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    Changwei Shao

    Address9500 Gilman Drive #0651
    CA La Jolla 92093
    Phone858-405-9749
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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Zhang XQ, Spadafora C, Pineda LM, Ng MG, Sun JH, Wang W, Wang CY, Gu YC, Shao C. Discovery, Semisynthesis, Antiparasitic and Cytotoxic Evaluation of 14-Membered Resorcylic Acid Lactones and Their Derivatives. Sci Rep. 2017 Sep 18; 7(1):11822. PMID: 28924201.
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      2. Liu L, Zhang Z, Shao C, Wang CY. Analysis of the Sequences, Structures, and Functions of Product-Releasing Enzyme Domains in Fungal Polyketide Synthases. Front Microbiol. 2017; 8:1685. PMID: 28928723.
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      3. Jiang L, Shao C, Wu QJ, Chen G, Zhou J, Yang B, Li H, Gou LT, Zhang Y, Wang Y, Yeo GW, Zhou Y, Fu XD. NEAT1 scaffolds RNA-binding proteins and the Microprocessor to globally enhance pri-miRNA processing. Nat Struct Mol Biol. 2017 Aug 28. PMID: 28846091.
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      4. Xin LT, Liu L, Shao C, Yu RL, Chen FL, Yue SJ, Wang M, Guo ZL, Fan YC, Guan HS, Wang CY. Discovery of DNA Topoisomerase I Inhibitors with Low-Cytotoxicity Based on Virtual Screening from Natural Products. Mar Drugs. 2017 Jul 09; 15(7). PMID: 28698495.
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      5. Shi T, Qi J, Shao C, Zhao DL, Hou XM, Wang CY. Bioactive Diphenyl Ethers and Isocoumarin Derivatives from a Gorgonian-Derived Fungus Phoma sp. (TA07-1). Mar Drugs. 2017 May 25; 15(6). PMID: 28587090.
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      6. Wang CY, Wang KL, Qian PY, Xu Y, Chen M, Zheng JJ, Liu M, Shao C, Wang CY. Antifouling phenyl ethers and other compounds from the invertebrates and their symbiotic fungi collected from the South China Sea. AMB Express. 2016 Dec; 6(1):102. PMID: 27785778.
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      7. Zhu K, Lei PJ, Ju LG, Wang X, Huang K, Yang B, Shao C, Zhu Y, Wei G, Fu XD, Li L, Wu M. SPOP-containing complex regulates SETD2 stability and H3K36me3-coupled alternative splicing. Nucleic Acids Res. 2017 Jan 09; 45(1):92-105. PMID: 27614073.
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      8. Qiu J, Zhou B, Thol F, Zhou Y, Chen L, Shao C, DeBoever C, Hou J, Li H, Chaturvedi A, Ganser A, Bejar R, Zhang DE, Fu XD, Heuser M. Distinct splicing signatures affect converged pathways in myelodysplastic syndrome patients carrying mutations in different splicing regulators. RNA. 2016 Oct; 22(10):1535-49. PMID: 27492256.
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      9. Ma J, Zhang XL, Wang Y, Zheng JY, Wang CY, Shao C. Aspergivones A and B, two new flavones isolated from a gorgonian-derived Aspergillus candidus fungus. Nat Prod Res. 2017 Jan; 31(1):32-36. PMID: 27448033.
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      10. Chen M, Zhang W, Shao C, Chi ZM, Wang CY. DNA Methyltransferase Inhibitor Induced Fungal Biosynthetic Products: Diethylene Glycol Phthalate Ester Oligomers from the Marine-Derived Fungus Cochliobolus lunatus. Mar Biotechnol (NY). 2016 Jun; 18(3):409-17. PMID: 27245469.
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      11. Hou XM, Wang CY, Gu YC, Shao C. Penimethavone A, a flavone from a gorgonian-derived fungus Penicillium chrysogenum. Nat Prod Res. 2016 Oct; 30(20):2274-7. PMID: 26998621.
