Brian Chen

Title(s)Assistant Adjunct Professor, Herbert Wertheim School of Public Health & Human Longevity Science
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
ORCID ORCID Icon0000-0001-9065-3301 Additional info
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    Collapse Biography 
    Collapse Education and Training
    UCLA, Los Angeles, CAPhDEpidemiology
    UC Berkeley, Berkeley, CAMPHEpidemiology/Biostatistics
    UC San Diego, La Jolla, CA B.S.Biochemistry/Cell Biology & Psychology

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Animal Models Relevant for Geroscience: Current Trends and Future Perspectives in Biomarkers, and Measures of Biological Aging. J Gerontol A Biol Sci Med Sci. 2024 Sep 01; 79(9). Bartolomucci A, Kane AE, Gaydosh L, Razzoli M, McCoy BM, Ehninger D, Chen BH, Howlett SE, Snyder-Mackler N. PMID: 39126297; PMCID: PMC11316208.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    2. Validation of biomarkers of aging. Nat Med. 2024 Feb; 30(2):360-372. Moqri M, Herzog C, Poganik JR, Ying K, Justice JN, Belsky DW, Higgins-Chen AT, Chen BH, Cohen AA, Fuellen G, Hägg S, Marioni RE, Widschwendter M, Fortney K, Fedichev PO, Zhavoronkov A, Barzilai N, Lasky-Su J, Kiel DP, Kennedy BK, Cummings S, Slagboom PE, Verdin E, Maier AB, Sebastiano V, Snyder MP, Gladyshev VN, Horvath S, Ferrucci L. PMID: 38355974; PMCID: PMC11090477.
      View in: PubMed   Mentions: 12     Fields:    
    3. Association of Epigenetic Age Acceleration With Incident Mild Cognitive Impairment and Dementia Among Older Women. J Gerontol A Biol Sci Med Sci. 2022 06 01; 77(6):1239-1244. Shadyab AH, McEvoy LK, Horvath S, Whitsel EA, Rapp SR, Espeland MA, Resnick SM, Manson JE, Chen JC, Chen BH, Li W, Hayden KM, Bao W, Kusters CDJ, LaCroix AZ. PMID: 34417803; PMCID: PMC9159659.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    4. Predicting physiological aging rates from a range of quantitative traits using machine learning. Aging (Albany NY). 2021 10 29; 13(20):23471-23516. Sun ED, Qian Y, Oppong R, Butler TJ, Zhao J, Chen BH, Tanaka T, Kang J, Sidore C, Cucca F, Bandinelli S, Abecasis GR, Gorospe M, Ferrucci L, Schlessinger D, Goldberg I, Ding J. PMID: 34718232; PMCID: PMC8580337.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    5. Epigenetic moderators of naltrexone efficacy in reducing heavy drinking in Alcohol Use Disorder: a randomized trial. Pharmacogenomics J. 2022 02; 22(1):1-8. Schacht JP, Hoffman M, Chen BH, Anton RF. PMID: 34381173; PMCID: PMC8799481.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    6. The 2020 FASEB virtual Catalyst Conference on Integrative Approach for Complex Diseases Prevention and Management and Beyond, December 16, 2020. FASEB J. 2021 07; 35(7):e21500. Chan KHK, Hsu YH, Yang X, Goto A, Chen BH. PMID: 34165815.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    7. The trans-ancestral genomic architecture of glycemic traits. Nat Genet. 