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Eugenio Santelli

Title(s)Assistant Project Scientist, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #0656
La Jolla CA 92093
Phone000-000-NULL
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal. Sci Adv. 2020 Jun; 6(26):eaba4353. Svensson MND, Zoccheddu M, Yang S, Nygaard G, Secchi C, Doody KM, Slowikowski K, Mizoguchi F, Humby F, Hands R, Santelli E, Sacchetti C, Wakabayashi K, Wu DJ, Barback C, Ai R, Wang W, Sims GP, Mydel P, Kasama T, Boyle DL, Galimi F, Vera D, Tremblay ML, Raychaudhuri S, Brenner MB, Firestein GS, Pitzalis C, Ekwall AH, Stanford SM, Bottini N. PMID: 32637608.
      View in: PubMed   Mentions:    Fields:    
    2. PTPN22 phosphorylation acts as a molecular rheostat for the inhibition of TCR signaling. Sci Signal. 2020 Mar 17; 13(623). Yang S, Svensson MND, Harder NHO, Hsieh WC, Santelli E, Kiosses WB, Moresco JJ, Yates JR, King CC, Liu L, Stanford SM, Bottini N. PMID: 32184287.
      View in: PubMed   Mentions:    Fields:    
    3. RPTPa phosphatase activity is allosterically regulated by the membrane-distal catalytic domain. J Biol Chem. 2020 Apr 10; 295(15):4923-4936. Wen Y, Yang S, Wakabayashi K, Svensson MND, Stanford SM, Santelli E, Bottini N. PMID: 32139509.
      View in: PubMed   Mentions: 1     Fields:    
    4. Reduced expression of phosphatase PTPN2 promotes pathogenic conversion of Tregs in autoimmunity. J Clin Invest. 2019 03 01; 129(3):1193-1210. Svensson MN, Doody KM, Schmiedel BJ, Bhattacharyya S, Panwar B, Wiede F, Yang S, Santelli E, Wu DJ, Sacchetti C, Gujar R, Seumois G, Kiosses WB, Aubry I, Kim G, Mydel P, Sakaguchi S, Kronenberg M, Tiganis T, Tremblay ML, Ay F, Vijayanand P, Bottini N. PMID: 30620725.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    5. PTP4A1 promotes TGFß signaling and fibrosis in systemic sclerosis. Nat Commun. 2017 10 20; 8(1):1060. Sacchetti C, Bai Y, Stanford SM, Di Benedetto P, Cipriani P, Santelli E, Piera-Velazquez S, Chernitskiy V, Kiosses WB, Ceponis A, Kaestner KH, Boin F, Jimenez SA, Giacomelli R, Zhang ZY, Bottini N. PMID: 29057934.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    6. Structure of anthrax lethal toxin prepore complex suggests a pathway for efficient cell entry. J Gen Physiol. 2016 10; 148(4):313-24. Fabre L, Santelli E, Mountassif D, Donoghue A, Biswas A, Blunck R, Hanein D, Volkmann N, Liddington R, Rouiller I. PMID: 27670897.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    7. Structure-based design of covalent Siah inhibitors. Chem Biol. 2013 Aug 22; 20(8):973-82. Stebbins JL, Santelli E, Feng Y, De SK, Purves A, Motamedchaboki K, Wu B, Ronai ZA, Liddington RC, Pellecchia M. PMID: 23891150.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    8. Structural insights into inhibition of Bacillus anthracis sporulation by a novel class of non-heme globin sensor domains. J Biol Chem. 2011 Mar 11; 286(10):8448-58. Stranzl GR, Santelli E, Bankston LA, La Clair C, Bobkov A, Schwarzenbacher R, Godzik A, Perego M, Grynberg M, Liddington RC. PMID: 21216948.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    9. Carbon nanotube-based nanocarriers: the importance of keeping it clean. J Nanosci Nanotechnol. 2010 Aug; 10(8):5293-301. Delogu LG, Stanford SM, Santelli E, Magrini A, Bergamaschi A, Motamedchaboki K, Rosato N, Mustelin T, Bottini N, Bottini M. PMID: 21125885.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCellsPHPublic Health
    10. The crystal structure of a TIR domain from Arabidopsis thaliana reveals a conserved helical region unique to plants. Protein Sci. 2010 Jan; 19(1):155-61. Chan SL, Mukasa T, Santelli E, Low LY, Pascual J. PMID: 19845004.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    11. Molecular mimicry in innate immunity: crystal structure of a bacterial TIR domain. J Biol Chem. 2009 Aug 07; 284(32):21386-92. Chan SL, Low LY, Hsu S, Li S, Liu T, Santelli E, Le Negrate G, Reed JC, Woods VL, Pascual J. PMID: 19535337.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    12. Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses. Nat Struct Mol Biol. 2009 Mar; 16(3):265-73. Sui J, Hwang WC, Perez S, Wei G, Aird D, Chen LM, Santelli E, Stec B, Cadwell G, Ali M, Wan H, Murakami A, Yammanuru A, Han T, Cox NJ, Bankston LA, Donis RO, Liddington RC, Marasco WA. PMID: 19234466.
