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Elizabeth Bowles

TitleClinical Nurse
InstitutionUniversity of California San Diego
DepartmentEmergency Medicine
Address200 W. Arbor Drive #8665
San Diego CA 92103
Phone619-543-6400
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Bowles E, Feys D, Ercal N, Sprague RS. Liposomal-delivery of phosphodiesterase 5 inhibitors augments UT-15C-stimulated ATP release from human erythrocytes. Biochem Biophys Rep. 2017 Dec; 12:114-119. PMID: 28955799.
      View in: PubMed
    2. Dergunov SA, Bowles E, Gordon W, Green M, Bierman A, Ellsworth ML, Pinkhassik E, Sprague RS. Liposomal delivery of a phosphodiesterase 3 inhibitor rescues low oxygen-induced ATP release from erythrocytes of humans with type 2 diabetes. Biochem Biophys Rep. 2015 Jul; 2:137-142. PMID: 29124155.
      View in: PubMed
    3. Liang X, Samways DS, Wolf K, Bowles E, Richards JP, Bruno J, Dutertre S, DiPaolo RJ, Egan TM. Quantifying Ca2+ current and permeability in ATP-gated P2X7 receptors. J Biol Chem. 2015 Mar 20; 290(12):7930-42. PMID: 25645917; PMCID: PMC4367291.
    4. Richards JP, Bowles E, Gordon WR, Ellsworth ML, Stephenson AH, Sprague RS. Mechanisms of C-peptide-mediated rescue of low O2-induced ATP release from erythrocytes of humans with type 2 diabetes. Am J Physiol Regul Integr Comp Physiol. 2015 Mar 01; 308(5):R411-8. PMID: 25552662.
      View in: PubMed
    5. Bowles E, Moody GN, Yeragunta Y, Stephenson AH, Ellsworth ML, Sprague RS. Phosphodiesterase 5 inhibitors augment UT-15C-stimulated ATP release from erythrocytes of humans with pulmonary arterial hypertension. Exp Biol Med (Maywood). 2015 Jan; 240(1):121-7. PMID: 25125498.
      View in: PubMed
    6. Knebel SM, Elrick MM, Bowles E, Zdanovec AK, Stephenson AH, Ellsworth ML, Sprague RS. Synergistic effects of prostacyclin analogs and phosphodiesterase inhibitors on cyclic adenosine 3',5' monophosphate accumulation and adenosine 3'5' triphosphate release from human erythrocytes. Exp Biol Med (Maywood). 2013 Sep; 238(9):1069-74. PMID: 23986226.
      View in: PubMed
    7. Sridharan M, Bowles E, Richards JP, Krantic M, Davis KL, Dietrich KA, Stephenson AH, Ellsworth ML, Sprague RS. Prostacyclin receptor-mediated ATP release from erythrocytes requires the voltage-dependent anion channel. Am J Physiol Heart Circ Physiol. 2012 Feb 01; 302(3):H553-9. PMID: 22159995; PMCID: PMC3353798.
    8. Sprague RS, Bowles E, Achilleus D, Stephenson AH, Ellis CG, Ellsworth ML. A selective phosphodiesterase 3 inhibitor rescues low PO2-induced ATP release from erythrocytes of humans with type 2 diabetes: implication for vascular control. Am J Physiol Heart Circ Physiol. 2011 Dec; 301(6):H2466-72. PMID: 21963837; PMCID: PMC3233804.
    9. Adderley SP, Thuet KM, Sridharan M, Bowles E, Stephenson AH, Ellsworth ML, Sprague RS. Identification of cytosolic phosphodiesterases in the erythrocyte: a possible role for PDE5. Med Sci Monit. 2011 May; 17(5):CR241-7. PMID: 21525805; PMCID: PMC3366467.
    10. Adderley SP, Sridharan M, Bowles E, Stephenson AH, Sprague RS, Ellsworth ML. Inhibition of ATP release from erythrocytes: a role for EPACs and PKC. Microcirculation. 2011 Feb; 18(2):128-35. PMID: 21166931; PMCID: PMC3034780.
    11. Sridharan M, Sprague RS, Adderley SP, Bowles E, Ellsworth ML, Stephenson AH. Diamide decreases deformability of rabbit erythrocytes and attenuates low oxygen tension-induced ATP release. Exp Biol Med (Maywood). 2010 Sep; 235(9):1142-8. PMID: 20682601; PMCID: PMC3138790.