2021 06; 53(6):840-860. Chen J, Spracklen CN, Marenne G, Varshney A, Corbin LJ, Luan J, Willems SM, Wu Y, Zhang X, Horikoshi M, Boutin TS, Mägi R, Waage J, Li-Gao R, Chan KHK, Yao J, Anasanti MD, Chu AY, Claringbould A, Heikkinen J, Hong J, Hottenga JJ, Huo S, Kaakinen MA, Louie T, März W, Moreno-Macias H, Ndungu A, Nelson SC, Nolte IM, North KE, Raulerson CK, Ray D, Rohde R, Rybin D, Schurmann C, Sim X, Southam L, Stewart ID, Wang CA, Wang Y, Wu P, Zhang W, Ahluwalia TS, Appel EVR, Bielak LF, Brody JA, Burtt NP, Cabrera CP, Cade BE, Chai JF, Chai X, Chang LC, Chen CH, Chen BH, Chitrala KN, Chiu YF, de Haan HG, Delgado GE, Demirkan A, Duan Q, Engmann J, Fatumo SA, Gayán J, Giulianini F, Gong JH, Gustafsson S, Hai Y, Hartwig FP, He J, Heianza Y, Huang T, Huerta-Chagoya A, Hwang MY, Jensen RA, Kawaguchi T, Kentistou KA, Kim YJ, Kleber ME, Kooner IK, Lai S, Lange LA, Langefeld CD, Lauzon M, Li M, Ligthart S, Liu J, Loh M, Long J, Lyssenko V, Mangino M, Marzi C, Montasser ME, Nag A, Nakatochi M, Noce D, Noordam R, Pistis G, Preuss M, Raffield L, Rasmussen-Torvik LJ, Rich SS, Robertson NR, Rueedi R, Ryan K, Sanna S, Saxena R, Schraut KE, Sennblad B, Setoh K, Smith AV, Sparsø T, Strawbridge RJ, Takeuchi F, Tan J, Trompet S, van den Akker E, van der Most PJ, Verweij N, Vogel M, Wang H, Wang C, Wang N, Warren HR, Wen W, Wilsgaard T, Wong A, Wood AR, Xie T, Zafarmand MH, Zhao JH, Zhao W, Amin N, Arzumanyan Z, Astrup A, Bakker SJL, Baldassarre D, Beekman M, Bergman RN, Bertoni A, Blüher M, Bonnycastle LL, Bornstein SR, Bowden DW, Cai Q, Campbell A, Campbell H, Chang YC, de Geus EJC, Dehghan A, Du S, Eiriksdottir G, Farmaki AE, Frånberg M, Fuchsberger C, Gao Y, Gjesing AP, Goel A, Han S, Hartman CA, Herder C, Hicks AA, Hsieh CH, Hsueh WA, Ichihara S, Igase M, Ikram MA, Johnson WC, Jørgensen ME, Joshi PK, Kalyani RR, Kandeel FR, Katsuya T, Khor CC, Kiess W, Kolcic I, Kuulasmaa T, Kuusisto J, Läll K, Lam K, Lawlor DA, Lee NR, Lemaitre RN, Li H, Lifelines Cohort Study, Lin SY, Lindström J, Linneberg A, Liu J, Lorenzo C, Matsubara T, Matsuda F, Mingrone G, Mooijaart S, Moon S, Nabika T, Nadkarni GN, Nadler JL, Nelis M, Neville MJ, Norris JM, Ohyagi Y, Peters A, Peyser PA, Polasek O, Qi Q, Raven D, Reilly DF, Reiner A, Rivideneira F, Roll K, Rudan I, Sabanayagam C, Sandow K, Sattar N, Schürmann A, Shi J, Stringham HM, Taylor KD, Teslovich TM, Thuesen B, Timmers PRHJ, Tremoli E, Tsai MY, Uitterlinden A, van Dam RM, van Heemst D, van Hylckama Vlieg A, van Vliet-Ostaptchouk JV, Vangipurapu J, Vestergaard H, Wang T, Willems van Dijk K, Zemunik T, Abecasis GR, Adair LS, Aguilar-Salinas CA, Alarcón-Riquelme ME, An P, Aviles-Santa L, Becker DM, Beilin LJ, Bergmann S, Bisgaard H, Black C, Boehnke M, Boerwinkle E, Böhm BO, Bønnelykke K, Boomsma DI, Bottinger EP, Buchanan TA, Canouil M, Caulfield MJ, Chambers JC, Chasman DI, Chen YI, Cheng CY, Collins FS, Correa A, Cucca F, de Silva HJ, Dedoussis G, Elmståhl S, Evans MK, Ferrannini E, Ferrucci L, Florez JC, Franks PW, Frayling TM, Froguel P, Gigante B, Goodarzi MO, Gordon-Larsen P, Grallert H, Grarup N, Grimsgaard S, Groop L, Gudnason V, Guo X, Hamsten A, Hansen T, Hayward C, Heckbert SR, Horta BL, Huang W, Ingelsson E, James PS, Jarvelin MR, Jonas JB, Jukema JW, Kaleebu P, Kaplan R, Kardia SLR, Kato N, Keinanen-Kiukaanniemi SM, Kim BJ, Kivimaki M, Koistinen HA, Kooner JS, Körner A, Kovacs P, Kuh D, Kumari M, Kutalik Z, Laakso M, Lakka TA, Launer LJ, Leander K, Li H, Lin X, Lind L, Lindgren C, Liu S, Loos RJF, Magnusson PKE, Mahajan A, Metspalu A, Mook-Kanamori DO, Mori TA, Munroe PB, Njølstad I, O'Connell JR, Oldehinkel AJ, Ong KK, Padmanabhan S, et al. PMID: 34059833; PMCID: PMC7610958.
