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    Daniel Kripke

    TitleSenate Emeritus
    SchoolUniversity of California, San Diego
    DepartmentPsychiatry
    Address9500 Gilman Drive #0603
    CA La Jolla 92093
    Phone858-222-2934
    vCardDownload vCard

      Collapse Overview 
      Collapse Overview

      Biography

      Educated at Harvard College, P&S, the US Air Force 6571st Aeromedical Research Lab and an Albert Einstein residency, Dr. Kripke has spent over 30 years at UCSD. He developed the first sleep clinic in the region and new technologies for home sleep monitoring and wrist actigraphy. He did the first controlled trial of bright light treatment at the San Diego VA Medical Center in 1981. He has been concerned with the community prevalence of sleep apnea, particularly with aging, and the excess mortality associated with sleep >= 8 hours and with sleeping pills. With development of the Circadian Pacemaker Laboratory in the Sam and Rose Stein Clinical Research Building, they have been doing studies in basic and applied human chronobiology with a view towards understanding affective disorders.

      Research Interests

      Current studies focus on bright light treatment of depression, the clinical efficacy and the underlying mechanisms. They are also interested in the circadian phase-response to bright light and exercise stimuli and the consequences for melatonin regulation. Light’s roll in photoperiodic regulation in humans is a long-term theme. Preliminary studies are examining how genetic variations in circadian clocks may influence clinical pathology.


      Collapse Research 
      Collapse Research Activities and Funding
      Light Stimulation of Luteinizing Hormone
      NIH/NIMH R01MH068545Sep 1, 2004 - Aug 31, 2008
      Role: Principal Investigator
      GENETIC VARIANTS IN CIRCADIAN RHYTHM SLEEP DISORDERS
      NIH/NHLBI R01HL071123Apr 1, 2004 - Jun 30, 2007
      Role: Principal Investigator
      GENETIC VARIANTS IN CIRCADIAN RHYTHM SLEEP DISORDERS
      NIH/NHLBI R56HL071123Jul 1, 2002 - Jun 30, 2009
      Role: Principal Investigator
      PHASE RESPONSE CURVES FOR EXERCISE AND BRIGHT LIGHT
      NIH/NHLBI R01HL061280Aug 1, 1999 - Jul 31, 2004
      Role: Principal Investigator
      VERIFICATION OF CIRCADIAN ABNORMALITIES IN AGING
      NIH/NIA R01AG015763Sep 1, 1998 - Aug 31, 2004
      Role: Principal Investigator
      EMF EFFECTS ON MELATONIN AMONG AGING VOLUNTEERS
      NIH/NIEHS R03ES008930Jan 15, 1997 - Jun 30, 1999
      Role: Principal Investigator
      VALIDATION AND EXPLORATION OF SLEEP AND MOOD PREDICTORS
      NIH/NHLBI R01HL055983Aug 1, 1995 - Jul 31, 2000
      Role: Principal Investigator
      ILLUMINATION IN HUMAN AGING: SLEEP AND MOOD EFFECTS
      NIH/NIA R01AG012364Sep 30, 1994 - Apr 30, 2006
      Role: Principal Investigator
      BEHAVIORAL/LIGHT EFFECTS ON MENSTRUAL CYCLE REGULATION
      NIH/NIMH R03MH051820May 1, 1994 - Apr 30, 1997
      Role: Principal Investigator
      AGE RELATED PREVALENCE OF SLEEP RESPIRATORY DISTURBANCES
      NIH/NHLBI R01HL040930Apr 1, 1990 - Mar 31, 1996
      Role: Principal Investigator
      PHOTOPERIODIC TREATMENT OF DEPRESSION
      NIH/NIMH R01MH038822Mar 1, 1984 - Jun 30, 1988
      Role: Principal Investigator
      PREVALENCE OF SLEEP APNEA IN AN AGED POPULATION
      NIH/NIA R01AG002711Apr 1, 1981 - Mar 31, 2001
      Role: Co-Principal Investigator
      BIO-OSCILLATOR EFFECTS ON MENTAL FUNCTION
      NIH/NIMH K05MH000117Jan 1, 1977 - Dec 31, 1996
      Role: Principal Investigator
      BIO-OSCILLATOR EFFECTS ON MENTAL FUNCTION
      NIH/NIMH K02MH000117Jan 1, 1977 - Dec 31, 1986
      Role: Principal Investigator

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Kripke D. What do hypnotics cost hospitals and healthcare? F1000Res. 2017; 6:542. PMID: 28781755.
