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Deborah Kado

Title(s)Professor, Medicine
SchoolHealth Sciences
Phone858-534-4309
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    Dr. Kado is Professor at the University of California, San Diego School of Medicine. She is an internist and geriatrician with a primary research focus on osteoporosis and the related disorder hyperkyphosis. She is a successfully funded National Institute's of Health researcher and is internationally recognized in her field of expertise. Dr. Kado graduated from Cornell University Medical College, completed her residency in internal medicine, served as chief resident, and then did post-residency fellowships in clinical research at UCSF and in geriatrics at UCLA. She subsequently completed a Master of Sciences Degree in Epidemiology at the UCLA School of Public Health. Dr. Kado serves as the Deputy Director of Clinical Research and Education for the Stein Institute for Research on Aging and also is the Osteoporosis Clinic Director for the UCSD Health System. Dr. Kado has a joint appointment in the Division of Preventive Medicine, Department of Family Medicine and Public Health and the Division of Endocrinology, Department of Medicine, and is an associate member of the UC San Diego Moores Cancer Center.

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    Osteoporatic Fractures in Men (MrOS)
    NIH/NIA U01AG042168Aug 1, 2013 - Jul 31, 2018
    Role: Principal Investigator
    BIOLOGICAL AND STRUCTURAL PREDICTORS OF KYPHOSIS PROGRESSION IN OLDER MEN
    NIH/NIAMS R01AR060828Apr 1, 2011 - Mar 31, 2014
    Role: Principal Investigator
    Causes and Consequences of Hyperkyphosis in Older Persons
    NIH/NIA R56AG024246Sep 1, 2004 - Jun 30, 2011
    Role: Principal Investigator
    Causes and Consequences of Hyperkyphosis in Older Women
    NIH/NIA R01AG024246Sep 1, 2004 - Jun 30, 2008
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Shardell M, Parimi N, Langsetmo L, Tanaka T, Jiang L, Orwoll E, Shikany JM, Kado DM, Cawthon PM. Comparing Analytical Methods for the Gut Microbiome and Aging: Gut Microbial Communities and Body Weight in the Osteoporotic Fractures in Men (MrOS) Study. J Gerontol A Biol Sci Med Sci. 2020 Feb 06. PMID: 32025711.
      View in: PubMed
    2. Winger ME, Caserotti P, Cauley JA, Boudreau RM, Piva SR, Cawthon PM, Harris TB, Barrett-Connor E, Fink HA, Kado DM, Strotmeyer ES. Associations between novel jump test measures, grip strength, and physical performance: the Osteoporotic Fractures in Men (MrOS) Study. Aging Clin Exp Res. 2019 Dec 18. PMID: 31853832.
      View in: PubMed
    3. Buchbinder R, Ebeling PR, Akesson K, Bauer DC, Eastell R, Fink HA, Giangregorio L, Guanabens N, Kado D, Kallmes D, Katzman W, Rodriguez A, Wermers R, Wilson HA, Bouxsein ML. Response to: Some Questions About the Article "The Efficacy and Safety of Vertebral Augmentation: A Second ASBMR Task Force Report". J Bone Miner Res. 2020 Jan; 35(1):212-213. PMID: 31743502.
      View in: PubMed
    4. Woods GN, Ewing SK, Sigurdsson S, Kado DM, Eiriksdottir G, Gudnason V, Hue TF, Lang TF, Vittinghoff E, Harris TB, Rosen C, Xu K, Li X, Schwartz AV. Greater Bone Marrow Adiposity Predicts Bone Loss in Older Women. J Bone Miner Res. 2020 Feb; 35(2):326-332. PMID: 31618468.
      View in: PubMed
    5. Shikany JM, Demmer RT, Johnson AJ, Fino NF, Meyer K, Ensrud KE, Lane NE, Orwoll ES, Kado DM, Zmuda JM, Langsetmo L. Association of dietary patterns with the gut microbiota in older, community-dwelling men. Am J Clin Nutr. 2019 Oct 01; 110(4):1003-1014. PMID: 31504105.
