Loading...

Charles Perrin

Title(s)Emeritus Professor, Chemistry and Biochemistry
SchoolAcademic Aff
Phone858-534-2164
vCardDownload vCard

    Collapse Research 
    Collapse Research Activities and Funding
    SYMMETRY OF HYDROGEN BONDS
    NIH/NIGMS R01GM044527Aug 1, 1995 - Jul 31, 2000
    Role: Principal Investigator
    MECHANISMS OF REACTIONS OF OXYGEN WITH HEME PROTEINS
    NIH/NHLBI R01HL013581Feb 1, 1979 - Jun 30, 1999
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Perrin CL, Wu Y. Symmetry of Hydrogen Bonds in Two Enols in Solution. J Am Chem Soc. 2019 Feb 08. PMID: 30734554.
      View in: PubMed
    2. Perrin CL. Polynomial coefficients. Application to spin-spin splitting by N equivalent nuclei of spin I > 1/2. Magn Reson Chem. 2018 Sep; 56(9):799-802. PMID: 29676807.
      View in: PubMed
    3. Devaraj NK, Perrin CL. Approach control. Stereoelectronic origin of geometric constraints on N-to-S and N-to-O acyl shifts in peptides. Chem Sci. 2018 Feb 21; 9(7):1789-1794. PMID: 29675223.
      View in: PubMed
    4. Perrin CL. pH-Free Measurement of Relative Acidities, Including Isotope Effects. Methods Enzymol. 2017; 596:331-368. PMID: 28911776.
      View in: PubMed
    5. Perrin CL. The Logic behind a Physical-Organic Chemist's Research Topics. J Org Chem. 2017 01 20; 82(2):819-838. PMID: 28103693.
      View in: PubMed
    6. Perrin CL, Chang KL. The Complete Mechanism of an Aldol Condensation. J Org Chem. 2016 07 01; 81(13):5631-5. PMID: 27281298.
      View in: PubMed
    7. Hart-Cooper WM, Sgarlata C, Perrin CL, Toste FD, Bergman RG, Raymond KN. Protein-like proton exchange in a synthetic host cavity. Proc Natl Acad Sci U S A. 2015 Dec 15; 112(50):15303-7. PMID: 26621709.
      View in: PubMed
    8. Perrin CL, Burke KD. Can a secondary isotope effect be larger than a primary? J Phys Chem A. 2015 May 21; 119(20):5009-18. PMID: 25879248.
      View in: PubMed
    9. Carpenter AE, McNeece AJ, Barnett BR, Estrada AL, Mokhtarzadeh CC, Moore CE, Rheingold AL, Perrin CL, Figueroa JS. Direct observation of ß-chloride elimination from an isolable ß-chloroalkyl complex of square-planar nickel. J Am Chem Soc. 2014 Nov 05; 136(44):15481-4. PMID: 25317481.
      View in: PubMed
    10. Perrin CL, Reyes-Rodríguez GJ. Selectivity and isotope effects in hydronation of a naked aryl anion. J Am Chem Soc. 2014 Oct 29; 136(43):15263-9. PMID: 25279775.
      View in: PubMed
    11. Perrin CL, Burke KD. Variable-temperature study of hydrogen-bond symmetry in cyclohexene-1,2-dicarboxylate monoanion in chloroform-d. J Am Chem Soc. 2014 Mar 19; 136(11):4355-62. PMID: 24527684.
      View in: PubMed
    12. Perrin CL, Flach A, Manalo MN. Decomposition of malonic anhydrides. J Am Chem Soc. 2012 Jun 13; 134(23):9698-707. PMID: 22625847.
      View in: PubMed
    13. Perrin CL, Karri P, Moore C, Rheingold AL. Hydrogen-bond symmetry in difluoromaleate monoanion. J Am Chem Soc. 2012 May 09; 134(18):7766-72. PMID: 22519701.
      View in: PubMed
    14. Dopieralski P, Perrin CL, Latajka Z. On the Intramolecular Hydrogen Bond in Solution: Car-Parrinello and Path Integral Molecular Dynamics Perspective. J Chem Theory Comput. 2011 Nov 08; 7(11):3505-13. PMID: 26598249.
      View in: PubMed
    15. Perrin CL, Flach A. No contribution of an inductive effect to secondary deuterium isotope effects on acidity. Angew Chem Int Ed Engl. 2011 Aug 08; 50(33):7674-6. PMID: 21710519.
      View in: PubMed
    16. Perrin CL. Are short, low-barrier hydrogen bonds unusually strong? Acc Chem Res. 2010 Dec 21; 43(12):1550-7. PMID: 20939528.
      View in: PubMed
