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David Gough

TitleProfessor
InstitutionUniversity of California San Diego
DepartmentBioengineering
Address9500 Gilman Drive #0412
La Jolla CA 92093
Phone858-822-3446
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    Collapse Research 
    Collapse Research Activities and Funding
    Modeling Mass Transfer to Active Implants for Diabetes
    NIH/NIDDK R01DK077101May 15, 2007 - Mar 31, 2010
    Role: Principal Investigator
    Mass Transfer to Glucose Sensor for Diabetes
    NIH/NIDDK R01DK064570Sep 30, 2002 - Mar 31, 2012
    Role: Principal Investigator
    Validation of Long-Term Glucose Sensor in Tissues
    NIH/NIDDK R56DK064570Sep 30, 2002 - Apr 30, 2008
    Role: Principal Investigator
    INFRASTRUCTURE OF BIOENGINEERING DEVELOPMENT
    NIH/NCRR C06RR017588Sep 15, 2002 - Sep 14, 2004
    Role: Principal Investigator
    KEY PARAMETERS FOR ARTIFICIAL PANCREAS CONTROLLER
    NIH/NIDDK R21DK057109Sep 30, 1999 - Aug 31, 2002
    Role: Principal Investigator
    TISSUE RESPONSE TO IMPLANTED GLUCOSE SENSOR
    NIH/NIDDK R01DK055064Sep 30, 1998 - Sep 29, 2002
    Role: Principal Investigator
    ESSENTIAL ENDOCRINE PANCREAS
    NIH/NIDDK R01DK046307Aug 1, 1995 - Jul 31, 1998
    Role: Principal Investigator
    DEVELOPMENT OF A GLUCOSE SENSOR FOR DIABETES
    NIH/NIDDK R01DK027541Aug 1, 1980 - Mar 31, 1991
    Role: Principal Investigator
    DEVELOPMENT OF A GLUCOSE SENSOR FOR DIABETES
    NIH/NIADDK R01AM027541Aug 1, 1980 - Jan 31, 1987
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Lucisano JY, Routh TL, Lin JT, Gough D. Glucose Monitoring in Individuals With Diabetes Using a Long-Term Implanted Sensor/Telemetry System and Model. IEEE Trans Biomed Eng. 2017 09; 64(9):1982-1993. PMID: 27775510.
      View in: PubMed
    2. Kumosa LS, Routh TL, Lin JT, Lucisano JY, Gough D. Permeability of subcutaneous tissues surrounding long-term implants to oxygen. Biomaterials. 2014 Sep; 35(29):8287-96. PMID: 24998180; PMCID: PMC4527688.
      View in: PubMed, PubMed Central
    3. Bock JR, Maewal A, Gough D. Hitting is contagious in baseball: evidence from long hitting streaks. PLoS One. 2012; 7(12):e51367. PMID: 23251507; PMCID: PMC3520861.
      View in: PubMed, PubMed Central
    4. Peng LX, Yu L, Howell SB, Gough D. Effects of solution concentration on the physicochemical properties of a polymeric anticancer therapeutic. Mol Pharm. 2012 Jan 01; 9(1):37-47. PMID: 21988542.
      View in: PubMed
    5. Peng LX, Yu L, Howell SB, Gough D. Aggregation properties of a polymeric anticancer therapeutic: a coarse-grained modeling study. J Chem Inf Model. 2011 Dec 27; 51(12):3030-5. PMID: 21995420.
      View in: PubMed
    6. Peng LX, Das SK, Yu L, Howell SB, Gough D. Coarse-grained modeling study of nonpeptide RGD ligand density and PEG molecular weight on the conformation of poly(?-glutamyl-glutamate) paclitaxel conjugates. J Mol Model. 2011 Nov; 17(11):2973-87. PMID: 21360176; PMCID: PMC3203221.
      View in: PubMed, PubMed Central
    7. Peng LX, Ivetac A, Chaudhari AS, Van S, Zhao G, Yu L, Howell SB, McCammon JA, Gough D. Characterization of a clinical polymer-drug conjugate using multiscale modeling. Biopolymers. 2010 Nov; 93(11):936-51. PMID: 20564048; PMCID: PMC3099131.
      View in: PubMed, PubMed Central
    8. Gough D, Kumosa LS, Routh TL, Lin JT, Lucisano JY. Function of an implanted tissue glucose sensor for more than 1 year in animals. Sci Transl Med. 2010 Jul 28; 2(42):42ra53. PMID: 20668297; PMCID: PMC4528300.
      View in: PubMed, PubMed Central
    9. Liu C, Zhao G, Liu J, Ma N, Chivukula P, Perelman L, Okada K, Chen Z, Gough D, Yu L. Novel biodegradable lipid nano complex for siRNA delivery significantly improving the chemosensitivity of human colon cancer stem cells to paclitaxel. J Control Release. 2009 Dec 16; 140(3):277-83. PMID: 19699770.
      View in: PubMed
    10. Feng Z, Zhao G, Yu L, Gough D, Howell SB. Preclinical efficacy studies of a novel nanoparticle-based formulation of paclitaxel that out-performs Abraxane. Cancer Chemother Pharmacol. 2010 Apr; 65(5):923-30. PMID: 19685054; PMCID: PMC2824123.
      View in: PubMed, PubMed Central
    11. Rahaghi FN, Gough D. Blood glucose dynamics. Diabetes Technol Ther. 2008 Apr; 10(2):81-94. PMID: 18260771.
      View in: PubMed
    12. Bock JR, Gough D. Virtual screen for ligands of orphan G protein-coupled receptors. J Chem Inf Model. 2005 Sep-Oct; 45(5):1402-14. PMID: 16180917.
      View in: PubMed
    13. Makale MT, Chen PC, Gough D. Variants of the tissue-sensor array window chamber. Am J Physiol Heart Circ Physiol. 2005 Jul; 289(1):H57-65. PMID: 15734882.
      View in: PubMed
    14. Makale MT, Jablecki MC, Gough D. Mass transfer and gas-phase calibration of implanted oxygen sensors. Anal Chem. 2004 Mar 15; 76(6):1773-7. PMID: 15018582.
      View in: PubMed
    15. Makale MT, Lin JT, Calou RE, Tsai AG, Chen PC, Gough D. Tissue window chamber system for validation of implanted oxygen sensors. Am J Physiol Heart Circ Physiol. 2003 Jun; 284(6):H2288-94. PMID: 12598234.
      View in: PubMed
    16. Bock JR, Gough D. Whole-proteome interaction mining. Bioinformatics. 2003 Jan; 19(1):125-34. PMID: 12499302.
      View in: PubMed
    17. Gough D, Kreutz-Delgado K, Bremer TM. Frequency characterization of blood glucose dynamics. Ann Biomed Eng. 2003 Jan; 31(1):91-7. PMID: 12572659.
      View in: PubMed
    18. Bock JR, Gough D. A new method to estimate ligand-receptor energetics. Mol Cell Proteomics. 2002 Nov; 1(11):904-10. PMID: 12488466.
      View in: PubMed
    19. Mytton JA, DiGuiseppi C, Gough D, Taylor RS, Logan S. School-based violence prevention programs: systematic review of secondary prevention trials. Arch Pediatr Adolesc Med. 2002 Aug; 156(8):752-62. PMID: 12144364.
      View in: PubMed
    20. Gough D. Employment and career prospects for bioengineers. Nat Biotechnol. 2002 Jun; 20(6):635-6. PMID: 12042874.
      View in: PubMed
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