      View in: PubMed
    6. Orwoll ES, Fino NF, Gill TM, Cauley JA, Strotmeyer ES, Ensrud KE, Kado DM, Barrett-Connor E, Bauer DC, Cawthon PM, Lapidus J. The Relationships Between Physical Performance, Activity Levels, and Falls in Older Men. J Gerontol A Biol Sci Med Sci. 2019 Aug 16; 74(9):1475-1483. PMID: 30383210.
      View in: PubMed
    7. Ebeling PR, Akesson K, Bauer DC, Buchbinder R, Eastell R, Fink HA, Giangregorio L, Guanabens N, Kado D, Kallmes D, Katzman W, Rodriguez A, Wermers R, Wilson HA, Bouxsein ML. Response Letter to the Editor-Diamond et al, JBMR. J Bone Miner Res. 2019 Jun; 34(6):1185-1186. PMID: 31135998.
      View in: PubMed
    8. Cawthon PM, Orwoll ES, Peters KE, Ensrud KE, Cauley JA, Kado DM, Stefanick ML, Shikany JM, Strotmeyer ES, Glynn NW, Caserotti P, Shankaran M, Hellerstein M, Cummings SR, Evans WJ. Strong Relation Between Muscle Mass Determined by D3-creatine Dilution, Physical Performance, and Incidence of Falls and Mobility Limitations in a Prospective Cohort of Older Men. J Gerontol A Biol Sci Med Sci. 2019 05 16; 74(6):844-852. PMID: 29897420.
      View in: PubMed
    9. Ebeling PR, Akesson K, Bauer DC, Buchbinder R, Eastell R, Fink HA, Giangregorio L, Guanabens N, Kado D, Kallmes D, Katzman W, Rodriguez A, Wermers R, Wilson HA, Bouxsein ML. The Efficacy and Safety of Vertebral Augmentation: A Second ASBMR Task Force Report. J Bone Miner Res. 2019 01; 34(1):3-21. PMID: 30677181.
      View in: PubMed
    10. Woods GN, Ewing SK, Sigurdsson S, Kado DM, Ix JH, Hue TF, Eiriksdottir G, Xu K, Gudnason V, Lang TF, Vittinghoff E, Harris TB, Rosen CJ, Li X, Schwartz AV. Chronic Kidney Disease Is Associated With Greater Bone Marrow Adiposity. J Bone Miner Res. 2018 12; 33(12):2158-2164. PMID: 30075054.
      View in: PubMed
    11. Woods GN, Huang MH, Cawthon PM, McDaniels-Davidson C, Fink HA, Kado DM. Patterns of menopausal hormone therapy use and hyperkyphosis in older women. Menopause. 2018 07; 25(7):738-743. PMID: 29462096.
      View in: PubMed
    12. Schousboe JT, Kats AM, Langsetmo L, Taylor BC, Vo TN, Kado DM, Fink HA, Ensrud KE. Associations of recent weight loss with health care costs and utilization among older women. PLoS One. 2018; 13(1):e0191642. PMID: 29377919.
      View in: PubMed
    13. Stone KL, Lui LY, Christen WG, Troen AM, Bauer DC, Kado D, Schambach C, Cummings SR, Manson JE. Effect of Combination Folic Acid, Vitamin B6 , and Vitamin B12 Supplementation on Fracture Risk in Women: A Randomized, Controlled Trial. J Bone Miner Res. 2017 Dec; 32(12):2331-2338. PMID: 29244251.
      View in: PubMed
    14. Gourlay ML, Ritter VS, Fine JP, Overman RA, Schousboe JT, Cawthon PM, Orwoll ES, Nguyen TV, Lane NE, Cummings SR, Kado DM, Lapidus JA, Diem SJ, Ensrud KE. Correction to: Comparison of fracture risk assessment tools in older men without prior hip or spine fracture: the MrOS study. Arch Osteoporos. 2017 11 07; 12(1):99. PMID: 29116457.
