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Brandon Aubol

Title(s)Associate Project Scientist, Pharmacology
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Matrix Rigidity Controls Epithelial-Mesenchymal Plasticity and Tumor Metastasis via a Mechanoresponsive EPHA2/LYN Complex. Dev Cell. 2020 Aug 10; 54(3):302-316.e7. Fattet L, Jung HY, Matsumoto MW, Aubol BE, Kumar A, Adams JA, Chen AC, Sah RL, Engler AJ, Pasquale EB, Yang J. PMID: 32574556.
      View in: PubMed   Mentions: 2     Fields:    
    2. A conserved sequence motif bridges two protein kinases for enhanced phosphorylation and nuclear function of a splicing factor. FEBS J. 2020 May 02. Aubol BE, Fattet L, Adams JA. PMID: 32359191.
      View in: PubMed   Mentions: 1     Fields:    
    3. Initiation of Parental Genome Reprogramming in Fertilized Oocyte by Splicing Kinase SRPK1-Catalyzed Protamine Phosphorylation. Cell. 2020 03 19; 180(6):1212-1227.e14. Gou LT, Lim DH, Ma W, Aubol BE, Hao Y, Wang X, Zhao J, Liang Z, Shao C, Zhang X, Meng F, Li H, Zhang X, Xu R, Li D, Rosenfeld MG, Mellon PL, Adams JA, Liu MF, Fu XD. PMID: 32169215.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    4. Disordered protein interactions for an ordered cellular transition: Cdc2-like kinase 1 is transported to the nucleus via its Ser-Arg protein substrate. J Biol Chem. 2019 06 14; 294(24):9631-9641. George A, Aubol BE, Fattet L, Adams JA. PMID: 31064840.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    5. Molecular interactions connecting the function of the serine-arginine-rich protein SRSF1 to protein phosphatase 1. J Biol Chem. 2018 10 26; 293(43):16751-16760. Aubol BE, Serrano P, Fattet L, Wüthrich K, Adams JA. PMID: 30185622.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    6. Mobilization of a splicing factor through a nuclear kinase-kinase complex. Biochem J. 2018 02 14; 475(3):677-690. Aubol BE, Keshwani MM, Fattet L, Adams JA. PMID: 29335301.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    7. Redirecting SR Protein Nuclear Trafficking through an Allosteric Platform. J Mol Biol. 2017 07 07; 429(14):2178-2191. Aubol BE, Hailey KL, Fattet L, Jennings PA, Adams JA. PMID: 28576472.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    8. Release of SR Proteins from CLK1 by SRPK1: A Symbiotic Kinase System for Phosphorylation Control of Pre-mRNA Splicing. Mol Cell. 2016 07 21; 63(2):218-228. Aubol BE, Wu G, Keshwani MM, Movassat M, Fattet L, Hertel KJ, Fu XD, Adams JA. PMID: 27397683.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    9. Directional Phosphorylation and Nuclear Transport of the Splicing Factor SRSF1 Is Regulated by an RNA Recognition Motif. J Mol Biol. 2016 06 05; 428(11):2430-2445. Serrano P, Aubol BE, Keshwani MM, Forli S, Ma CT, Dutta SK, Geralt M, Wüthrich K, Adams JA. PMID: 27091468.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    10. Nuclear protein kinase CLK1 uses a non-traditional docking mechanism to select physiological substrates. Biochem J. 2015 Dec 15; 472(3):329-38. Keshwani MM, Hailey KL, Aubol BE, Fattet L, McGlone ML, Jennings PA, Adams JA. PMID: 26443864.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    11. Intra-domain Cross-talk Regulates Serine-arginine Protein Kinase 1-dependent Phosphorylation and Splicing Function of Transformer 2ß1. J Biol Chem. 2015 Jul 10; 290(28):17269-81. Jamros MA, Aubol BE, Keshwani MM, Zhang Z, Stamm S, Adams JA. PMID: 26013829.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    12. Conserved proline-directed phosphorylation regulates SR protein conformation and splicing function. Biochem J. 2015 Mar 01; 466(2):311-22. Keshwani MM, Aubol BE, Fattet L, Ma CT, Qiu J, Jennings PA, Fu XD, Adams JA. PMID: 25529026.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    13. N-terminus of the protein kinase CLK1 induces SR protein hyperphosphorylation. Biochem J. 2014 Aug 15; 462(1):143-52. Aubol BE, Plocinik RM, Keshwani MM, McGlone ML, Hagopian JC, Ghosh G, Fu XD, Adams JA. PMID: 24869919.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    14. Recruiting a silent partner for activation of the protein kinase SRPK1. Biochemistry. 2014 Jul 22; 53(28):4625-34. Aubol BE, Adams JA. PMID: 24984036.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    15. Splicing kinase SRPK1 conforms to the landscape of its SR protein substrate. Biochemistry. 2013 Oct 29; 52(43):7595-605. Aubol BE, Jamros MA, McGlone ML, Adams JA. PMID: 24074032.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    16. Partitioning RS domain phosphorylation in an SR protein through the CLK and SRPK protein kinases. J Mol Biol. 2013 Aug 23; 425(16):2894-909. Aubol BE, Plocinik RM, Hagopian JC, Ma CT, McGlone ML, Bandyopadhyay R, Fu XD, Adams JA. PMID: 23707382.