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Elisabetta Mantuano

TitleAssistant Project Scientist
InstitutionUniversity of California San Diego
DepartmentPathology
Address9500 Gilman Drive #0612
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Gonias SL, Banki MA, Gilder AS, Azmoon P, Campana WM, Mantuano E. PAI1 blocks effects of tissue-type plasminogen activator on cell-signaling and physiology mediated by the NMDA receptor. J Cell Sci. 2018 Jun 21. PMID: 29930084.
      View in: PubMed
    2. Gilder AS, Natali L, Van Dyk DM, Zalfa C, Banki MA, Pizzo DP, Wang H, Klemke RL, Mantuano E, Gonias SL. The Urokinase Receptor Induces a Mesenchymal Gene Expression Signature in Glioblastoma Cells and Promotes Tumor Cell Survival in Neurospheres. Sci Rep. 2018 Feb 14; 8(1):2982. PMID: 29445239.
      View in: PubMed
    3. Gonias SL, Karimi-Mostowfi N, Murray SS, Mantuano E, Gilder AS. Expression of LDL receptor-related proteins (LRPs) in common solid malignancies correlates with patient survival. PLoS One. 2017; 12(10):e0186649. PMID: 29088295.
      View in: PubMed
    4. Mantuano E, Azmoon P, Brifault C, Banki MA, Gilder AS, Campana WM, Gonias SL. Tissue-type plasminogen activator regulates macrophage activation and innate immunity. Blood. 2017 09 14; 130(11):1364-1374. PMID: 28684538.
      View in: PubMed
    5. Campana WM, Mantuano E, Azmoon P, Henry K, Banki MA, Kim JH, Pizzo DP, Gonias SL. Ionotropic glutamate receptors activate cell signaling in response to glutamate in Schwann cells. FASEB J. 2017 04; 31(4):1744-1755. PMID: 28073836.
      View in: PubMed
    6. Flütsch A, Henry K, Mantuano E, Lam MS, Shibayama M, Takahashi K, Gonias SL, Campana WM. Evidence that LDL receptor-related protein 1 acts as an early injury detection receptor and activates c-Jun in Schwann cells. Neuroreport. 2016 12 14; 27(18):1305-1311. PMID: 27824728.
      View in: PubMed
    7. Laudati E, Gilder AS, Lam MS, Misasi R, Sorice M, Gonias SL, Mantuano E. The activities of LDL Receptor-related Protein-1 (LRP1) compartmentalize into distinct plasma membrane microdomains. Mol Cell Neurosci. 2016 10; 76:42-51. PMID: 27565578.
      View in: PubMed
    8. Mantuano E, Brifault C, Lam MS, Azmoon P, Gilder AS, Gonias SL. LDL receptor-related protein-1 regulates NF?B and microRNA-155 in macrophages to control the inflammatory response. Proc Natl Acad Sci U S A. 2016 Feb 02; 113(5):1369-74. PMID: 26787872; PMCID: PMC4747752.
      View in: PubMed, PubMed Central
    9. Mantuano E, Lam MS, Shibayama M, Campana WM, Gonias SL. The NMDA receptor functions independently and as an LRP1 co-receptor to promote Schwann cell survival and migration. J Cell Sci. 2015 Sep 15; 128(18):3478-88. PMID: 26272917; PMCID: PMC4594737.
      View in: PubMed, PubMed Central
    10. Gupta S, Hau AM, Beach JR, Harwalker J, Mantuano E, Gonias SL, Egelhoff TT, Hansel DE. Mammalian target of rapamycin complex 2 (mTORC2) is a critical determinant of bladder cancer invasion. PLoS One. 2013; 8(11):e81081. PMID: 24312263; PMCID: PMC3842329.
      View in: PubMed, PubMed Central
    11. Mantuano E, Lam MS, Gonias SL. LRP1 assembles unique co-receptor systems to initiate cell signaling in response to tissue-type plasminogen activator and myelin-associated glycoprotein. J Biol Chem. 2013 Nov 22; 288(47):34009-18. PMID: 24129569; PMCID: PMC3837140.
      View in: PubMed, PubMed Central
    12. Yamauchi K, Yamauchi T, Mantuano E, Murakami K, Henry K, Takahashi K, Campana WM. Low-density lipoprotein receptor related protein-1 (LRP1)-dependent cell signaling promotes neurotrophic activity in embryonic sensory neurons. PLoS One. 2013; 8(9):e75497. PMID: 24086544; PMCID: PMC3781060.
      View in: PubMed, PubMed Central
    13. Orita S, Henry K, Mantuano E, Yamauchi K, De Corato A, Ishikawa T, Feltri ML, Wrabetz L, Gaultier A, Pollack M, Ellisman M, Takahashi K, Gonias SL, Campana WM. Schwann cell LRP1 regulates remak bundle ultrastructure and axonal interactions to prevent neuropathic pain. J Neurosci. 2013 Mar 27; 33(13):5590-602. PMID: 23536074; PMCID: PMC3837698.