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      12. Xu WF, Hou XM, Yang KL, Cao F, Yang RY, Wang CY, Shao C. Nigrodiquinone A, a Hydroanthraquinone Dimer Containing a Rare C-9-C-7' Linkage from a Zoanthid-Derived Nigrospora sp. Fungus. Mar Drugs. 2016 Mar 09; 14(3). PMID: 27005638; PMCID: PMC4820305.
      13. Fu XM, Zhang MQ, Shao C, Li GQ, Bai H, Dai GL, Chen QW, Kong W, Fu XJ, Wang CY. Chinese Marine Materia Medica Resources: Status and Potential. Mar Drugs. 2016 Mar 03; 14(3). PMID: 26950133; PMCID: PMC4820300.
      14. Bai H, Kong WW, Shao C, Li Y, Liu YZ, Liu M, Guan FF, Wang CY. Zebrafish Embryo Toxicity Microscale Model for Ichthyotoxicity Evaluation of Marine Natural Products. Mar Biotechnol (NY). 2016 Apr; 18(2):264-70. PMID: 26838966.
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      15. Zhao DL, Shao C, Wang CY, Wang M, Yang LJ, Wang CY. Naphthalenones and Depsidones from a Sponge-Derived Strain of the Fungus Corynespora cassiicola. Molecules. 2016 Jan 28; 21(2):160. PMID: 26828473.
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      16. Wang KL, Zhang G, Sun J, Xu Y, Han Z, Liu LL, Shao C, Liu QA, Wang CY, Qian PY. Cochliomycin A inhibits the larval settlement of Amphibalanus amphitrite by activating the NO/cGMP pathway. Biofouling. 2016; 32(1):35-44. PMID: 26732984.
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      17. Zhao HY, Anbuchezhian R, Sun W, Shao C, Zhang FL, Yin Y, Yu ZS, Li ZY, Wang CY. Cytotoxic Nitrobenzoyloxy-substituted Sesquiterpenes from Spongederived Endozoic Fungus Aspergillus insulicola MD10-2. Curr Pharm Biotechnol. 2016; 17(3):271-4. PMID: 26696019.
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      18. Zheng CJ, Shao C, Chen M, Niu ZG, Zhao DL, Wang CY. Merosesquiterpenoids and ten-membered macrolides from a soft coral-derived Lophiostoma sp. fungus. Chem Biodivers. 2015 Sep; 12(9):1407-14. PMID: 26363884.
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      19. Zhao DL, Shao C, Zhang Q, Wang KL, Guan FF, Shi T, Wang CY. Azaphilone and Diphenyl Ether Derivatives from a Gorgonian-Derived Strain of the Fungus Penicillium pinophilum. J Nat Prod. 2015 Sep 25; 78(9):2310-4. PMID: 26291474.
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      20. Jia YL, Wei MY, Chen HY, Guan FF, Wang CY, Shao C. (+)- and (-)-Pestaloxazine A, a Pair of Antiviral Enantiomeric Alkaloid Dimers with a Symmetric Spiro[oxazinane-piperazinedione] Skeleton from Pestalotiopsis sp. Org Lett. 2015 Sep 04; 17(17):4216-9. PMID: 26291636.
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      21. Shao C, Linington RG, Balunas MJ, Centeno A, Boudreau P, Zhang C, Engene N, Spadafora C, Mutka TS, Kyle DE, Gerwick L, Wang CY, Gerwick WH. Bastimolide A, a Potent Antimalarial Polyhydroxy Macrolide from the Marine Cyanobacterium Okeania hirsuta. J Org Chem. 2015 Aug 21; 80(16):7849-55. PMID: 26222145.
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      22. Wang KL, Xu Y, Lu L, Li Y, Han Z, Zhang J, Shao C, Wang CY, Qian PY. Low-Toxicity Diindol-3-ylmethanes as Potent Antifouling Compounds. Mar Biotechnol (NY). 2015 Oct; 17(5):624-32. PMID: 26239187.