      View in: PubMed
    15. Gourlay ML, Ritter VS, Fine JP, Overman RA, Schousboe JT, Cawthon PM, Orwoll ES, Nguyen TV, Lane NE, Cummings SR, Kado DM, Lapidus JA, Diem SJ, Ensrud KE. Comparison of fracture risk assessment tools in older men without prior hip or spine fracture: the MrOS study. Arch Osteoporos. 2017 Oct 20; 12(1):91. PMID: 29052793.
      View in: PubMed
    16. Fink HA, Litwack-Harrison S, Ensrud KE, Shen J, Schousboe JT, Cawthon PM, Cauley JA, Lane NE, Taylor BC, Barrett-Connor E, Kado DM, Cummings SR, Marshall LM. Association of Incident, Clinically Undiagnosed Radiographic Vertebral Fractures With Follow-Up Back Pain Symptoms in Older Men: the Osteoporotic Fractures in Men (MrOS) Study. J Bone Miner Res. 2017 Nov; 32(11):2263-2268. PMID: 28880398.
      View in: PubMed
    17. Marshall LM, Litwack-Harrison S, Makris UE, Kado DM, Cawthon PM, Deyo RA, Carlson NL, Nevitt MC. A Prospective Study of Back Pain and Risk of Falls Among Older Community-dwelling Men. J Gerontol A Biol Sci Med Sci. 2017 Sep 01; 72(9):1264-1269. PMID: 27852636.
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    18. Katzman WB, Parimi N, Mansoori Z, Nardo L, Kado DM, Cawthon PM, Marshall LM, Schousboe JT, Lane NE. Cross-Sectional and Longitudinal Associations of Diffuse Idiopathic Skeletal Hyperostosis and Thoracic Kyphosis in Older Men and Women. Arthritis Care Res (Hoboken). 2017 08; 69(8):1245-1252. PMID: 27723250.
      View in: PubMed
    19. Cawthon PM, Patel S, Ewing SK, Lui LY, Cauley JA, Lyons JG, Fredman L, Kado DM, Hoffman AR, Lane NE, Ensrud KE, Cummings SR, Orwoll ES. Bone Loss at the Hip and Subsequent Mortality in Older Men: The Osteoporotic Fractures in Men (MrOS) Study. JBMR Plus. 2017 Aug; 1(1):31-35. PMID: 29124252.
      View in: PubMed
    20. Katzman WB, Huang MH, Kritz-Silverstein D, Barrett-Connor E, Kado DM. Diffuse Idiopathic Skeletal Hyperostosis (DISH) and Impaired Physical Function: The Rancho Bernardo Study. J Am Geriatr Soc. 2017 Jul; 65(7):1476-1481. PMID: 28369706.
      View in: PubMed
    21. Ensrud KE, Harrison SL, Cauley JA, Langsetmo L, Schousboe JT, Kado DM, Gourlay ML, Lyons JG, Fredman L, Napoli N, Crandall CJ, Lewis CE, Orwoll ES, Stefanick ML, Cawthon PM. Impact of Competing Risk of Mortality on Association of Weight Loss With Risk of Central Body Fractures in Older Men: A Prospective Cohort Study. J Bone Miner Res. 2017 Mar; 32(3):624-632. PMID: 27739103.
      View in: PubMed
    22. Woods GN, Huang MH, Cawthon PM, Laughlin GA, Schousboe JT, McDaniels-Davidson C, Cauley JA, Orwoll E, Barrett-Connor E, Kado DM. SHBG, Sex Steroids, and Kyphosis in Older Men: The MrOS Study. J Bone Miner Res. 2016 12; 31(12):2123-2128. PMID: 27355438.
      View in: PubMed
    23. Cauley JA, Cawthon PM, Peters KE, Cummings SR, Ensrud KE, Bauer DC, Taylor BC, Shikany JM, Hoffman AR, Lane NE, Kado DM, Stefanick ML, Orwoll ES. Risk Factors for Hip Fracture in Older Men: The Osteoporotic Fractures in Men Study (MrOS). J Bone Miner Res. 2016 10; 31(10):1810-1819. PMID: 26988112.