        View in: PubMed
      2. Moon JH, Cho CH, Son GH, Geum D, Chung S, Kim H, Kang SG, Park YM, Yoon HK, Kim L, Jee HJ, An H, Kripke D, Lee HJ. Advanced Circadian Phase in Mania and Delayed Circadian Phase in Mixed Mania and Depression Returned to Normal after Treatment of Bipolar Disorder. EBioMedicine. 2016 Sep; 11:285-295. PMID: 27543154.
        View in: PubMed
      3. Kripke D. Hypnotic drug risks of mortality, infection, depression, and cancer: but lack of benefit. F1000Res. 2016; 5:918. PMID: 27303633; PMCID: PMC4890308.
        View in: PubMed, PubMed Central
      4. Kripke D. When our body clocks run late: does it make us depressed? Ann Transl Med. 2016 May; 4(9):178. PMID: 27275491; PMCID: PMC4876263.
        View in: PubMed, PubMed Central
      5. Kripke D. Mortality Risk of Hypnotics: Strengths and Limits of Evidence. Drug Saf. 2016 Feb; 39(2):93-107. PMID: 26563222.
        View in: PubMed
      6. Kripke D. I petitioned the FDA to restrict hypnotics: here is why. Sleep Med. 2016 Jul; 23:119-120. PMID: 26924532.
        View in: PubMed
      7. Youngstedt SD, Goff EE, Reynolds AM, Kripke D, Irwin MR, Bootzin RR, Khan N, Jean-Louis G. Has adult sleep duration declined over the last 50+ years? Sleep Med Rev. 2016 Aug; 28:69-85. PMID: 26478985; PMCID: PMC4769964 [Available on 08/01/17].
        View in: PubMed, PubMed Central
      8. Kripke D. Is suvorexant a better choice than alternative hypnotics? F1000Res. 2015; 4:456. PMID: 26594338; PMCID: PMC4648222.
        View in: PubMed, PubMed Central
      9. Dawson A, Loving RT, Gordon RM, Abel SL, Loewy D, Kripke D, Kline LE. Type III home sleep testing versus pulse oximetry: is the respiratory disturbance index better than the oxygen desaturation index to predict the apnoea-hypopnoea index measured during laboratory polysomnography? BMJ Open. 2015 Jun 30; 5(6):e007956. PMID: 26129636; PMCID: PMC4486950.
        View in: PubMed, PubMed Central
      10. Kripke D. Do hypnotic drugs cause cancer, like cigarettes? Sleep Med. 2015 Dec; 16(12):1550-1. PMID: 26210392.
        View in: PubMed
      11. Kripke D, Elliott JA, Welsh DK, Youngstedt SD. Photoperiodic and circadian bifurcation theories of depression and mania. F1000Res. 2015; 4:107. PMID: 26180634; PMCID: PMC4490783.
        View in: PubMed, PubMed Central
      12. Kripke D. A breakthrough treatment for major depression. J Clin Psychiatry. 2015 May; 76(5):e660-1. PMID: 26035202.
        View in: PubMed
      13. Kripke D, Kline LE, Nievergelt CM, Murray SS, Shadan FF, Dawson A, Poceta JS, Cronin J, Jamil SM, Tranah GJ, Loving RT, Grizas AP, Hahn EK. Genetic variants associated with sleep disorders. Sleep Med. 2015 Feb; 16(2):217-24. PMID: 25660813; PMCID: PMC4352103.
        View in: PubMed, PubMed Central
      14. Kripke D, Klimecki WT, Nievergelt CM, Rex KM, Murray SS, Shekhtman T, Tranah GJ, Loving RT, Lee HJ, Rhee MK, Shadan FF, Poceta JS, Jamil SM, Kline LE, Kelsoe JR. Circadian polymorphisms in night owls, in bipolars, and in non-24-hour sleep cycles. Psychiatry Investig. 2014 Oct; 11(4):345-62. PMID: 25395965; PMCID: PMC4225198.
        View in: PubMed, PubMed Central
      15. Kripke D. "Rebound" is not an appropriate criterion for withdrawal insomnia. Sleep Med. 2014 Dec; 15(12):1594. PMID: 25441753.
        View in: PubMed
      16. Kripke D. Hypnotics cause insomnia: evidence from clinical trials. Sleep Med. 2014 Sep; 15(9):1168-9. PMID: 25152199.
