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Elisabetta Mantuano

Title(s)ASSOC PROJ SCI-FY NON REP, Pathology
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A soluble derivative of PrPC activates cell-signaling and regulates cell physiology through LRP1 and the NMDA receptor. J Biol Chem. 2020 Oct 09; 295(41):14178-14188. Mantuano E, Azmoon P, Banki MA, Lam MS, Sigurdson CJ, Gonias SL. PMID: 32788217.
      View in: PubMed   Mentions:    Fields:    
    2. Fibrinolysis protease receptors promote activation of astrocytes to express pro-inflammatory cytokines. J Neuroinflammation. 2019 Dec 06; 16(1):257. Pontecorvi P, Banki MA, Zampieri C, Zalfa C, Azmoon P, Kounnas MZ, Marchese C, Gonias SL, Mantuano E. PMID: 31810478.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    3. Tissue-type plasminogen activator selectively inhibits multiple toll-like receptors in CSF-1-differentiated macrophages. PLoS One. 2019; 14(11):e0224738. Das L, Azmoon P, Banki MA, Mantuano E, Gonias SL. PMID: 31697716.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    4. A multimolecular signaling complex including PrPC and LRP1 is strictly dependent on lipid rafts and is essential for the function of tissue plasminogen activator. J Neurochem. 2020 02; 152(4):468-481. Mattei V, Manganelli V, Martellucci S, Capozzi A, Mantuano E, Longo A, Ferri A, Garofalo T, Sorice M, Misasi R. PMID: 31602645.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    5. Tissue-type plasminogen activator neutralizes LPS but not protease-activated receptor-mediated inflammatory responses to plasmin. J Leukoc Biol. 2019 04; 105(4):729-740. Zalfa C, Azmoon P, Mantuano E, Gonias SL. PMID: 30690783.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    6. PAI1 blocks NMDA receptor-mediated effects of tissue-type plasminogen activator on cell signaling and physiology. J Cell Sci. 2018 07 26; 131(14). Gonias SL, Banki MA, Gilder AS, Azmoon P, Campana WM, Mantuano E. PMID: 29930084.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    7. The Urokinase Receptor Induces a Mesenchymal Gene Expression Signature in Glioblastoma Cells and Promotes Tumor Cell Survival in Neurospheres. Sci Rep. 2018 02 14; 8(1):2982. Gilder AS, Natali L, Van Dyk DM, Zalfa C, Banki MA, Pizzo DP, Wang H, Klemke RL, Mantuano E, Gonias SL. PMID: 29445239.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    8. Expression of LDL receptor-related proteins (LRPs) in common solid malignancies correlates with patient survival. PLoS One. 2017; 12(10):e0186649. Gonias SL, Karimi-Mostowfi N, Murray SS, Mantuano E, Gilder AS. PMID: 29088295.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    9. Tissue-type plasminogen activator regulates macrophage activation and innate immunity. Blood. 2017 09 14; 130(11):1364-1374. Mantuano E, Azmoon P, Brifault C, Banki MA, Gilder AS, Campana WM, Gonias SL. PMID: 28684538.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    10. Ionotropic glutamate receptors activate cell signaling in response to glutamate in Schwann cells. FASEB J. 2017 04; 31(4):1744-1755. Campana WM, Mantuano E, Azmoon P, Henry K, Banki MA, Kim JH, Pizzo DP, Gonias SL. PMID: 28073836.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    11. Evidence that LDL receptor-related protein 1 acts as an early injury detection receptor and activates c-Jun in Schwann cells. Neuroreport. 2016 12 14; 27(18):1305-1311. Flütsch A, Henry K, Mantuano E, Lam MS, Shibayama M, Takahashi K, Gonias SL, Campana WM. PMID: 27824728.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    12. The activities of LDL Receptor-related Protein-1 (LRP1) compartmentalize into distinct plasma membrane microdomains. Mol Cell Neurosci. 2016 10; 76:42-51. Laudati E, Gilder AS, Lam MS, Misasi R, Sorice M, Gonias SL, Mantuano E. PMID: 27565578.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    13. LDL receptor-related protein-1 regulates NF?B and microRNA-155 in macrophages to control the inflammatory response. Proc Natl Acad Sci U S A. 2016 Feb 02; 113(5):1369-74. Mantuano E, Brifault C, Lam MS, Azmoon P, Gilder AS, Gonias SL. PMID: 26787872.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    14. The NMDA receptor functions independently and as an LRP1 co-receptor to promote Schwann cell survival and migration. J Cell Sci. 2015 Sep 15; 128(18):3478-88. Mantuano E, Lam MS, Shibayama M, Campana WM, Gonias SL. PMID: 26272917.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    15. Mammalian target of rapamycin complex 2 (mTORC2) is a critical determinant of bladder cancer invasion. PLoS One. 2013; 8(11):e81081. Gupta S, Hau AM, Beach JR, Harwalker J, Mantuano E, Gonias SL, Egelhoff TT, Hansel DE. PMID: 24312263.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    16. LRP1 assembles unique co-receptor systems to initiate cell signaling in response to tissue-type plasminogen activator and myelin-associated glycoprotein. J Biol Chem. 2013 Nov 22; 288(47):34009-34018. Mantuano E, Lam MS, Gonias SL. PMID: 24129569.