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Christopher Stout

Title(s)Professor, Political Science
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Structural and thermodynamic basis of (+)-α-pinene binding to human cytochrome P450 2B6. J Am Chem Soc. 2013 Jul 17; 135(28):10433-40. Wilderman PR, Shah MB, Jang HH, Stout CD, Halpert JR. PMID: 23786449; PMCID: PMC3754432.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    2. A structural snapshot of CYP2B4 in complex with paroxetine provides insights into ligand binding and clusters of conformational states. J Pharmacol Exp Ther. 2013 Jul; 346(1):113-20. Shah MB, Kufareva I, Pascual J, Zhang Q, Stout CD, Halpert JR. PMID: 23633618; PMCID: PMC3684837.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    3. Conformational adaptation of human cytochrome P450 2B6 and rabbit cytochrome P450 2B4 revealed upon binding multiple amlodipine molecules. Biochemistry. 2012 Sep 18; 51(37):7225-38. Shah MB, Wilderman PR, Pascual J, Zhang Q, Stout CD, Halpert JR. PMID: 22909231; PMCID: PMC3485383.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    4. Investigation by site-directed mutagenesis of the role of cytochrome P450 2B4 non-active-site residues in protein-ligand interactions based on crystal structures of the ligand-bound enzyme. FEBS J. 2012 May; 279(9):1607-20. Wilderman PR, Gay SC, Jang HH, Zhang Q, Stout CD, Halpert JR. PMID: 22051155; PMCID: PMC3911823.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    5. Structures of cytochrome P450 2B6 bound to 4-benzylpyridine and 4-(4-nitrobenzyl)pyridine: insight into inhibitor binding and rearrangement of active site side chains. Mol Pharmacol. 2011 Dec; 80(6):1047-55. Shah MB, Pascual J, Zhang Q, Stout CD, Halpert JR. PMID: 21875942; PMCID: PMC3228530.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    6. Structural analysis of mammalian cytochrome P450 2B4 covalently bound to the mechanism-based inactivator tert-butylphenylacetylene: insight into partial enzymatic activity. Biochemistry. 2011 Jun 07; 50(22):4903-11. Gay SC, Zhang H, Wilderman PR, Roberts AG, Liu T, Li S, Lin HL, Zhang Q, Woods VL, Stout CD, Hollenberg PF, Halpert JR. PMID: 21510666; PMCID: PMC3105221.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    7. Plasticity of cytochrome P450 2B4 as investigated by hydrogen-deuterium exchange mass spectrometry and X-ray crystallography. J Biol Chem. 2010 Dec 03; 285(49):38602-11. Wilderman PR, Shah MB, Liu T, Li S, Hsu S, Roberts AG, Goodlett DR, Zhang Q, Woods VL, Stout CD, Halpert JR. PMID: 20880847; PMCID: PMC2992292.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    8. Structures of cytochrome P450 2B4 complexed with the antiplatelet drugs ticlopidine and clopidogrel . Biochemistry. 2010 Oct 12; 49(40):8709-20. Gay SC, Roberts AG, Maekawa K, Talakad JC, Hong WX, Zhang Q, Stout CD, Halpert JR. PMID: 20815363; PMCID: PMC3005796.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    9. Crystal structure of a cytochrome P450 2B6 genetic variant in complex with the inhibitor 4-(4-chlorophenyl)imidazole at 2.0-A resolution. Mol Pharmacol. 2010 Apr; 77(4):529-38. Gay SC, Shah MB, Talakad JC, Maekawa K, Roberts AG, Wilderman PR, Sun L, Yang JY, Huelga SC, Hong WX, Zhang Q, Stout CD, Halpert JR. PMID: 20061448; PMCID: PMC2845937.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    10. Crystal structures of cytochrome P450 2B4 in complex with the inhibitor 1-biphenyl-4-methyl-1H-imidazole: ligand-induced structural response through alpha-helical repositioning. Biochemistry. 2009 Jun 09; 48(22):4762-71. Gay SC, Sun L, Maekawa K, Halpert JR, Stout CD. PMID: 19397311; PMCID: PMC2764533.
      View in: PubMed   Mentions: 33     Fields:    Translation:Cells
    11. Expression, purification, crystallization and preliminary X-ray analysis of the olfactomedin domain from the sea urchin cell-adhesion protein amassin. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Jan 01; 62(Pt 1):16-9. Hillier BJ, Sundaresan V, Stout CD, Vacquier VD. PMID: 16511251; PMCID: PMC2150939.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    12. Cytochrome rC552, formed during expression of the truncated, Thermus thermophilus cytochrome c552 gene in the cytoplasm of Escherichia coli, reacts spontaneously to form protein-bound 2-formyl-4-vinyl (Spirographis) heme. Biochemistry. 2004 Sep 28; 43(38):12162-76. Fee JA, Todaro TR, Luna E, Sanders D, Hunsicker-Wang LM, Patel KM, Bren KL, Gomez-Moran E, Hill MG, Ai J, Loehr TM, Oertling WA, Williams PA, Stout CD, McRee D, Pastuszyn A. PMID: 15379555.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    13. High-resolution structure of the soluble, respiratory-type Rieske protein from Thermus thermophilus: analysis and comparison. Biochemistry. 2003 Jun 24; 42(24):7303-17. Hunsicker-Wang LM, Heine A, Chen Y, Luna EP, Todaro T, Zhang YM, Williams PA, McRee DE, Hirst J, Stout CD, Fee JA. PMID: 12809486.
      View in: PubMed   Mentions: 36     Fields:    Translation:Cells
    14. Species-specific sequences of abalone lysin, the sperm protein that creates a hole in the egg envelope. Proc Natl Acad Sci U S A. 1990 Aug; 87(15):5792-6. Vacquier VD, Carner KR, Stout CD. PMID: 2377618; PMCID: PMC54414.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
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