Christopher Schafer

Title(s)Postdoctoral Scholar, School of Pharmacy and Pharmaceutical Science
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Biased agonsim of CXCL12 stimulation of the atypical and classical receptors, ACKR3 and CXCR4
    NIH F32GM137505Mar 16, 2020 - Mar 15, 2023
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Novel fluorescent GPCR biosensor detects retinal equilibrium binding to opsin and active G protein and arrestin signaling conformations. J Biol Chem. 2020 12 18; 295(51):17486-17496. Schafer CT, Shumate A, Farrens DL. PMID: 33453993; PMCID: PMC7762930.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    2. Crystal structure of a natural light-gated anion channelrhodopsin. Elife. 2019 01 07; 8. Li H, Huang CY, Govorunova EG, Schafer CT, Sineshchekov OA, Wang M, Zheng L, Spudich JL. PMID: 30614787; PMCID: PMC6336409.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    3. Decay of an active GPCR: Conformational dynamics govern agonist rebinding and persistence of an active, yet empty, receptor state. Proc Natl Acad Sci U S A. 2016 10 18; 113(42):11961-11966. Schafer CT, Fay JF, Janz JM, Farrens DL. PMID: 27702898; PMCID: PMC5081659.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    4. Conformational selection and equilibrium governs the ability of retinals to bind opsin. J Biol Chem. 2015 Feb 13; 290(7):4304-18. Schafer CT, Farrens DL. PMID: 25451936; PMCID: PMC4326838.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    5. Rhodopsin TM6 can interact with two separate and distinct sites on arrestin: evidence for structural plasticity and multiple docking modes in arrestin-rhodopsin binding. Biochemistry. 2014 May 27; 53(20):3294-307. Sinha A, Jones Brunette AM, Fay JF, Schafer CT, Farrens DL. PMID: 24724832; PMCID: PMC4039336.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
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