Christopher Lee

Title(s)	Assistant Professor, Molecular Biology
School	Vc-academic Affairs
Address	9500 Gilman Drive # La Jolla CA 92093
ORCID	0000-0002-0670-2308
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Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Author Correction: Spatial modeling algorithms for reactions and transport in biological cells. Nat Comput Sci. 2025 Feb 03. Francis EA, Laughlin JG, Dokken JS, Finsberg HNT, Lee CT, Rognes ME, Rangamani P. PMID: 39901055.

View in: PubMed Mentions: Fields:
Com Computational Biology Sci Science
Coupling between membrane undulations and lipid curvature leads to transient local enrichment of cardiolipin in mitochondrial membranes. bioRxiv. 2025 Jan 22. Lee CT, Venkatraman K, Budin I, Rangamani P. PMID: 39896542; PMCID: PMC11785088.

View in: PubMed Mentions:
Spatial modeling algorithms for reactions and transport in biological cells. Nat Comput Sci. 2025 Jan; 5(1):76-89. Francis EA, Laughlin JG, Dokken JS, Finsberg HNT, Lee CT, Rognes ME, Rangamani P. PMID: 39702839; PMCID: PMC11774757.

View in: PubMed Mentions: Fields:
Com Computational Biology Sci Science
Membrane mechanics dictate axonal pearls-on-a-string morphology and function. Nat Neurosci. 2025 Jan; 28(1):49-61. Griswold JM, Bonilla-Quintana M, Pepper R, Lee CT, Raychaudhuri S, Ma S, Gan Q, Syed S, Zhu C, Bell M, Suga M, Yamaguchi Y, Chéreau R, Nägerl UV, Knott G, Rangamani P, Watanabe S. PMID: 39623218; PMCID: PMC11706780.

View in: PubMed Mentions: 1 Fields:
Neu Neurology
Translation:Animals Cells
Setting the curve: the biophysical properties of lipids in mitochondrial form and function. J Lipid Res. 2024 Oct; 65(10):100643. Venkatraman K, Lee CT, Budin I. PMID: 39303982; PMCID: PMC11513603.

View in: PubMed Mentions: Fields:
Bio Biochemistry
Translation:Humans Animals Cells
Biophysical Modeling of Synaptic Plasticity. Annu Rev Biophys. 2024 Jul; 53(1):397-426. Lee CT, Bell M, Bonilla-Quintana M, Rangamani P. PMID: 38382115.

View in: PubMed Mentions: Fields:
Bio Biophysics
Translation:Humans Animals Cells
Modeling the mechanochemical feedback for membrane-protein interactions using a continuum mesh model. Methods Enzymol. 2024; 701:387-424. Lee CT, Rangamani P. PMID: 39025577.

View in: PubMed Mentions: Fields:
Bio Biochemistry
Translation:Cells
Cristae formation is a mechanical buckling event controlled by the inner mitochondrial membrane lipidome. EMBO J. 2023 Dec 11; 42(24):e114054. Venkatraman K, Lee CT, Garcia GC, Mahapatra A, Milshteyn D, Perkins G, Kim KY, Pasolli HA, Phan S, Lippincott-Schwartz J, Ellisman MH, Rangamani P, Budin I. PMID: 37933600; PMCID: PMC10711667.

View in: PubMed Mentions: 7 Fields:
Bio Biotechnology Mol Molecular Biology
ActuAtor, a Listeria-inspired molecular tool for physical manipulation of intracellular organizations through de novo actin polymerization. Cell Rep. 2023 10 31; 42(10):113089. Nakamura H, Rho E, Lee CT, Itoh K, Deng D, Watanabe S, Razavi S, Matsubayashi HT, Zhu C, Jung E, Rangamani P, Watanabe S, Inoue T. PMID: 37734382; PMCID: PMC10872831.

View in: PubMed Mentions: 2 Fields:
Cel Cell Biology Mol Molecular Biology
Translation:Cells
Cristae formation is a mechanical buckling event controlled by the inner membrane lipidome. bioRxiv. 2023 Sep 02. Venkatraman K, Lee CT, Garcia GC, Mahapatra A, Milshteyn D, Perkins G, Kim KY, Pasolli HA, Phan S, Lippincott-Schwartz J, Ellisman MH, Rangamani P, Budin I. PMID: 36993370; PMCID: PMC10054968.

