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Eugenio Santelli

TitleAssistant Project Scientist
InstitutionUniversity of California San Diego
DepartmentMedicine
Address9500 Gilman Drive #0656
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Sacchetti C, Bai Y, Stanford SM, Di Benedetto P, Cipriani P, Santelli E, Piera-Velazquez S, Chernitskiy V, Kiosses WB, Ceponis A, Kaestner KH, Boin F, Jimenez SA, Giacomelli R, Zhang ZY, Bottini N. PTP4A1 promotes TGFß signaling and fibrosis in systemic sclerosis. Nat Commun. 2017 10 20; 8(1):1060. PMID: 29057934.
      View in: PubMed
    2. Fabre L, Santelli E, Mountassif D, Donoghue A, Biswas A, Blunck R, Hanein D, Volkmann N, Liddington R, Rouiller I. Structure of anthrax lethal toxin prepore complex suggests a pathway for efficient cell entry. J Gen Physiol. 2016 Oct; 148(4):313-24. PMID: 27670897; PMCID: PMC5037343 [Available on 04/01/17].
    3. Stebbins JL, Santelli E, Feng Y, De SK, Purves A, Motamedchaboki K, Wu B, Ronai ZA, Liddington RC, Pellecchia M. Structure-based design of covalent Siah inhibitors. Chem Biol. 2013 Aug 22; 20(8):973-82. PMID: 23891150; PMCID: PMC3763817.
    4. Stranzl GR, Santelli E, Bankston LA, La Clair C, Bobkov A, Schwarzenbacher R, Godzik A, Perego M, Grynberg M, Liddington RC. Structural insights into inhibition of Bacillus anthracis sporulation by a novel class of non-heme globin sensor domains. J Biol Chem. 2011 Mar 11; 286(10):8448-58. PMID: 21216948; PMCID: PMC3048729.
    5. Delogu LG, Stanford SM, Santelli E, Magrini A, Bergamaschi A, Motamedchaboki K, Rosato N, Mustelin T, Bottini N, Bottini M. Carbon nanotube-based nanocarriers: the importance of keeping it clean. J Nanosci Nanotechnol. 2010 Aug; 10(8):5293-301. PMID: 21125885.
      View in: PubMed
    6. Chan SL, Mukasa T, Santelli E, Low LY, Pascual J. The crystal structure of a TIR domain from Arabidopsis thaliana reveals a conserved helical region unique to plants. Protein Sci. 2010 Jan; 19(1):155-61. PMID: 19845004; PMCID: PMC2817850.
    7. Chan SL, Low LY, Hsu S, Li S, Liu T, Santelli E, Le Negrate G, Reed JC, Woods VL, Pascual J. Molecular mimicry in innate immunity: crystal structure of a bacterial TIR domain. J Biol Chem. 2009 Aug 07; 284(32):21386-92. PMID: 19535337; PMCID: PMC2755863.
    8. Sui J, Hwang WC, Perez S, Wei G, Aird D, Chen LM, Santelli E, Stec B, Cadwell G, Ali M, Wan H, Murakami A, Yammanuru A, Han T, Cox NJ, Bankston LA, Donis RO, Liddington RC, Marasco WA. Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses. Nat Struct Mol Biol. 2009 Mar; 16(3):265-73. PMID: 19234466; PMCID: PMC2692245.
    9. Reixach N, Foss TR, Santelli E, Pascual J, Kelly JW, Buxbaum JN. Human-murine transthyretin heterotetramers are kinetically stable and non-amyloidogenic. A lesson in the generation of transgenic models of diseases involving oligomeric proteins. J Biol Chem. 2008 Jan 25; 283(4):2098-107. PMID: 18006495.
      View in: PubMed
    10. Kolla RV, Chintalapati S, Sabet M, Santelli E, Liddington RC, David M, Fierer J, Guiney D, Rickert RC. Complement C3d conjugation to anthrax protective antigen promotes a rapid, sustained, and protective antibody response. PLoS One. 2007 Oct 17; 2(10):e1044. PMID: 17940608; PMCID: PMC2001179.
    11. Mukasa T, Santelli E, Reed JC, Pascual J. Preliminary structural studies on the leucine-zipper homology region of the human protein Bap31. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Apr 01; 63(Pt 4):297-9. PMID: 17401199; PMCID: PMC2330218.
    12. Santelli E, Liddington RC, Mohan MA, Hoch JA, Szurmant H. The crystal structure of Bacillus subtilis YycI reveals a common fold for two members of an unusual class of sensor histidine kinase regulatory proteins. J Bacteriol. 2007 Apr; 189(8):3290-5. PMID: 17307848; PMCID: PMC1855859.
    13. Hwang WC, Lin Y, Santelli E, Sui J, Jaroszewski L, Stec B, Farzan M, Marasco WA, Liddington RC. Structural basis of neutralization by a human anti-severe acute respiratory syndrome spike protein antibody, 80R. J Biol Chem. 2006 Nov 10; 281(45):34610-6. PMID: 16954221.
      View in: PubMed
    14. Santelli E, Leone M, Li C, Fukushima T, Preece NE, Olson AJ, Ely KR, Reed JC, Pellecchia M, Liddington RC, Matsuzawa S. Structural analysis of Siah1-Siah-interacting protein interactions and insights into the assembly of an E3 ligase multiprotein complex. J Biol Chem. 2005 Oct 07; 280(40):34278-87. PMID: 16085652.
      View in: PubMed
    15. de Pereda JM, Wegener KL, Santelli E, Bate N, Ginsberg MH, Critchley DR, Campbell ID, Liddington RC. Structural basis for phosphatidylinositol phosphate kinase type Igamma binding to talin at focal adhesions. J Biol Chem. 2005 Mar 04; 280(9):8381-6. PMID: 15623515.
      View in: PubMed
    16. Santelli E, Bankston LA, Leppla SH, Liddington RC. Crystal structure of a complex between anthrax toxin and its host cell receptor. Nature. 2004 Aug 19; 430(7002):905-8. PMID: 15243628.
      View in: PubMed
    17. Santelli E, Schwarzenbacher R, McMullan D, Biorac T, Brinen LS, Canaves JM, Cambell J, Dai X, Deacon AM, Elsliger MA, Eshagi S, Floyd R, Godzik A, Grittini C, Grzechnik SK, Jaroszewski L, Karlak C, Klock HE, Koesema E, Kovarik JS, Kreusch A, Kuhn P, Lesley SA, McPhillips TM, Miller MD, Morse A, Moy K, Ouyang J, Page R, Quijano K, Rezezadeh F, Robb A, Sims E, Spraggon G, Stevens RC, van den Bedem H, Velasquez J, Vincent J, von Delft F, Wang X, West B, Wolf G, Xu Q, Hodgson KO, Wooley J, Wilson IA. Crystal structure of a glycerophosphodiester phosphodiesterase (GDPD) from Thermotoga maritima (TM1621) at 1.60 A resolution. Proteins. 2004 Jul 01; 56(1):167-70. PMID: 15162496.
      View in: PubMed
    18. Berger I, Bieniossek C, Schaffitzel C, Hassler M, Santelli E, Richmond TJ. Direct interaction of Ca2+/calmodulin inhibits histone deacetylase 5 repressor core binding to myocyte enhancer factor 2. J Biol Chem. 2003 May 16; 278(20):17625-35. PMID: 12626519.
      View in: PubMed
    19. Santelli E, Richmond TJ. Crystal structure of MEF2A core bound to DNA at 1.5 A resolution. J Mol Biol. 2000 Mar 24; 297(2):437-49. PMID: 10715212.
      View in: PubMed