Blue Lake

Title(s)Associate Project Scientist, Bioengineering
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
ORCID ORCID Icon0000-0002-8637-9044 Additional info
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    Associate Project Scientist in Bioengineering at the University of California at San Diego (UCSD) working on single-cell genomic studies to map molecular cell diversity of human organs and tissues. Current member of the Human Biomolecular Atlas Program (HuBMAP), Kidney Precision Medicine Project (KPMP) and BRAIN Initiative Cell Census Network (BICCN).

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Scalable dual-omics profiling with single-nucleus chromatin accessibility and mRNA expression sequencing 2 (SNARE-seq2). Nat Protoc. 2021 Oct 14. Plongthongkum N, Diep D, Chen S, Lake BB, Zhang K. PMID: 34650278.
      View in: PubMed   Mentions:    Fields:    
    2. Comparative cellular analysis of motor cortex in human, marmoset and mouse. Nature. 2021 10; 598(7879):111-119. Bakken TE, Jorstad NL, Hu Q, Lake BB, Tian W, Kalmbach BE, Crow M, Hodge RD, Krienen FM, Sorensen SA, Eggermont J, Yao Z, Aevermann BD, Aldridge AI, Bartlett A, Bertagnolli D, Casper T, Castanon RG, Crichton K, Daigle TL, Dalley R, Dee N, Dembrow N, Diep D, Ding SL, Dong W, Fang R, Fischer S, Goldman M, Goldy J, Graybuck LT, Herb BR, Hou X, Kancherla J, Kroll M, Lathia K, van Lew B, Li YE, Liu CS, Liu H, Lucero JD, Mahurkar A, McMillen D, Miller JA, Moussa M, Nery JR, Nicovich PR, Niu SY, Orvis J, Osteen JK, Owen S, Palmer CR, Pham T, Plongthongkum N, Poirion O, Reed NM, Rimorin C, Rivkin A, Romanow WJ, Sedeño-Cortés AE, Siletti K, Somasundaram S, Sulc J, Tieu M, Torkelson A, Tung H, Wang X, Xie F, Yanny AM, Zhang R, Ament SA, Behrens MM, Bravo HC, Chun J, Dobin A, Gillis J, Hertzano R, Hof PR, Höllt T, Horwitz GD, Keene CD, Kharchenko PV, Ko AL, Lelieveldt BP, Luo C, Mukamel EA, Pinto-Duarte A, Preissl S, Regev A, Ren B, Scheuermann RH, Smith K, Spain WJ, White OR, Koch C, Hawrylycz M, Tasic B, Macosko EZ, McCarroll SA, Ting JT, Zeng H, Zhang K, Feng G, Ecker JR, Linnarsson S, Lein ES. PMID: 34616062.
      View in: PubMed   Mentions: 1     Fields:    
    3. A multimodal and integrated approach to interrogate human kidney biopsies with rigor and reproducibility: guidelines from the Kidney Precision Medicine Project. Physiol Genomics. 2021 01 01; 53(1):1-11. El-Achkar TM, Eadon MT, Menon R, Lake BB, Sigdel TK, Alexandrov T, Parikh S, Zhang G, Dobi D, Dunn KW, Otto EA, Anderton CR, Carson JM, Luo J, Park C, Hamidi H, Zhou J, Hoover P, Schroeder A, Joanes M, Azeloglu EU, Sealfon R, Winfree S, Steck B, He Y, D'Agati V, Iyengar R, Troyanskaya OG, Barisoni L, Gaut J, Zhang K, Laszik Z, Rovin BH, Dagher PC, Sharma K, Sarwal MM, Hodgin JB, Alpers CE, Kretzler M, Jain S. PMID: 33197228; PMCID: PMC7847045.
      View in: PubMed   Mentions: 4     Fields:    
    4. The role of the NMD factor UPF3B in olfactory sensory neurons. Elife. 2020 08 10; 9. Tan K, Jones SH, Lake BB, Dumdie JN, Shum EY, Zhang L, Chen S, Sohni A, Pandya S, Gallo RL, Zhang K, Cook-Andersen H, Wilkinson MF. PMID: 32773035; PMCID: PMC7452722.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    5. High-throughput sequencing of the transcriptome and chromatin accessibility in the same cell. Nat Biotechnol. 2019 12; 37(12):1452-1457. Chen S, Lake BB, Zhang K. PMID: 31611697; PMCID: PMC6893138.
      View in: PubMed   Mentions: 72     Fields:    Translation:AnimalsCells
    6. Cellular Recruitment by Podocyte-Derived Pro-migratory Factors in Assembly of the Human Renal Filter. iScience. 2019 Oct 25; 20:402-414. Kim AD, Lake BB, Chen S, Wu Y, Guo J, Parvez RK, Tran T, Thornton ME, Grubbs B, McMahon JA, Zhang K, McMahon AP. PMID: 31622881; PMCID: PMC6817668.
