Bilge Pakiz, EdD is a Project Scientist. Based on her extensive experience in operationalizing community-based research projects, Dr. Pakiz has collaborated with investigators at the Cancer Prevention and Control Program at the UC San Diego Moores Cancer Center and has assisted them with the overall conduct of a number of clinical trials that focus on obesity, behavioral weight loss interventions, and behavioral and metabolic factors associated with disease risk. She is the project director of the UCSD TREC (Transdisciplinary Research on Energetics and Cancer) Center, one of four TREC centers across the US funded by the National Institutes of Health (NIH). The UCSD TREC Center includes four studies that focus on mechanisms linking obesity with breast cancer risk investigate obesity and lifestyle factors related to insulin resistance and inflammation, using mouse models and clinical trials. One of the three TREC clinical trials is the Diet Composition and Genetics: Effects on Weight, Inflammation and Biomarkers study. This project involves a 12-month behavioral weight loss program with 245 obese women assigned to three study arms with different dietary composition. The results will help to refine dietary guidance for optimal weight control and breast cancer prevention and will contribute to knowledge of mechanisms that link insulin resistance, inflammation and obesity to breast cancer risk and progression. Dr. Pakiz also was a Co-Investigator for the Exercise and Nutrition to Enhance Recovery and Good Health for You (ENERGY) study, funded by the National Institutes of Health (NIH). This was a 4-year, multi-site randomized clinical trial of 693 overweight/obese breast cancer survivors, designed to demonstrate the feasibility of achieving sustained weight loss and to examine the impact of weight loss on quality of life and co-morbidities. Other recent studies she has directed include an industry-sponsored trial that tested whether providing portion-controlled prepackaged lunch and dinner entrées in the context of a reduced-energy diet prescription and behavioral counseling promotes greater weight loss in overweight and obese men and women (N=183), compared to control conditions where the prescribed diet is consumed via self-selected foods.