David Gough

Title(s)	Professor, Bioengineering
School	Vc-academic Affairs
Address	9500 Gilman Drive # La Jolla CA 92093
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Research

research activities and funding

Modeling Mass Transfer to Active Implants for Diabetes
NIH R01DK077101May 15, 2007 - Mar 31, 2010
Role: Principal Investigator

Mass Transfer to Glucose Sensor for Diabetes
NIH R01DK064570Sep 30, 2002 - Mar 31, 2012
Role: Principal Investigator

Validation of Long-Term Glucose Sensor in Tissues
NIH R56DK064570Sep 30, 2002 - Apr 30, 2008
Role: Principal Investigator

INFRASTRUCTURE OF BIOENGINEERING DEVELOPMENT
NIH C06RR017588Sep 15, 2002 - Sep 14, 2004
Role: Principal Investigator

KEY PARAMETERS FOR ARTIFICIAL PANCREAS CONTROLLER
NIH R21DK057109Sep 30, 1999 - Aug 31, 2002
Role: Principal Investigator

TISSUE RESPONSE TO IMPLANTED GLUCOSE SENSOR
NIH R01DK055064Sep 30, 1998 - Sep 29, 2002
Role: Principal Investigator

ESSENTIAL ENDOCRINE PANCREAS
NIH R01DK046307Aug 1, 1995 - Jul 31, 1998
Role: Principal Investigator

DEVELOPMENT OF A GLUCOSE SENSOR FOR DIABETES
NIH R01DK027541Aug 1, 1980 - Mar 31, 1991
Role: Principal Investigator

DEVELOPMENT OF A GLUCOSE SENSOR FOR DIABETES
NIH R01AM027541Aug 1, 1980 - Jan 31, 1987
Role: Principal Investigator

Bibliographic

selected publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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A Compact Battery-Powered rTMS Prototype. Annu Int Conf IEEE Eng Med Biol Soc. 2020 07; 2020:3852-3855. Leung V, Stambaugh M, Abbasi S, Asbeck P, Gough D, Makale M, Murphy KT. PMID: 33018841.

View in: PubMed Mentions: Fields:
Bio Biomedical Engineering
Glucose Monitoring in Individuals With Diabetes Using a Long-Term Implanted Sensor/Telemetry System and Model. IEEE Trans Biomed Eng. 2017 09; 64(9):1982-1993. Lucisano JY, Routh TL, Lin JT, Gough DA. PMID: 27775510; PMCID: PMC5561509.

View in: PubMed Mentions: 17 Fields:
Bio Biomedical Engineering
Translation:Humans
Permeability of subcutaneous tissues surrounding long-term implants to oxygen. Biomaterials. 2014 Sep; 35(29):8287-96. Kumosa LS, Routh TL, Lin JT, Lucisano JY, Gough DA. PMID: 24998180; PMCID: PMC4527688.

View in: PubMed Mentions: 11 Fields:
Bio Biomedical Engineering
Translation:Animals Cells
Hitting is contagious in baseball: evidence from long hitting streaks. PLoS One. 2012; 7(12):e51367. Bock JR, Maewal A, Gough DA. PMID: 23251507; PMCID: PMC3520861.

View in: PubMed Mentions: 3 Fields:
Med Medicine (General)Sci Science
Translation:Humans
Effects of solution concentration on the physicochemical properties of a polymeric anticancer therapeutic. Mol Pharm. 2012 Jan 01; 9(1):37-47. Peng LX, Yu L, Howell SB, Gough DA. PMID: 21988542.

View in: PubMed Mentions: 1 Fields:
Mol Molecular Biology Pha Pharmacology
Translation:Cells
Aggregation properties of a polymeric anticancer therapeutic: a coarse-grained modeling study. J Chem Inf Model. 2011 Dec 27; 51(12):3030-5. Peng LX, Yu L, Howell SB, Gough DA. PMID: 21995420.

View in: PubMed Mentions: 2 Fields:
Che Chemistry Med Medical Informatics
Translation:Cells
Coarse-grained modeling study of nonpeptide RGD ligand density and PEG molecular weight on the conformation of poly(γ-glutamyl-glutamate) paclitaxel conjugates. J Mol Model. 2011 Nov; 17(11):2973-87. Peng LX, Das SK, Yu L, Howell SB, Gough DA. PMID: 21360176; PMCID: PMC3203221.

View in: PubMed Mentions: 1 Fields:
Mol Molecular Biology
Translation:Cells
Characterization of a clinical polymer-drug conjugate using multiscale modeling. Biopolymers. 2010 Nov; 93(11):936-51. Peng LX, Ivetac A, Chaudhari AS, Van S, Zhao G, Yu L, Howell SB, McCammon JA, Gough DA. PMID: 20564048; PMCID: PMC3099131.