    17. Perrin CL, Karri P. Position-specific secondary deuterium isotope effects on basicity of pyridine. J Am Chem Soc. 2010 Sep 01; 132(34):12145-9. PMID: 20701292.
      View in: PubMed
    18. Perrin CL, Karri P. Are there single-well hydrogen bonds in pyridine-dichloroacetic acid complexes? Chem Commun (Camb). 2010 Jan 21; 46(3):481-3. PMID: 20066332.
      View in: PubMed
    19. Perrin CL, Lau JS, Kim YJ, Karri P, Moore C, Rheingold AL. Asymmetry of the "strongest" OHO hydrogen bond, in the monoanion of (+/-)-alpha,alpha'-di-tert-butylsuccinate. J Am Chem Soc. 2009 Sep 23; 131(37):13548-54. PMID: 19691344.
      View in: PubMed
    20. Perrin CL, Dong Y. Nonadditivity of secondary deuterium isotope effects on basicity of trimethylamine. J Am Chem Soc. 2008 Aug 20; 130(33):11143-8. PMID: 18661997.
      View in: PubMed
    21. Perrin CL, Zhao C. Intramolecular kinetic isotope effect in hydride transfer from dihydroacridine to a quinolinium ion. Rejection of a proposed two-step mechanism with a kinetically significant intermediate. Org Biomol Chem. 2008 Sep 21; 6(18):3349-53. PMID: 18802641.
      View in: PubMed
    22. Perrin CL, Rodgers BL, O'Connor JM. Nucleophilic addition to a p-benzyne derived from an enediyne: a new mechanism for halide incorporation into biomolecules. J Am Chem Soc. 2007 Apr 18; 129(15):4795-9. PMID: 17378569.
      View in: PubMed
    23. Perrin CL, Dong Y. Secondary deuterium isotope effects on the acidity of carboxylic acids and phenols. J Am Chem Soc. 2007 Apr 11; 129(14):4490-7. PMID: 17358063.
      View in: PubMed
    24. Perrin CL, Lau JS. Hydrogen-bond symmetry in zwitterionic phthalate anions: symmetry breaking by solvation. J Am Chem Soc. 2006 Sep 13; 128(36):11820-4. PMID: 16953621.
      View in: PubMed
    25. Perrin CL, Ohta BK, Kuperman J, Liberman J, Erdélyi M. Stereochemistry of beta-deuterium isotope effects on amine basicity. J Am Chem Soc. 2005 Jul 06; 127(26):9641-7. PMID: 15984892.
      View in: PubMed
    26. Perrin CL, Erdélyi M. One-bond C-C coupling constants in ethers are not primarily determined by N-sigma delocalization. J Am Chem Soc. 2005 May 04; 127(17):6168-9. PMID: 15853311.
      View in: PubMed
    27. Cuevas G, Martínez-Mayorga K, del Carmen Fernández-Alonso M, Jiménez-Barbero J, Perrin CL, Juaristi E, López-Mora N. The origin of one-bond C-H coupling constants in OCH fragments: not primarily nO-->sigma CH delocalization. Angew Chem Int Ed Engl. 2005 Apr 15; 44(16):2360-4. PMID: 15761904.
      View in: PubMed
    28. Perrin CL, Ohta BK, Kuperman J. Beta-deuterium isotope effects on amine basicity, "inductive" and stereochemical. J Am Chem Soc. 2003 Dec 10; 125(49):15008-9. PMID: 14653734.
      View in: PubMed
    29. Perrin CL, Kuperman J. Anomeric effects versus steric hindrance to ionic solvation in protonated glucosylanilines and cyclohexylanilines. J Am Chem Soc. 2003 Jul 23; 125(29):8846-51. PMID: 12862481.
      View in: PubMed
    30. Perrin CL, Ohta BK. Symmetry of O-H-O and N-H-N hydrogen bonds in 6-hydroxy-2-formylfulvene and 6-aminofulvene-2-aldimines. Bioorg Chem. 2002 Feb; 30(1):3-15. PMID: 11954999.
      View in: PubMed
    31. Perrin CL. Is there stereoelectronic control in formation and cleavage of tetrahedral intermediates? Acc Chem Res. 2002 Jan; 35(1):28-34. PMID: 11790086.
      View in: PubMed
    32. Perrin CL, Engler RE. Origin of Apparent Stereoelectronic Effects in Structure and Reactivity of Benzoquinone Monooximes. J Org Chem. 1997 Feb 07; 62(3):687-692. PMID: 11671465.
      View in: PubMed
    33. Perrin CL, Nielson JB. "Strong" hydrogen bonds in chemistry and biology. Annu Rev Phys Chem. 1997; 48:511-44. PMID: 9348662.
      View in: PubMed