        View in: PubMed
      17. Kripke D, Langer RD. Evidence for harm, comment on ‘Use of benzodiazepines or benzodiazepine related drugs and the risk of cancer: a population-based case-control study’. Br J Clin Pharmacol. 2014 Jul; 78(1):186-7. PMID: 25083532; PMCID: PMC4168393.
        View in: PubMed, PubMed Central
      18. Meliska CJ, Martínez LF, López AM, Sorenson DL, Nowakowski S, Kripke D, Elliott J, Parry BL. Antepartum depression severity is increased during seasonally longer nights: relationship to melatonin and cortisol timing and quantity. Chronobiol Int. 2013 Nov; 30(9):1160-73. PMID: 23998286; PMCID: PMC4041493.
        View in: PubMed, PubMed Central
      19. Youngstedt SD, Jean-Louis G, Bootzin RR, Kripke D, Cooper J, Dean LR, Catao F, James S, Vining C, Williams NJ, Irwin MR. Chronic moderate sleep restriction in older long sleepers and older average duration sleepers: a randomized controlled trial. Contemp Clin Trials. 2013 Sep; 36(1):175-86. PMID: 23811325; PMCID: PMC3860282.
        View in: PubMed, PubMed Central
      20. Kripke D, Nievergelt CM, Tranah GJ, Murray SS, Rex KM, Grizas AP, Hahn EK, Lee HJ, Kelsoe JR, Kline LE. FMR1, circadian genes and depression: suggestive associations or false discovery? J Circadian Rhythms. 2013 Mar 23; 11(1):3. PMID: 23521777; PMCID: PMC3627611.
        View in: PubMed, PubMed Central
      21. Rhee MK, Lee HJ, Rex KM, Kripke D. Evaluation of two circadian rhythm questionnaires for screening for the delayed sleep phase disorder. Psychiatry Investig. 2012 Sep; 9(3):236-44. PMID: 22993522; PMCID: PMC3440472.
        View in: PubMed, PubMed Central
      22. Lee HJ, Woo HG, Greenwood TA, Kripke D, Kelsoe JR. A genome-wide association study of seasonal pattern mania identifies NF1A as a possible susceptibility gene for bipolar disorder. J Affect Disord. 2013 Feb 20; 145(2):200-7. PMID: 22925353.
        View in: PubMed
      23. Kripke D, Langer RD, Kline LE. Do no harm: not even to some degree. J Clin Sleep Med. 2012 Aug 15; 8(4):353-4. PMID: 22893763; PMCID: PMC3407251.
        View in: PubMed, PubMed Central
      24. Kripke D, Langer RD, Kline LE. Hypnotics' association with mortality or cancer: a matched cohort study. BMJ Open. 2012; 2(1):e000850. PMID: 22371848; PMCID: PMC3293137.
        View in: PubMed, PubMed Central
      25. Kripke D, Nievergelt CM, Tranah GJ, Murray SS, McCarthy MJ, Rex KM, Parimi N, Kelsoe JR. Polymorphisms in melatonin synthesis pathways: possible influences on depression. J Circadian Rhythms. 2011 Aug 09; 9:8. PMID: 21827647; PMCID: PMC3177871.
        View in: PubMed, PubMed Central
      26. Kripke D. Bright light treatment reduces symptoms in older adults with non-seasonal major depression. Evid Based Ment Health. 2011 Aug; 14(3):75. PMID: 21764874.
        View in: PubMed
      27. Lee HJ, Rex KM, Nievergelt CM, Kelsoe JR, Kripke D. Delayed sleep phase syndrome is related to seasonal affective disorder. J Affect Disord. 2011 Oct; 133(3):573-9. PMID: 21601293; PMCID: PMC3163003.
        View in: PubMed, PubMed Central
      28. Kripke D. Is insomnia associated with mortality? Sleep. 2011 May 01; 34(5):555; author reply 557-8. PMID: 21532944; PMCID: PMC3079930.
        View in: PubMed, PubMed Central
      29. Kripke D, Hahn EK, Grizas AP, Wadiak KH, Loving RT, Poceta JS, Shadan FF, Cronin JW, Kline LE. Wrist actigraphic scoring for sleep laboratory patients: algorithm development. J Sleep Res. 2010 Dec; 19(4):612-9. PMID: 20408923.
        View in: PubMed
      30. Kripke D. Illumination and mood. Psychopharmacology (Berl). 2011 Feb; 213(4):833. PMID: 20953587; PMCID: PMC3033512.
        View in: PubMed, PubMed Central
      31. Kripke D, Langer RD, Elliott JA, Klauber MR, Rex KM. Mortality related to actigraphic long and short sleep. Sleep Med. 2011 Jan; 12(1):28-33. PMID: 20870457; PMCID: PMC3010336.
