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Eric Esteve

TitleVisiting Associate Professor
InstitutionUniversity of California San Diego
DepartmentMedicine
Address9500 Gilman Drive #0613
La Jolla CA 92093
Emaileesteve@ucsd.edu
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    Collapse Biography 
    Collapse Education and Training
    University of Mediterranean, France PhD02/2004Biology
    UNiversity of Grenoble Alps, France Associate ProfessorpresentBiology
    Collapse Awards and Honors
    University of Grenoble alps2018  - presAssociate Professor
    UCSD2018  - presvisiting professor
    University of Grenoble Alps2010  - 2018Assistant professor

    Collapse Overview 
    Collapse Overview
    Calcium signaling in skeletal and cardiac muscles. Ryanodine receptor, SERCA and sarcoplasmic reticulum are part of my everyday-experiments. Myopathies (DMD, DCM) are the diseases I am interested in.


    Collapse Research 
    Collapse Research Activities and Funding
    whole body periodic acceleration a novel treatment for duchenne cardiomyopathy in mdx mice
    AFM-Telethon (French association against Myopathies) Jan 9, 2018 - Aug 31, 2020
    Role: co-PI
    Role Description: Calcium imaging, physical training, design experiments, writer

    Collapse ORNG Applications 
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Dabouz F, Khemis A, Barbe C, Lahfa M, Maccari F, Chaby G, Beneton N, Boye T, Esteve E, Mahé E, Begon E, Pauwels C, Bernard P, Taieb C, Reguiai Z. Factors associated with successful switching between biologic therapies for the treatment of psoriasis in daily dermatological real-life practice: The Resoswitch study. Dermatol Ther. 2018 Nov 28; e12789. PMID: 30488520.
      View in: PubMed
    2. Esteve E, Maccari F, Delavierre D, Vicariot C, Charles B, Marty M, Lespessailles E. Preliminary development of a questionnaire assessing the impact of psoriasis and psoriatic arthritis on patient's perception of sexuality. Medicine (Baltimore). 2018 Oct; 97(42):e12807. PMID: 30334975.
      View in: PubMed
    3. Lopez JR, Uryash A, Kolster J, Estève E, Zhang R, Adams JA. Enhancing Endogenous Nitric Oxide by Whole Body Periodic Acceleration Elicits Neuroprotective Effects in Dystrophic Neurons. Mol Neurobiol. 2018 Nov; 55(11):8680-8694. PMID: 29582400.
      View in: PubMed
    4. Coquand-Gandit M, Jacob MP, Fhayli W, Romero B, Georgieva M, Bouillot S, Estève E, Andrieu JP, Brasseur S, Bouyon S, Garcia-Honduvilla N, Huber P, Buján J, Atanasova M, Faury G. Chronic Treatment with Minoxidil Induces Elastic Fiber Neosynthesis and Functional Improvement in the Aorta of Aged Mice. Rejuvenation Res. 2017 Jun; 20(3):218-230. PMID: 28056723.
      View in: PubMed
    5. Lopez JR, Kolster J, Uryash A, Estève E, Altamirano F, Adams JA. Dysregulation of Intracellular Ca2+ in Dystrophic Cortical and Hippocampal Neurons. Mol Neurobiol. 2018 01; 55(1):603-618. PMID: 27975174.
      View in: PubMed
    6. Dahan D, Ducret T, Quignard JF, Marthan R, Savineau JP, Estève E. Implication of the ryanodine receptor in TRPV4-induced calcium response in pulmonary arterial smooth muscle cells from normoxic and chronically hypoxic rats. Am J Physiol Lung Cell Mol Physiol. 2012 Nov 01; 303(9):L824-33. PMID: 22962011.
      View in: PubMed
    7. Estève E, Eltit JM, Bannister RA, Liu K, Pessah IN, Beam KG, Allen PD, López JR. A malignant hyperthermia-inducing mutation in RYR1 (R163C): alterations in Ca2+ entry, release, and retrograde signaling to the DHPR. J Gen Physiol. 2010 Jun; 135(6):619-28. PMID: 20479110; PMCID: PMC2888056.
