevalence of steatotic liver disease, advanced fibrosis and cirrhosis among community-dwelling overweight and obese individuals in the USA. Gut. 2024 Nov 11; 73(12):2045-2053.
Yang AH, Tincopa MA, Tavaglione F, Ajmera VH, Richards LM, Amangurbanova M, Butcher C, Hernandez C, Madamba E, Singh S, Bettencourt R, Schnabl B, Sirlin CB, Loomba R. PMID: 39117370.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Emerging Combination of Saroglitazar and Vitamin E for the Treatment of NAFLD and NASH. J Clin Exp Hepatol. 2024 Sep-Oct; 14(5):101449.
Tavaglione F, Loomba R. PMID: 38881684; PMCID: PMC11170343.
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PubMed Mentions:
1
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Poor accuracy and sustainability of the first-step FIB4 EASL pathway for stratifying steatotic liver disease risk in the general population. Aliment Pharmacol Ther. 2024 06; 59(11):1402-1412.
De Vincentis A, Tavaglione F, Namba S, Kanai M, Okada Y, Kamatani Y, Maurotti S, Pedone C, Antonelli Incalzi R, Valenti L, Romeo S, Vespasiani-Gentilucci U. PMID: 38497224.
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PubMed Mentions:
1 Fields:
Translation:
HumansPHPublic Health
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Protein Phosphatase 1 Regulatory Subunit 3 Beta rs4240624 Genotype Is Associated With Gallstones and With Significant Changes in Bile Lipidome. Gastro Hep Adv. 2024; 3(5):594-601.
Männistö VT, Kaminska D, Haal S, Asteljoki J, Luukkonen PK, Käkelä P, Tavaglione F, van Weeghel M, Neuvonen M, Niemi M, Romeo S, Nieuwdorp M, Pihlajamäki J, Groen AK. PMID: 39165418; PMCID: PMC11330930.
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Non-invasive assessment of hepatic steatosis by ultrasound-derived fat fraction in individuals at high-risk for metabolic dysfunction-associated steatotic liver disease. Diabetes Metab Res Rev. 2024 Mar; 40(3):e3787.
Tavaglione F, Flagiello V, Terracciani F, Gallo P, Capparelli E, Spiezia C, De Vincentis A, Palermo A, Scriccia S, Galati G, Napoli N, Daniels SJ, Blau JE, Carlsson B, Khazrai YM, Incalzi RA, Picardi A, Vespasiani-Gentilucci U. PMID: 38461408.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Partitioned polygenic risk scores identify distinct types of metabolic dysfunction-associated steatotic liver disease. Res Sq. 2024 Feb 06.
Romeo S, Jamialahmadi O, De Vincentis A, Tavaglione F, Malvestiti F, Li-Gao R, Mancina R, Alvarez M, Gelev K, Maurotti S, Vespasiani-Gentilucci U, Rosendaal F, Kozlitina J, Pajukanta P, Pattou F, Valenti L. PMID: 38405802; PMCID: PMC10889080.
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IL32 downregulation lowers triglycerides and type I collagen in di-lineage human primary liver organoids. Cell Rep Med. 2024 01 16; 5(1):101352.
Sasidharan K, Caddeo A, Jamialahmadi O, Noto FR, Tomasi M, Malvestiti F, Ciociola E, Tavaglione F, Mancina RM, Cherubini A, Bianco C, Mirarchi A, Männistö V, Pihlajamäki J, Kärjä V, Grimaudo S, Luukkonen PK, Qadri S, Yki-Järvinen H, Petta S, Manfrini S, Vespasiani-Gentilucci U, Bruni V, Valenti L, Romeo S. PMID: 38232700; PMCID: PMC10829727.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Performance of non-invasive tests for liver fibrosis resolution after bariatric surgery. Metabolism. 2024 Apr; 153:155790.
Raverdy V, Tavaglione F, Chatelain E, Caiazzo R, Saponaro C, Lassailly G, Verkindt H, Baud G, Marciniak C, Chetboun M, Oukhouya-Daoud N, Gnemmi V, Leteurtre E, Duhamel A, Philippe M, Marot G, Romeo S, Pattou F. PMID: 38219973.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Predictors of controlled attenuation parameter in metabolic dysfunction. United European Gastroenterol J. 2024 04; 12(3):364-373.
Bianco C, Pelusi S, Margarita S, Tavaglione F, Jamialahmadi O, Malvestiti F, Periti G, Rondena J, Tomasi M, Carpani R, Ronzoni L, Vidali M, Ceriotti F, Fraquelli M, Vespasiani-Gentilucci U, Romeo S, Prati D, Valenti L. PMID: 38141028; PMCID: PMC11017762.
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PubMed Mentions:
3 Translation:
Humans
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Endocrine aspects of metabolic dysfunction-associated steatotic liver disease (MASLD): Beyond insulin resistance. J Hepatol. 2023 12; 79(6):1524-1541.
