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Brett Meyer

Title(s)Professor Of Clinical, Neurosciences
SchoolHealth Sciences
Phone619-543-6867
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    Collapse Research 
    Collapse Research Activities and Funding
    San Diego StrokeNet Regional Coordinating Center
    NIH/NINDS U24NS107225Aug 15, 2018 - Jul 31, 2023
    Role: Principal Investigator
    UCSD Regional Coordinating Center for the NINDS Stroke Trials Network
    NIH/NINDS U10NS086535Sep 30, 2013 - Jul 31, 2018
    Role: Principal Investigator
    Therapeutic Window for Acute Stroke Therapy (P50)
    NIH/NINDS P50NS044148Jul 1, 2002 - Apr 30, 2014
    Role: Principal Investigator
    General Clinical Research Center
    NIH/NCRR M01RR000827Mar 1, 1974 - Nov 30, 2010
    Role: Co-Investigator

    Collapse ORNG Applications 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. McGehrin K, Spokoyny I, Meyer BC, Agrawal K. The COAST stroke advance directive: A novel approach to preserving patient autonomy. Neurol Clin Pract. 2018 Dec; 8(6):521-526. PMID: 30588382.
      View in: PubMed
    2. Chang VA, Meyer DM, Meyer BC. Isolated Anisocoria as a Presenting Stroke Code Symptom is Unlikely to Result in Alteplase Administration. J Stroke Cerebrovasc Dis. 2019 Jan; 28(1):163-166. PMID: 30322757.
      View in: PubMed
    3. Levine SR, Weingast SZ, Weedon J, Stefanov DG, Katz P, Hurley D, Kasner SE, Khatri P, Broderick JP, Grotta JC, Feldmann E, Panagos PD, Romano JG, Bianchi R, Meyer BC, Scott PA, Kim D, Balucani C. To Treat or Not to Treat? Stroke. 2018 Aug; 49(8):1933-1938. PMID: 29976582.
      View in: PubMed
    4. Attenhofer KS, Hailey L, Mortin M, Rapp KS, Agrawal K, Huisa-Garate B, Modir R, Meyer DM, Hemmen TM, Meyer BC. The Sustained DeyeCOM Sign as a Predictor of Large Vessel Occlusions and Stroke Mimics. J Stroke Cerebrovasc Dis. 2018 Jun; 27(6):1466-1470. PMID: 29398532.
      View in: PubMed
    5. Wolcott Z, Batra A, Bevers MB, Sastre C, Khoury J, Sperling M, Meyer BC, Walsh KB, Adeoye O, Broderick JP, Kimberly WT. Soluble ST2 predicts outcome and hemorrhagic transformation after acute stroke. Ann Clin Transl Neurol. 2017 08; 4(8):553-563. PMID: 28812045.
      View in: PubMed
    6. Nael K, Knitter JR, Jahan R, Gornbein J, Ajani Z, Feng L, Meyer BC, Schwamm LH, Yoo AJ, Marshall RS, Meyers PM, Yavagal DR, Wintermark M, Liebeskind DS, Guzy J, Starkman S, Saver JL, Kidwell CS. Multiparametric Magnetic Resonance Imaging for Prediction of Parenchymal Hemorrhage in Acute Ischemic Stroke After Reperfusion Therapy. Stroke. 2017 03; 48(3):664-670. PMID: 28138001.
      View in: PubMed
    7. Lyden P, Hemmen T, Grotta J, Rapp K, Ernstrom K, Rzesiewicz T, Parker S, Concha M, Hussain S, Agarwal S, Meyer B, Jurf J, Altafullah I, Raman R. Results of the ICTuS 2 Trial (Intravascular Cooling in the Treatment of Stroke 2). Stroke. 2016 12; 47(12):2888-2895. PMID: 27834742.
      View in: PubMed
    8. Agrawal K, Raman R, Ernstrom K, Claycomb RJ, Meyer DM, Hemmen TM, Modir RF, Kachhi P, Meyer BC. Accuracy of Stroke Diagnosis in Telestroke-Guided Tissue Plasminogen Activator Patients. J Stroke Cerebrovasc Dis. 2016 Dec; 25(12):2942-2946. PMID: 27599906.