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      23. Cao F, Yang Q, Shao C, Kong CJ, Zheng JJ, Liu YF, Wang CY. Bioactive 7-Oxabicyclic[6.3.0]lactam and 12-Membered Macrolides from a Gorgonian-Derived Cladosporium sp. Fungus. Mar Drugs. 2015 Jul 07; 13(7):4171-8. PMID: 26198234; PMCID: PMC4515610.
      24. Sun XP, Cao F, Shao C, Wang M, Zhang XL, Wang CY. Antibacterial ?(1) -3-ketosteroids from the South China Sea gorgonian coral Subergorgia rubra. Chem Biodivers. 2015 Jul; 12(7):1068-74. PMID: 26172327.
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      25. Chen M, Han L, Shao C, She ZG, Wang CY. Erratum: bioactive diphenyl ether derivatives from a gorgonian-derived fungus Talaromyces sp. Chem Biodivers. 2015 Jul; 12(7):1130. PMID: 26172333.
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      26. Liu L, Zhang Z, Shao C, Wang JL, Bai H, Wang CY. Bioinformatical analysis of the sequences, structures and functions of fungal polyketide synthase product template domains. Sci Rep. 2015 May 21; 5:10463. PMID: 25995122.
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      27. Cao F, Wu ZH, Shao C, Pang S, Liang XY, de Voogd NJ, Wang CY. Cytotoxic scalarane sesterterpenoids from the South China Sea sponge Carteriospongia foliascens. Org Biomol Chem. 2015 Apr 07; 13(13):4016-24. PMID: 25723897.
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      28. Shao C, Xu RF, Wang CY, Qian PY, Wang KL, Wei MY. Potent Antifouling Marine Dihydroquinolin-2(1H)-one-Containing Alkaloids from the Gorgonian Coral-Derived Fungus Scopulariopsis sp. Mar Biotechnol (NY). 2015 Aug; 17(4):408-15. PMID: 25833409.
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      29. Chen M, Han L, Shao C, She ZG, Wang CY. Bioactive diphenyl ether derivatives from a gorgonian-derived fungus Talaromyces sp. Chem Biodivers. 2015 Mar; 12(3):443-50. PMID: 25766917.
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      30. Zhao DL, Shao C, Gan LS, Wang M, Wang CY. Chromone derivatives from a sponge-derived strain of the fungus Corynespora cassiicola. J Nat Prod. 2015 Feb 27; 78(2):286-93. PMID: 25594263.
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      31. Hou XM, Xu RF, Gu YC, Wang CY, Shao C. Biological and chemical diversity of coral-derived microorganisms. Curr Med Chem. 2015; 22(32):3707-62. PMID: 26438250.
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      32. Zhang X, Wang S, Chen S, Chen Y, Liu Y, Shao C, Wang Q, Lu Y, Gong G, Ding S, Sha Z. Transcriptome analysis revealed changes of multiple genes involved in immunity in Cynoglossus semilaevis during Vibrio anguillarum infection. Fish Shellfish Immunol. 2015 Mar; 43(1):209-18. PMID: 25543033.
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      33. Sun XP, Cao F, Shao C, Chen M, Liu HJ, Zheng CJ, Wang CY. Subergorgiaols A-L, 9,10-secosteroids from the South China Sea gorgonian Subergorgia rubra. Steroids. 2015 Feb; 94:7-14. PMID: 25528195.
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      34. Chen M, Shao C, Meng H, She ZG, Wang CY. Anti-respiratory syncytial virus prenylated dihydroquinolone derivatives from the gorgonian-derived fungus Aspergillus sp. XS-20090B15. J Nat Prod. 2014 Dec 26; 77(12):2720-4. PMID: 25420212.
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      35. Qin XY, Yang KL, Li J, Wang CY, Shao C. Phylogenetic diversity and antibacterial activity of culturable fungi derived from the zoanthid Palythoa haddoni in the South China Sea. Mar Biotechnol (NY). 2015 Feb; 17(1):99-109. PMID: 25117478.
