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Deborah Witherden

Title(s)Staff Res Assoc , Division of Biological Science
SchoolVc-academic Affairs
Address9500 Gilman Drive #0377
La Jolla CA 92093
Phone000-000-NULL
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Get in Touch With Dendritic Epithelial T Cells! Front Immunol. 2020; 11:1656. Thelen F, Witherden DA. PMID: 32849572.
      View in: PubMed   Mentions:    Fields:    
    2. B1 and B2 kinin receptor blockade improves psoriasis-like disease. Br J Pharmacol. 2020 Aug; 177(15):3535-3551. Soley BDS, Silva LM, Mendes DAGB, Báfica A, Pesquero JB, Bader M, Witherden DA, Havran WL, Calixto JB, Otuki MF, Cabrini DA. PMID: 32335893.
      View in: PubMed   Mentions: 1     Fields:    
    3. Heterogenous Populations of Tissue-Resident CD8+ T Cells Are Generated in Response to Infection and Malignancy. Immunity. 2020 May 19; 52(5):808-824.e7. Milner JJ, Toma C, He Z, Kurd NS, Nguyen QP, McDonald B, Quezada L, Widjaja CE, Witherden DA, Crowl JT, Shaw LA, Yeo GW, Chang JT, Omilusik KD, Goldrath AW. PMID: 32433949.
      View in: PubMed   Mentions:    Fields:    
    4. Wendy L. Havran, PhD: 1955-2020. Cells. 2020 Apr 22; 9(4). Witherden DA. PMID: 32331225.
      View in: PubMed   Mentions:    Fields:    
    5. The Role of Tissue-resident T Cells in Stress Surveillance and Tissue Maintenance. Cells. 2020 Mar 11; 9(3). Johnson MD, Witherden DA, Havran WL. PMID: 32168884.
      View in: PubMed   Mentions: 1     Fields:    
    6. Origins of CD4+ circulating and tissue-resident memory T-cells. Immunology. 2019 05; 157(1):3-12. Nguyen QP, Deng TZ, Witherden DA, Goldrath AW. PMID: 30897205.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    7. Coreceptors and Their Ligands in Epithelial ?d T Cell Biology. Front Immunol. 2018; 9:731. Witherden DA, Johnson MD, Havran WL. PMID: 29686687.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    8. Stimulation of hair follicle stem cell proliferation through an IL-1 dependent activation of ?dT-cells. Elife. 2017 12 04; 6. Lee P, Gund R, Dutta A, Pincha N, Rana I, Ghosh S, Witherden D, Kandyba E, MacLeod A, Kobielak K, Havran WL, Jamora C. PMID: 29199946.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    9. ?d T cells in homeostasis and host defence of epithelial barrier tissues. Nat Rev Immunol. 2017 Dec; 17(12):733-745. Nielsen MM, Witherden DA, Havran WL. PMID: 28920588.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    10. All hands on DE(T)C: Epithelial-resident ?d T cells respond to tissue injury. Cell Immunol. 2015 Jul; 296(1):57-61. Ramirez K, Witherden DA, Havran WL. PMID: 25958272.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    11. NKG2D-dependent activation of dendritic epidermal T cells in contact hypersensitivity. J Invest Dermatol. 2015 May; 135(5):1311-1319. Nielsen MM, Dyring-Andersen B, Schmidt JD, Witherden D, Lovato P, Woetmann A, Ødum N, Poulsen SS, Havran WL, Geisler C, Bonefeld CM. PMID: 25634359.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    12. Multiple Receptor-Ligand Interactions Direct Tissue-Resident ?d T Cell Activation. Front Immunol. 2014; 5:602. Witherden DA, Ramirez K, Havran WL. PMID: 25505467.