      View in: PubMed, PubMed Central
    14. Stiles TL, Dickendesher TL, Gaultier A, Fernandez-Castaneda A, Mantuano E, Giger RJ, Gonias SL. LDL receptor-related protein-1 is a sialic-acid-independent receptor for myelin-associated glycoprotein that functions in neurite outgrowth inhibition by MAG and CNS myelin. J Cell Sci. 2013 Jan 01; 126(Pt 1):209-20. PMID: 23132925; PMCID: PMC3603516.
      View in: PubMed, PubMed Central
    15. Capozzi A, Mantuano E, Matarrese P, Saccomanni G, Manera C, Mattei V, Gambardella L, Malorni W, Sorice M, Misasi R. A new 4-phenyl-1,8-naphthyridine derivative affects carcinoma cell proliferation by impairing cell cycle progression and inducing apoptosis. Anticancer Agents Med Chem. 2012 Jul; 12(6):653-62. PMID: 22263796.
      View in: PubMed
    16. Mantuano E, Henry K, Yamauchi T, Hiramatsu N, Yamauchi K, Orita S, Takahashi K, Lin JH, Gonias SL, Campana WM. The unfolded protein response is a major mechanism by which LRP1 regulates Schwann cell survival after injury. J Neurosci. 2011 Sep 21; 31(38):13376-85. PMID: 21940431; PMCID: PMC3188465.
      View in: PubMed, PubMed Central
    17. Mantuano E, Jo M, Gonias SL, Campana WM. Low density lipoprotein receptor-related protein (LRP1) regulates Rac1 and RhoA reciprocally to control Schwann cell adhesion and migration. J Biol Chem. 2010 May 07; 285(19):14259-66. PMID: 20197276; PMCID: PMC2863187.
      View in: PubMed, PubMed Central
    18. Inoue G, Gaultier A, Li X, Mantuano E, Richardson G, Takahashi K, Campana WM. Erythropoietin promotes Schwann cell migration and assembly of the provisional extracellular matrix by recruiting beta1 integrin to the cell surface. Glia. 2010 Mar; 58(4):399-409. PMID: 19705458; PMCID: PMC2807473.
      View in: PubMed, PubMed Central
    19. Shi Y, Mantuano E, Inoue G, Campana WM, Gonias SL. Ligand binding to LRP1 transactivates Trk receptors by a Src family kinase-dependent pathway. Sci Signal. 2009 Apr 28; 2(68):ra18. PMID: 19401592; PMCID: PMC2696635.
      View in: PubMed, PubMed Central
    20. Mantuano E, Inoue G, Li X, Takahashi K, Gaultier A, Gonias SL, Campana WM. The hemopexin domain of matrix metalloproteinase-9 activates cell signaling and promotes migration of schwann cells by binding to low-density lipoprotein receptor-related protein. J Neurosci. 2008 Nov 05; 28(45):11571-82. PMID: 18987193; PMCID: PMC3837707.
      View in: PubMed, PubMed Central
    21. Gallo D, Battaglia A, Mantuano E, Travaglia D, De Stefano I, Buzzonetti A, Scambia G. 17beta-Estradiol and soy phytochemicals selectively induce a type 2 polarization in mesenteric lymph nodes of ovariectomized rats. Menopause. 2008 Jul-Aug; 15(4 Pt 1):718-25. PMID: 18520337.
      View in: PubMed
    22. Gallo D, Zannoni GF, De Stefano I, Mosca M, Ferlini C, Mantuano E, Scambia G. Soy phytochemicals decrease nonsmall cell lung cancer growth in female athymic mice. J Nutr. 2008 Jul; 138(7):1360-4. PMID: 18567761.
      View in: PubMed
    23. Mantuano E, Mukandala G, Li X, Campana WM, Gonias SL. Molecular dissection of the human alpha2-macroglobulin subunit reveals domains with antagonistic activities in cell signaling. J Biol Chem. 2008 Jul 18; 283(29):19904-11. PMID: 18499670; PMCID: PMC2459272.
      View in: PubMed, PubMed Central
    24. Gallo D, Mantuano E, Fabrizi M, Ferlini C, Mozzetti S, De Stefano I, Scambia G. Effects of a phytoestrogen-containing soy extract on the growth-inhibitory activity of ICI 182 780 in an experimental model of estrogen-dependent breast cancer. Endocr Relat Cancer. 2007 Jun; 14(2):317-24. PMID: 17639047.
      View in: PubMed
    25. Calderone V, Giorgi I, Livi O, Martinotti E, Mantuano E, Martelli A, Nardi A. Benzoyl and/or benzyl substituted 1,2,3-triazoles as potassium channel activators. VIII. Eur J Med Chem. 2005 Jun; 40(6):521-8. PMID: 15922836.
      View in: PubMed
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