      View in: PubMed   Mentions: 223     Fields:    Translation:Humans
    8. Blood Leukocyte DNA Methylation Predicts Risk of Future Myocardial Infarction and Coronary Heart Disease. Circulation. 2019 08 20; 140(8):645-657. Agha G, Mendelson MM, Ward-Caviness CK, Joehanes R, Huan T, Gondalia R, Salfati E, Brody JA, Fiorito G, Bressler J, Chen BH, Ligthart S, Guarrera S, Colicino E, Just AC, Wahl S, Gieger C, Vandiver AR, Tanaka T, Hernandez DG, Pilling LC, Singleton AB, Sacerdote C, Krogh V, Panico S, Tumino R, Li Y, Zhang G, Stewart JD, Floyd JS, Wiggins KL, Rotter JI, Multhaup M, Bakulski K, Horvath S, Tsao PS, Absher DM, Vokonas P, Hirschhorn J, Fallin MD, Liu C, Bandinelli S, Boerwinkle E, Dehghan A, Schwartz JD, Psaty BM, Feinberg AP, Hou L, Ferrucci L, Sotoodehnia N, Matullo G, Peters A, Fornage M, Assimes TL, Whitsel EA, Levy D, Baccarelli AA. PMID: 31424985; PMCID: PMC6812683.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansCells
    9. Novel age-associated DNA methylation changes and epigenetic age acceleration in middle-aged African Americans and whites. Clin Epigenetics. 2019 08 19; 11(1):119. Tajuddin SM, Hernandez DG, Chen BH, Noren Hooten N, Mode NA, Nalls MA, Singleton AB, Ejiogu N, Chitrala KN, Zonderman AB, Evans MK. PMID: 31426852; PMCID: PMC6700815.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    10. The role of epigenetic aging in education and racial/ethnic mortality disparities among older U.S. Women. Psychoneuroendocrinology. 2019 06; 104:18-24. Liu Z, Chen BH, Assimes TL, Ferrucci L, Horvath S, Levine ME. PMID: 30784901; PMCID: PMC6555423.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    11. Epigenetic age is a cell-intrinsic property in transplanted human hematopoietic cells. Aging Cell. 2019 04; 18(2):e12897. Søraas A, Matsuyama M, de Lima M, Wald D, Buechner J, Gedde-Dahl T, Søraas CL, Chen B, Ferrucci L, Dahl JA, Horvath S, Matsuyama S. PMID: 30712319; PMCID: PMC6413751.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    12. Tracking the Epigenetic Clock Across the Human Life Course: A Meta-analysis of Longitudinal Cohort Data. J Gerontol A Biol Sci Med Sci. 2019 01 01; 74(1):57-61. Marioni RE, Suderman M, Chen BH, Horvath S, Bandinelli S, Morris T, Beck S, Ferrucci L, Pedersen NL, Relton CL, Deary IJ, Hägg S. PMID: 29718110; PMCID: PMC6298183.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    13. Analysis of repeated leukocyte DNA methylation assessments reveals persistent epigenetic alterations after an incident myocardial infarction. Clin Epigenetics. 2018 12 27; 10(1):161. Ward-Caviness CK, Agha G, Chen BH, Pfeiffer L, Wilson R, Wolf P, Gieger C, Schwartz J, Vokonas PS, Hou L, Just AC, Bandinelli S, Hernandez DG, Singleton AB, Prokisch H, Meitinger T, Kastenmüller G, Ferrucci L, Baccarelli AA, Waldenberger M, Peters A. PMID: 30587240; PMCID: PMC6307146.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    14. An epigenetic biomarker of aging for lifespan and healthspan. Aging (Albany NY). 2018 04 18; 10(4):573-591. Levine ME, Lu AT, Quach A, Chen BH, Assimes TL, Bandinelli S, Hou L, Baccarelli AA, Stewart JD, Li Y, Whitsel EA, Wilson JG, Reiner AP, Aviv A, Lohman K, Liu Y, Ferrucci L, Horvath S. PMID: 29676998; PMCID: PMC5940111.