    12. Sridharan M, Adderley SP, Bowles E, Egan TM, Stephenson AH, Ellsworth ML, Sprague RS. Pannexin 1 is the conduit for low oxygen tension-induced ATP release from human erythrocytes. Am J Physiol Heart Circ Physiol. 2010 Oct; 299(4):H1146-52. PMID: 20622111; PMCID: PMC2957350.
    13. Sprague RS, Goldman D, Bowles E, Achilleus D, Stephenson AH, Ellis CG, Ellsworth ML. Divergent effects of low-O(2) tension and iloprost on ATP release from erythrocytes of humans with type 2 diabetes: implications for O(2) supply to skeletal muscle. Am J Physiol Heart Circ Physiol. 2010 Aug; 299(2):H566-73. PMID: 20511412; PMCID: PMC2930397.
    14. Hanson MS, Stephenson AH, Bowles E, Sprague RS. Insulin inhibits human erythrocyte cAMP accumulation and ATP release: role of phosphodiesterase 3 and phosphoinositide 3-kinase. Exp Biol Med (Maywood). 2010 Feb; 235(2):256-62. PMID: 20404042; PMCID: PMC2892266.
    15. Adderley SP, Sridharan M, Bowles E, Stephenson AH, Ellsworth ML, Sprague RS. Protein kinases A and C regulate receptor-mediated increases in cAMP in rabbit erythrocytes. Am J Physiol Heart Circ Physiol. 2010 Feb; 298(2):H587-93. PMID: 20008267; PMCID: PMC2822589.
    16. Hanson MS, Ellsworth ML, Achilleus D, Stephenson AH, Bowles E, Sridharan M, Adderley S, Sprague RS. Insulin inhibits low oxygen-induced ATP release from human erythrocytes: implication for vascular control. Microcirculation. 2009 Jul; 16(5):424-33. PMID: 19412833; PMCID: PMC2906128.
    17. Adderley SP, Dufaux EA, Sridharan M, Bowles E, Hanson MS, Stephenson AH, Ellsworth ML, Sprague RS. Iloprost- and isoproterenol-induced increases in cAMP are regulated by different phosphodiesterases in erythrocytes of both rabbits and humans. Am J Physiol Heart Circ Physiol. 2009 May; 296(5):H1617-24. PMID: 19252089; PMCID: PMC2685344.
    18. Sprague RS, Hanson MS, Achilleus D, Bowles E, Stephenson AH, Sridharan M, Adderley S, Procknow J, Ellsworth ML. Rabbit erythrocytes release ATP and dilate skeletal muscle arterioles in the presence of reduced oxygen tension. Pharmacol Rep. 2009 Jan-Feb; 61(1):183-90. PMID: 19307706.
      View in: PubMed
    19. Sprague RS, Bowles E, Hanson MS, DuFaux EA, Sridharan M, Adderley S, Ellsworth ML, Stephenson AH. Prostacyclin analogs stimulate receptor-mediated cAMP synthesis and ATP release from rabbit and human erythrocytes. Microcirculation. 2008 Jul; 15(5):461-71. PMID: 18574748; PMCID: PMC3076303.
    20. Hanson MS, Stephenson AH, Bowles E, Sridharan M, Adderley S, Sprague RS. Phosphodiesterase 3 is present in rabbit and human erythrocytes and its inhibition potentiates iloprost-induced increases in cAMP. Am J Physiol Heart Circ Physiol. 2008 Aug; 295(2):H786-93. PMID: 18586889; PMCID: PMC2519193.
    21. Sprague RS, Stephenson AH, Bowles E, Stumpf MS, Lonigro AJ. Reduced expression of G(i) in erythrocytes of humans with type 2 diabetes is associated with impairment of both cAMP generation and ATP release. Diabetes. 2006 Dec; 55(12):3588-93. PMID: 17130508.
      View in: PubMed
    22. Sprague R, Stephenson A, Bowles E, Stumpf M, Ricketts G, Lonigro A. Expression of the heterotrimeric G protein Gi and ATP release are impaired in erythrocytes of humans with diabetes mellitus. Adv Exp Med Biol. 2006; 588:207-16. PMID: 17089891.
      View in: PubMed
    23. Sprague R, Bowles E, Stumpf M, Ricketts G, Freidman A, Hou WH, Stephenson A, Lonigro A. Rabbit erythrocytes possess adenylyl cyclase type II that is activated by the heterotrimeric G proteins Gs and Gi. Pharmacol Rep. 2005; 57 Suppl:222-8. PMID: 16415502.
      View in: PubMed
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