      View in: PubMed   Mentions: 3  
    7. A single-nucleus RNA-sequencing pipeline to decipher the molecular anatomy and pathophysiology of human kidneys. Nat Commun. 2019 06 27; 10(1):2832. Lake BB, Chen S, Hoshi M, Plongthongkum N, Salamon D, Knoten A, Vijayan A, Venkatesh R, Kim EH, Gao D, Gaut J, Zhang K, Jain S. PMID: 31249312; PMCID: PMC6597610.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansCells
    8. Integrative single-cell analysis of transcriptional and epigenetic states in the human adult brain. Nat Biotechnol. 2018 01; 36(1):70-80. Lake BB, Chen S, Sos BC, Fan J, Kaeser GE, Yung YC, Duong TE, Gao D, Chun J, Kharchenko PV, Zhang K. PMID: 29227469; PMCID: PMC5951394.
      View in: PubMed   Mentions: 185     Fields:    Translation:HumansCells
    9. A comparative strategy for single-nucleus and single-cell transcriptomes confirms accuracy in predicted cell-type expression from nuclear RNA. Sci Rep. 2017 07 20; 7(1):6031. Lake BB, Codeluppi S, Yung YC, Gao D, Chun J, Kharchenko PV, Linnarsson S, Zhang K. PMID: 28729663; PMCID: PMC5519641.
      View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
    10. The Homeobox Transcription Factor RHOX10 Drives Mouse Spermatogonial Stem Cell Establishment. Cell Rep. 2016 09 27; 17(1):149-164. Song HW, Bettegowda A, Lake BB, Zhao AH, Skarbrevik D, Babajanian E, Sukhwani M, Shum EY, Phan MH, Plank TM, Richardson ME, Ramaiah M, Sridhar V, de Rooij DG, Orwig KE, Zhang K, Wilkinson MF. PMID: 27681428; PMCID: PMC5063083.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    11. Neuronal subtypes and diversity revealed by single-nucleus RNA sequencing of the human brain. Science. 2016 Jun 24; 352(6293):1586-90. Lake BB, Ai R, Kaeser GE, Salathia NS, Yung YC, Liu R, Wildberg A, Gao D, Fung HL, Chen S, Vijayaraghavan R, Wong J, Chen A, Sheng X, Kaper F, Shen R, Ronaghi M, Fan JB, Wang W, Chun J, Zhang K. PMID: 27339989; PMCID: PMC5038589.
      View in: PubMed   Mentions: 270     Fields:    Translation:HumansCells
    12. Role of Rab11 in planar cell polarity and apical constriction during vertebrate neural tube closure. Nat Commun. 2014 May 13; 5:3734. Ossipova O, Kim K, Lake BB, Itoh K, Ioannou A, Sokol SY. PMID: 24818582; PMCID: PMC4097039.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    13. Genetic approach to track neural cell fate decisions using human embryonic stem cells. Protein Cell. 2014 Jan; 5(1):69-79. Fu X, Rong Z, Zhu S, Wang X, Xu Y, Lake BB. PMID: 24474203; PMCID: PMC3938840.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    14. Rab11 regulates planar polarity and migratory behavior of multiciliated cells in Xenopus embryonic epidermis. Dev Dyn. 2012 Sep; 241(9):1385-95. Kim K, Lake BB, Haremaki T, Weinstein DC, Sokol SY. PMID: 22778024; PMCID: PMC4009926.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    15. Context-dependent enhancement of induced pluripotent stem cell reprogramming by silencing Puma. Stem Cells. 2012 May; 30(5):888-97. Lake BB, Fink J, Klemetsaune L, Fu X, Jeffers JR, Zambetti GP, Xu Y. PMID: 22311782; PMCID: PMC3531606.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    16. Strabismus regulates asymmetric cell divisions and cell fate determination in the mouse brain. J Cell Biol. 2009 Apr 06; 185(1):59-66. Lake BB, Sokol SY. PMID: 19332887; PMCID: PMC2700512.
      View in: PubMed   Mentions: 35     Fields:    Translation:Animals
    17. Requirement of Pygopus 2 in breast cancer. Int J Oncol. 2007 Feb; 30(2):357-63. Andrews PG, Lake BB, Popadiuk C, Kao KR. PMID: 17203217.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    18. Antisense suppression of pygopus2 results in growth arrest of epithelial ovarian cancer. Clin Cancer Res. 2006 Apr 01; 12(7 Pt 1):2216-23. Popadiuk CM, Xiong J, Wells MG, Andrews PG, Dankwa K, Hirasawa K, Lake BB, Kao KR. PMID: 16609037.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    19. Pygopus is required for embryonic brain patterning in Xenopus. Dev Biol. 2003 Sep 01; 261(1):132-48. Lake BB, Kao KR. PMID: 12941625.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    20. Early head specification in Xenopus laevis. ScientificWorldJournal. 2003 Aug 02; 3:655-76. Lake BB, Kao KR. PMID: 12920308; PMCID: PMC5974880.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
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