      View in: PubMed   Mentions: 1012     Fields:    Translation:Humans
    15. Genetic variants in sex hormone pathways and the risk of type 2 diabetes among African American, Hispanic American, and European American postmenopausal women in the US. J Diabetes. 2018 Jun; 10(6):524-533. Goto A, Chen BH, Chan KK, Lee C, Nelson SC, Crenshaw A, Bookman E, Margolis KL, Sale MM, MEta-analysis of type 2 DIabetes in African Americans (MEDIA) Consortium, Ng MCY, Reiner AP, Liu S. PMID: 29417738; PMCID: PMC5980699.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    16. GWAS of epigenetic aging rates in blood reveals a critical role for TERT. Nat Commun. 2018 01 26; 9(1):387. Lu AT, Xue L, Salfati EL, Chen BH, Ferrucci L, Levy D, Joehanes R, Murabito JM, Kiel DP, Tsai PC, Yet I, Bell JT, Mangino M, Tanaka T, McRae AF, Marioni RE, Visscher PM, Wray NR, Deary IJ, Levine ME, Quach A, Assimes T, Tsao PS, Absher D, Stewart JD, Li Y, Reiner AP, Hou L, Baccarelli AA, Whitsel EA, Aviv A, Cardona A, Day FR, Wareham NJ, Perry JRB, Ong KK, Raj K, Lunetta KL, Horvath S. PMID: 29374233; PMCID: PMC5786029.
      View in: PubMed   Mentions: 105     Fields:    Translation:HumansCells
    17. Skeletal muscle ex vivo mitochondrial respiration parallels decline in vivo oxidative capacity, cardiorespiratory fitness, and muscle strength: The Baltimore Longitudinal Study of Aging. Aging Cell. 2018 04; 17(2). Gonzalez-Freire M, Scalzo P, D'Agostino J, Moore ZA, Diaz-Ruiz A, Fabbri E, Zane A, Chen B, Becker KG, Lehrmann E, Zukley L, Chia CW, Tanaka T, Coen PM, Bernier M, de Cabo R, Ferrucci L. PMID: 29356348; PMCID: PMC5847858.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansCells
    18. Age-associated microRNA expression in human peripheral blood is associated with all-cause mortality and age-related traits. Aging Cell. 2018 02; 17(1). Huan T, Chen G, Liu C, Bhattacharya A, Rong J, Chen BH, Seshadri S, Tanriverdi K, Freedman JE, Larson MG, Murabito JM, Levy D. PMID: 29044988; PMCID: PMC5770777.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansCells
    19. Leukocyte telomere length, T cell composition and DNA methylation age. Aging (Albany NY). 2017 09 20; 9(9):1983-1995. Chen BH, Carty CL, Kimura M, Kark JD, Chen W, Li S, Zhang T, Kooperberg C, Levy D, Assimes T, Absher D, Horvath S, Reiner AP, Aviv A. PMID: 28930701; PMCID: PMC5636670.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    20. Relationships of sex hormone levels with leukocyte telomere length in Black, Hispanic, and Asian/Pacific Islander postmenopausal women. J Diabetes. 2018 Jun; 10(6):502-511. Song Y, Cho M, Brennan KM, Chen BH, Song Y, Manson JE, Hevener AL, You NY, Butch AW, Liu S. PMID: 28609023; PMCID: PMC6499547.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    21. Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms. Cell. 2017 Jun 29; 170(1):199-212.e20. Rusu V, Hoch E, Mercader JM, Tenen DE, Gymrek M, Hartigan CR, DeRan M, von Grotthuss M, Fontanillas P, Spooner A, Guzman G, Deik AA, Pierce KA, Dennis C, Clish CB, Carr SA, Wagner BK, Schenone M, Ng MCY, Chen BH, MEDIA Consortium, SIGMA T2D Consortium, Centeno-Cruz F, Zerrweck C, Orozco L, Altshuler DM, Schreiber SL, Florez JC, Jacobs SBR, Lander ES. PMID: 28666119; PMCID: PMC5562285.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansCells
    22. Epigenetic clock analysis of diet, exercise, education, and lifestyle factors. Aging (Albany NY). 2017 02 14; 9(2):419-446. Quach A, Levine ME, Tanaka T, Lu AT, Chen BH, Ferrucci L, Ritz B, Bandinelli S, Neuhouser ML, Beasley JM, Snetselaar L, Wallace RB, Tsao PS, Absher D, Assimes TL, Stewart JD, Li Y, Hou L, Baccarelli AA, Whitsel EA, Horvath S. PMID: 28198702; PMCID: PMC5361673.
      View in: PubMed   Mentions: 328     Fields:    Translation:Humans
    23. Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach. PLoS Med. 2017 Jan; 14(1):e1002215. Mendelson MM, Marioni RE, Joehanes R, Liu C, Hedman ÅK, Aslibekyan S, Demerath EW, Guan W, Zhi D, Yao C, Huan T, Willinger C, Chen B, Courchesne P, Multhaup M, Irvin MR, Cohain A, Schadt EE, Grove ML, Bressler J, North K, Sundström J, Gustafsson S, Shah S, McRae AF, Harris SE, Gibson J, Redmond P, Corley J, Murphy L, Starr JM, Kleinbrink E, Lipovich L, Visscher PM, Wray NR, Krauss RM, Fallin D, Feinberg A, Absher DM, Fornage M, Pankow JS, Lind L, Fox C, Ingelsson E, Arnett DK, Boerwinkle E, Liang L, Levy D, Deary IJ. PMID: 28095459; PMCID: PMC5240936.