    8. Bannister RA, Estève E, Eltit JM, Pessah IN, Allen PD, López JR, Beam KG. A malignant hyperthermia-inducing mutation in RYR1 (R163C): consequent alterations in the functional properties of DHPR channels. J Gen Physiol. 2010 Jun; 135(6):629-40. PMID: 20479108; PMCID: PMC2888063.
    9. Yang T, Esteve E, Pessah IN, Molinski TF, Allen PD, López JR. Elevated resting [Ca(2+)](i) in myotubes expressing malignant hyperthermia RyR1 cDNAs is partially restored by modulation of passive calcium leak from the SR. Am J Physiol Cell Physiol. 2007 May; 292(5):C1591-8. PMID: 17182726.
      View in: PubMed
    10. Yang T, Riehl J, Esteve E, Matthaei KI, Goth S, Allen PD, Pessah IN, Lopez JR. Pharmacologic and functional characterization of malignant hyperthermia in the R163C RyR1 knock-in mouse. Anesthesiology. 2006 Dec; 105(6):1164-75. PMID: 17122579.
      View in: PubMed
    11. Estève E, Mabrouk K, Dupuis A, Smida-Rezgui S, Altafaj X, Grunwald D, Platel JC, Andreotti N, Marty I, Sabatier JM, Ronjat M, De Waard M. Transduction of the scorpion toxin maurocalcine into cells. Evidence that the toxin crosses the plasma membrane. J Biol Chem. 2005 Apr 01; 280(13):12833-9. PMID: 15653689.
      View in: PubMed
    12. Altafaj X, Cheng W, Estève E, Urbani J, Grunwald D, Sabatier JM, Coronado R, De Waard M, Ronjat M. Maurocalcine and domain A of the II-III loop of the dihydropyridine receptor Cav 1.1 subunit share common binding sites on the skeletal ryanodine receptor. J Biol Chem. 2005 Feb 11; 280(6):4013-6. PMID: 15591063.
      View in: PubMed
    13. Estève E, Smida-Rezgui S, Sarkozi S, Szegedi C, Regaya I, Chen L, Altafaj X, Rochat H, Allen P, Pessah IN, Marty I, Sabatier JM, Jona I, De Waard M, Ronjat M. Critical amino acid residues determine the binding affinity and the Ca2+ release efficacy of maurocalcine in skeletal muscle cells. J Biol Chem. 2003 Sep 26; 278(39):37822-31. PMID: 12869557.
      View in: PubMed
    14. Chen L, Estève E, Sabatier JM, Ronjat M, De Waard M, Allen PD, Pessah IN. Maurocalcine and peptide A stabilize distinct subconductance states of ryanodine receptor type 1, revealing a proportional gating mechanism. J Biol Chem. 2003 May 02; 278(18):16095-106. PMID: 12586831.
      View in: PubMed
    15. di Luccio E, Matavel A, Opi S, Regaya I, Sandoz G, M'barek S, Carlier E, Estève E, Carrega L, Fajloun Z, Rochat H, Loret E, de Waard M, Sabatier JM. Evolution of maurotoxin conformation and blocking efficacy towards Shaker B channels during the course of folding and oxidation in vitro. Biochem J. 2002 Jan 15; 361(Pt 2):409-16. PMID: 11772414.
      View in: PubMed
    16. di Luccio E, Azulay DO, Regaya I, Fajloun Z, Sandoz G, Mansuelle P, Kharrat R, Fathallah M, Carrega L, Estève E, Rochat H, De Waard M, Sabatier JM. Parameters affecting in vitro oxidation/folding of maurotoxin, a four-disulphide-bridged scorpion toxin. Biochem J. 2001 Sep 15; 358(Pt 3):681-92. PMID: 11535129.
      View in: PubMed
    17. Grélot L, Dapzol J, Estève E, Frugière A, Bianchi AL, Sheldrick RL, Gardner CJ, Ward P. Potent inhibition of both the acute and delayed emetic responses to cisplatin in piglets treated with GR205171, a novel highly selective tachykinin NK1 receptor antagonist. Br J Pharmacol. 1998 Aug; 124(8):1643-50. PMID: 9756379.
      View in: PubMed
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