      View in: PubMed
    24. McDaniels-Davidson CR, Kritz-Silverstein D, Huang MH, Laughlin GA, Johnson S, Haapalahti J, Schneider DL, Barrett-Connor E, Kado DM. The association between bone turnover markers and kyphosis in community-dwelling older adults. Bone Rep. 2016 Dec; 5:57-61. PMID: 27868084.
      View in: PubMed
    25. Ensrud KE, Blackwell TL, Fink HA, Zhang J, Cauley JA, Cawthon PM, Black DM, Bauer DC, Curtis JR, Orwoll ES, Barrett-Connor E, Kado DM, Marshall LM, Shikany JM, Schousboe JT. What Proportion of Incident Radiographic Vertebral Fractures in Older Men Is Clinically Diagnosed and Vice Versa: A Prospective Study. J Bone Miner Res. 2016 08; 31(8):1500-3. PMID: 26969847.
      View in: PubMed
    26. Gourlay ML, Overman RA, Fine JP, Filteau G, Cawthon PM, Schousboe JT, Orwoll ES, Wilt TJ, Nguyen TV, Lane NE, Szulc P, Taylor BC, Dam TT, Nielson CM, Cauley JA, Barrett-Connor E, Fink HA, Lapidus JA, Kado DM, Diem SJ, Ensrud KE. Time to Osteoporosis and Major Fracture in Older Men: The MrOS Study. Am J Prev Med. 2016 06; 50(6):727-736. PMID: 26821835.
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    27. Marshall LM, Litwack-Harrison S, Cawthon PM, Kado DM, Deyo RA, Makris UE, Carlson HL, Nevitt MC. A Prospective Study of Back Pain and Risk of Falls Among Older Community-dwelling Women. J Gerontol A Biol Sci Med Sci. 2016 09; 71(9):1177-83. PMID: 26757988.
      View in: PubMed
    28. Cawthon PM, Schousboe JT, Harrison SL, Ensrud KE, Black D, Cauley JA, Cummings SR, LeBlanc ES, Laughlin GA, Nielson CM, Broughton A, Kado DM, Hoffman AR, Jamal SA, Barrett-Connor E, Orwoll ES. Sex hormones, sex hormone binding globulin, and vertebral fractures in older men. Bone. 2016 Mar; 84:271-278. PMID: 26778261.
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    29. Cawthon PM, Blackwell TL, Cauley J, Kado DM, Barrett-Connor E, Lee CG, Hoffman AR, Nevitt M, Stefanick ML, Lane NE, Ensrud KE, Cummings SR, Orwoll ES. Evaluation of the Usefulness of Consensus Definitions of Sarcopenia in Older Men: Results from the Observational Osteoporotic Fractures in Men Cohort Study. J Am Geriatr Soc. 2015 Nov; 63(11):2247-59. PMID: 26502831.
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    30. Chalhoub D, Cawthon PM, Ensrud KE, Stefanick ML, Kado DM, Boudreau R, Greenspan S, Newman AB, Zmuda J, Orwoll ES, Cauley JA. Risk of Nonspine Fractures in Older Adults with Sarcopenia, Low Bone Mass, or Both. J Am Geriatr Soc. 2015 Sep; 63(9):1733-40. PMID: 26310882.
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    31. Katzman WB, Vittinghoff E, Kado DM, Schafer AL, Wong SS, Gladin A, Lane NE. Study of Hyperkyphosis, Exercise and Function (SHEAF) Protocol of a Randomized Controlled Trial of Multimodal Spine-Strengthening Exercise in Older Adults With Hyperkyphosis. Phys Ther. 2016 Mar; 96(3):371-81. PMID: 26251480.