      View in: PubMed   Mentions: 149     Fields:    Translation:HumansCells
    24. DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases. Genome Biol. 2016 12 12; 17(1):255. Ligthart S, Marzi C, Aslibekyan S, Mendelson MM, Conneely KN, Tanaka T, Colicino E, Waite LL, Joehanes R, Guan W, Brody JA, Elks C, Marioni R, Jhun MA, Agha G, Bressler J, Ward-Caviness CK, Chen BH, Huan T, Bakulski K, Salfati EL, WHI-EMPC Investigators, Fiorito G, CHARGE epigenetics of Coronary Heart Disease, Wahl S, Schramm K, Sha J, Hernandez DG, Just AC, Smith JA, Sotoodehnia N, Pilling LC, Pankow JS, Tsao PS, Liu C, Zhao W, Guarrera S, Michopoulos VJ, Smith AK, Peters MJ, Melzer D, Vokonas P, Fornage M, Prokisch H, Bis JC, Chu AY, Herder C, Grallert H, Yao C, Shah S, McRae AF, Lin H, Horvath S, Fallin D, Hofman A, Wareham NJ, Wiggins KL, Feinberg AP, Starr JM, Visscher PM, Murabito JM, Kardia SL, Absher DM, Binder EB, Singleton AB, Bandinelli S, Peters A, Waldenberger M, Matullo G, Schwartz JD, Demerath EW, Uitterlinden AG, van Meurs JB, Franco OH, Chen YI, Levy D, Turner ST, Deary IJ, Ressler KJ, Dupuis J, Ferrucci L, Ong KK, Assimes TL, Boerwinkle E, Koenig W, Arnett DK, Baccarelli AA, Benjamin EJ, Dehghan A. PMID: 27955697; PMCID: PMC5151130.
      View in: PubMed   Mentions: 156     Fields:    Translation:HumansCells
    25. DNA methylation-based measures of biological age: meta-analysis predicting time to death. Aging (Albany NY). 2016 09 28; 8(9):1844-1865. Chen BH, Marioni RE, Colicino E, Peters MJ, Ward-Caviness CK, Tsai PC, Roetker NS, Just AC, Demerath EW, Guan W, Bressler J, Fornage M, Studenski S, Vandiver AR, Moore AZ, Tanaka T, Kiel DP, Liang L, Vokonas P, Schwartz J, Lunetta KL, Murabito JM, Bandinelli S, Hernandez DG, Melzer D, Nalls M, Pilling LC, Price TR, Singleton AB, Gieger C, Holle R, Kretschmer A, Kronenberg F, Kunze S, Linseisen J, Meisinger C, Rathmann W, Waldenberger M, Visscher PM, Shah S, Wray NR, McRae AF, Franco OH, Hofman A, Uitterlinden AG, Absher D, Assimes T, Levine ME, Lu AT, Tsao PS, Hou L, Manson JE, Carty CL, LaCroix AZ, Reiner AP, Spector TD, Feinberg AP, Levy D, Baccarelli A, van Meurs J, Bell JT, Peters A, Deary IJ, Pankow JS, Ferrucci L, Horvath S. PMID: 27690265; PMCID: PMC5076441.
      View in: PubMed   Mentions: 495     Fields:    Translation:HumansCells
    26. Peripheral Blood Transcriptomic Signatures of Fasting Glucose and Insulin Concentrations. Diabetes. 2016 Dec; 65(12):3794-3804. Chen BH, Hivert MF, Peters MJ, Pilling LC, Hogan JD, Pham LM, Harries LW, Fox CS, Bandinelli S, Dehghan A, Hernandez DG, Hofman A, Hong J, Joehanes R, Johnson AD, Munson PJ, Rybin DV, Singleton AB, Uitterlinden AG, Ying S, MAGIC Investigators, Melzer D, Levy D, van Meurs JB, Ferrucci L, Florez JC, Dupuis J, Meigs JB, Kolaczyk ED. PMID: 27625022; PMCID: PMC5127245.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    27. An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease. Genome Biol. 2016 08 11; 17(1):171. Horvath S, Gurven M, Levine ME, Trumble BC, Kaplan H, Allayee H, Ritz BR, Chen B, Lu AT, Rickabaugh TM, Jamieson BD, Sun D, Li S, Chen W, Quintana-Murci L, Fagny M, Kobor MS, Tsao PS, Reiner AP, Edlefsen KL, Absher D, Assimes TL. PMID: 27511193; PMCID: PMC4980791.
