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David Kearns

Title(s)Emeritus Professor, Chemistry and Biochemistry
SchoolVc-academic Affairs
Address9500 Gilman Drive #0343
La Jolla CA 92093
Phone8/5-34--4466
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. 1H NMR studies of a 17-mer DNA duplex. Biochim Biophys Acta. 2002 Feb 20; 1574(1):93-9. Liu W, Vu HM, Kearns DR. PMID: 11955617.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    2. Solution structure of a mutant of transcription factor 1: implications for enhanced DNA binding. J Mol Biol. 2000 Sep 29; 302(4):821-30. Liu W, Vu HM, Geiduschek EP, Kearns DR. PMID: 10993726.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    3. Mechanisms for the enhanced thermal stability of a mutant of transcription factor 1 as explained by (1)H, (15)N and (13)C NMR chemical shifts and secondary structure analysis. Biochim Biophys Acta. 2000 Mar 16; 1478(1):113-24. Vu HM, Liu W, Grove A, Geiduschek EP, Kearns DR. PMID: 10719180.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    4. NMR-derived solution structure of a 17mer hydroxymethyluracil-containing DNA. Nucleic Acids Res. 1999 Nov 01; 27(21):4143-50. Vu HM, Pepe A, Mayol L, Kearns DR. PMID: 10518604.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    5. Specificity of hydroxylmethyluracil-containing DNA for transcription factor 1: structural insights. Biopolymers. 1999; 52(1):57-63. Vu HM, Pasternack LB, Kearns DR. PMID: 10737862.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    6. Nuclear magnetic resonance-based model of a TF1/HmU-DNA complex. Arch Biochem Biophys. 1997 Dec 15; 348(2):255-61. Silva MV, Pasternack LB, Kearns DR. PMID: 9434736.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    7. Secondary structure of T4 gene 33 protein. Fourier transform infrared and circular dichroic spectroscopic studies. Int J Biol Macromol. 1997 Apr; 20(2):115-21. Shao W, Kearns DR, Sanders GM. PMID: 9184943.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    8. Structure of the Bacillus subtilis phage SPO1-encoded type II DNA-binding protein TF1 in solution. J Mol Biol. 1996 Oct 25; 263(2):259-68. Jia X, Grove A, Ivancic M, Hsu VL, Geiduscheck EP, Kearns DR. PMID: 8913305.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    9. 1H NMR studies of the 5-(hydroxymethyl)-2'-deoxyuridine containing TF1 binding site. Nucleic Acids Res. 1996 Jul 15; 24(14):2740-5. Pasternack LB, Bramham J, Mayol L, Galeone A, Jia X, Kearns DR. PMID: 8759005.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    10. Structural characterization of d(CAACCCGTTG) and d(CAACGGGTTG) mini-hairpin loops by heteronuclear NMR: the effects of purines versus pyrimidines in DNA hairpins. Nucleic Acids Res. 1995 Apr 11; 23(7):1260-8. Avizonis DZ, Kearns DR. PMID: 7739905.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    11. Kinetic and thermodynamic characterization of DNA duplex-hairpin interconversion for two DNA decamers: d(CAACGGGTTG) and d(CAACCCGTTG). Biopolymers. 1995 Feb; 35(2):187-200. Avizonis DZ, Kearns DR. PMID: 7696564.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    12. Proton and nitrogen NMR sequence-specific assignments and secondary structure determination of the Bacillus subtilis SPO1-encoded transcription factor 1. Biochemistry. 1994 Jul 26; 33(29):8842-52. Jia X, Reisman JM, Hsu VL, Geiduschek EP, Parello J, Kearns DR. PMID: 8038176.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    13. Formation of multiple complexes between actinomycin D and a DNA hairpin: structural characterization by multinuclear NMR. Biochemistry. 1994 Jan 25; 33(3):651-64. Brown DR, Kurz M, Kearns DR, Hsu VL. PMID: 8292593.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    14. Deuterium relaxation and internal motion in solid Li-DNA. Biochemistry. 1990 Feb 20; 29(7):1717-21. Brandes R, Vold RR, Kearns DR, Rupprecht A. PMID: 2331461.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    15. Reduced DNA flexibility in complexes with a type II DNA binding protein. Biochemistry. 1990 Jan 30; 29(4):959-65. Härd T, Kearns DR. PMID: 2340287.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    16. A fluorescence study of the binding of Hoechst 33258 and DAPI to halogenated DNAs. Photochem Photobiol. 1990 Jan; 51(1):77-86. Härd T, Fan P, Kearns DR. PMID: 1689498.
      View in: PubMed   Mentions: 9     Fields:    
    17. Interaction of water with oriented DNA in the A- and B-form conformations. Biophys J. 1989 Oct; 56(4):683-91. Brandes R, Rupprecht A, Kearns DR. PMID: 2554988.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    18. A type II DNA-binding protein genetically engineered for fluorescence spectroscopy: the "arm" of transcription factor 1 binds in the DNA grooves. Biochemistry. 1989 Apr 04; 28(7):2813-9. Härd T, Sayre MH, Geiduschek EP, Kearns DR. PMID: 2742813.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    19. Fluorescence studies of a single tyrosine in a type II DNA binding protein. Biochemistry. 1989 Jan 10; 28(1):396-406. Härd T, Hsu V, Sayre MH, Geiduschek EP, Appelt K, Kearns DR. PMID: 2706265.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    20. Static disorder and librational motions of the purine bases in films of oriented Li-DNA. J Mol Biol. 1988 Jul 20; 202(2):321-32. Brandes R, Vold RR, Kearns DR, Rupprecht A. PMID: 3172220.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    21. Molecular mechanics and dynamics calculations on (dA)10.(dT)10 incorporating distance constraints derived from NMR relaxation measurements. Biochemistry. 1987 Jul 28; 26(15):4674-81. Behling RW, Rao SN, Kollman P, Kearns DR. PMID: 3663617.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    22. 1H NMR study of the binding of Bis(acridines) to d(AT)5.d(AT)5. 1. Mode of binding. Biochemistry. 1985 Mar 12; 24(6):1441-9. Assa-Munt N, Denny WA, Leupin W, Kearns DR. PMID: 12096751.
      View in: PubMed   Mentions: 8     Fields:    
    23. 1H NMR study of the binding of bis(acridines) to d(AT)5.d(AT)5. 2. Dynamic aspects. Biochemistry. 1985 Mar 12; 24(6):1449-60. Assa-Munt N, Leupin W, Denny WA, Kearns DR. PMID: 12096754.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    24. Unusual proton exchange properties of Z-form poly[d(G-C)]. Proc Natl Acad Sci U S A. 1985 Mar; 82(6):1594-8. Mirau PA, Kearns DR. PMID: 16578783.
      View in: PubMed   Mentions: 3     Fields:    
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