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    32. Ensrud KE, Blackwell TL, Cawthon PM, Bauer DC, Fink HA, Schousboe JT, Black DM, Orwoll ES, Kado DM, Cauley JA, Mackey DC. Degree of Trauma Differs for Major Osteoporotic Fracture Events in Older Men Versus Older Women. J Bone Miner Res. 2016 Jan; 31(1):204-7. PMID: 26178795.
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    33. Katzman WB, Harrison SL, Fink HA, Marshall LM, Orwoll E, Barrett-Connor E, Cawthon PM, Kado DM. Physical function in older men with hyperkyphosis. J Gerontol A Biol Sci Med Sci. 2015 May; 70(5):635-40. PMID: 25431353.
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    34. Kado DM, Miller-Martinez D, Lui LY, Cawthon P, Katzman WB, Hillier TA, Fink HA, Ensrud KE. Hyperkyphosis, kyphosis progression, and risk of non-spine fractures in older community dwelling women: the study of osteoporotic fractures (SOF). J Bone Miner Res. 2014 Oct; 29(10):2210-6. PMID: 24715607.
      View in: PubMed
    35. Cawthon PM, Blackwell TL, Marshall LM, Fink HA, Kado DM, Ensrud KE, Cauley JA, Black D, Orwoll ES, Cummings SR, Schousboe JT. Physical performance and radiographic and clinical vertebral fractures in older men. J Bone Miner Res. 2014 Sep; 29(9):2101-8. PMID: 25042072.
      View in: PubMed
    36. Schousboe JT, Rosen HR, Vokes TJ, Cauley JA, Cummings SR, Nevitt M, Black DM, Orwoll ES, Kado DM, Ensrud KE. Prediction models of prevalent radiographic vertebral fractures among older women. J Clin Densitom. 2014 Jul-Sep; 17(3):378-85. PMID: 24582085.
      View in: PubMed
    37. Katzman WB, Miller-Martinez D, Marshall LM, Lane NE, Kado DM. Kyphosis and paraspinal muscle composition in older men: a cross-sectional study for the Osteoporotic Fractures in Men (MrOS) research group. BMC Musculoskelet Disord. 2014 Jan 16; 15:19. PMID: 24428860.
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    38. Schousboe JT, Rosen HR, Vokes TJ, Cauley JA, Cummings SR, Nevitt MC, Black DM, Orwoll ES, Kado DM, Ensrud KE. Prediction models of prevalent radiographic vertebral fractures among older men. J Clin Densitom. 2014 Oct-Dec; 17(4):449-57. PMID: 24289883.
      View in: PubMed
    39. Lane NE, Parimi N, Corr M, Yao W, Cauley JA, Nielson CM, Ix JH, Kado D, Orwoll E. Association of serum fibroblast growth factor 23 (FGF23) and incident fractures in older men: the Osteoporotic Fractures in Men (MrOS) study. J Bone Miner Res. 2013 Nov; 28(11):2325-32. PMID: 23677793.
      View in: PubMed
    40. Katzman WB, Huang MH, Lane NE, Ensrud KE, Kado DM. Kyphosis and decline in physical function over 15 years in older community-dwelling women: the Study of Osteoporotic Fractures. J Gerontol A Biol Sci Med Sci. 2013 Aug; 68(8):976-83. PMID: 23633167.
      View in: PubMed
    41. Kado DM, Huang MH, Karlamangla AS, Cawthon P, Katzman W, Hillier TA, Ensrud K, Cummings SR. Factors associated with kyphosis progression in older women: 15 years' experience in the study of osteoporotic fractures. J Bone Miner Res. 2013 Jan; 28(1):179-87. PMID: 22865329.
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    42. Sugi MT, Sheridan K, Lewis L, Huang MH, Nattiv A, Kado DM, Bengs B. Active Referral Intervention following Fragility Fractures Leads to Enhanced Osteoporosis Follow-Up Care. J Osteoporos. 2012; 2012:234381. PMID: 22523716.