      View in: PubMed   Mentions: 340     Fields:    Translation:HumansCells
    28. Menopause accelerates biological aging. Proc Natl Acad Sci U S A. 2016 08 16; 113(33):9327-32. Levine ME, Lu AT, Chen BH, Hernandez DG, Singleton AB, Ferrucci L, Bandinelli S, Salfati E, Manson JE, Quach A, Kusters CD, Kuh D, Wong A, Teschendorff AE, Widschwendter M, Ritz BR, Absher D, Assimes TL, Horvath S. PMID: 27457926; PMCID: PMC4995944.
      View in: PubMed   Mentions: 183     Fields:    Translation:Humans
    29. Metabolite Signatures of Metabolic Risk Factors and their Longitudinal Changes. J Clin Endocrinol Metab. 2016 04; 101(4):1779-89. Yin X, Subramanian S, Willinger CM, Chen G, Juhasz P, Courchesne P, Chen BH, Li X, Hwang SJ, Fox CS, O'Donnell CJ, Muntendam P, Fuster V, Bobeldijk-Pastorova I, Sookoian SC, Pirola CJ, Gordon N, Adourian A, Larson MG, Levy D. PMID: 26908103; PMCID: PMC4880163.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    30. DNA methylation age of blood predicts future onset of lung cancer in the women's health initiative. Aging (Albany NY). 2015 Sep; 7(9):690-700. Levine ME, Hosgood HD, Chen B, Absher D, Assimes T, Horvath S. PMID: 26411804; PMCID: PMC4600626.
      View in: PubMed   Mentions: 170     Fields:    Translation:HumansCells
    31. Integrative network analysis reveals molecular mechanisms of blood pressure regulation. Mol Syst Biol. 2015 Apr 16; 11(1):799. Huan T, Meng Q, Saleh MA, Norlander AE, Joehanes R, Zhu J, Chen BH, Zhang B, Johnson AD, Ying S, Courchesne P, Raghavachari N, Wang R, Liu P, International Consortium for Blood Pressure GWAS (ICBP), O'Donnell CJ, Vasan R, Munson PJ, Madhur MS, Harrison DG, Yang X, Levy D. PMID: 25882670; PMCID: PMC4422556.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    32. Genome-wide identification of microRNA expression quantitative trait loci. Nat Commun. 2015 Mar 20; 6:6601. Huan T, Rong J, Liu C, Zhang X, Tanriverdi K, Joehanes R, Chen BH, Murabito JM, Yao C, Courchesne P, Munson PJ, O'Donnell CJ, Cox N, Johnson AD, Larson MG, Levy D, Freedman JE. PMID: 25791433; PMCID: PMC4369777.
      View in: PubMed   Mentions: 83     Fields:    Translation:HumansCells
    33. A meta-analysis of gene expression signatures of blood pressure and hypertension. PLoS Genet. 2015 Mar; 11(3):e1005035. Huan T, Esko T, Peters MJ, Pilling LC, Schramm K, Schurmann C, Chen BH, Liu C, Joehanes R, Johnson AD, Yao C, Ying SX, Courchesne P, Milani L, Raghavachari N, Wang R, Liu P, Reinmaa E, Dehghan A, Hofman A, Uitterlinden AG, Hernandez DG, Bandinelli S, Singleton A, Melzer D, Metspalu A, Carstensen M, Grallert H, Herder C, Meitinger T, Peters A, Roden M, Waldenberger M, Dörr M, Felix SB, Zeller T, International Consortium for Blood Pressure GWAS (ICBP), Vasan R, O'Donnell CJ, Munson PJ, Yang X, Prokisch H, Völker U, van Meurs JB, Ferrucci L, Levy D. PMID: 25785607; PMCID: PMC4365001.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansCells
    34. Identification of common genetic variants controlling transcript isoform variation in human whole blood. Nat Genet. 2015 Apr; 47(4):345-52. Zhang X, Joehanes R, Chen BH, Huan T, Ying S, Munson PJ, Johnson AD, Levy D, O'Donnell CJ. PMID: 25685889; PMCID: PMC8273720.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    35. DNA methylation age of blood predicts all-cause mortality in later life. Genome Biol. 2015 Jan 30; 16:25. Marioni RE, Shah S, McRae AF, Chen BH, Colicino E, Harris SE, Gibson J, Henders AK, Redmond P, Cox SR, Pattie A, Corley J, Murphy L, Martin NG, Montgomery GW, Feinberg AP, Fallin MD, Multhaup ML, Jaffe AE, Joehanes R, Schwartz J, Just AC, Lunetta KL, Murabito JM, Starr JM, Horvath S, Baccarelli AA, Levy D, Visscher PM, Wray NR, Deary IJ. PMID: 25633388; PMCID: PMC4350614.
