Brent Lyda

TitleAssistant Project Scientist
InstitutionUniversity of California San Diego
Address9500 Gilman Drive #0636
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Ye L, Neale C, Sljoka A, Lyda B, Pichugin D, Tsuchimura N, Larda ST, Pomès R, García AE, Ernst OP, Sunahara RK, Prosser RS. Mechanistic insights into allosteric regulation of the A2A adenosine G protein-coupled receptor by physiological cations. Nat Commun. 2018 Apr 10; 9(1):1372. PMID: 29636462.
      View in: PubMed
    2. Korczynska M, Clark MJ, Valant C, Xu J, Moo EV, Albold S, Weiss DR, Torosyan H, Huang W, Kruse AC, Lyda B, May LT, Baltos JA, Sexton PM, Kobilka BK, Christopoulos A, Shoichet BK, Sunahara RK. Structure-based discovery of selective positive allosteric modulators of antagonists for the M2 muscarinic acetylcholine receptor. Proc Natl Acad Sci U S A. 2018 Mar 06; 115(10):E2419-E2428. PMID: 29453275.
      View in: PubMed
    3. Brea RJ, Cole CM, Lyda B, Ye L, Prosser RS, Sunahara RK, Devaraj NK. In Situ Reconstitution of the Adenosine A2A Receptor in Spontaneously Formed Synthetic Liposomes. J Am Chem Soc. 2017 03 15; 139(10):3607-3610. PMID: 28263576.
      View in: PubMed
    4. Chang MR, Lyda B, Kamenecka TM, Griffin PR. Pharmacologic repression of retinoic acid receptor-related orphan nuclear receptor ? is therapeutic in the collagen-induced arthritis experimental model. Arthritis Rheumatol. 2014 Mar; 66(3):579-88. PMID: 24574218; PMCID: PMC4474185.
    5. Kumar N, Lyda B, Chang MR, Lauer JL, Solt LA, Burris TP, Kamenecka TM, Griffin PR. Identification of SR2211: a potent synthetic ROR?-selective modulator. ACS Chem Biol. 2012 Apr 20; 7(4):672-7. PMID: 22292739; PMCID: PMC3331898.
    6. Leary GP, Holley DC, Stone EF, Lyda B, Kalachev LV, Kavanaugh MP. The central cavity in trimeric glutamate transporters restricts ligand diffusion. Proc Natl Acad Sci U S A. 2011 Sep 06; 108(36):14980-5. PMID: 21873219; PMCID: PMC3169134.