        View in: PubMed, PubMed Central
      32. Kripke D, Elliott JA, Youngstedt SD, Parry BL, Hauger RL, Rex KM. Weak evidence of bright light effects on human LH and FSH. J Circadian Rhythms. 2010 May 11; 8:5. PMID: 20459826; PMCID: PMC2885316.
        View in: PubMed, PubMed Central
      33. Youngstedt SD, Kripke D, Kline CE, Zielinski MR, Bogan RK. Lack of impairment in glucose tolerance: support for further investigation of sleep restriction in older long sleepers. J Sleep Res. 2010 Mar; 19(1 Pt 1):116-7. PMID: 20470263.
        View in: PubMed
      34. Kripke D, Shadan FF, Dawson A, Cronin JW, Jamil SM, Grizas AP, Koziol JA, Kline LE. Genotyping sleep disorders patients. Psychiatry Investig. 2010 Mar; 7(1):36-42. PMID: 20396431; PMCID: PMC2848776.
        View in: PubMed, PubMed Central
      35. Kline CE, Zielinski MR, Devlin TM, Kripke D, Bogan RK, Youngstedt SD. Self-reported long sleep in older adults is closely related to objective time in bed. Sleep Biol Rhythms. 2010 Jan; 8(1):42-51. PMID: 25210491.
        View in: PubMed
      36. Grandner MA, Kripke D, Naidoo N, Langer RD. Relationships among dietary nutrients and subjective sleep, objective sleep, and napping in women. Sleep Med. 2010 Feb; 11(2):180-4. PMID: 20005774; PMCID: PMC2819566.
        View in: PubMed, PubMed Central
      37. Youngstedt SD, Kline CE, Zielinski MR, Kripke D, Devlin TM, Bogan RK, Wilcox S, Hardin JW. Tolerance of chronic 90-minute time-in-bed restriction in older long sleepers. Sleep. 2009 Nov; 32(11):1467-79. PMID: 19928386; PMCID: PMC2768953.
        View in: PubMed, PubMed Central
      38. Joya FL, Kripke D, Loving RT, Dawson A, Kline LE. Meta-analyses of hypnotics and infections: eszopiclone, ramelteon, zaleplon, and zolpidem. J Clin Sleep Med. 2009 Aug 15; 5(4):377-83. PMID: 19968019; PMCID: PMC2725260.
        View in: PubMed, PubMed Central
      39. Björkstén KS, Kripke D, Bjerregaard P. Accentuation of suicides but not homicides with rising latitudes of Greenland in the sunny months. BMC Psychiatry. 2009 May 08; 9:20. PMID: 19422728; PMCID: PMC2685778.
        View in: PubMed, PubMed Central
      40. Kripke D. Do hypnotics cause death and cancer? The burden of proof. Sleep Med. 2009 Mar; 10(3):275-6. PMID: 19269891.
        View in: PubMed
      41. Kripke D, Nievergelt CM, Joo E, Shekhtman T, Kelsoe JR. Circadian polymorphisms associated with affective disorders. J Circadian Rhythms. 2009 Jan 23; 7:2. PMID: 19166596; PMCID: PMC2661876.
        View in: PubMed, PubMed Central
      42. Chae KY, Kripke D, Poceta JS, Shadan F, Jamil SM, Cronin JW, Kline LE. Evaluation of immobility time for sleep latency in actigraphy. Sleep Med. 2009 Jun; 10(6):621-5. PMID: 19103508.
        View in: PubMed
      43. Dawson A, Abel SL, Loving RT, Dailey G, Shadan FF, Cronin JW, Kripke D, Kline LE. CPAP therapy of obstructive sleep apnea in type 2 diabetics improves glycemic control during sleep. J Clin Sleep Med. 2008 Dec 15; 4(6):538-42. PMID: 19110882; PMCID: PMC2603530.
        View in: PubMed, PubMed Central
      44. Parry BL, Meliska CJ, Sorenson DL, Lopez AM, Martinez LF, Nowakowski S, Elliott JA, Hauger RL, Kripke D. Plasma melatonin circadian rhythm disturbances during pregnancy and postpartum in depressed women and women with personal or family histories of depression. Am J Psychiatry. 2008 Dec; 165(12):1551-8. PMID: 18829869; PMCID: PMC3038788.
