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David Malinak

TitleResident Physician
InstitutionUniversity of California San Diego
DepartmentMedicine
Address200 W. Arbor Drive #8425
San Diego CA 92103
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Mezeiova E, Spilovska K, Nepovimova E, Gorecki L, Soukup O, Dolezal R, Malinak D, Janockova J, Jun D, Kuca K, Korabecny J. Profiling donepezil template into multipotent hybrids with antioxidant properties. J Enzyme Inhib Med Chem. 2018 Dec; 33(1):583-606. PMID: 29529892.
      View in: PubMed
    2. Honegr J, Malinak D, Dolezal R, Soukup O, Benkova M, Hroch L, Benek O, Janockova J, Kuca K, Prymula R. Rational design of novel TLR4 ligands by in silico screening and their functional and structural characterization in vitro. Eur J Med Chem. 2018 Feb 25; 146:38-46. PMID: 29407964.
      View in: PubMed
    3. Honegr J, Dolezal R, Malinak D, Benkova M, Soukup O, Almeida JSFD, Franca TCC, Kuca K, Prymula R. Rational Design of a New Class of Toll-Like Receptor 4 (TLR4) Tryptamine Related Agonists by Means of the Structure- and Ligand-Based Virtual Screening for Vaccine Adjuvant Discovery. Molecules. 2018 Jan 04; 23(1). PMID: 29300367.
      View in: PubMed
    4. Soukup O, Korabecny J, Malinak D, Nepovimova E, Pham NL, Musilek K, Hrabinova M, Hepnarova V, Dolezal R, Pavek P, Jost P, Kobrlova T, Jankockova J, Gorecki L, Psotka M, Nguyen TD, Box K, Outhwaite B, Ceckova M, Sorf A, Jun D, Kuca K. In vitro and in silico Evaluation of Non-Quaternary Reactivators of AChE as Antidotes of Organophosphorus Poisoning - a New Hope or a Blind Alley? Med Chem. 2018; 14(3):281-292. PMID: 29332594.
      View in: PubMed
    5. Smith S, Malinak D, Chang J, Schultz A, Brownell K. Addressing Food Insecurity in Family Medicine and Medical Education. Fam Med. 2017 Nov; 49(10):765-771. PMID: 29190401.
      View in: PubMed
    6. Gorecki L, Korabecny J, Musilek K, Nepovimova E, Malinak D, Kucera T, Dolezal R, Jun D, Soukup O, Kuca K. Progress in acetylcholinesterase reactivators and in the treatment of organophosphorus intoxication: a patent review (2006-2016). Expert Opin Ther Pat. 2017 Sep; 27(9):971-985. PMID: 28569609.
      View in: PubMed
    7. Smith S, Malinak D, Chang J, Perez M, Perez S, Settlecowski E, Rodriggs T, Hsu M, Abrew A, Aedo S. Implementation of a food insecurity screening and referral program in student-run free clinics in San Diego, California. Prev Med Rep. 2017 Mar; 5:134-139. PMID: 27990340.
      View in: PubMed
    8. Gorecki L, Korabecny J, Musilek K, Malinak D, Nepovimova E, Dolezal R, Jun D, Soukup O, Kuca K. SAR study to find optimal cholinesterase reactivator against organophosphorous nerve agents and pesticides. Arch Toxicol. 2016 Dec; 90(12):2831-2859. PMID: 27582056.
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    9. Dolezal R, Soukup O, Malinak D, Savedra RML, Marek J, Dolezalova M, Pasdiorova M, Salajkova S, Korabecny J, Honegr J, Ramalho TC, Kuca K. Towards understanding the mechanism of action of antibacterial N-alkyl-3-hydroxypyridinium salts: Biological activities, molecular modeling and QSAR studies. Eur J Med Chem. 2016 Oct 04; 121:699-711. PMID: 27341309.
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    10. Soukup O, Dolezal R, Malinak D, Marek J, Salajkova S, Pasdiorova M, Honegr J, Korabecny J, Nachtigal P, Nachon F, Jun D, Kuca K. Synthesis, antimicrobial evaluation and molecular modeling of 5-hydroxyisoquinolinium salt series; the effect of the hydroxyl moiety. Bioorg Med Chem. 2016 Feb 15; 24(4):841-8. PMID: 26774252.
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    11. Korabecny J, Andrs M, Nepovimova E, Dolezal R, Babkova K, Horova A, Malinak D, Mezeiova E, Gorecki L, Sepsova V, Hrabinova M, Soukup O, Jun D, Kuca K. 7-Methoxytacrine-p-Anisidine Hybrids as Novel Dual Binding Site Acetylcholinesterase Inhibitors for Alzheimer's Disease Treatment. Molecules. 2015 Dec 10; 20(12):22084-101. PMID: 26690394.
      View in: PubMed
    12. Nepovimova E, Korabecny J, Dolezal R, Babkova K, Ondrejicek A, Jun D, Sepsova V, Horova A, Hrabinova M, Soukup O, Bukum N, Jost P, Muckova L, Kassa J, Malinak D, Andrs M, Kuca K. Tacrine-Trolox Hybrids: A Novel Class of Centrally Active, Nonhepatotoxic Multi-Target-Directed Ligands Exerting Anticholinesterase and Antioxidant Activities with Low In Vivo Toxicity. J Med Chem. 2015 Nov 25; 58(22):8985-9003. PMID: 26503905.
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    13. Marek J, Malinak D, Dolezal R, Soukup O, Pasdiorova M, Dolezal M, Kuca K. Synthesis and disinfection effect of the pyridine-4-aldoxime based salts. Molecules. 2015 Feb 24; 20(3):3681-96. PMID: 25719739.
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    14. Honegr J, Soukup O, Doležal R, Malinak D, Penhaker M, Prymula R, Kuca K. Structural Properties of Potential Synthetic Vaccine Adjuvants - TLR Agonists. Curr Med Chem. 2015; 22(29):3306-25. PMID: 26295466.
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    15. Dolezal R, Korabecny J, Malinak D, Honegr J, Musilek K, Kuca K. Ligand-based 3D QSAR analysis of reactivation potency of mono- and bis-pyridinium aldoximes toward VX-inhibited rat acetylcholinesterase. J Mol Graph Model. 2015 Mar; 56:113-29. PMID: 25588616.
      View in: PubMed
    16. Malinak D, Dolezal R, Marek J, Salajkova S, Soukup O, Vejsova M, Korabecny J, Honegr J, Penhaker M, Musilek K, Kuca K. 6-Hydroxyquinolinium salts differing in the length of alkyl side-chain: synthesis and antimicrobial activity. Bioorg Med Chem Lett. 2014 Nov 15; 24(22):5238-41. PMID: 25442318.
      View in: PubMed