      View in: PubMed
    9. Spokoyny I, Chen JY, Raman R, Ernstrom K, Agrawal K, Modir RF, Meyer DM, Meyer BC. Visual Determination of Conjugate Eye Deviation on Computed Tomography Scan Predicts Diagnosis of Stroke Code Patients. J Stroke Cerebrovasc Dis. 2016 Dec; 25(12):2809-2813. PMID: 27576212.
      View in: PubMed
    10. Guluma KZ, Liebeskind DS, Raman R, Rapp KS, Ernstrom KB, Alexandrov AV, Shahripour RB, Barlinn K, Starkman S, Grunberg ID, Hemmen TM, Meyer BC, Alexandrov AW. Feasibility and Safety of Using External Counterpulsation to Augment Cerebral Blood Flow in Acute Ischemic Stroke-The Counterpulsation to Upgrade Forward Flow in Stroke (CUFFS) Trial. J Stroke Cerebrovasc Dis. 2015 Nov; 24(11):2596-604. PMID: 26347398; PMCID: PMC4630102 [Available on 11/01/16].
      View in: PubMed, PubMed Central
    11. Spokoyny I, Raman R, Ernstrom K, Kim AJ, Meyer BC, Karanjia NP. Accuracy of First Recorded "Last Known Normal" Times of Stroke Code Patients. J Stroke Cerebrovasc Dis. 2015 Nov; 24(11):2467-73. PMID: 26341734; PMCID: PMC4630074 [Available on 11/01/16].
      View in: PubMed, PubMed Central
    12. Spokoyny I, Raman R, Ernstrom K, Khatri P, Meyer DM, Hemmen TM, Meyer BC. Defining mild stroke: outcomes analysis of treated and untreated mild stroke patients. J Stroke Cerebrovasc Dis. 2015 Jun; 24(6):1276-81. PMID: 25906938; PMCID: PMC4457618.
      View in: PubMed, PubMed Central
    13. Coffman CR, Raman R, Ernstrom K, Herial NA, Schlick KH, Rapp K, Modir RF, Meyer DM, Hemmen TM, Meyer BC. The "DeyeCOM Sign": Predictive Value in Acute Stroke Code Evaluations. J Stroke Cerebrovasc Dis. 2015 Jun; 24(6):1299-304. PMID: 25891758; PMCID: PMC4457625.
      View in: PubMed, PubMed Central
    14. Neil WP, Raman R, Hemmen TM, Ernstrom K, Meyer BC, Meyer DM, Ovbiagele B. Association of Hispanic ethnicity with acute ischemic stroke care processes and outcomes. Ethn Dis. 2015; 25(1):19-23. PMID: 25812247.
      View in: PubMed
    15. Spokoyny I, Cederquist L, Clay B, Meyer BC. COAST (Coordinating Options for Acute Stroke Therapy): An Advance Directive for Stroke. J Clin Ethics. 2015; 26(3):206-11. PMID: 26399670.
      View in: PubMed
    16. De Los Rios F, Kleindorfer DO, Guzik A, Ortega-Gutierrez S, Sangha N, Kumar G, Grotta JC, Lee JM, Meyer BC, Schwamm LH, Khatri P. Intravenous fibrinolysis eligibility: a survey of stroke clinicians' practice patterns and review of the literature. J Stroke Cerebrovasc Dis. 2014 Sep; 23(8):2130-2138. PMID: 25113084; PMCID: PMC4157964.
      View in: PubMed, PubMed Central
    17. Elkind MS, Luna JM, McClure LA, Zhang Y, Coffey CS, Roldan A, Del Brutto OH, Pretell EJ, Pettigrew LC, Meyer BC, Tapia J, White C, Benavente OR. C-reactive protein as a prognostic marker after lacunar stroke: levels of inflammatory markers in the treatment of stroke study. Stroke. 2014 Mar; 45(3):707-16. PMID: 24523037; PMCID: PMC4114338.