        View in: PubMed, PubMed Central
      45. Kripke D. Possibility that certain hypnotics might cause cancer in skin. J Sleep Res. 2008 Sep; 17(3):245-50. PMID: 18844818.
        View in: PubMed
      46. Zielinski MR, Kline CE, Kripke D, Bogan RK, Youngstedt SD. No effect of 8-week time in bed restriction on glucose tolerance in older long sleepers. J Sleep Res. 2008 Dec; 17(4):412-9. PMID: 18691360; PMCID: PMC3244074.
        View in: PubMed, PubMed Central
      47. Kripke D, Rex KM, Ancoli-Israel S, Nievergelt CM, Klimecki W, Kelsoe JR. Delayed sleep phase cases and controls. J Circadian Rhythms. 2008 Apr 29; 6:6. PMID: 18445295; PMCID: PMC2391143.
        View in: PubMed, PubMed Central
      48. Poceta JS, Parsons L, Engelland S, Kripke D. Circadian rhythm of CSF monoamines and hypocretin-1 in restless legs syndrome and Parkinson's disease. Sleep Med. 2009 Jan; 10(1):129-33. PMID: 18207455.
        View in: PubMed
      49. Kripke D. Who should sponsor sleep disorders pharmaceutical trials? J Clin Sleep Med. 2007 Dec 15; 3(7):671-3. PMID: 18198797; PMCID: PMC2556906.
        View in: PubMed, PubMed Central
      50. Park DH, Kripke D, Louis GJ, Elliott JA, Klauber MR, Rex KM, Tuunainen A, Langer RD. Self-reported sleep latency in postmenopausal women. J Korean Med Sci. 2007 Dec; 22(6):1007-14. PMID: 18162715; PMCID: PMC2694625.
        View in: PubMed, PubMed Central
      51. Youngstedt SD, Kripke D. Does bright light have an anxiolytic effect? - an open trial. BMC Psychiatry. 2007 Oct 30; 7:62. PMID: 17971237; PMCID: PMC2194679.
        View in: PubMed, PubMed Central
      52. Kripke D. Greater incidence of depression with hypnotic use than with placebo. BMC Psychiatry. 2007 Aug 21; 7:42. PMID: 17711589; PMCID: PMC1994947.
        View in: PubMed, PubMed Central
      53. Kripke D, Elliott JA, Youngstedt SD, Rex KM. Circadian phase response curves to light in older and young women and men. J Circadian Rhythms. 2007 Jul 10; 5:4. PMID: 17623102; PMCID: PMC1988787.
        View in: PubMed, PubMed Central
      54. Park DH, Kripke D, Cole RJ. More prominent reactivity in mood than activity and sleep induced by differential light exposure due to seasonal and local differences. Chronobiol Int. 2007; 24(5):905-20. PMID: 17994345.
        View in: PubMed
      55. Lee AC, Mosaed S, Weinreb RN, Kripke D, Liu JH. Effect of laser trabeculoplasty on nocturnal intraocular pressure in medically treated glaucoma patients. Ophthalmology. 2007 Apr; 114(4):666-70. PMID: 17188360.
        View in: PubMed
      56. Grandner MA, Kripke D, Yoon IY, Youngstedt SD. Criterion validity of the Pittsburgh Sleep Quality Index: Investigation in a non-clinical sample. Sleep Biol Rhythms. 2006 Jun; 4(2):129-139. PMID: 22822303.
        View in: PubMed
      57. Sit AJ, Weinreb RN, Crowston JG, Kripke D, Liu JH. Sustained effect of travoprost on diurnal and nocturnal intraocular pressure. Am J Ophthalmol. 2006 Jun; 141(6):1131-3. PMID: 16765686.
        View in: PubMed
      58. Grandner MA, Kripke D, Langer RD. Light exposure is related to social and emotional functioning and to quality of life in older women. Psychiatry Res. 2006 Jun 30; 143(1):35-42. PMID: 16725207; PMCID: PMC3685148.
        View in: PubMed, PubMed Central
      59. Kripke D, Kline LE, Shadan FF, Dawson A, Poceta JS, Elliott JA. Melatonin effects on luteinizing hormone in postmenopausal women: a pilot clinical trial NCT00288262. BMC Womens Health. 2006 May 16; 6:8. PMID: 16704731; PMCID: PMC1481506.