Hutchison AL, Tavaglione F, Romeo S, Charlton M. PMID: 37730124.
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PubMed Mentions:
44 Fields:
Translation:
HumansCells
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Reply to: "Fatty liver disease at the basis of cardiac remodelling and increased heart rate: Insights from the UK Biobank". Liver Int. 2023 06; 43(6):1362-1364.
Tavaglione F, Jamialahmadi O, Ljungman C, Romeo S. PMID: 37166135.
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PubMed Mentions: Fields:
Translation:
Humans
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Fatty liver disease genetic risk variants and interference on sex hormones. Liver Int. 2023 05; 43(5):958-961.
Tavaglione F, Jamialahmadi O, Valenti L, Romeo S. PMID: 37161848.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Programmed cell death 1 genetic variant and liver damage in nonalcoholic fatty liver disease. Liver Int. 2023 08; 43(8):1761-1771.
Pipitone RM, Malvestiti F, Pennisi G, Jamialahmadi O, Dongiovanni P, Bertolazzi G, Pihlajamäki J, Yki-Järvinen H, Vespasiani-Gentilucci U, Tavaglione F, Maurotti S, Bianco C, Di Maria G, Enea M, Fracanzani AL, Kärjä V, Lupo G, Männistö V, Meroni M, Piciotti R, Qadri S, Zito R, Craxì A, Di Marco V, Cammà C, Tripodo C, Valenti L, Romeo S, Petta S, Grimaudo S. PMID: 37088979.
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PubMed Mentions: Fields:
Translation:
Humans
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Fatty liver disease, heart rate and cardiac remodelling: Evidence from the UK Biobank. Liver Int. 2023 06; 43(6):1247-1255.
Jamialahmadi O, Tavaglione F, Rawshani A, Ljungman C, Romeo S. PMID: 36883784.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Effect of common genetic variants on the risk of cirrhosis in non-alcoholic fatty liver disease during 20 years of follow-up. Liver Int. 2022 12; 42(12):2769-2780.
Holmer M, Ekstedt M, Nasr P, Zenlander R, Wester A, Tavaglione F, Romeo S, Kechagias S, Stål P, Hagström H. PMID: 36166317; PMCID: PMC9828463.
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PubMed Mentions:
17 Fields:
Translation:
Humans
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Reply. Clin Gastroenterol Hepatol. 2023 03; 21(3):856-857.
Tavaglione F, De Vincentis A, Jamialahmadi O, Vespasiani-Gentilucci U, Romeo S. PMID: 35835343.
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PubMed Mentions: Fields:
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Development and Validation of a Score for Fibrotic Nonalcoholic Steatohepatitis. Clin Gastroenterol Hepatol. 2023 06; 21(6):1523-1532.e1.
Tavaglione F, Jamialahmadi O, De Vincentis A, Qadri S, Mowlaei ME, Mancina RM, Ciociola E, Carotti S, Perrone G, Bruni V, Gallo IF, Tuccinardi D, Bianco C, Prati D, Manfrini S, Pozzilli P, Picardi A, Caricato M, Yki-Järvinen H, Valenti L, Vespasiani-Gentilucci U, Romeo S. PMID: 35421583.
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PubMed Mentions:
27 Fields:
Translation:
Humans
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Rare ATG7 genetic variants predispose patients to severe fatty liver disease. J Hepatol. 2022 09; 77(3):596-606.
Baselli GA, Jamialahmadi O, Pelusi S, Ciociola E, Malvestiti F, Saracino M, Santoro L, Cherubini A, Dongiovanni P, Maggioni M, Bianco C, Tavaglione F, Cespiati A, Mancina RM, D'Ambrosio R, Vaira V, Petta S, Miele L, Vespasiani-Gentilucci U, Federico A, Pihlajamaki J, Bugianesi E, Fracanzani AL, Reeves HL, Soardo G, Prati D, Romeo S, Valenti LV, EPIDEMIC Study Investigators. PMID: 35405176.
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PubMed Mentions:
35 Fields:
Translation:
Humans
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A Genetic and Metabolic Staging System for Predicting the Outcome of Nonalcoholic Fatty Liver Disease. Hepatol Commun. 2022 05; 6(5):1032-1044.
Pennisi G, Pipitone RM, Enea M, De Vincentis A, Battaglia S, Di Marco V, Di Martino V, Spatola F, Tavaglione F, Vespasiani-Gentilucci U, Zito R, Romeo S, Cammà C, Craxì A, Grimaudo S, Petta S. PMID: 35146945; PMCID: PMC9035577.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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PSD3 downregulation confers protection against fatty liver disease. Nat Metab. 2022 01; 4(1):60-75.