      View in: PubMed, PubMed Central
    18. Spokoyny I, Raman R, Ernstrom K, Meyer BC, Hemmen TM. Imaging negative stroke: diagnoses and outcomes in intravenous tissue plasminogen activator-treated patients. J Stroke Cerebrovasc Dis. 2014 May-Jun; 23(5):1046-50. PMID: 24103663; PMCID: PMC3976894.
      View in: PubMed, PubMed Central
    19. Chee B, Raman R, Ernstrom K, Guzik AK, Hemmen TM, Rapp KS, Meyer BC, Meyer DM. Does symptom onset to primary stroke center time goals affect stroke outcome? J Stroke Cerebrovasc Dis. 2014 May-Jun; 23(5):993-1000. PMID: 24103670.
      View in: PubMed
    20. Pancioli AM, Adeoye O, Schmit PA, Khoury J, Levine SR, Tomsick TA, Sucharew H, Brooks CE, Crocco TJ, Gutmann L, Hemmen TM, Kasner SE, Kleindorfer D, Knight WA, Martini S, McKinney JS, Meurer WJ, Meyer BC, Schneider A, Scott PA, Starkman S, Warach S, Broderick JP. Combined approach to lysis utilizing eptifibatide and recombinant tissue plasminogen activator in acute ischemic stroke-enhanced regimen stroke trial. Stroke. 2013 Sep; 44(9):2381-7. PMID: 23887841; PMCID: PMC3970761.
      View in: PubMed, PubMed Central
    21. Levine SR, Khatri P, Broderick JP, Grotta JC, Kasner SE, Kim D, Meyer BC, Panagos P, Romano J, Scott P. Review, historical context, and clarifications of the NINDS rt-PA stroke trials exclusion criteria: Part 1: rapidly improving stroke symptoms. Stroke. 2013 Sep; 44(9):2500-5. PMID: 23847249; PMCID: PMC3789593.
      View in: PubMed, PubMed Central
    22. Spokoyny I, Raman R, Ernstrom K, Demaerschalk BM, Lyden PD, Hemmen TM, Guzik AK, Chen JY, Meyer BC. Pooled assessment of computed tomography interpretation by vascular neurologists in the STRokE DOC telestroke network. J Stroke Cerebrovasc Dis. 2014 Mar; 23(3):511-5. PMID: 23697761; PMCID: PMC3766466.
      View in: PubMed, PubMed Central
    23. Hölscher T, Dunford JV, Schlachetzki F, Boy S, Hemmen T, Meyer BC, Serra J, Powers J, Voie A. Prehospital stroke diagnosis and treatment in ambulances and helicopters-a concept paper. Am J Emerg Med. 2013 Apr; 31(4):743-7. PMID: 23415600.
      View in: PubMed
    24. Kidwell CS, Jahan R, Gornbein J, Alger JR, Nenov V, Ajani Z, Feng L, Meyer BC, Olson S, Schwamm LH, Yoo AJ, Marshall RS, Meyers PM, Yavagal DR, Wintermark M, Guzy J, Starkman S, Saver JL. A trial of imaging selection and endovascular treatment for ischemic stroke. N Engl J Med. 2013 Mar 07; 368(10):914-23. PMID: 23394476; PMCID: PMC3690785.
      View in: PubMed, PubMed Central
    25. Albright KC, Savitz SI, Raman R, Martin-Schild S, Broderick J, Ernstrom K, Ford A, Khatri R, Kleindorfer D, Liebeskind D, Marshall R, Merino JG, Meyer DM, Rost N, Meyer BC. Comprehensive stroke centers and the 'weekend effect': the SPOTRIAS experience. Cerebrovasc Dis. 2012; 34(5-6):424-9. PMID: 23207423; PMCID: PMC3568158.