        View in: PubMed, PubMed Central
      60. Nievergelt CM, Kripke D, Barrett TB, Burg E, Remick RA, Sadovnick AD, McElroy SL, Keck PE, Schork NJ, Kelsoe JR. Suggestive evidence for association of the circadian genes PERIOD3 and ARNTL with bipolar disorder. Am J Med Genet B Neuropsychiatr Genet. 2006 Apr 05; 141B(3):234-41. PMID: 16528748; PMCID: PMC2651679.
        View in: PubMed, PubMed Central
      61. Kripke D, Tuunainen A, Endo T. Benefits of light treatment for depression. Am J Psychiatry. 2006 Jan; 163(1):162-3; author reply 163. PMID: 16390913.
        View in: PubMed
      62. Jean-Louis G, Kripke D, Elliott JA, Zizi F, Wolintz AH, Lazzaro DR. Daily illumination exposure and melatonin: influence of ophthalmic dysfunction and sleep duration. J Circadian Rhythms. 2005 Dec 01; 3:13. PMID: 16321164; PMCID: PMC1325258.
        View in: PubMed, PubMed Central
      63. Loving RT, Kripke D, Elliott JA, Knickerbocker NC, Grandner MA. Bright light treatment of depression for older adults [ISRCTN55452501]. BMC Psychiatry. 2005 Nov 09; 5:41. PMID: 16283925; PMCID: PMC1298312.
        View in: PubMed, PubMed Central
      64. Loving RT, Kripke D, Knickerbocker NC, Grandner MA. Bright green light treatment of depression for older adults [ISRCTN69400161]. BMC Psychiatry. 2005 Nov 09; 5:42. PMID: 16283926; PMCID: PMC1309618.
        View in: PubMed, PubMed Central
      65. Youngstedt SD, Kripke D, Elliott JA, Rex KM. Circadian phase-shifting effects of a laboratory environment: a clinical trial with bright and dim light. J Circadian Rhythms. 2005 Sep 09; 3:11. PMID: 16153301; PMCID: PMC1224862.
        View in: PubMed, PubMed Central
      66. Kripke D. Selective publication. Sleep. 2005 Mar; 28(3):370; author reply 371-2. PMID: 16173660.
        View in: PubMed
      67. Nievergelt CM, Kripke D, Remick RA, Sadovnick AD, McElroy SL, Keck PE, Kelsoe JR. Examination of the clock gene Cryptochrome 1 in bipolar disorder: mutational analysis and absence of evidence for linkage or association. Psychiatr Genet. 2005 Mar; 15(1):45-52. PMID: 15722957.
        View in: PubMed
      68. Björkstén KS, Bjerregaard P, Kripke D. Suicides in the midnight sun--a study of seasonality in suicides in West Greenland. Psychiatry Res. 2005 Feb 28; 133(2-3):205-13. PMID: 15740996.
        View in: PubMed
      69. Kripke D, Youngstedt SD, Elliott JA, Tuunainen A, Rex KM, Hauger RL, Marler MR. Circadian phase in adults of contrasting ages. Chronobiol Int. 2005; 22(4):695-709. PMID: 16147900.
        View in: PubMed
      70. Youngstedt SD, Leung A, Kripke D, Langer RD. Association of morning illumination and window covering with mood and sleep among post-menopausal women. Sleep Biol Rhythms. 2004 Oct; 2(3):174-183. PMID: 25374475.
        View in: PubMed
      71. Liu JH, Kripke D, Weinreb RN. Comparison of the nocturnal effects of once-daily timolol and latanoprost on intraocular pressure. Am J Ophthalmol. 2004 Sep; 138(3):389-95. PMID: 15364220.
        View in: PubMed
      72. Yoon IY, Kripke D, Elliott JA, Langer RD. Naps and circadian rhythms in postmenopausal women. J Gerontol A Biol Sci Med Sci. 2004 Aug; 59(8):844-8. PMID: 15345736.
        View in: PubMed
      73. Youngstedt SD, Kripke D. Long sleep and mortality: rationale for sleep restriction. Sleep Med Rev. 2004 Jun; 8(3):159-74. PMID: 15144959.
        View in: PubMed
      74. Kripke D, Jean-Louis G, Elliott JA, Klauber MR, Rex KM, Tuunainen A, Langer RD. Ethnicity, sleep, mood, and illumination in postmenopausal women. BMC Psychiatry. 2004 Apr 07; 4:8. PMID: 15070419; PMCID: PMC400740.
        View in: PubMed, PubMed Central
      75. Grandner MA, Kripke D. Self-reported sleep complaints with long and short sleep: a nationally representative sample. Psychosom Med. 2004 Mar-Apr; 66(2):239-41. PMID: 15039509; PMCID: PMC3687531.
