Chirag Dhar

TitlePostdoctoral Scholar
InstitutionUniversity of California San Diego
DepartmentCellular and Molecular Medicine
Address9500 Gilman Drive #0687
La Jolla CA 92093
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    Collapse Biography 
    Collapse Education and Training
    Rajiv Gandhi University of Health Sciences, Bangalore, IndiaM.B.,B.S. (US M.D. equivalent)04/2016Medicine and Surgery
    University of California, San Diego, La JollaFellowshipOngoingCellular and Molecular Medicine, Glycobiology
    Collapse Awards and Honors
    National Lung Cancer Conference, Bhubaneswar, India 2017Award oral paper presentation
    Indian Institute of Science, Bangalore, India2016Certificate for innovative device design at MeDHa-2016 (Medical Device Hackathon)
    Bill and Melinda Gates Foundation/DBT, India2016Finalist at the Grand Challenges India, 2016

    Collapse Overview 
    Collapse Overview
    Presently, I am training as a postdoctoral fellow in Dr. Ajit Varki’s laboratory at the UC San Diego School of Medicine. My training and research are at the unique tri-junction of glycobiology, immunology and medicine. The Varki Lab, over the past two decades, has discovered the pathogenic role of a non-human sialic acid that gets incorporated in humans who consume processed red meat. This non-human sialic acid promotes a state of sub-clinical inflammation which may be aggravating cancers of epithelial origin. Importantly, many of these cancers express this sialic acid on their cell surfaces. I am presently working on a collaborative effort to develop a monoclonal antibody against this non-human sialic acid that likely has diagnostic and therapeutic implications in multiple epithelial cancers.

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Alampalli SV, Thomson MM, Sampathkumar R, Sivaraman K, U K J AJ, Dhar C, D Souza G, Berry N, Vyakarnam A. Deep sequencing of near full-length HIV-1 genomes from plasma identifies circulating subtype C and infrequent occurrence of AC recombinant form in Southern India. PLoS One. 2017; 12(12):e0188603. PMID: 29220350.
      View in: PubMed
    2. Rakshit S, Adiga V, Nayak S, Sahoo PN, Sharma PK, van Meijgaarden KE, Uk J AJ, Dhar C, Souza GD, Finak G, De Rosa SC, Ottenhoff THM, Vyakarnam A. Circulating Mycobacterium tuberculosis DosR latency antigen-specific, polyfunctional, regulatory IL10+ Th17 CD4 T-cells differentiate latent from active tuberculosis. Sci Rep. 2017 Sep 20; 7(1):11948. PMID: 28931830.
      View in: PubMed
    3. Dhar C, Sharma M, Nawaz M S, D’Souza G, Srivastava S.National Lung Cancer Conference, Bhubaneswar, India. Sanger sequencing of metastatic pleural effusion: An inexpensive, minimally invasive tool for the detection of EGFR mutations in lung adenocarcinoma. 2017.
    4. Sambarey A, Devaprasad A, Mohan A, Ahmed A, Nayak S, Swaminathan S, D'Souza G, Jesuraj A, Dhar C, Babu S, Vyakarnam A, Chandra N. Unbiased Identification of Blood-based Biomarkers for Pulmonary Tuberculosis by Modeling and Mining Molecular Interaction Networks. EBioMedicine. 2017 Feb; 15:112-126. PMID: 28065665.
      View in: PubMed
    5. Suraj S, Dhar C, Srivastava S. Circulating nucleic acids: An analysis of their occurrence in malignancies. Biomed Rep. 2017 Jan; 6(1):8-14. PMID: 28123700.
      View in: PubMed