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      36. Chen M, Shao C, Fu XM, Kong CJ, She ZG, Wang CY. Lumazine peptides penilumamides B-D and the cyclic pentapeptide asperpeptide A from a gorgonian-derived Aspergillus sp. fungus. J Nat Prod. 2014 Jul 25; 77(7):1601-6. PMID: 25001296.
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      37. Liu M, Shao C, Chen M, Qi J, Wang Y, Fang YC, Wang CY. Bioactive 9,11-secosteroids from Gorgonian Subergorgia suberosa collected from the South China sea. Chem Biodivers. 2014 Jul; 11(7):1109-20. PMID: 25044596.
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      38. Cao F, Shao C, Chen M, Zhang MQ, Xu KX, Meng H, Wang CY. Antiviral C-25 epimers of 26-acetoxy steroids from the South China Sea gorgonian Echinogorgia rebekka. J Nat Prod. 2014 Jun 27; 77(6):1488-93. PMID: 24882250.
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      39. Liu QA, Shao C, Gu YC, Blum M, Gan LS, Wang KL, Chen M, Wang CY. Antifouling and Fungicidal Resorcylic Acid Lactones from the Sea Anemone-Derived Fungus Cochliobolus lunatus. J Agric Food Chem. 2014 Mar 25. PMID: 24635109.
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      40. Zheng JJ, Shao C, Chen M, Gan LS, Fang YC, Wang XH, Wang CY. Ochracenoids A and B, guaiazulene-based analogues from gorgonian Anthogorgia ochracea collected from the South China Sea. Mar Drugs. 2014 Mar 14; 12(3):1569-79. PMID: 24637960; PMCID: PMC3967227.
      41. Zhou YM, Shao C, Huang H, Zhang XL, Wang CY. New briarane-type diterpenoids from gorgonian Ellisella dollfusi from the South China Sea. Nat Prod Res. 2014; 28(1):7-11. PMID: 23972040.
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      42. Zheng CJ, Shao C, Wu LY, Chen M, Wang KL, Zhao DL, Sun XP, Chen GY, Wang CY. Bioactive phenylalanine derivatives and cytochalasins from the soft coral-derived fungus, Aspergillus elegans. Mar Drugs. 2013 Jun 10; 11(6):2054-68. PMID: 23752358; PMCID: PMC3721221.
      43. Li YX, Wu HX, Xu Y, Shao C, Wang CY, Qian PY. Antifouling activity of secondary metabolites isolated from chinese marine organisms. Mar Biotechnol (NY). 2013 Oct; 15(5):552-8. PMID: 23613141.
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      44. Shao C, Xu RF, Wei MY, She ZG, Wang CY. Structure and absolute configuration of fumiquinazoline L, an alkaloid from a gorgonian-derived Scopulariopsis sp. fungus. J Nat Prod. 2013 Apr 26; 76(4):779-82. PMID: 23586849.
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      45. Wei MY, Li D, Shao C, Deng DS, Wang CY. (±)-Pestalachloride D, an antibacterial racemate of chlorinated benzophenone derivative from a soft coral-derived fungus Pestalotiopsis sp. Mar Drugs. 2013 Mar 28; 11(4):1050-60. PMID: 23538869; PMCID: PMC3705387.
      46. Chen M, Shao C, Fu XM, Xu RF, Zheng JJ, Zhao DL, She ZG, Wang CY. Bioactive indole alkaloids and phenyl ether derivatives from a marine-derived Aspergillus sp. Fungus. J Nat Prod. 2013 Apr 26; 76(4):547-53. PMID: 23527875.
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      47. Zhao HY, Shao C, Li ZY, Han L, Cao F, Wang CY. Bioactive pregnane steroids from a South China Sea gorgonian Carijoa sp. Molecules. 2013 Mar 15; 18(3):3458-66. PMID: 23503119.
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      48. Qi J, Shao C, Li ZY, Gan LS, Fu XM, Bian WT, Zhao HY, Wang CY. Isocoumarin derivatives and benzofurans from a sponge-derived Penicillium sp. fungus. J Nat Prod. 2013 Apr 26; 76(4):571-9. PMID: 23477451.