        View in: PubMed, PubMed Central
      76. Kripke D. Do we sleep too much? Sleep. 2004 Feb 01; 27(1):13-4. PMID: 14998231.
        View in: PubMed
      77. Wirz-Justice A, Terman M, Oren DA, Goodwin FK, Kripke D, Whybrow PC, Wisner KL, Wu JC, Lam RW, Berger M, Danilenko KV, Kasper S, Smeraldi E, Takahashi K, Thompson C, van den Hoofdakker RH. Brightening depression. Science. 2004 Jan 23; 303(5657):467-9. PMID: 14739440.
        View in: PubMed
      78. Parry BL, Meliska CJ, Martinez LF, Basavaraj N, Zirpoli GG, Sorenson D, Maurer EL, Lopez A, Markova K, Gamst A, Wolfson T, Hauger R, Kripke D. Menopause: neuroendocrine changes and hormone replacement therapy. J Am Med Womens Assoc (1972). 2004; 59(2):135-45. PMID: 15134429.
        View in: PubMed
      79. Kripke D, Clopton P, Marler MR, Youngstedt SD, Elliott JA. PRC bisection tests. Chronobiol Int. 2003 Nov; 20(6):1117-23. PMID: 14680147.
        View in: PubMed
      80. Liu JH, Bouligny RP, Kripke D, Weinreb RN. Nocturnal elevation of intraocular pressure is detectable in the sitting position. Invest Ophthalmol Vis Sci. 2003 Oct; 44(10):4439-42. PMID: 14507890.
        View in: PubMed
      81. Yoon IY, Kripke D, Elliott JA, Youngstedt SD, Rex KM, Hauger RL. Age-related changes of circadian rhythms and sleep-wake cycles. J Am Geriatr Soc. 2003 Aug; 51(8):1085-91. PMID: 12890070.
        View in: PubMed
      82. Liu JH, Gokhale PA, Loving RT, Kripke D, Weinreb RN. Laboratory assessment of diurnal and nocturnal ocular perfusion pressures in humans. J Ocul Pharmacol Ther. 2003 Aug; 19(4):291-7. PMID: 12964954.
        View in: PubMed
      83. Levine DW, Kaplan RM, Kripke D, Bowen DJ, Naughton MJ, Shumaker SA. Factor structure and measurement invariance of the Women's Health Initiative Insomnia Rating Scale. Psychol Assess. 2003 Jun; 15(2):123-36. PMID: 12847773.
        View in: PubMed
      84. Levine DW, Kripke D, Kaplan RM, Lewis MA, Naughton MJ, Bowen DJ, Shumaker SA. Reliability and validity of the Women's Health Initiative Insomnia Rating Scale. Psychol Assess. 2003 Jun; 15(2):137-48. PMID: 12847774.
        View in: PubMed
      85. Yoon IY, Kripke D, Youngstedt SD, Elliott JA. Actigraphy suggests age-related differences in napping and nocturnal sleep. J Sleep Res. 2003 Jun; 12(2):87-93. PMID: 12753345.
        View in: PubMed
      86. Wang EJ, Kripke D, Stein MT, Parry BL. Measurement of illumination exposure in postpartum women. BMC Psychiatry. 2003 May 13; 3:5. PMID: 12744724; PMCID: PMC156656.
        View in: PubMed, PubMed Central
      87. Kripke D, Youngstedt SD, Rex KM, Klauber MR, Elliott JA. Melatonin excretion with affect disorders over age 60. Psychiatry Res. 2003 May 01; 118(1):47-54. PMID: 12759161.
        View in: PubMed
      88. Yoon IY, Kripke D, Elliott JA, Youngstedt SD. Luteinizing hormone following light exposure in healthy young men. Neurosci Lett. 2003 Apr 24; 341(1):25-8. PMID: 12676335.
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      89. Kripke D. Ineffectiveness of intermittent zolpidem. Sleep Med Rev. 2003 Apr; 7(2):193; author reply 195-6. PMID: 12628218.
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      90. Liu JH, Zhang X, Kripke D, Weinreb RN. Twenty-four-hour intraocular pressure pattern associated with early glaucomatous changes. Invest Ophthalmol Vis Sci. 2003 Apr; 44(4):1586-90. PMID: 12657596.