      View in: PubMed   Mentions: 4     Fields:    
    13. IL-1ß-dependent activation of dendritic epidermal T cells in contact hypersensitivity. J Immunol. 2014 Apr 01; 192(7):2975-83. Nielsen MM, Lovato P, MacLeod AS, Witherden DA, Skov L, Dyring-Andersen B, Dabelsteen S, Woetmann A, Ødum N, Havran WL, Geisler C, Bonefeld CM. PMID: 24600030.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    14. Dendritic epidermal T cells regulate skin antimicrobial barrier function. J Clin Invest. 2013 Oct; 123(10):4364-74. MacLeod AS, Hemmers S, Garijo O, Chabod M, Mowen K, Witherden DA, Havran WL. PMID: 24051381.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    15. Cross-talk between intraepithelial ?d T cells and epithelial cells. J Leukoc Biol. 2013 Jul; 94(1):69-76. Witherden DA, Havran WL. PMID: 23620015.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    16. EPCR: a stress trigger for ?d T cells. Nat Immunol. 2012 Sep; 13(9):812-4. Witherden DA, Havran WL. PMID: 22910386.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    17. The CD100 receptor interacts with its plexin B2 ligand to regulate epidermal ?d T cell function. Immunity. 2012 Aug 24; 37(2):314-25. Witherden DA, Watanabe M, Garijo O, Rieder SE, Sarkisyan G, Cronin SJ, Verdino P, Wilson IA, Kumanogoh A, Kikutani H, Teyton L, Fischer WH, Havran WL. PMID: 22902232.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    18. Cutting edge: dendritic epidermal ?d T cell ligands are rapidly and locally expressed by keratinocytes following cutaneous wounding. J Immunol. 2012 Apr 01; 188(7):2972-6. Komori HK, Witherden DA, Kelly R, Sendaydiego K, Jameson JM, Teyton L, Havran WL. PMID: 22393149.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    19. cDNA sequence and Fab crystal structure of HL4E10, a hamster IgG lambda light chain antibody stimulatory for ?d T cells. PLoS One. 2011; 6(5):e19828. Verdino P, Witherden DA, Podshivalova K, Rieder SE, Havran WL, Wilson IA. PMID: 21629689.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    20. Molecular aspects of epithelial ?d T cell regulation. Trends Immunol. 2011 Jun; 32(6):265-71. Witherden DA, Havran WL. PMID: 21481636.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    21. Molecular insights into ?d T cell costimulation by an anti-JAML antibody. Structure. 2011 Jan 12; 19(1):80-9. Verdino P, Witherden DA, Ferguson MS, Corper AL, Schiefner A, Havran WL, Wilson IA. PMID: 21220118.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    22. Costimulating epithelial ?d T cells. Cell Cycle. 2011 Jan 01; 10(1):4-5. Witherden DA, Havran WL. PMID: 21191174.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    23. The molecular interaction of CAR and JAML recruits the central cell signal transducer PI3K. Science. 2010 Sep 03; 329(5996):1210-4. Verdino P, Witherden DA, Havran WL, Wilson IA. PMID: 20813955.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    24. The junctional adhesion molecule JAML is a costimulatory receptor for epithelial gammadelta T cell activation. Science. 2010 Sep 03; 329(5996):1205-10. Witherden DA, Verdino P, Rieder SE, Garijo O, Mills RE, Teyton L, Fischer WH, Wilson IA, Havran WL. PMID: 20813954.
      View in: PubMed   Mentions: 76     Fields:    Translation:AnimalsCells
    25. Characterization and TCR variable region gene use of mouse resident nasal gammadelta T lymphocytes. J Leukoc Biol. 2008 Nov; 84(5):1259-63. Kim CH, Witherden DA, Havran WL. PMID: 18667688.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    26. Epithelial cells and their neighbors. III. Interactions between intraepithelial lymphocytes and neighboring epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2005 Oct; 289(4):G627-30. Havran WL, Jameson JM, Witherden DA. PMID: 16160077.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    27. Gammadelta T cell-induced hyaluronan production by epithelial cells regulates inflammation. J Exp Med. 2005 Apr 18; 201(8):1269-79. Jameson JM, Cauvi G, Sharp LL, Witherden DA, Havran WL. PMID: 15837812.
      View in: PubMed   Mentions: 57     Fields:    Translation:AnimalsCells
    28. Gamma delta T cell homeostasis is controlled by IL-7 and IL-15 together with subset-specific factors. J Immunol. 2005 Apr 15; 174(8):4606-12. Baccala R, Witherden D, Gonzalez-Quintial R, Dummer W, Surh CD, Havran WL, Theofilopoulos AN. PMID: 15814683.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    29. Dendritic epidermal T-cell activation. Crit Rev Immunol. 2005; 25(1):1-18. Sharp LL, Jameson JM, Witherden DA, Komori HK, Havran WL. PMID: 15833080.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    30. Regulation of skin cell homeostasis by gamma delta T cells. Front Biosci. 2004 Sep 01; 9:2640-51. Jameson JM, Sharp LL, Witherden DA, Havran WL. PMID: 15358587.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    31. A keratinocyte-responsive gamma delta TCR is necessary for dendritic epidermal T cell activation by damaged keratinocytes and maintenance in the epidermis. J Immunol. 2004 Mar 15; 172(6):3573-9. Jameson JM, Cauvi G, Witherden DA, Havran WL. PMID: 15004158.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    32. T-cell effector mechanisms: gammadelta and CD1d-restricted subsets. Curr Opin Immunol. 2003 Jun; 15(3):349-53. Jameson J, Witherden D, Havran WL. PMID: 12787763.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
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