View in: PubMed Mentions: 6 Fields:
Bio Biochemistry
Function of an implanted tissue glucose sensor for more than 1 year in animals. Sci Transl Med. 2010 Jul 28; 2(42):42ra53. Gough DA, Kumosa LS, Routh TL, Lin JT, Lucisano JY. PMID: 20668297; PMCID: PMC4528300.

View in: PubMed Mentions: 40 Fields:
Med Medicine (General)Sci Science
Translation:Animals
Novel biodegradable lipid nano complex for siRNA delivery significantly improving the chemosensitivity of human colon cancer stem cells to paclitaxel. J Control Release. 2009 Dec 16; 140(3):277-83. Liu C, Zhao G, Liu J, Ma N, Chivukula P, Perelman L, Okada K, Chen Z, Gough D, Yu L. PMID: 19699770.

View in: PubMed Mentions: 42 Fields:
Pha Pharmacology
Translation:Humans Cells
Preclinical efficacy studies of a novel nanoparticle-based formulation of paclitaxel that out-performs Abraxane. Cancer Chemother Pharmacol. 2010 Apr; 65(5):923-30. Feng Z, Zhao G, Yu L, Gough D, Howell SB. PMID: 19685054; PMCID: PMC2824123.

View in: PubMed Mentions: 17 Fields:
Ant Antineoplastic Agents Neo Neoplasms
Translation:Humans Animals Cells
Blood glucose dynamics. Diabetes Technol Ther. 2008 Apr; 10(2):81-94. Rahaghi FN, Gough DA. PMID: 18260771.

View in: PubMed Mentions: 7 Fields:
End Endocrinology The Therapeutics
Translation:Humans
School-based secondary prevention programmes for preventing violence. Cochrane Database Syst Rev. 2006 Jul 19; (3):CD004606. Mytton J, DiGuiseppi C, Gough D, Taylor R, Logan S. PMID: 16856051; PMCID: PMC8842960.

View in: PubMed Mentions: 46 Fields:
Hea Health Services Research Med Medicine (General)
Translation:Humans
Virtual screen for ligands of orphan G protein-coupled receptors. J Chem Inf Model. 2005 Sep-Oct; 45(5):1402-14. Bock JR, Gough DA. PMID: 16180917.

View in: PubMed Mentions: 22 Fields:
Che Chemistry Med Medical Informatics
Translation:Cells
Variants of the tissue-sensor array window chamber. Am J Physiol Heart Circ Physiol. 2005 Jul; 289(1):H57-65. Makale MT, Chen PC, Gough DA. PMID: 15734882.

View in: PubMed Mentions: 6 Fields:
Car Cardiology Phy Physiology
Translation:Animals
Mass transfer and gas-phase calibration of implanted oxygen sensors. Anal Chem. 2004 Mar 15; 76(6):1773-7. Makale MT, Jablecki MC, Gough DA. PMID: 15018582.

View in: PubMed Mentions: 5 Fields:
Che Chemistry Techniques
Translation:Animals Cells
Tissue window chamber system for validation of implanted oxygen sensors. Am J Physiol Heart Circ Physiol. 2003 Jun; 284(6):H2288-94. Makale MT, Lin JT, Calou RE, Tsai AG, Chen PC, Gough DA. PMID: 12598234.

View in: PubMed Mentions: 6 Fields:
Car Cardiology Phy Physiology
Translation:Animals Cells
Whole-proteome interaction mining. Bioinformatics. 2003 Jan; 19(1):125-34. Bock JR, Gough DA. PMID: 12499302.

View in: PubMed Mentions: 40 Fields:
Com Computational Biology
Translation:Cells
Frequency characterization of blood glucose dynamics. Ann Biomed Eng. 2003 Jan; 31(1):91-7. Gough DA, Kreutz-Delgado K, Bremer TM. PMID: 12572659.

View in: PubMed Mentions: 9 Fields:
Bio Biomedical Engineering
Translation:Humans
A new method to estimate ligand-receptor energetics. Mol Cell Proteomics. 2002 Nov; 1(11):904-10. Bock JR, Gough DA. PMID: 12488466.

View in: PubMed Mentions: 4 Fields:
Bio Biochemistry Cel Cell Biology Mol Molecular Biology
Translation:Cells
School-based violence prevention programs: systematic review of secondary prevention trials. Arch Pediatr Adolesc Med. 2002 Aug; 156(8):752-62. Mytton JA, DiGuiseppi C, Gough DA, Taylor RS, Logan S. PMID: 12144364.

View in: PubMed Mentions: 13 Fields:
Ped Pediatrics
Translation:Humans
Employment and career prospects for bioengineers. Nat Biotechnol. 2002 Jun; 20(6):635-6. Gough D. PMID: 12042874.

