Douglas Smith

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Title(s)	Professor, Physics
School	Vc-academic Affairs
Address	9500 Gilman Drive # La Jolla CA 92093
vCard	Download vCard

Research

research activities and funding

Linking Kinetics, Subunit Coordination & Structure of a Viral DNA Packaging Motor
NIH R01GM118817Jul 1, 2016 - Jun 30, 2021
Role: Co-Principal Investigator

Mechanisms of Viral DNA Packaging: Biophysical, Biochemical, & Genetic Analysis
NIH R01GM088186May 1, 2011 - Apr 30, 2016
Role: Principal Investigator

Bibliographic

selected publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

Altmetrics Details

PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Single-molecule measurements of bacteriophage lambda DNA packaging using purified terminase motor proteins and E. coli integration host factor. Sci Rep. 2025 Feb 27; 15(1):7093. Rawson B, Yang Q, Catalano CE, Smith DE. PMID: 40016253; PMCID: PMC11868608.

View in: PubMed Mentions: Fields:
Sci Science
Translation:Cells
Functional Dissection of a Viral DNA Packaging Machine's Walker B Motif. J Mol Biol. 2019 11 08; 431(22):4455-4474. delToro D, Ortiz D, Ordyan M, Pajak J, Sippy J, Catala A, Oh CS, Vu A, Arya G, Smith DE, Catalano CE, Feiss M. PMID: 31473160; PMCID: PMC7416571.

View in: PubMed Mentions: 10 Fields:
Mol Molecular Biology
Translation:Cells
Nucleotide-dependent DNA gripping and an end-clamp mechanism regulate the bacteriophage T4 viral packaging motor. Nat Commun. 2018 12 21; 9(1):5434. Ordyan M, Alam I, Mahalingam M, Rao VB, Smith DE. PMID: 30575768; PMCID: PMC6303390.

View in: PubMed Mentions: 19 Fields:
Bio Biology Sci Science
Translation:Cells
Walker-A Motif Acts to Coordinate ATP Hydrolysis with Motor Output in Viral DNA Packaging. J Mol Biol. 2016 07 03; 428(13):2709-29. delToro D, Ortiz D, Ordyan M, Sippy J, Oh CS, Keller N, Feiss M, Catalano CE, Smith DE. PMID: 27139643; PMCID: PMC4905814.

View in: PubMed Mentions: 24 Fields:
Mol Molecular Biology
Translation:Cells
Continuous allosteric regulation of a viral packaging motor by a sensor that detects the density and conformation of packaged DNA. Biophys J. 2015 Jan 20; 108(2):315-24. Berndsen ZT, Keller N, Smith DE. PMID: 25606680; PMCID: PMC4302192.

View in: PubMed Mentions: 19 Fields:
Bio Biophysics
Translation:Cells
Nonequilibrium dynamics and ultraslow relaxation of confined DNA during viral packaging. Proc Natl Acad Sci U S A. 2014 Jun 10; 111(23):8345-50. Berndsen ZT, Keller N, Grimes S, Jardine PJ, Smith DE. PMID: 24912187; PMCID: PMC4060647.

View in: PubMed Mentions: 36 Fields:
Sci Science
Translation:Cells