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      49. Sun LL, Shao C, Hang H, Guo ZY, Xing Q, Wang CY. New polyhydroxylated steroid from the South China Sea gorgonian Anthogorgia caerulea. Nat Prod Res. 2013; 27(13):1159-66. PMID: 22946558.
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      50. Li R, Shao C, Qi X, Li XB, Li J, Sun LL, Wang CY. Polyoxygenated sterols from the South China Sea soft coral Sinularia sp. Mar Drugs. 2012 Jul; 10(7):1422-32. PMID: 22851916; PMCID: PMC3407921.
      51. Yang KL, Wei MY, Shao C, Fu XM, Guo ZY, Xu RF, Zheng CJ, She ZG, Lin YC, Wang CY. Antibacterial anthraquinone derivatives from a sea anemone-derived fungus Nigrospora sp. J Nat Prod. 2012 May 25; 75(5):935-41. PMID: 22545792.
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      52. Xiao R, Tang P, Yang B, Huang J, Zhou Y, Shao C, Li H, Sun H, Zhang Y, Fu XD. Nuclear matrix factor hnRNP U/SAF-A exerts a global control of alternative splicing by regulating U2 snRNP maturation. Mol Cell. 2012 Mar 09; 45(5):656-68. PMID: 22325991; PMCID: PMC3299905.
      53. Zheng CJ, Shao C, Guo ZY, Chen JF, Deng DS, Yang KL, Chen YY, Fu XM, She ZG, Lin YC, Wang CY. Bioactive hydroanthraquinones and anthraquinone dimers from a soft coral-derived Alternaria sp. fungus. J Nat Prod. 2012 Feb 24; 75(2):189-97. PMID: 22276679.
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      54. Li D, Xu Y, Shao C, Yang RY, Zheng CJ, Chen YY, Fu XM, Qian PY, She ZG, de Voogd NJ, Wang CY. Antibacterial bisabolane-type sesquiterpenoids from the sponge-derived fungus Aspergillus sp. Mar Drugs. 2012 Jan; 10(1):234-41. PMID: 22363233; PMCID: PMC3280534.
      55. Sun LL, Shao C, Chen JF, Guo ZY, Fu XM, Chen M, Chen YY, Li R, de Voogd NJ, She ZG, Lin YC, Wang CY. New bisabolane sesquiterpenoids from a marine-derived fungus Aspergillus sp. isolated from the sponge Xestospongia testudinaria. Bioorg Med Chem Lett. 2012 Feb 01; 22(3):1326-9. PMID: 22225637.
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      56. Zhou YM, Shao C, Wang CY, Huang H, Xu Y, Qian PY. Chemical constituents of the Gorgonian Dichotella fragilis (Ridleg) from the South China Sea. Nat Prod Commun. 2011 Sep; 6(9):1239-42. PMID: 21941887.
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      57. Wang YN, Shao C, Zheng CJ, Chen YY, Wang CY. Diversity and antibacterial activities of fungi derived from the Gorgonian Echinogorgia rebekka from the South China Sea. Mar Drugs. 2011; 9(8):1379-90. PMID: 21892352; PMCID: PMC3164380.
      58. Shao C, Wang X, Zhang Q, Luo S, Zhao J, Hu Y. Acid-base jointly promoted copper(I)-catalyzed azide-alkyne cycloaddition. J Org Chem. 2011 Aug 19; 76(16):6832-6. PMID: 21793533.
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      59. Cheng G, Wang X, Zhu R, Shao C, Xu J, Hu Y. Total synthesis of (-)-cocaine and (-)-ferruginine. J Org Chem. 2011 Apr 15; 76(8):2694-700. PMID: 21391709.
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      60. Shao C, Wu HX, Wang CY, Liu QA, Xu Y, Wei MY, Qian PY, Gu YC, Zheng CJ, She ZG, Lin YC. Potent antifouling resorcylic acid lactones from the gorgonian-derived fungus Cochliobolus lunatus. J Nat Prod. 2011 Apr 25; 74(4):629-33. PMID: 21348465.