View in: PubMed Mentions: Fields:
Bio Biotechnology
Translation:Humans
Predicting protein--protein interactions from primary structure. Bioinformatics. 2001 May; 17(5):455-60. Bock JR, Gough DA. PMID: 11331240.

View in: PubMed Mentions: 130 Fields:
Com Computational Biology
Benchmark data from the literature for evaluation of new glucose sensing technologies. Diabetes Technol Ther. 2001; 3(3):409-18. Bremer TM, Edelman SV, Gough DA. PMID: 11762520.

View in: PubMed Mentions: 1 Fields:
End Endocrinology The Therapeutics
Translation:Humans
Simulations of the frequency response of implantable glucose sensors. Anal Chem. 2000 Apr 15; 72(8):1853-9. Jablecki M, Gough DA. PMID: 10784153.

View in: PubMed Mentions: 11 Fields:
Che Chemistry Techniques
Immobilized glucose oxidase in implantable glucose sensor technology. Diabetes Technol Ther. 2000; 2(3):377-80. Gough DA, Bremer T. PMID: 11467340.

View in: PubMed Mentions: 4 Fields:
End Endocrinology The Therapeutics
Translation:Humans
Is blood glucose predictable from previous values? A solicitation for data. Diabetes. 1999 Mar; 48(3):445-51. Bremer T, Gough DA. PMID: 10078542.

View in: PubMed Mentions: 22 Fields:
End Endocrinology
Translation:Humans
Toward prediction of physiological state signals in sleep apnea. IEEE Trans Biomed Eng. 1998 Nov; 45(11):1332-41. Bock J, Gough DA. PMID: 9805832.

View in: PubMed Mentions: 5 Fields:
Bio Biomedical Engineering
Translation:Humans
Role of xanthine oxidase in hydrogen peroxide production. Free Radic Biol Med. 1998 Oct; 25(6):720-7. Lacy F, Gough DA, Schmid-Schönbein GW. PMID: 9801073.

View in: PubMed Mentions: 20 Fields:
Bio Biochemistry Med Medicine (General)
Advances and prospects in glucose assay technology. Diabetologia. 1997 Jul; 40 Suppl 2:S102-7. Gough DA, Armour JC, Baker DA. PMID: 9248710.

View in: PubMed Mentions: 5 Fields:
End Endocrinology
Translation:Humans Animals
Reservations on the use of error grid analysis for the validation of blood glucose assays. Diabetes Care. 1997 Jun; 20(6):1034-6. Gough DA, Botvinick EL. PMID: 9167120.

View in: PubMed Mentions: 6 Fields:
End Endocrinology
Translation:Humans
Accuracy of least squares designed spatial FIR filters for segmentation of images of fluorescence stained cell nuclei. Cytometry. 1996 Dec 01; 25(4):303-16. Price JH, Hunter EA, Gough DA. PMID: 8946137.

View in: PubMed Mentions: 6 Fields:
Cel Cell Biology
Translation:Animals Cells
Dynamic delay and maximal dynamic error in continuous biosensors. Anal Chem. 1996 Apr 15; 68(8):1292-7. Baker DA, Gough DA. PMID: 8651496.

View in: PubMed Mentions: 7 Fields:
Che Chemistry Techniques
Development of the implantable glucose sensor. What are the prospects and why is it taking so long? Diabetes. 1995 Sep; 44(9):1005-9. Gough DA, Armour JC. PMID: 7657021.

View in: PubMed Mentions: 15 Fields:
End Endocrinology
Translation:Humans
Comparison of phase-contrast and fluorescence digital autofocus for scanning microscopy. Cytometry. 1994 Aug 01; 16(4):283-97. Price JH, Gough DA. PMID: 7988291.

View in: PubMed Mentions: 6 Fields:
Cel Cell Biology
Translation:Animals Cells
Dynamic concentration challenges for biosensor characterization. Biosens Bioelectron. 1993; 8(9-10):433-41. Baker DA, Gough DA. PMID: 8311939.

View in: PubMed Mentions: 1 Fields:
Bio Biotechnology
Translation:Humans Animals
Design and validation of the transparent oxygen sensor array. IEEE Trans Biomed Eng. 1991 May; 38(5):476-82. Sargent BJ, Gough DA. PMID: 1874530.

View in: PubMed Mentions: Fields:
Bio Biomedical Engineering
Translation:Animals
Application of chronic intravascular blood glucose sensor in dogs. Diabetes. 1990 Dec; 39(12):1519-26. Armour JC, Lucisano JY, McKean BD, Gough DA. PMID: 2245876.

View in: PubMed Mentions: 20 Fields:
End Endocrinology
Translation:Animals
Physiological preparation for studying the response of subcutaneously implanted glucose and oxygen sensors. J Biomed Eng. 1989 Sep; 11(5):362-8. Ertefai S, Gough DA. PMID: 2677523.

