Loading...
Sign in to edit your profile (add interests, mentoring, photo, etc.)

    Charles Perrin

    TitleProfessor
    SchoolUniversity of California, San Diego
    DepartmentChemistry and Biochemistry
    Address9500 Gilman Drive #0358
    CA La Jolla 92093
    Phone858-534-2164
    vCardDownload vCard

      Collapse Research 
      Collapse Research Activities and Funding
      SYMMETRY OF HYDROGEN BONDS
      NIH/NIGMS R01GM044527Aug 1, 1995 - Jul 31, 2000
      Role: Principal Investigator
      MECHANISMS OF REACTIONS OF OXYGEN WITH HEME PROTEINS
      NIH/NHLBI R01HL013581Feb 1, 1979 - Jun 30, 1999
      Role: Principal Investigator

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Perrin C. pH-Free Measurement of Relative Acidities, Including Isotope Effects. Methods Enzymol. 2017; 596:331-368. PMID: 28911776.
        View in: PubMed
      2. Perrin C. The Logic behind a Physical-Organic Chemist's Research Topics. J Org Chem. 2017 Jan 20; 82(2):819-838. PMID: 28103693.
        View in: PubMed
      3. Perrin C, Chang KL. The Complete Mechanism of an Aldol Condensation. J Org Chem. 2016 Jul 01; 81(13):5631-5. PMID: 27281298.
        View in: PubMed
      4. Hart-Cooper WM, Sgarlata C, Perrin C, Toste FD, Bergman RG, Raymond KN. Protein-like proton exchange in a synthetic host cavity. Proc Natl Acad Sci U S A. 2015 Dec 15; 112(50):15303-7. PMID: 26621709; PMCID: PMC4687555.
      5. Perrin C, Burke KD. Can a secondary isotope effect be larger than a primary? J Phys Chem A. 2015 May 21; 119(20):5009-18. PMID: 25879248.
        View in: PubMed
      6. Carpenter AE, McNeece AJ, Barnett BR, Estrada AL, Mokhtarzadeh CC, Moore CE, Rheingold AL, Perrin C, Figueroa JS. Direct observation of ß-chloride elimination from an isolable ß-chloroalkyl complex of square-planar nickel. J Am Chem Soc. 2014 Nov 05; 136(44):15481-4. PMID: 25317481.
        View in: PubMed
      7. Perrin C, Reyes-Rodríguez GJ. Selectivity and isotope effects in hydronation of a naked aryl anion. J Am Chem Soc. 2014 Oct 29; 136(43):15263-9. PMID: 25279775.
        View in: PubMed
      8. Perrin C, Burke KD. Variable-temperature study of hydrogen-bond symmetry in cyclohexene-1,2-dicarboxylate monoanion in chloroform-d. J Am Chem Soc. 2014 Mar 19; 136(11):4355-62. PMID: 24527684.
        View in: PubMed
      9. Perrin C, Flach A, Manalo MN. Decomposition of malonic anhydrides. J Am Chem Soc. 2012 Jun 13; 134(23):9698-707. PMID: 22625847.
        View in: PubMed
      10. Perrin C, Karri P, Moore C, Rheingold AL. Hydrogen-bond symmetry in difluoromaleate monoanion. J Am Chem Soc. 2012 May 09; 134(18):7766-72. PMID: 22519701.
        View in: PubMed
      11. Dopieralski P, Perrin C, Latajka Z. On the Intramolecular Hydrogen Bond in Solution: Car-Parrinello and Path Integral Molecular Dynamics Perspective. J Chem Theory Comput. 2011 Nov 08; 7(11):3505-13. PMID: 26598249.
        View in: PubMed
      12. Perrin C, Flach A. No contribution of an inductive effect to secondary deuterium isotope effects on acidity. Angew Chem Int Ed Engl. 2011 Aug 08; 50(33):7674-6. PMID: 21710519.
        View in: PubMed
      13. Perrin C. Are short, low-barrier hydrogen bonds unusually strong? Acc Chem Res. 2010 Dec 21; 43(12):1550-7. PMID: 20939528.
        View in: PubMed
      14. Perrin C, Karri P. Position-specific secondary deuterium isotope effects on basicity of pyridine. J Am Chem Soc. 2010 Sep 01; 132(34):12145-9. PMID: 20701292.
        View in: PubMed
      15. Perrin C, Karri P. Are there single-well hydrogen bonds in pyridine-dichloroacetic acid complexes? Chem Commun (Camb). 2010 Jan 21; 46(3):481-3. PMID: 20066332.
        View in: PubMed
      16. Perrin C, Lau JS, Kim YJ, Karri P, Moore C, Rheingold AL. Asymmetry of the "strongest" OHO hydrogen bond, in the monoanion of (+/-)-alpha,alpha'-di-tert-butylsuccinate. J Am Chem Soc. 2009 Sep 23; 131(37):13548-54. PMID: 19691344.
        View in: PubMed
      17. Perrin C, Dong Y. Nonadditivity of secondary deuterium isotope effects on basicity of trimethylamine. J Am Chem Soc. 2008 Aug 20; 130(33):11143-8. PMID: 18661997.
        View in: PubMed
      18. Perrin C, Zhao C. Intramolecular kinetic isotope effect in hydride transfer from dihydroacridine to a quinolinium ion. Rejection of a proposed two-step mechanism with a kinetically significant intermediate. Org Biomol Chem. 2008 Sep 21; 6(18):3349-53. PMID: 18802641.