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    36. A systematic heritability analysis of the human whole blood transcriptome. Hum Genet. 2015 Mar; 134(3):343-58. Huan T, Liu C, Joehanes R, Zhang X, Chen BH, Johnson AD, Yao C, Courchesne P, O'Donnell CJ, Munson PJ, Levy D. PMID: 25585846; PMCID: PMC4339826.
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    37. Integromic analysis of genetic variation and gene expression identifies networks for cardiovascular disease phenotypes. Circulation. 2015 Feb 10; 131(6):536-49. Yao C, Chen BH, Joehanes R, Otlu B, Zhang X, Liu C, Huan T, Tastan O, Cupples LA, Meigs JB, Fox CS, Freedman JE, Courchesne P, O'Donnell CJ, Munson PJ, Keles S, Levy D. PMID: 25533967; PMCID: PMC4369387.
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    38. Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes. PLoS Genet. 2014 Aug; 10(8):e1004517. Ng MC, Shriner D, Chen BH, Li J, Chen WM, Guo X, Liu J, Bielinski SJ, Yanek LR, Nalls MA, Comeau ME, Rasmussen-Torvik LJ, Jensen RA, Evans DS, Sun YV, An P, Patel SR, Lu Y, Long J, Armstrong LL, Wagenknecht L, Yang L, Snively BM, Palmer ND, Mudgal P, Langefeld CD, Keene KL, Freedman BI, Mychaleckyj JC, Nayak U, Raffel LJ, Goodarzi MO, Chen YD, Taylor HA, Correa A, Sims M, Couper D, Pankow JS, Boerwinkle E, Adeyemo A, Doumatey A, Chen G, Mathias RA, Vaidya D, Singleton AB, Zonderman AB, Igo RP, Sedor JR, FIND Consortium, Kabagambe EK, Siscovick DS, McKnight B, Rice K, Liu Y, Hsueh WC, Zhao W, Bielak LF, Kraja A, Province MA, Bottinger EP, Gottesman O, Cai Q, Zheng W, Blot WJ, Lowe WL, Pacheco JA, Crawford DC, eMERGE Consortium, DIAGRAM Consortium, Grundberg E, MuTHER Consortium, Rich SS, Hayes MG, Shu XO, Loos RJ, Borecki IB, Peyser PA, Cummings SR, Psaty BM, Fornage M, Iyengar SK, Evans MK, Becker DM, Kao WH, Wilson JG, Rotter JI, Sale MM, Liu S, Rotimi CN, Bowden DW, MEta-analysis of type 2 DIabetes in African Americans Consortium. PMID: 25102180; PMCID: PMC4125087.
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    39. Epigenome-wide association study of fasting blood lipids in the Genetics of Lipid-lowering Drugs and Diet Network study. Circulation. 2014 Aug 12; 130(7):565-72. Irvin MR, Zhi D, Joehanes R, Mendelson M, Aslibekyan S, Claas SA, Thibeault KS, Patel N, Day K, Jones LW, Liang L, Chen BH, Yao C, Tiwari HK, Ordovas JM, Levy D, Absher D, Arnett DK. PMID: 24920721; PMCID: PMC4209699.
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    40. Effects of varying doses of testosterone on atherogenic markers in healthy younger and older men. Am J Physiol Regul Integr Comp Physiol. 2014 Jan 15; 306(2):R118-23. Roberts CK, Chen BH, Pruthi S, Lee ML. PMID: 24305063.
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    41. Age, body mass, usage of exogenous estrogen, and lifestyle factors in relation to circulating sex hormone-binding globulin concentrations in postmenopausal women. Clin Chem. 2014 Jan; 60(1):174-85. Goto A, Chen BH, Song Y, Cauley J, Cummings SR, Farhat GN, Gunter M, Van Horn L, Howard BV, Jackson R, Lee J, Rexrode KM, Liu S. PMID: 24048437.
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    42. Sex hormone-binding globulin and risk of clinical diabetes in American black, Hispanic, and Asian/Pacific Islander postmenopausal women. Clin Chem. 2012 Oct; 58(10):1457-66. Chen BH, Brennan K, Goto A, Song Y, Aziz N, You NC, Wellons MF, Manson JE, White DL, Butch AW, Liu S. PMID: 22908136; PMCID: PMC4088986.