      View in: PubMed, PubMed Central
    26. Demaerschalk BM, Bobrow BJ, Raman R, Ernstrom K, Hoxworth JM, Patel AC, Kiernan TE, Aguilar MI, Ingall TJ, Dodick DW, Meyer BC. CT interpretation in a telestroke network: agreement among a spoke radiologist, hub vascular neurologist, and hub neuroradiologist. Stroke. 2012 Nov; 43(11):3095-7. PMID: 22984007; PMCID: PMC3502613.
      View in: PubMed, PubMed Central
    27. Huisa BN, Chen Y, Meyer BC, Tafreshi GM, Zivin JA. Incremental treatments with laser therapy augments good behavioral outcome in the rabbit small clot embolic stroke model. Lasers Med Sci. 2013 Jul; 28(4):1085-9. PMID: 22945539; PMCID: PMC3538923.
      View in: PubMed, PubMed Central
    28. Meyer BC, Demaerschalk BM. Telestroke network fundamentals. J Stroke Cerebrovasc Dis. 2012 Oct; 21(7):521-9. PMID: 22885074.
      View in: PubMed
    29. Meyer BC, Clarke CA, Troke TM, Friedman LS. Essential telemedicine elements (tele-ments) for connecting the academic health center and remote community providers to enhance patient care. Acad Med. 2012 Aug; 87(8):1032-40. PMID: 22722348.
      View in: PubMed
    30. Willey JZ, Ortega-Gutierrez S, Petersen N, Khatri P, Ford AL, Rost NS, Ali LK, Gonzales NR, Merino JG, Meyer BC, Marshall RS. Impact of acute ischemic stroke treatment in patients >80 years of age: the specialized program of translational research in acute stroke (SPOTRIAS) consortium experience. Stroke. 2012 Sep; 43(9):2369-75. PMID: 22798327; PMCID: PMC3429792.
      View in: PubMed, PubMed Central
    31. Meyer BC. Telestroke evolution: from maximization to optimization. Stroke. 2012 Aug; 43(8):2029-30. PMID: 22693126; PMCID: PMC3408213.
      View in: PubMed, PubMed Central
    32. White CL, Szychowski JM, Roldan A, Benavente MF, Pretell EJ, Del Brutto OH, Kase CS, Arauz A, Meyer BC, Meissner I, Demaerschalk BM, McClure LA, Coffey CS, Pearce LA, Conwit R, Irby LH, Peri K, Pergola PE, Hart RG, Benavente OR. Clinical features and racial/ethnic differences among the 3020 participants in the Secondary Prevention of Small Subcortical Strokes (SPS3) trial. J Stroke Cerebrovasc Dis. 2013 Aug; 22(6):764-74. PMID: 22516427; PMCID: PMC3970545.
      View in: PubMed, PubMed Central
    33. Demaerschalk BM, Raman R, Ernstrom K, Meyer BC. Efficacy of telemedicine for stroke: pooled analysis of the Stroke Team Remote Evaluation Using a Digital Observation Camera (STRokE DOC) and STRokE DOC Arizona telestroke trials. Telemed J E Health. 2012 Apr; 18(3):230-7. PMID: 22400970; PMCID: PMC3317394.
      View in: PubMed, PubMed Central
    34. Huisa BN, Liebeskind DS, Raman R, Hao Q, Meyer BC, Meyer DM, Hemmen TM. Diffusion-weighted imaging-fluid attenuated inversion recovery mismatch in nocturnal stroke patients with unknown time of onset. J Stroke Cerebrovasc Dis. 2013 Oct; 22(7):972-7. PMID: 22325574; PMCID: PMC3366022.
      View in: PubMed, PubMed Central
    35. Huisa BN, Stemer AB, Walker MG, Rapp K, Meyer BC, Zivin JA. Transcranial laser therapy for acute ischemic stroke: a pooled analysis of NEST-1 and NEST-2. Int J Stroke. 2013 Jul; 8(5):315-20. PMID: 22299818; PMCID: PMC3345315.