Mancina RM, Sasidharan K, Lindblom A, Wei Y, Ciociola E, Jamialahmadi O, Pingitore P, Andréasson AC, Pellegrini G, Baselli G, Männistö V, Pihlajamäki J, Kärjä V, Grimaudo S, Marini I, Maggioni M, Becattini B, Tavaglione F, Dix C, Castaldo M, Klein S, Perelis M, Pattou F, Thuillier D, Raverdy V, Dongiovanni P, Fracanzani AL, Stickel F, Hampe J, Buch S, Luukkonen PK, Prati D, Yki-Järvinen H, Petta S, Xing C, Schafmayer C, Aigner E, Datz C, Lee RG, Valenti L, Lindén D, Romeo S. PMID: 35102341; PMCID: PMC8803605.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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Reply. Clin Gastroenterol Hepatol. 2022 11; 20(11):2660-2661.
De Vincentis A, Tavaglione F, Romeo S, Vespasiani-Gentilucci U. PMID: 35032632.
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PubMed Mentions: Fields:
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Accuracy of controlled attenuation parameter for assessing liver steatosis in individuals with morbid obesity before bariatric surgery. Liver Int. 2022 02; 42(2):374-383.
Tavaglione F, De Vincentis A, Bruni V, Gallo IF, Carotti S, Tuccinardi D, Spagnolo G, Ciociola E, Mancina RM, Jamialahmadi O, D'Alessio R, Bottazzi B, Manfrini S, Picardi A, Perrone G, Pozzilli P, Caricato M, Vespasiani-Gentilucci U, Romeo S. PMID: 34890093.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Metabolic and genetic determinants for progression to severe liver disease in subjects with obesity from the UK Biobank. Int J Obes (Lond). 2022 03; 46(3):486-493.
De Vincentis A, Tavaglione F, Spagnuolo R, Pujia R, Tuccinardi D, Mascianà G, Picardi A, Antonelli Incalzi R, Valenti L, Romeo S, Vespasiani-Gentilucci U. PMID: 34750514; PMCID: PMC8573310.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Genetic risk scores and personalization of care in fatty liver disease. Curr Opin Pharmacol. 2021 12; 61:6-11.
Bianco C, Tavaglione F, Romeo S, Valenti L. PMID: 34537584.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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A Polygenic Risk Score to Refine Risk Stratification and Prediction for Severe Liver Disease by Clinical Fibrosis Scores. Clin Gastroenterol Hepatol. 2022 03; 20(3):658-673.
De Vincentis A, Tavaglione F, Jamialahmadi O, Picardi A, Antonelli Incalzi R, Valenti L, Romeo S, Vespasiani-Gentilucci U. PMID: 34091049.
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PubMed Mentions:
47 Fields:
Translation:
Humans
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Inborn and acquired risk factors for severe liver disease in Europeans with type 2 diabetes from the UK Biobank. JHEP Rep. 2021 Jun; 3(3):100262.
Tavaglione F, De Vincentis A, Jamialahmadi O, Pujia R, Spagnuolo R, Picardi A, Morano S, Valenti L, Romeo S, Vespasiani-Gentilucci U. PMID: 33997749; PMCID: PMC8099786.
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PubMed Mentions:
10
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Understanding the underlying molecular pathways by which Mboat7/Lpiat1 depletion induces hepatic steatosis. J Lipid Res. 2021; 62:100047.
Tavaglione F, Kono N, Romeo S. PMID: 33582144; PMCID: PMC7985689.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimals
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Exome-Wide Association Study on Alanine Aminotransferase Identifies Sequence Variants in the GPAM and APOE Associated With Fatty Liver Disease. Gastroenterology. 2021 04; 160(5):1634-1646.e7.
Jamialahmadi O, Mancina RM, Ciociola E, Tavaglione F, Luukkonen PK, Baselli G, Malvestiti F, Thuillier D, Raverdy V, Männistö V, Pipitone RM, Pennisi G, Prati D, Spagnuolo R, Petta S, Pihlajamäki J, Pattou F, Yki-Järvinen H, Valenti L, Romeo S. PMID: 33347879.
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PubMed Mentions:
58 Fields:
Translation:
HumansCells
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Human and molecular genetics shed lights on fatty liver disease and diabetes conundrum. Endocrinol Diabetes Metab. 2020 Oct; 3(4):e00179.
Tavaglione F, Targher G, Valenti L, Romeo S. PMID: 33102799; PMCID: PMC7576307.
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PubMed Mentions:
7 Fields:
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Genetic variants in the MTHFR are not associated with fatty liver disease. Liver Int. 2020 08; 40(8):1934-1940.
De Vincentis A, Mancina RM, Pihlajamäki J, Männistö V, Petta S, Dongiovanni P, Fracanzani AL, Valenti L, Tavaglione F, Romeo S, Vespasiani-Gentilucci U. PMID: 32460399.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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PCSK9 Inhibitors in a Statin-Intolerant Transgender Man With Heterozygous Familial Hypercholesterolemia: A Case Report. J Endocr Soc. 2019 Aug 01; 3(8):1461-1464.
Pirazzi C, Tavaglione F, Tivesten Å, Romeo S. PMID: 31380502; PMCID: PMC6665951.
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