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    17. Kinetic mechanism of human histidine triad nucleotide binding protein 1. Biochemistry. 2013 May 21; 52(20):3588-600. Zhou X, Chou TF, Aubol BE, Park CJ, Wolfenden R, Adams J, Wagner CR. PMID: 23614568.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    18. Nucleotide release sequences in the protein kinase SRPK1 accelerate substrate phosphorylation. Biochemistry. 2012 Aug 21; 51(33):6584-94. Aubol BE, Plocinik RM, McGlone ML, Adams JA. PMID: 22839969.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    19. C6 pyridinium ceramide influences alternative pre-mRNA splicing by inhibiting protein phosphatase-1. Nucleic Acids Res. 2012 May; 40(9):4025-39. Sumanasekera C, Kelemen O, Beullens M, Aubol BE, Adams JA, Sunkara M, Morris A, Bollen M, Andreadis A, Stamm S. PMID: 22210893.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    20. Applying the brakes to multisite SR protein phosphorylation: substrate-induced effects on the splicing kinase SRPK1. Biochemistry. 2011 Aug 16; 50(32):6888-900. Aubol BE, Adams JA. PMID: 21728354.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    21. SGX523 is an exquisitely selective, ATP-competitive inhibitor of the MET receptor tyrosine kinase with antitumor activity in vivo. . 2009 Dec; 8(12):3181-90. Buchanan SG, Hendle J, Lee PS, Smith CR, Bounaud PY, Jessen KA, Tang CM, Huser NH, Felce JD, Froning KJ, Peterman MC, Aubol BE, Gessert SF, Sauder JM, Schwinn KD, Russell M, Rooney IA, Adams J, Leon BC, Do TH, Blaney JM, Sprengeler PA, Thompson DA, Smyth L, Pelletier LA, Atwell S, Holme K, Wasserman SR, Emtage S, Burley SK, Reich SH. PMID: 19934279.
      View in: PubMed   Mentions:
    22. Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors. Bioorg Med Chem Lett. 2008 May 01; 18(9):2990-5. Antonysamy SS, Aubol B, Blaney J, Browner MF, Giannetti AM, Harris SF, Hébert N, Hendle J, Hopkins S, Jefferson E, Kissinger C, Leveque V, Marciano D, McGee E, Nájera I, Nolan B, Tomimoto M, Torres E, Wright T. PMID: 18400495.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    23. Interplay between SRPK and Clk/Sty kinases in phosphorylation of the splicing factor ASF/SF2 is regulated by a docking motif in ASF/SF2. Mol Cell. 2005 Oct 07; 20(1):77-89. Ngo JC, Chakrabarti S, Ding JH, Velazquez-Dones A, Nolen B, Aubol BE, Adams JA, Fu XD, Ghosh G. PMID: 16209947.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansAnimalsCells
    24. Coupling phosphoryl transfer and substrate interactions in protein kinases. Biochim Biophys Acta. 2005 Dec 30; 1754(1-2):191-9. Lieser SA, Aubol BE, Wong L, Jennings PA, Adams JA. PMID: 16213199.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    25. Phosphoryl transfer step in the C-terminal Src kinase controls Src recognition. J Biol Chem. 2005 Mar 04; 280(9):7769-76. Lieser SA, Shindler C, Aubol BE, Lee S, Sun G, Adams JA. PMID: 15623523.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    26. Dynamic coupling between the SH2 domain and active site of the COOH terminal Src kinase, Csk. J Mol Biol. 2004 Jul 30; 341(1):93-106. Wong L, Lieser S, Chie-Leon B, Miyashita O, Aubol B, Shaffer J, Onuchic JN, Jennings PA, Woods VL, Adams JA. PMID: 15312765.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    27. Chemical clamping allows for efficient phosphorylation of the RNA carrier protein Npl3. J Biol Chem. 2004 Jul 16; 279(29):30182-8. Aubol BE, Ungs L, Lukasiewicz R, Ghosh G, Adams JA. PMID: 15145958.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    28. Novel destabilization of nucleotide binding by the gamma phosphate of ATP in the yeast SR protein kinase Sky1p. Biochemistry. 2003 Nov 11; 42(44):12813-20. Aubol BE, Nolen B, Shaffer J, Ghosh G, Adams JA. PMID: 14596595.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    29. Processive phosphorylation of alternative splicing factor/splicing factor 2. Proc Natl Acad Sci U S A. 2003 Oct 28; 100(22):12601-6. Aubol BE, Chakrabarti S, Ngo J, Shaffer J, Nolen B, Fu XD, Ghosh G, Adams JA. PMID: 14555757.
      View in: PubMed   Mentions: 49     Fields:    Translation:Cells
    30. Murine DNA cytosine C(5)-methyltransferase: in vitro studies of de novo methylation spreading. Biochem Biophys Res Commun. 2003 Oct 10; 310(1):209-14. Aubol BE, Reich NO. PMID: 14511672.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    31. Mechanistic insights into Sky1p, a yeast homologue of the mammalian SR protein kinases. Biochemistry. 2002 Aug 06; 41(31):10002-9. Aubol BE, Nolen B, Vu D, Ghosh G, Adams JA. PMID: 12146964.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
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