      View in: PubMed, PubMed Central
    36. Willey JZ, Khatri P, Khoury JC, Merino JG, Ford AL, Rost NS, Gonzales NR, Ali LK, Meyer BC, Broderick JP. Variability in the use of intravenous thrombolysis for mild stroke: experience across the SPOTRIAS network. J Stroke Cerebrovasc Dis. 2013 May; 22(4):318-22. PMID: 22177935; PMCID: PMC3479337.
      View in: PubMed, PubMed Central
    37. Tafreshi G, Raman R, Ernstrom K, Rapp K, Meyer BC. Late night activity regarding stroke codes: LuNAR strokes. Int J Stroke. 2012 Aug; 7(6):473-6. PMID: 21714850; PMCID: PMC3319328.
      View in: PubMed, PubMed Central
    38. Albright KC, Branas CC, Meyer BC, Matherne-Meyer DE, Zivin JA, Lyden PD, Carr BG. ACCESS: acute cerebrovascular care in emergency stroke systems. Arch Neurol. 2010 Oct; 67(10):1210-8. PMID: 20937948.
      View in: PubMed
    39. Meyer BC, Raman R, Ernstrom K, Tafreshi GM, Huisa B, Stemer AB, Hemmen TM. Assessment of long-term outcomes for the STRokE DOC telemedicine trial. J Stroke Cerebrovasc Dis. 2012 May; 21(4):259-64. PMID: 20851629; PMCID: PMC3017214.
      View in: PubMed, PubMed Central
    40. Hemmen TM, Raman R, Guluma KZ, Meyer BC, Gomes JA, Cruz-Flores S, Wijman CA, Rapp KS, Grotta JC, Lyden PD. Intravenous thrombolysis plus hypothermia for acute treatment of ischemic stroke (ICTuS-L): final results. Stroke. 2010 Oct; 41(10):2265-70. PMID: 20724711; PMCID: PMC2947593.
      View in: PubMed, PubMed Central
    41. Huisa BN, Raman R, Ernstrom K, Tafreshi G, Stemer A, Meyer BC, Hemmen T. Alberta Stroke Program Early CT Score (ASPECTS) in patients with wake-up stroke. J Stroke Cerebrovasc Dis. 2010 Nov-Dec; 19(6):475-9. PMID: 20719536; PMCID: PMC2974782.
      View in: PubMed, PubMed Central
    42. Tafreshi GM, Raman R, Ernstrom K, Meyer BC, Hemmen TM. Gender differences in acute stroke treatment: the University of California San Diego experience. Stroke. 2010 Aug; 41(8):1755-7. PMID: 20538695; PMCID: PMC2910810.
      View in: PubMed, PubMed Central
    43. Demaerschalk BM, Bobrow BJ, Raman R, Kiernan TE, Aguilar MI, Ingall TJ, Dodick DW, Ward MP, Richemont PC, Brazdys K, Koch TC, Miley ML, Hoffman Snyder CR, Corday DA, Meyer BC. Stroke team remote evaluation using a digital observation camera in Arizona: the initial mayo clinic experience trial. Stroke. 2010 Jun; 41(6):1251-8. PMID: 20431081; PMCID: PMC2876204.
      View in: PubMed, PubMed Central
    44. Lyden PD, Meyer BC, Hemmen TM, Rapp KS. An ethical hierarchy for decision making during medical emergencies. Ann Neurol. 2010 Apr; 67(4):434-40. PMID: 20437578; PMCID: PMC2875330.
      View in: PubMed, PubMed Central
    45. Meyer BC, Lyden PD. The modified National Institutes of Health Stroke Scale: its time has come. Int J Stroke. 2009 Aug; 4(4):267-73. PMID: 19689755; PMCID: PMC2729912.
      View in: PubMed, PubMed Central
    46. Schwamm LH, Holloway RG, Amarenco P, Audebert HJ, Bakas T, Chumbler NR, Handschu R, Jauch EC, Knight WA, Levine SR, Mayberg M, Meyer BC, Meyers PM, Skalabrin E, Wechsler LR. A review of the evidence for the use of telemedicine within stroke systems of care: a scientific statement from the American Heart Association/American Stroke Association. Stroke. 2009 Jul; 40(7):2616-34. PMID: 19423852.