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    43. Hillier TA, Lui LY, Kado DM, LeBlanc ES, Vesco KK, Bauer DC, Cauley JA, Ensrud KE, Black DM, Hochberg MC, Cummings SR. Height loss in older women: risk of hip fracture and mortality independent of vertebral fractures. J Bone Miner Res. 2012 Jan; 27(1):153-9. PMID: 22072593.
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    44. Katzman W, Cawthon P, Hicks GE, Vittinghoff E, Shepherd J, Cauley JA, Harris T, Simonsick EM, Strotmeyer E, Womack C, Kado DM. Association of spinal muscle composition and prevalence of hyperkyphosis in healthy community-dwelling older men and women. J Gerontol A Biol Sci Med Sci. 2012 Feb; 67(2):191-5. PMID: 21878482.
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    45. Katzman WB, Vittinghoff E, Ensrud K, Black DM, Kado DM. Increasing kyphosis predicts worsening mobility in older community-dwelling women: a prospective cohort study. J Am Geriatr Soc. 2011 Jan; 59(1):96-100. PMID: 21198460.
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    46. Kado DM, Lui LY, Ensrud KE, Fink HA, Karlamangla AS, Cummings SR. Hyperkyphosis predicts mortality independent of vertebral osteoporosis in older women. Ann Intern Med. 2009 May 19; 150(10):681-7. PMID: 19451575.
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    47. Karlamangla AS, Sarkisian CA, Kado DM, Dedes H, Liao DH, Kim S, Reuben DB, Greendale GA, Moore AA. Light to moderate alcohol consumption and disability: variable benefits by health status. Am J Epidemiol. 2009 Jan 01; 169(1):96-104. PMID: 19022829.
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    48. Kado DM, Huang MH, Nguyen CB, Barrett-Connor E, Greendale GA. Hyperkyphotic posture and risk of injurious falls in older persons: the Rancho Bernardo Study. J Gerontol A Biol Sci Med Sci. 2007 Jun; 62(6):652-7. PMID: 17595423.
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    49. Chodosh J, Kado DM, Seeman TE, Karlamangla AS. Depressive symptoms as a predictor of cognitive decline: MacArthur Studies of Successful Aging. Am J Geriatr Psychiatry. 2007 May; 15(5):406-15. PMID: 17353297.
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    50. Kado DM, Christianson L, Palermo L, Smith-Bindman R, Cummings SR, Greendale GA. Comparing a supine radiologic versus standing clinical measurement of kyphosis in older women: the Fracture Intervention Trial. Spine (Phila Pa 1976). 2006 Feb 15; 31(4):463-7. PMID: 16481959.
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    51. Huang MH, Barrett-Connor E, Greendale GA, Kado DM. Hyperkyphotic posture and risk of future osteoporotic fractures: the Rancho Bernardo study. J Bone Miner Res. 2006 Mar; 21(3):419-23. PMID: 16491290.
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    52. Kado DM, Huang MH, Barrett-Connor E, Greendale GA. Hyperkyphotic posture and poor physical functional ability in older community-dwelling men and women: the Rancho Bernardo study. J Gerontol A Biol Sci Med Sci. 2005 May; 60(5):633-7. PMID: 15972617.
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    53. Kado DM, Karlamangla AS, Huang MH, Troen A, Rowe JW, Selhub J, Seeman TE. Homocysteine versus the vitamins folate, B6, and B12 as predictors of cognitive function and decline in older high-functioning adults: MacArthur Studies of Successful Aging. Am J Med. 2005 Feb; 118(2):161-7. PMID: 15694902.
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    54. Kado DM, Huang MH, Karlamangla AS, Barrett-Connor E, Greendale GA. Hyperkyphotic posture predicts mortality in older community-dwelling men and women: a prospective study. J Am Geriatr Soc. 2004 Oct; 52(10):1662-7. PMID: 15450042.
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    55. Kado DM, Lui LY, Cummings SR. Rapid resting heart rate: a simple and powerful predictor of osteoporotic fractures and mortality in older women. J Am Geriatr Soc. 2002 Mar; 50(3):455-60. PMID: 11943040.
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