Beverly Emerson

Title(s)Adjunct Professor, Molecular Biology
SchoolAcademic Aff
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    Collapse Research 
    Collapse Research Activities and Funding
    Deregulation of CTCF in Epigenetic Gene Silencing in Human Cancers
    NIH/NCI R01CA159354Jun 1, 2011 - May 31, 2016
    Role: Principal Investigator
    Genomic Mapping of C-G Epigenetic Programs in Hematovascular Progenitor Cells
    NIH/NIGMS R01GM078626Sep 20, 2006 - Aug 31, 2010
    Role: Principal Investigator
    Gordon Conference on the Red Cell
    NIH/NIDDK R13DK059827Jul 15, 2001 - Jun 30, 2002
    Role: Principal Investigator
    NIH/NCI R13CA091512Jan 12, 2001 - Dec 31, 2001
    Role: Principal Investigator
    NIH/NICHD R13HD035945Jul 1, 1997 - Jun 30, 1998
    Role: Principal Investigator
    Specificity of Mammalian SWI/SNF Remodeling Complexes
    NIH/NIGMS R01GM038760Jul 1, 1987 - Nov 30, 2008
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Henderson DJP, Miranda JL, Emerson BM. The ß-NAD+ salvage pathway and PKC-mediated signaling influence localized PARP-1 activity and CTCF Poly(ADP)ribosylation. Oncotarget. 2017 Sep 12; 8(39):64698-64713. PMID: 29029387.
      View in: PubMed
    2. Peña-Hernández R, Marques M, Hilmi K, Zhao T, Saad A, Alaoui-Jamali MA, del Rincon SV, Ashworth T, Roy AL, Emerson BM, Witcher M. Genome-wide targeting of the epigenetic regulatory protein CTCF to gene promoters by the transcription factor TFII-I. Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7):E677-86. PMID: 25646466; PMCID: PMC4343169.
    3. Lee MC, Lopez-Diaz FJ, Khan SY, Tariq MA, Dayn Y, Vaske CJ, Radenbaugh AJ, Kim HJ, Emerson BM, Pourmand N. Single-cell analyses of transcriptional heterogeneity during drug tolerance transition in cancer cells by RNA sequencing. Proc Natl Acad Sci U S A. 2014 Nov 04; 111(44):E4726-35. PMID: 25339441; PMCID: PMC4226127.
    4. Krawczyk M, Emerson BM. p50-associated COX-2 extragenic RNA (PACER) activates COX-2 gene expression by occluding repressive NF-?B complexes. Elife. 2014 Apr 29; 3:e01776. PMID: 24843008; PMCID: PMC4017649.
    5. López-Díaz FJ, Gascard P, Balakrishnan SK, Zhao J, Del Rincon SV, Spruck C, Tlsty TD, Emerson BM. Coordinate transcriptional and translational repression of p53 by TGF-ß1 impairs the stress response. Mol Cell. 2013 May 23; 50(4):552-64. PMID: 23706820; PMCID: PMC3735454.
    6. Balakrishnan SK, Witcher M, Berggren TW, Emerson BM. Functional and molecular characterization of the role of CTCF in human embryonic stem cell biology. PLoS One. 2012; 7(8):e42424. PMID: 22879976; PMCID: PMC3411781.
    7. Lambert G, Estévez-Salmeron L, Oh S, Liao D, Emerson BM, Tlsty TD, Austin RH. An analogy between the evolution of drug resistance in bacterial communities and malignant tissues. Nat Rev Cancer. 2011 05; 11(5):375-82. PMID: 21508974; PMCID: PMC3488437.
    8. Morachis JM, Huang R, Emerson BM. Identification of kinase inhibitors that target transcription initiation by RNA polymerase II. Oncotarget. 2011 Jan-Feb; 2(1-2):18-28. PMID: 21378408; PMCID: PMC3248145.
    9. Morachis JM, Murawsky CM, Emerson BM. Regulation of the p53 transcriptional response by structurally diverse core promoters. Genes Dev. 2010 Jan 15; 24(2):135-47. PMID: 20040571; PMCID: PMC2807349.
    10. Witcher M, Emerson BM. Epigenetic silencing of the p16(INK4a) tumor suppressor is associated with loss of CTCF binding and a chromatin boundary. Mol Cell. 2009 May 15; 34(3):271-84. PMID: 19450526; PMCID: PMC2723750.
    11. Kaeser MD, Aslanian A, Dong MQ, Yates JR, Emerson BM. BRD7, a novel PBAF-specific SWI/SNF subunit, is required for target gene activation and repression in embryonic stem cells. J Biol Chem. 2008 Nov 21; 283(47):32254-63. PMID: 18809673; PMCID: PMC2583284.
    12. Kaeser MD, Emerson BM. Remodeling plans for cellular specialization: unique styles for every room. Curr Opin Genet Dev. 2006 Oct; 16(5):508-12. PMID: 16905306.
      View in: PubMed
    13. Gomes NP, Bjerke G, Llorente B, Szostek SA, Emerson BM, Espinosa JM. Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program. Genes Dev. 2006 Mar 01; 20(5):601-12. PMID: 16510875; PMCID: PMC1410802.
    14. Ling J, Baibakov B, Pi W, Emerson BM, Tuan D. The HS2 enhancer of the beta-globin locus control region initiates synthesis of non-coding, polyadenylated RNAs independent of a cis-linked globin promoter. J Mol Biol. 2005 Jul 29; 350(5):883-96. PMID: 15979088.
      View in: PubMed
    15. Zhang X, Odom DT, Koo SH, Conkright MD, Canettieri G, Best J, Chen H, Jenner R, Herbolsheimer E, Jacobsen E, Kadam S, Ecker JR, Emerson B, Hogenesch JB, Unterman T, Young RA, Montminy M. Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues. Proc Natl Acad Sci U S A. 2005 Mar 22; 102(12):4459-64. PMID: 15753290; PMCID: PMC555478.
    16. Best JL, Amezcua CA, Mayr B, Flechner L, Murawsky CM, Emerson B, Zor T, Gardner KH, Montminy M. Identification of small-molecule antagonists that inhibit an activator: coactivator interaction. Proc Natl Acad Sci U S A. 2004 Dec 21; 101(51):17622-7. PMID: 15585582; PMCID: PMC539725.
    17. Xu W, Cho H, Kadam S, Banayo EM, Anderson S, Yates JR, Emerson BM, Evans RM. A methylation-mediator complex in hormone signaling. Genes Dev. 2004 Jan 15; 18(2):144-56. PMID: 14729568; PMCID: PMC324421.
    18. Espinosa JM, Verdun RE, Emerson BM. p53 functions through stress- and promoter-specific recruitment of transcription initiation components before and after DNA damage. Mol Cell. 2003 Oct; 12(4):1015-27. PMID: 14580351.
      View in: PubMed
    19. Kadam S, Emerson BM. Transcriptional specificity of human SWI/SNF BRG1 and BRM chromatin remodeling complexes. Mol Cell. 2003 Feb; 11(2):377-89. PMID: 12620226.
      View in: PubMed
    20. Kadam S, Emerson BM. Mechanisms of chromatin assembly and transcription. Curr Opin Cell Biol. 2002 Jun; 14(3):262-8. PMID: 12067647.
      View in: PubMed
    21. Emerson BM. Specificity of gene regulation. Cell. 2002 May 03; 109(3):267-70. PMID: 12015975.
      View in: PubMed