      View in: PubMed
    47. Schwamm LH, Audebert HJ, Amarenco P, Chumbler NR, Frankel MR, George MG, Gorelick PB, Horton KB, Kaste M, Lackland DT, Levine SR, Meyer BC, Meyers PM, Patterson V, Stranne SK, White CJ. Recommendations for the implementation of telemedicine within stroke systems of care: a policy statement from the American Heart Association. Stroke. 2009 Jul; 40(7):2635-60. PMID: 19423851.
      View in: PubMed
    48. Albright KC, Raman R, Ernstrom K, Hallevi H, Martin-Schild S, Meyer BC, Meyer DM, Morales MM, Grotta JC, Lyden PD, Savitz SI. Can comprehensive stroke centers erase the 'weekend effect'? Cerebrovasc Dis. 2009; 27(2):107-13. PMID: 19039213; PMCID: PMC2790057.
      View in: PubMed, PubMed Central
    49. Meyer BC, Raman R, Hemmen T, Obler R, Zivin JA, Rao R, Thomas RG, Lyden PD. Efficacy of site-independent telemedicine in the STRokE DOC trial: a randomised, blinded, prospective study. Lancet Neurol. 2008 Sep; 7(9):787-95. PMID: 18676180; PMCID: PMC2744128.
      View in: PubMed, PubMed Central
    50. Meyer BC, Raman R, Chacon MR, Jensen M, Werner JD. Reliability of site-independent telemedicine when assessed by telemedicine-naive stroke practitioners. J Stroke Cerebrovasc Dis. 2008 Jul-Aug; 17(4):181-6. PMID: 18589337.
      View in: PubMed
    51. Guluma KZ, Oh H, Yu SW, Meyer BC, Rapp K, Lyden PD. Effect of endovascular hypothermia on acute ischemic edema: morphometric analysis of the ICTuS trial. Neurocrit Care. 2008; 8(1):42-7. PMID: 17922082.
      View in: PubMed
    52. Hemmen TM, Meyer BC, McClean TL, Lyden PD. Identification of nonischemic stroke mimics among 411 code strokes at the University of California, San Diego, Stroke Center. J Stroke Cerebrovasc Dis. 2008 Jan-Feb; 17(1):23-5. PMID: 18190817.
      View in: PubMed
    53. Meyer BC, Raman R, Rao R, Fellman RD, Beer J, Werner J, Zivin JA, Lyden PD. The STRokE DOC trial technique: 'video clip, drip, and/or ship'. Int J Stroke. 2007 Nov; 2(4):281-7. PMID: 18705930.
      View in: PubMed
    54. Lyden P, Raman R, Liu L, Grotta J, Broderick J, Olson S, Shaw S, Spilker J, Meyer B, Emr M, Warren M, Marler J. NIHSS training and certification using a new digital video disk is reliable. Stroke. 2005 Nov; 36(11):2446-9. PMID: 16224093.
      View in: PubMed
    55. Lyden PD, Allgren RL, Ng K, Akins P, Meyer B, Al-Sanani F, Lutsep H, Dobak J, Matsubara BS, Zivin J. Intravascular Cooling in the Treatment of Stroke (ICTuS): early clinical experience. J Stroke Cerebrovasc Dis. 2005 May-Jun; 14(3):107-14. PMID: 17904009.
      View in: PubMed
    56. Meyer BC, Lyden PD, Al-Khoury L, Cheng Y, Raman R, Fellman R, Beer J, Rao R, Zivin JA. Prospective reliability of the STRokE DOC wireless/site independent telemedicine system. Neurology. 2005 Mar 22; 64(6):1058-60. PMID: 15781827.
      View in: PubMed
    57. Meyer BC, Hemmen TM, Jackson CM, Lyden PD. Modified National Institutes of Health Stroke Scale for use in stroke clinical trials: prospective reliability and validity. Stroke. 2002 May; 33(5):1261-6. PMID: 11988601.
      View in: PubMed
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