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      91. Youngstedt SD, Perlis ML, O'Brien PM, Palmer CR, Smith MT, Orff HJ, Kripke D. No association of sleep with total daily physical activity in normal sleepers. Physiol Behav. 2003 Mar; 78(3):395-401. PMID: 12676274.
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      92. Palmer CR, Kripke D, Savage HC, Cindrich LA, Loving RT, Elliott JA. Efficacy of enhanced evening light for advanced sleep phase syndrome. Behav Sleep Med. 2003; 1(4):213-26. PMID: 15602801.
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      93. Smith JS, Kripke D, Elliott JA, Youngstedt SD. Illumination of upper and middle visual fields produces equivalent suppression of melatonin in older volunteers. Chronobiol Int. 2002 Sep; 19(5):883-91. PMID: 12405551.
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      94. Liu JH, Kripke D, Twa MD, Gokhale PA, Jones EI, Park EH, Meehan JE, Weinreb RN. Twenty-four-hour pattern of intraocular pressure in young adults with moderate to severe myopia. Invest Ophthalmol Vis Sci. 2002 Jul; 43(7):2351-5. PMID: 12091437.
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      95. Youngstedt SD, Kripke D, Elliott JA, Assmus JD. No association of 6-sulfatoxymelatonin with in-bed 60-Hz magnetic field exposure or illumination level among older adults. Environ Res. 2002 Jul; 89(3):201-9. PMID: 12176004.
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      96. Tuunainen A, Kripke D, Elliott JA, Assmus JD, Rex KM, Klauber MR, Langer RD. Depression and endogenous melatonin in postmenopausal women. J Affect Disord. 2002 May; 69(1-3):149-58. PMID: 12103461.
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      97. Gehrman P, Stepnowsky C, Cohen-Zion M, Marler M, Kripke D, Ancoli-Israel S. Long-term follow-up of periodic limb movements in sleep in older adults. Sleep. 2002 May 01; 25(3):340-3. PMID: 12003165.
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      98. Wallace-Guy GM, Kripke D, Jean-Louis G, Langer RD, Elliott JA, Tuunainen A. Evening light exposure: implications for sleep and depression. J Am Geriatr Soc. 2002 Apr; 50(4):738-9. PMID: 11982677.
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      99. Kripke D, Garfinkel L, Wingard DL, Klauber MR, Marler MR. Mortality associated with sleep duration and insomnia. Arch Gen Psychiatry. 2002 Feb; 59(2):131-6. PMID: 11825133.
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      100. Cole RJ, Smith JS, Alcalá YC, Elliott JA, Kripke D. Bright-light mask treatment of delayed sleep phase syndrome. J Biol Rhythms. 2002 Feb; 17(1):89-101. PMID: 11837952.
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      101. Ancoli-Israel S, Martin JL, Kripke D, Marler M, Klauber MR. Effect of light treatment on sleep and circadian rhythms in demented nursing home patients. J Am Geriatr Soc. 2002 Feb; 50(2):282-9. PMID: 12028210; PMCID: PMC2764401.
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      102. Loving RT, Kripke D, Shuchter SR. Bright light augments antidepressant effects of medication and wake therapy. Depress Anxiety. 2002; 16(1):1-3. PMID: 12203667.
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      103. Youngstedt SD, Kripke D, Elliott JA. Circadian phase-delaying effects of bright light alone and combined with exercise in humans. Am J Physiol Regul Integr Comp Physiol. 2002 Jan; 282(1):R259-66. PMID: 11742846.
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      104. Ando K, Kripke D, Ancoli-Israel S. Delayed and advanced sleep phase symptoms. Isr J Psychiatry Relat Sci. 2002; 39(1):11-8. PMID: 12013705.
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      105. Kripke D, Brunner R, Freeman R, Hendrix SL, Jackson RD, Masaki K, Carter RA. Sleep Complaints of Postmenopausal Women. Clin J Womens Health. 2001 Dec 01; 1(5):244-252. PMID: 21461131.
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      106. Kripke D. Chronic hypnotic use: deadly risks, doubtful benefit. REVIEW ARTICLE. Sleep Med Rev. 2000 Feb; 4(1):5-20. PMID: 12531158.
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      107. Kripke D. Light treatment for nonseasonal depression: speed, efficacy, and combined treatment. J Affect Disord. 1998 May; 49(2):109-17. PMID: 9609674.
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      108. Kripke D, Elliot JA, Youngstedt SD, Smith JS. Melatonin: marvel or marker? Ann Med. 1998 Feb; 30(1):81-7. PMID: 9556093.
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