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    43. A prospective study of leukocyte telomere length and risk of type 2 diabetes in postmenopausal women. Diabetes. 2012 Nov; 61(11):2998-3004. You NC, Chen BH, Song Y, Lu X, Chen Y, Manson JE, Kang M, Howard BV, Margolis KL, Curb JD, Phillips LS, Stefanick ML, Tinker LF, Liu S. PMID: 22829448; PMCID: PMC3478524.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    44. A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation. PLoS Genet. 2012; 8(7):e1002805. Coviello AD, Haring R, Wellons M, Vaidya D, Lehtimäki T, Keildson S, Lunetta KL, He C, Fornage M, Lagou V, Mangino M, Onland-Moret NC, Chen B, Eriksson J, Garcia M, Liu YM, Koster A, Lohman K, Lyytikäinen LP, Petersen AK, Prescott J, Stolk L, Vandenput L, Wood AR, Zhuang WV, Ruokonen A, Hartikainen AL, Pouta A, Bandinelli S, Biffar R, Brabant G, Cox DG, Chen Y, Cummings S, Ferrucci L, Gunter MJ, Hankinson SE, Martikainen H, Hofman A, Homuth G, Illig T, Jansson JO, Johnson AD, Karasik D, Karlsson M, Kettunen J, Kiel DP, Kraft P, Liu J, Ljunggren Ö, Lorentzon M, Maggio M, Markus MR, Mellström D, Miljkovic I, Mirel D, Nelson S, Morin Papunen L, Peeters PH, Prokopenko I, Raffel L, Reincke M, Reiner AP, Rexrode K, Rivadeneira F, Schwartz SM, Siscovick D, Soranzo N, Stöckl D, Tworoger S, Uitterlinden AG, van Gils CH, Vasan RS, Wichmann HE, Zhai G, Bhasin S, Bidlingmaier M, Chanock SJ, De Vivo I, Harris TB, Hunter DJ, Kähönen M, Liu S, Ouyang P, Spector TD, van der Schouw YT, Viikari J, Wallaschofski H, McCarthy MI, Frayling TM, Murray A, Franks S, Järvelin MR, de Jong FH, Raitakari O, Teumer A, Ohlsson C, Murabito JM, Perry JR. PMID: 22829776; PMCID: PMC3400553.
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    45. Coffee and caffeine consumption in relation to sex hormone-binding globulin and risk of type 2 diabetes in postmenopausal women. Diabetes. 2011 Jan; 60(1):269-75. Goto A, Song Y, Chen BH, Manson JE, Buring JE, Liu S. PMID: 21030499; PMCID: PMC3012180.
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    46. Association of resistin promoter polymorphisms with plasma resistin levels and type 2 diabetes in women and men. Int J Mol Epidemiol Genet. 2010; 1(3):167-74. Chen BH, Song Y, Ding EL, Manson JE, Roberts CK, Rifai N, Buring JE, Gaziano JM, Liu S. PMID: 21116434; PMCID: PMC2992359.
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    47. Circulating levels of resistin and risk of type 2 diabetes in men and women: results from two prospective cohorts. Diabetes Care. 2009 Feb; 32(2):329-34. Chen BH, Song Y, Ding EL, Roberts CK, Manson JE, Rifai N, Buring JE, Gaziano JM, Liu S. PMID: 18957529; PMCID: PMC2628703.
      View in: PubMed   Mentions: 46     Fields:    Translation:Humans
    48. NTD prevalences in central California before and after folic acid fortification. Birth Defects Res A Clin Mol Teratol. 2008 Aug; 82(8):547-52. Chen BH, Carmichael SL, Selvin S, Abrams B, Shaw GM. PMID: 18496833.
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    49. Association between 49 infant gene polymorphisms and preterm delivery. Am J Med Genet A. 2007 Sep 01; 143A(17):1990-6. Chen BH, Carmichael SL, Shaw GM, Iovannisci DM, Lammer EJ. PMID: 17676631.
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    50. Novel risk factor in gastroschisis: change of paternity. Am J Med Genet A. 2007 Apr 01; 143A(7):653-9. Chambers CD, Chen BH, Kalla K, Jernigan L, Jones KL, Jones KL. PMID: 17163540.
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    51. Prevalence of periconceptional folic acid use and perceived barriers to the postgestation continuance of supplemental folic acid: survey results from a Teratogen Information Service. Birth Defects Res A Clin Mol Teratol. 2006 Mar; 76(3):193-9. Goldberg BB, Alvarado S, Chavez C, Chen BH, Dick LM, Felix RJ, Kao KK, Chambers CD, Teratogen Information Service. PMID: 16511885.
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