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      61. Shao C, Wang CY, Wei MY, Gu YC, She ZG, Qian PY, Lin YC. Aspergilones A and B, two benzylazaphilones with an unprecedented carbon skeleton from the gorgonian-derived fungus Aspergillus sp. Bioorg Med Chem Lett. 2011 Jan 15; 21(2):690-3. PMID: 21194945.
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      62. Su D, Wang X, Shao C, Xu J, Zhu R, Hu Y. Total synthesis of (+)-epilupinine via an intramolecular nitrile oxide-alkene cycloaddition. J Org Chem. 2011 Jan 07; 76(1):188-94. PMID: 21121617.
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      63. Wang CY, Zhao J, Liu HY, Shao C, Liu QA, Liu Y, Gu YC. Two new eicosanoids with a unique isovalerianic acid ester moiety from the South China Sea gorgonian Dichotella gemmacea. Lipids. 2011 Jan; 46(1):81-5. PMID: 21080235.
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      64. Shao C, Wang X, Xu J, Zhao J, Zhang Q, Hu Y. Carboxylic acid-promoted copper(I)-catalyzed azide-alkyne cycloaddition. J Org Chem. 2010 Oct 15; 75(20):7002-5. PMID: 20849130.
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      65. Sun XP, Wang CY, Shao C, Li L, Li XB, Chen M, Qian PY. Chemical constituents of the soft coral Sarcophyton infundibuliforme from the South China Sea. Nat Prod Commun. 2010 Aug; 5(8):1171-4. PMID: 20839611.
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      66. Shao C, Wang CY, Gu YC, Wei MY, Pan JH, Deng DS, She ZG, Lin YC. Penicinoline, a new pyrrolyl 4-quinolinone alkaloid with an unprecedented ring system from an endophytic fungus Penicillium sp. Bioorg Med Chem Lett. 2010 Jun 01; 20(11):3284-6. PMID: 20452770.
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      67. Wei MY, Wang CY, Liu QA, Shao C, She ZG, Lin YC. Five sesquiterpenoids from a marine-derived fungus Aspergillus sp. isolated from a gorgonian Dichotella gemmacea. Mar Drugs. 2010 Mar 29; 8(4):941-9. PMID: 20479961; PMCID: PMC2866469.
      68. Li L, Wang CY, Shao C, Han L, Sun XP, Zhao J, Guo YW, Huang H, Guan HS. Two new metabolites from the Hainan soft coral Sarcophyton crassocaule. J Asian Nat Prod Res. 2009 Oct; 11(10):851-5. PMID: 20183245.
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      69. Shao C, Han L, Li CY, Liu Z, Wang CY. 6,8-Dihydr-oxy-3-methyl-isocoumarin. Acta Crystallogr Sect E Struct Rep Online. 2009 Mar 11; 65(Pt 4):o736. PMID: 21582469; PMCID: PMC2968904.
      70. Wei MY, Liu Z, Zhang XL, Shao C, Wang CY. Methyl 3-hydr-oxy-4-(3-methyl-but-2-en-yloxy)benzoate. Acta Crystallogr Sect E Struct Rep Online. 2009 Mar 11; 65(Pt 4):o734-5. PMID: 21582468; PMCID: PMC2968826.
      71. Wei MY, Liu Z, Shao C, Jia ZB, Wang CY. 3-Hydroxy-meth-yl-6,8-dimeth-oxy-2H-chromen-2-one. Acta Crystallogr Sect E Struct Rep Online. 2008 Jun 07; 64(Pt 7):o1189. PMID: 21202831; PMCID: PMC2961715.
      72. Shao C, Li C, Liu Z, Wei MY, Wang CY. 1,3-Bis(chloro-meth-yl)-2-methyl-5-nitro-benzene. Acta Crystallogr Sect E Struct Rep Online. 2008 Mar 20; 64(Pt 4):o731. PMID: 21202121; PMCID: PMC2960992.
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