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    David Kearns

    TitleEmeritus Professor
    SchoolUniversity of California, San Diego
    DepartmentChemistry and Biochemistry
    Address9500 Gilman Drive #0343
    CA La Jolla 92093
    Phone858-534-4466
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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Liu W, Vu HM, Kearns D. 1H NMR studies of a 17-mer DNA duplex. Biochim Biophys Acta. 2002 Feb 20; 1574(1):93-9. PMID: 11955617.
        View in: PubMed
      2. Liu W, Vu HM, Geiduschek EP, Kearns D. Solution structure of a mutant of transcription factor 1: implications for enhanced DNA binding. J Mol Biol. 2000 Sep 29; 302(4):821-30. PMID: 10993726.
        View in: PubMed
      3. Vu HM, Liu W, Grove A, Geiduschek EP, Kearns D. Mechanisms for the enhanced thermal stability of a mutant of transcription factor 1 as explained by (1)H, (15)N and (13)C NMR chemical shifts and secondary structure analysis. Biochim Biophys Acta. 2000 Mar 16; 1478(1):113-24. PMID: 10719180.
        View in: PubMed
      4. Vu HM, Pepe A, Mayol L, Kearns D. NMR-derived solution structure of a 17mer hydroxymethyluracil-containing DNA. Nucleic Acids Res. 1999 Nov 1; 27(21):4143-50. PMID: 10518604.
        View in: PubMed
      5. Vu HM, Pasternack LB, Kearns D. Specificity of hydroxylmethyluracil-containing DNA for transcription factor 1: structural insights. Biopolymers. 1999; 52(1):57-63. PMID: 10737862.
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      6. Silva MV, Pasternack LB, Kearns D. Nuclear magnetic resonance-based model of a TF1/HmU-DNA complex. Arch Biochem Biophys. 1997 Dec 15; 348(2):255-61. PMID: 9434736.
        View in: PubMed
      7. Shao W, Kearns D, Sanders GM. Secondary structure of T4 gene 33 protein. Fourier transform infrared and circular dichroic spectroscopic studies. Int J Biol Macromol. 1997 Apr; 20(2):115-21. PMID: 9184943.
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      8. Jia X, Grove A, Ivancic M, Hsu VL, Geiduscheck EP, Kearns D. Structure of the Bacillus subtilis phage SPO1-encoded type II DNA-binding protein TF1 in solution. J Mol Biol. 1996 Oct 25; 263(2):259-68. PMID: 8913305.
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      9. Pasternack LB, Bramham J, Mayol L, Galeone A, Jia X, Kearns D. 1H NMR studies of the 5-(hydroxymethyl)-2'-deoxyuridine containing TF1 binding site. Nucleic Acids Res. 1996 Jul 15; 24(14):2740-5. PMID: 8759005.
        View in: PubMed
      10. Avizonis DZ, Kearns D. Structural characterization of d(CAACCCGTTG) and d(CAACGGGTTG) mini-hairpin loops by heteronuclear NMR: the effects of purines versus pyrimidines in DNA hairpins. Nucleic Acids Res. 1995 Apr 11; 23(7):1260-8. PMID: 7739905.
        View in: PubMed
      11. Avizonis DZ, Kearns D. Kinetic and thermodynamic characterization of DNA duplex-hairpin interconversion for two DNA decamers: d(CAACGGGTTG) and d(CAACCCGTTG). Biopolymers. 1995 Feb; 35(2):187-200. PMID: 7696564.
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      12. Jia X, Reisman JM, Hsu VL, Geiduschek EP, Parello J, Kearns D. Proton and nitrogen NMR sequence-specific assignments and secondary structure determination of the Bacillus subtilis SPO1-encoded transcription factor 1. Biochemistry. 1994 Jul 26; 33(29):8842-52. PMID: 8038176.
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      13. Brown DR, Kurz M, Kearns D, Hsu VL. Formation of multiple complexes between actinomycin D and a DNA hairpin: structural characterization by multinuclear NMR. Biochemistry. 1994 Jan 25; 33(3):651-64. PMID: 8292593.
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      14. Brandes R, Vold RR, Kearns D, Rupprecht A. Deuterium relaxation and internal motion in solid Li-DNA. Biochemistry. 1990 Feb 20; 29(7):1717-21. PMID: 2331461.
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      15. Härd T, Kearns D. Reduced DNA flexibility in complexes with a type II DNA binding protein. Biochemistry. 1990 Jan 30; 29(4):959-65. PMID: 2340287.
        View in: PubMed
      16. Härd T, Fan P, Kearns D. A fluorescence study of the binding of Hoechst 33258 and DAPI to halogenated DNAs. Photochem Photobiol. 1990 Jan; 51(1):77-86. PMID: 1689498.
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      17. Brandes R, Rupprecht A, Kearns D. Interaction of water with oriented DNA in the A- and B-form conformations. Biophys J. 1989 Oct; 56(4):683-91. PMID: 2554988.
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      18. Härd T, Sayre MH, Geiduschek EP, Kearns D. A type II DNA-binding protein genetically engineered for fluorescence spectroscopy: the "arm" of transcription factor 1 binds in the DNA grooves. Biochemistry. 1989 Apr 4; 28(7):2813-9. PMID: 2742813.
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      19. Härd T, Hsu V, Sayre MH, Geiduschek EP, Appelt K, Kearns D. Fluorescence studies of a single tyrosine in a type II DNA binding protein. Biochemistry. 1989 Jan 10; 28(1):396-406. PMID: 2706265.
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      20. Brandes R, Vold RR, Kearns D, Rupprecht A. Static disorder and librational motions of the purine bases in films of oriented Li-DNA. J Mol Biol. 1988 Jul 20; 202(2):321-32. PMID: 3172220.
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      21. Behling RW, Rao SN, Kollman P, Kearns D. Molecular mechanics and dynamics calculations on (dA)10.(dT)10 incorporating distance constraints derived from NMR relaxation measurements. Biochemistry. 1987 Jul 28; 26(15):4674-81. PMID: 3663617.
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      22. Assa-Munt N, Denny WA, Leupin W, Kearns D. 1H NMR study of the binding of Bis(acridines) to d(AT)5.d(AT)5. 1. Mode of binding. Biochemistry. 1985 Mar 12; 24(6):1441-9. PMID: 12096751.
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      23. Assa-Munt N, Leupin W, Denny WA, Kearns D. 1H NMR study of the binding of bis(acridines) to d(AT)5.d(AT)5. 2. Dynamic aspects. Biochemistry. 1985 Mar 12; 24(6):1449-60. PMID: 12096754.
        View in: PubMed
      24. Mirau PA, Kearns D. Unusual proton exchange properties of Z-form poly[d(G-C)]. Proc Natl Acad Sci U S A. 1985 Mar; 82(6):1594-8. PMID: 16578783.
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