      View in: PubMed   Mentions: 505     Fields:    Translation:HumansAnimalsCells
    13. Human-murine transthyretin heterotetramers are kinetically stable and non-amyloidogenic. A lesson in the generation of transgenic models of diseases involving oligomeric proteins. J Biol Chem. 2008 Jan 25; 283(4):2098-107. Reixach N, Foss TR, Santelli E, Pascual J, Kelly JW, Buxbaum JN. PMID: 18006495.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    14. Complement C3d conjugation to anthrax protective antigen promotes a rapid, sustained, and protective antibody response. PLoS One. 2007 Oct 17; 2(10):e1044. Kolla RV, Chintalapati S, Sabet M, Santelli E, Liddington RC, David M, Fierer J, Guiney D, Rickert RC. PMID: 17940608.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    15. Preliminary structural studies on the leucine-zipper homology region of the human protein Bap31. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Apr 01; 63(Pt 4):297-9. Mukasa T, Santelli E, Reed JC, Pascual J. PMID: 17401199.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    16. The crystal structure of Bacillus subtilis YycI reveals a common fold for two members of an unusual class of sensor histidine kinase regulatory proteins. J Bacteriol. 2007 Apr; 189(8):3290-5. Santelli E, Liddington RC, Mohan MA, Hoch JA, Szurmant H. PMID: 17307848.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    17. Structural basis of neutralization by a human anti-severe acute respiratory syndrome spike protein antibody, 80R. J Biol Chem. 2006 Nov 10; 281(45):34610-6. Hwang WC, Lin Y, Santelli E, Sui J, Jaroszewski L, Stec B, Farzan M, Marasco WA, Liddington RC. PMID: 16954221.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    18. Structural analysis of Siah1-Siah-interacting protein interactions and insights into the assembly of an E3 ligase multiprotein complex. J Biol Chem. 2005 Oct 07; 280(40):34278-87. Santelli E, Leone M, Li C, Fukushima T, Preece NE, Olson AJ, Ely KR, Reed JC, Pellecchia M, Liddington RC, Matsuzawa S. PMID: 16085652.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    19. Structural basis for phosphatidylinositol phosphate kinase type Igamma binding to talin at focal adhesions. J Biol Chem. 2005 Mar 04; 280(9):8381-6. de Pereda JM, Wegener KL, Santelli E, Bate N, Ginsberg MH, Critchley DR, Campbell ID, Liddington RC. PMID: 15623515.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    20. Crystal structure of a complex between anthrax toxin and its host cell receptor. Nature. 2004 Aug 19; 430(7002):905-8. Santelli E, Bankston LA, Leppla SH, Liddington RC. PMID: 15243628.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansCells
    21. Crystal structure of a glycerophosphodiester phosphodiesterase (GDPD) from Thermotoga maritima (TM1621) at 1.60 A resolution. Proteins. 2004 Jul 01; 56(1):167-70. Santelli E, Schwarzenbacher R, McMullan D, Biorac T, Brinen LS, Canaves JM, Cambell J, Dai X, Deacon AM, Elsliger MA, Eshagi S, Floyd R, Godzik A, Grittini C, Grzechnik SK, Jaroszewski L, Karlak C, Klock HE, Koesema E, Kovarik JS, Kreusch A, Kuhn P, Lesley SA, McPhillips TM, Miller MD, Morse A, Moy K, Ouyang J, Page R, Quijano K, Rezezadeh F, Robb A, Sims E, Spraggon G, Stevens RC, van den Bedem H, Velasquez J, Vincent J, von Delft F, Wang X, West B, Wolf G, Xu Q, Hodgson KO, Wooley J, Wilson IA. PMID: 15162496.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    22. Direct interaction of Ca2+/calmodulin inhibits histone deacetylase 5 repressor core binding to myocyte enhancer factor 2. J Biol Chem. 2003 May 16; 278(20):17625-35. Berger I, Bieniossek C, Schaffitzel C, Hassler M, Santelli E, Richmond TJ. PMID: 12626519.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    23. Crystal structure of MEF2A core bound to DNA at 1.5 A resolution. J Mol Biol. 2000 Mar 24; 297(2):437-49. Santelli E, Richmond TJ. PMID: 10715212.
      View in: PubMed   Mentions: 39     Fields:    Translation:Cells
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