View in: PubMed Mentions:
Membrane mechanics dictate axonal morphology and function. bioRxiv. 2023 Jul 21. Griswold JM, Bonilla-Quintana M, Pepper R, Lee CT, Raychaudhuri S, Ma S, Gan Q, Syed S, Zhu C, Bell M, Suga M, Yamaguchi Y, Chéreau R, Nägerl UV, Knott G, Rangamani P, Watanabe S. PMID: 37503105; PMCID: PMC10370128.

View in: PubMed Mentions:
The ins and outs of membrane bending by intrinsically disordered proteins. Sci Adv. 2023 07 07; 9(27):eadg3485. Yuan F, Lee CT, Sangani A, Houser JR, Wang L, Lafer EM, Rangamani P, Stachowiak JC. PMID: 37418523; PMCID: PMC10328403.

View in: PubMed Mentions: 8 Fields:
Sci Science
Spatiotemporal modelling reveals geometric dependence of AMPAR dynamics on dendritic spine morphology. J Physiol. 2023 08; 601(15):3329-3350. Bell MK, Lee CT, Rangamani P. PMID: 36326020.

View in: PubMed Mentions: 3 Fields:
Phy Physiology
Translation:Cells
Role of the Triplet State and Protein Dynamics in the Formation and Stability of the Tryptophan Radical in an Apoazurin Mutant. J Phys Chem B. 2022 09 15; 126(36):6751-6761. López-Peña I, Lee CT, Rivera JJ, Kim JE. PMID: 35977067; PMCID: PMC9483921.

View in: PubMed Mentions: 3 Fields:
Che Chemistry
Dendritic spine morphology regulates calcium-dependent synaptic weight change. J Gen Physiol. 2022 08 01; 154(8). Bell MK, Holst MV, Lee CT, Rangamani P. PMID: 35819365; PMCID: PMC9280073.

View in: PubMed Mentions: 5 Fields:
Phy Physiology
Translation:Cells
Mem3DG: Modeling membrane mechanochemical dynamics in 3D using discrete differential geometry. Biophys Rep (N Y). 2022 Sep 14; 2(3). Zhu C, Lee CT, Rangamani P. PMID: 36157269; PMCID: PMC9495267.

View in: PubMed Mentions: 8
Benchmarking ensemble docking methods in D3R Grand Challenge 4. J Comput Aided Mol Des. 2022 02; 36(2):87-99. Gan JL, Kumar D, Chen C, Taylor BC, Jagger BR, Amaro RE, Lee CT. PMID: 35199221; PMCID: PMC8907095.

View in: PubMed Mentions: 1 Fields:
Bio Biomedical Engineering Mol Molecular Biology
Translation:Humans Cells
Morphological principles of neuronal mitochondria. J Comp Neurol. 2022 04; 530(6):886-902. Mendelsohn R, Garcia GC, Bartol TM, Lee CT, Khandelwal P, Liu E, Spencer DJ, Husar A, Bushong EA, Phan S, Perkins G, Ellisman MH, Skupin A, Sejnowski TJ, Rangamani P. PMID: 34608995; PMCID: PMC8831469.

View in: PubMed Mentions: 9 Fields:
Neu Neurology
Translation:Animals Cells
Independent Markov decomposition: Toward modeling kinetics of biomolecular complexes. Proc Natl Acad Sci U S A. 2021 08 03; 118(31). Hempel T, Del Razo MJ, Lee CT, Taylor BC, Amaro RE, Noé F. PMID: 34321356; PMCID: PMC8346863.

View in: PubMed Mentions: 5 Fields:
Sci Science
Translation:Cells
Value of models for membrane budding. Curr Opin Cell Biol. 2021 08; 71:38-45. Lee CT, Akamatsu M, Rangamani P. PMID: 33706232; PMCID: PMC8328869.