        View in: PubMed
      19. Perrin C, Rodgers BL, O'Connor JM. Nucleophilic addition to a p-benzyne derived from an enediyne: a new mechanism for halide incorporation into biomolecules. J Am Chem Soc. 2007 Apr 18; 129(15):4795-9. PMID: 17378569.
        View in: PubMed
      20. Perrin C, Dong Y. Secondary deuterium isotope effects on the acidity of carboxylic acids and phenols. J Am Chem Soc. 2007 Apr 11; 129(14):4490-7. PMID: 17358063.
        View in: PubMed
      21. Perrin C, Lau JS. Hydrogen-bond symmetry in zwitterionic phthalate anions: symmetry breaking by solvation. J Am Chem Soc. 2006 Sep 13; 128(36):11820-4. PMID: 16953621.
        View in: PubMed
      22. Perrin C, Ohta BK, Kuperman J, Liberman J, Erdélyi M. Stereochemistry of beta-deuterium isotope effects on amine basicity. J Am Chem Soc. 2005 Jul 06; 127(26):9641-7. PMID: 15984892.
        View in: PubMed
      23. Perrin C, Erdélyi M. One-bond C-C coupling constants in ethers are not primarily determined by N-sigma delocalization. J Am Chem Soc. 2005 May 04; 127(17):6168-9. PMID: 15853311.
        View in: PubMed
      24. Cuevas G, Martínez-Mayorga K, del Carmen Fernández-Alonso M, Jiménez-Barbero J, Perrin C, Juaristi E, López-Mora N. The origin of one-bond C-H coupling constants in OCH fragments: not primarily nO-->sigma CH delocalization. Angew Chem Int Ed Engl. 2005 Apr 15; 44(16):2360-4. PMID: 15761904.
        View in: PubMed
      25. Perrin C, Ohta BK, Kuperman J. Beta-deuterium isotope effects on amine basicity, "inductive" and stereochemical. J Am Chem Soc. 2003 Dec 10; 125(49):15008-9. PMID: 14653734.
        View in: PubMed
      26. Perrin C, Kuperman J. Anomeric effects versus steric hindrance to ionic solvation in protonated glucosylanilines and cyclohexylanilines. J Am Chem Soc. 2003 Jul 23; 125(29):8846-51. PMID: 12862481.
        View in: PubMed
      27. Perrin C, Ohta BK. Symmetry of O-H-O and N-H-N hydrogen bonds in 6-hydroxy-2-formylfulvene and 6-aminofulvene-2-aldimines. Bioorg Chem. 2002 Feb; 30(1):3-15. PMID: 11954999.
        View in: PubMed
      28. Perrin C. Is there stereoelectronic control in formation and cleavage of tetrahedral intermediates? Acc Chem Res. 2002 Jan; 35(1):28-34. PMID: 11790086.
        View in: PubMed
      29. Perrin C, Ohta BK. Symmetry of N-H-N hydrogen bonds in 1,8-bis(dimethylamino)naphthalene.H+ and 2,7-dimethoxy-1,8-bis(dimethylamino)naphthalene.H+. J Am Chem Soc. 2001 Jul 11; 123(27):6520-6. PMID: 11439038.
        View in: PubMed
      30. Perrin C, Young DB. Is there stereoelectronic control in hydrolysis of cyclic guanidinium ions? J Am Chem Soc. 2001 May 16; 123(19):4446-50. PMID: 11457229.
        View in: PubMed
      31. Perrin C, Young DB. Stereoelectronic control in addition of nucleophiles to an amidinium ion. J Am Chem Soc. 2001 May 16; 123(19):4451-8. PMID: 11457230.
        View in: PubMed
      32. Perrin C, Kim YJ. Symmetry of metal chelates. Inorg Chem. 2000 Aug 21; 39(17):3902-10. PMID: 11196787.
        View in: PubMed
      33. Perrin C, Engler RE. Origin of Apparent Stereoelectronic Effects in Structure and Reactivity of Benzoquinone Monooximes. J Org Chem. 1997 Feb 07; 62(3):687-692. PMID: 11671465.
        View in: PubMed
      34. Perrin C, Nielson JB. "Strong" hydrogen bonds in chemistry and biology. Annu Rev Phys Chem. 1997; 48:511-44. PMID: 9348662.
        View in: PubMed
      35. Perrin C, Fabian MA. Multicomponent NMR titration for simultaneous measurement of relative pKaS. Anal Chem. 1996 Jul 01; 68(13):2127-34. PMID: 9027228.
        View in: PubMed
      36. Perrin C, Nunez O. Absence of stereoelectronic control in hydrolysis of cyclic amidines. J Am Chem Soc. 1986 Sep 01; 108(19):5997-6003. PMID: 22175363.
        View in: PubMed
      Charles's Networks
      Concepts
      Derived automatically from this person's publications.
      _
      Co-Authors
      People in Profiles who have published with this person.
      _
      Similar People
      People who share similar concepts with this person.
      _
      Same Department
      Physical Neighbors
      People whose addresses are nearby this person.
      _