View in: PubMed Mentions: 10 Fields:
Bio Biomedical Engineering
Translation:Animals
A telemetry-instrumentation system for chronically implanted glucose and oxygen sensors. IEEE Trans Biomed Eng. 1988 Jul; 35(7):526-32. McKean BD, Gough DA. PMID: 3209214.

View in: PubMed Mentions: 3 Fields:
Bio Biomedical Engineering
Translation:Humans Animals
Transient response of the two-dimensional glucose sensor. Anal Chem. 1988 Jul 01; 60(13):1272-81. Lucisano JY, Gough DA. PMID: 3213947.

View in: PubMed Mentions: Fields:
Che Chemistry Techniques
Issues related to in vitro operation of potentially implantable enzyme electrode glucose sensors. Horm Metab Res Suppl. 1988; 20:30-3. Gough DA. PMID: 3074035.

View in: PubMed Mentions: 1 Fields:
End Endocrinology Met Metabolism
Transient response of an enzyme electrode sensor for glucose. Anal Chem. 1987 Oct 01; 59(19):2339-44. Tse PH, Gough DA. PMID: 3674445.

View in: PubMed Mentions: 1 Fields:
Che Chemistry Techniques
Determination of the intrinsic kinetic constants of immobilized glucose oxidase and catalase. Biotechnol Bioeng. 1987 Apr; 29(6):696-704. Tse PH, Leypoldt JK, Gough DA. PMID: 18576504.

View in: PubMed Mentions: 3 Fields:
Bio Biomedical Engineering Bio Biotechnology
Time-dependent inactivation of immobilized glucose oxidase and catalase. Biotechnol Bioeng. 1987 Apr; 29(6):705-13. Tse PH, Gough DA. PMID: 18576505.

View in: PubMed Mentions: 8 Fields:
Bio Biomedical Engineering Bio Biotechnology
In vitro stability of an oxygen sensor. Anal Chem. 1987 Mar 01; 59(5):736-9. Lucisano JY, Armour JC, Gough DA. PMID: 3565773.

View in: PubMed Mentions: 4 Fields:
Che Chemistry Techniques
Short-term in vivo operation of a glucose sensor. ASAIO Trans. 1986 Jul-Sep; 32(1):148-50. Gough DA, Armour JC, Lucisano JY, McKean BD. PMID: 3778702.

View in: PubMed Mentions: Fields:
Tra Transplantation
Translation:Animals
A transparent oxygen sensor array. Ann Biomed Eng. 1986; 14(2):153-61. Gough DA, Sargent BJ, Tse PH. PMID: 3740567.

View in: PubMed Mentions: Fields:
Bio Biomedical Engineering
Two-dimensional enzyme electrode sensor for glucose. Anal Chem. 1985 Oct; 57(12):2351-7. Gough DA, Lucisano JY, Tse PH. PMID: 4061843.

View in: PubMed Mentions: 18 Fields:
Che Chemistry Techniques
Translation:Cells
Model of a two-substrate enzyme electrode for glucose. Anal Chem. 1984 Dec; 56(14):2896-904. Leypoldt JK, Gough DA. PMID: 6524662.

View in: PubMed Mentions: 7 Fields:
Che Chemistry Techniques
Translation:Cells
Diffusion and the limiting substrate in two-substrate immobilized enzyme systems. Biotechnol Bioeng. 1982 Dec; 24(12):2705-19. Leypoldt JK, Gough DA. PMID: 18546248.

View in: PubMed Mentions: 3 Fields:
Bio Biomedical Engineering Bio Biotechnology
The composition and optical rotary dispersion of bovine aqueous humor. Diabetes Care. 1982 May-Jun; 5(3):266-70. Gough DA. PMID: 7172993.

View in: PubMed Mentions: Fields:
End Endocrinology
Translation:Animals
Progress toward a potentially implantable, enzyme-based glucose sensor. Diabetes Care. 1982 May-Jun; 5(3):190-8. Gough DA, Leypoldt JK, Armour JC. PMID: 7172982.

View in: PubMed Mentions: 4 Fields:
End Endocrinology
The status of electrochemical sensors for in vivo glucose monitoring. Horm Metab Res. 1977; Suppl 7:10-22. Gough DA, Aisenberg S, Colton CK, Giner J, Soeldner JS. PMID: 326652.

View in: PubMed Mentions: 3 Fields:
End Endocrinology Met Metabolism
Translation:Humans Cells
Enzyme electrodes. Science. 1973 Apr 27; 180(4084):380-4. Gough DA, Andrade JD. PMID: 4573391.

View in: PubMed Mentions: 3 Fields:
Sci Science
Translation:Cells