View in: PubMed Mentions: 2 Fields:
Cel Cell Biology
Translation:Cells
3D mesh processing using GAMer 2 to enable reaction-diffusion simulations in realistic cellular geometries. PLoS Comput Biol. 2020 04; 16(4):e1007756. Lee CT, Laughlin JG, Angliviel de La Beaumelle N, Amaro RE, McCammon JA, Ramamoorthi R, Holst M, Rangamani P. PMID: 32251448; PMCID: PMC7162555.

View in: PubMed Mentions: 17 Fields:
Com Computational Biology
Translation:Humans Cells
An Open-Source Mesh Generation Platform for Biophysical Modeling Using Realistic Cellular Geometries. Biophys J. 2020 03 10; 118(5):1003-1008. Lee CT, Laughlin JG, Moody JB, Amaro RE, McCammon JA, Holst M, Rangamani P. PMID: 32032503; PMCID: PMC7063475.

View in: PubMed Mentions: 9 Fields:
Bio Biophysics
Applications and Challenges of Machine Learning to Enable Realistic Cellular Simulations. Front Phys. 2020 Jan; 7. Vasan R, Rowan MP, Lee CT, Johnson GR, Rangamani P, Holst M. PMID: 36188416; PMCID: PMC9521042.

View in: PubMed Mentions: 3
The Implementation of the Colored Abstract Simplicial Complex and its Application to Mesh Generation. ACM Trans Math Softw. 2019 Aug; 45(3). Lee CT, Moody JB, Amaro RE, McCammon JA, Holst MJ. PMID: 31474782; PMCID: PMC6716611.

View in: PubMed Mentions: 4
Structural basis for ligand modulation of the CCR2 conformational landscape. Proc Natl Acad Sci U S A. 2019 04 23; 116(17):8131-8136. Taylor BC, Lee CT, Amaro RE. PMID: 30975755; PMCID: PMC6486717.

View in: PubMed Mentions: 15 Fields:
Sci Science
Translation:Humans Cells
Exascale Computing: A New Dawn for Computational Biology. Comput Sci Eng. 2018 Sep-Oct; 20(5):18-25. Lee CT, Amaro RE. PMID: 30983889; PMCID: PMC6458592.

View in: PubMed Mentions: 9
Quantitative Ranking of Ligand Binding Kinetics with a Multiscale Milestoning Simulation Approach. J Phys Chem Lett. 2018 Sep 06; 9(17):4941-4948. Jagger BR, Lee CT, Amaro RE. PMID: 30070844; PMCID: PMC6443090.

View in: PubMed Mentions: 16 Fields:
Che Chemistry
Two Relations to Estimate Membrane Permeability Using Milestoning. J Phys Chem B. 2016 08 25; 120(33):8606-16. Votapka LW, Lee CT, Amaro RE. PMID: 27154639; PMCID: PMC5002937.

View in: PubMed Mentions: 24 Fields:
Che Chemistry
Translation:Cells
Simulation-Based Approaches for Determining Membrane Permeability of Small Compounds. J Chem Inf Model. 2016 04 25; 56(4):721-33. Lee CT, Comer J, Herndon C, Leung N, Pavlova A, Swift RV, Tung C, Rowley CN, Amaro RE, Chipot C, Wang Y, Gumbart JC. PMID: 27043429; PMCID: PMC5280572.

View in: PubMed Mentions: 72 Fields:
Che Chemistry Med Medical Informatics
Translation:Cells
Emerging Computational Methods for the Rational Discovery of Allosteric Drugs. Chem Rev. 2016 06 08; 116(11):6370-90. Wagner JR, Lee CT, Durrant JD, Malmstrom RD, Feher VA, Amaro RE. PMID: 27074285; PMCID: PMC4901368.

View in: PubMed Mentions: 81 Fields:
Che Chemistry
Translation:Cells
On the Application of Molecular-Dynamics Based Markov State Models to Functional Proteins. J Chem Theory Comput. 2014 Jul 08; 10(7):2648-2657. Malmstrom RD, Lee CT, Van Wart A, Amaro RE. PMID: 25473382; PMCID: PMC4248791.

View in: PubMed Mentions: 41 Fields:
Bio Biochemistry Che Chemistry