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    17. Low-density lipoprotein receptor related protein-1 (LRP1)-dependent cell signaling promotes neurotrophic activity in embryonic sensory neurons. PLoS One. 2013; 8(9):e75497. Yamauchi K, Yamauchi T, Mantuano E, Murakami K, Henry K, Takahashi K, Campana WM. PMID: 24086544.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    18. Schwann cell LRP1 regulates remak bundle ultrastructure and axonal interactions to prevent neuropathic pain. J Neurosci. 2013 Mar 27; 33(13):5590-602. Orita S, Henry K, Mantuano E, Yamauchi K, De Corato A, Ishikawa T, Feltri ML, Wrabetz L, Gaultier A, Pollack M, Ellisman M, Takahashi K, Gonias SL, Campana WM. PMID: 23536074.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    19. LDL receptor-related protein-1 is a sialic-acid-independent receptor for myelin-associated glycoprotein that functions in neurite outgrowth inhibition by MAG and CNS myelin. J Cell Sci. 2013 Jan 01; 126(Pt 1):209-20. Stiles TL, Dickendesher TL, Gaultier A, Fernandez-Castaneda A, Mantuano E, Giger RJ, Gonias SL. PMID: 23132925.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    20. A new 4-phenyl-1,8-naphthyridine derivative affects carcinoma cell proliferation by impairing cell cycle progression and inducing apoptosis. Anticancer Agents Med Chem. 2012 Jul; 12(6):653-62. Capozzi A, Mantuano E, Matarrese P, Saccomanni G, Manera C, Mattei V, Gambardella L, Malorni W, Sorice M, Misasi R. PMID: 22263796.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    21. The unfolded protein response is a major mechanism by which LRP1 regulates Schwann cell survival after injury. J Neurosci. 2011 Sep 21; 31(38):13376-85. Mantuano E, Henry K, Yamauchi T, Hiramatsu N, Yamauchi K, Orita S, Takahashi K, Lin JH, Gonias SL, Campana WM. PMID: 21940431.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    22. Low density lipoprotein receptor-related protein (LRP1) regulates Rac1 and RhoA reciprocally to control Schwann cell adhesion and migration. J Biol Chem. 2010 May 07; 285(19):14259-66. Mantuano E, Jo M, Gonias SL, Campana WM. PMID: 20197276.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    23. Erythropoietin promotes Schwann cell migration and assembly of the provisional extracellular matrix by recruiting beta1 integrin to the cell surface. Glia. 2010 Mar; 58(4):399-409. Inoue G, Gaultier A, Li X, Mantuano E, Richardson G, Takahashi K, Campana WM. PMID: 19705458.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    24. Ligand binding to LRP1 transactivates Trk receptors by a Src family kinase-dependent pathway. Sci Signal. 2009 Apr 28; 2(68):ra18. Shi Y, Mantuano E, Inoue G, Campana WM, Gonias SL. PMID: 19401592.
      View in: PubMed   Mentions: 68     Fields:    Translation:AnimalsCells
    25. The hemopexin domain of matrix metalloproteinase-9 activates cell signaling and promotes migration of schwann cells by binding to low-density lipoprotein receptor-related protein. J Neurosci. 2008 Nov 05; 28(45):11571-82. Mantuano E, Inoue G, Li X, Takahashi K, Gaultier A, Gonias SL, Campana WM. PMID: 18987193.
      View in: PubMed   Mentions: 83     Fields:    Translation:AnimalsCells
    26. 17beta-Estradiol and soy phytochemicals selectively induce a type 2 polarization in mesenteric lymph nodes of ovariectomized rats. Menopause. 2008 Jul-Aug; 15(4 Pt 1):718-25. Gallo D, Battaglia A, Mantuano E, Travaglia D, De Stefano I, Buzzonetti A, Scambia G. PMID: 18520337.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    27. Soy phytochemicals decrease nonsmall cell lung cancer growth in female athymic mice. J Nutr. 2008 Jul; 138(7):1360-4. Gallo D, Zannoni GF, De Stefano I, Mosca M, Ferlini C, Mantuano E, Scambia G. PMID: 18567761.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    28. Molecular dissection of the human alpha2-macroglobulin subunit reveals domains with antagonistic activities in cell signaling. J Biol Chem. 2008 Jul 18; 283(29):19904-11. Mantuano E, Mukandala G, Li X, Campana WM, Gonias SL. PMID: 18499670.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    29. Effects of a phytoestrogen-containing soy extract on the growth-inhibitory activity of ICI 182 780 in an experimental model of estrogen-dependent breast cancer. Endocr Relat Cancer. 2007 Jun; 14(2):317-24. Gallo D, Mantuano E, Fabrizi M, Ferlini C, Mozzetti S, De Stefano I, Scambia G. PMID: 17639047.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    30. Benzoyl and/or benzyl substituted 1,2,3-triazoles as potassium channel activators. VIII. Eur J Med Chem. 2005 Jun; 40(6):521-8. Calderone V, Giorgi I, Livi O, Martinotti E, Mantuano E, Martelli A, Nardi A. PMID: 15922836.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
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