Benjamin Yu

TitleAssociate Clinical Professor -
InstitutionUniversity of California San Diego
Address9500 Gilman Drive #0869
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    RAS Signaling in Skin Stem Cell Proliferation and Fate
    NIH/NIAMS R01AR056667Jul 1, 2009 - Apr 30, 2014
    Role: Principal Investigator
    Functional Analysis of Sprouty Genes in Limb Development
    NIH/NICHD K08HD047674Aug 1, 2004 - Jul 31, 2009
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Aoidi R, Houde N, Landry-Truchon K, Holter M, Jacquet K, Charron L, Krishnaswami SR, Yu B, Rauen KA, Bisson N, Newbern J, Charron J. Mek1Y130C mice recapitulate aspects of human cardio-facio-cutaneous syndrome. Dis Model Mech. 2018 Mar 13; 11(3). PMID: 29590634.
      View in: PubMed
    2. Bochner R, Samuelov L, Sarig O, Li Q, Adase CA, Isakov O, Malchin N, Vodo D, Shayevitch R, Peled A, Yu B, Fainberg G, Warshauer E, Adir N, Erez N, Gat A, Gottlieb Y, Rogers T, Pavlovsky M, Goldberg I, Shomron N, Sandilands A, Campbell LE, MacCallum S, McLean WH, Ast G, Gallo RL, Uitto J, Sprecher E. Calpain 12 Function Revealed through the Study of an Atypical Case of Autosomal Recessive Congenital Ichthyosis. J Invest Dermatol. 2017 Feb; 137(2):385-393. PMID: 27769845.
      View in: PubMed
    3. Krishnaswami SR, Kumar S, Ordoukhanian P, Yu B. Fate and plasticity of the epidermis in response to congenital activation of BRAF. J Invest Dermatol. 2015 Feb; 135(2):481-9. PMID: 25202828; PMCID: PMC4289449.
    4. Borkowski AW, Kuo IH, Bernard JJ, Yoshida T, Williams MR, Hung NJ, Yu B, Beck LA, Gallo RL. Toll-like receptor 3 activation is required for normal skin barrier repair following UV damage. J Invest Dermatol. 2015 Feb; 135(2):569-578. PMID: 25118157; PMCID: PMC4289479.
    5. Ouyang H, Xue Y, Lin Y, Zhang X, Xi L, Patel S, Cai H, Luo J, Zhang M, Zhang M, Yang Y, Li G, Li H, Jiang W, Yeh E, Lin J, Pei M, Zhu J, Cao G, Zhang L, Yu B, Chen S, Fu XD, Liu Y, Zhang K. WNT7A and PAX6 define corneal epithelium homeostasis and pathogenesis. Nature. 2014 Jul 17; 511(7509):358-61. PMID: 25030175; PMCID: PMC4610745.
    6. Yoshioka N, Gros E, Li HR, Kumar S, Deacon DC, Maron C, Muotri AR, Chi NC, Fu XD, Yu B, Dowdy SF. Efficient generation of human iPSCs by a synthetic self-replicative RNA. Cell Stem Cell. 2013 Aug 01; 13(2):246-54. PMID: 23910086; PMCID: PMC3845961.
    7. Mukhopadhyay A, Krishnaswami SR, Cowing-Zitron C, Hung NJ, Reilly-Rhoten H, Burns J, Yu B. Negative regulation of Shh levels by Kras and Fgfr2 during hair follicle development. Dev Biol. 2013 Jan 15; 373(2):373-82. PMID: 23123965; PMCID: PMC3536821.
    8. Bernard JJ, Cowing-Zitron C, Nakatsuji T, Muehleisen B, Muto J, Borkowski AW, Martinez L, Greidinger EL, Yu B, Gallo RL. Ultraviolet radiation damages self noncoding RNA and is detected by TLR3. Nat Med. 2012 Aug; 18(8):1286-90. PMID: 22772463; PMCID: PMC3812946.
    9. Hamilton BA, Yu B. Modifier genes and the plasticity of genetic networks in mice. PLoS Genet. 2012; 8(4):e1002644. PMID: 22511884; PMCID: PMC3325199.
    10. Lefkowitz GK, Mukhopadhyay A, Cowing-Zitron C, Yu B. The post-apoptotic fate of RNAs identified through high-throughput sequencing of human hair. PLoS One. 2011; 6(11):e27603. PMID: 22110684; PMCID: PMC3218001.
    11. Du F, Nakamura Y, Tan TL, Lee P, Lee R, Yu B, Jamora C. Expression of snail in epidermal keratinocytes promotes cutaneous inflammation and hyperplasia conducive to tumor formation. Cancer Res. 2010 Dec 15; 70(24):10080-9. PMID: 21159631.
      View in: PubMed
    12. Mukhopadhyay A, Krishnaswami SR, Yu B. Activated Kras alters epidermal homeostasis of mouse skin, resulting in redundant skin and defective hair cycling. J Invest Dermatol. 2011 Feb; 131(2):311-9. PMID: 20944652; PMCID: PMC3335744.
    13. Yu B, Mukhopadhyay A, Wong C. Skin and hair: models for exploring organ regeneration. Hum Mol Genet. 2008 Apr 15; 17(R1):R54-9. PMID: 18632698.
      View in: PubMed
    14. Klein OD, Minowada G, Peterkova R, Kangas A, Yu B, Lesot H, Peterka M, Jernvall J, Martin GR. Sprouty genes control diastema tooth development via bidirectional antagonism of epithelial-mesenchymal FGF signaling. Dev Cell. 2006 Aug; 11(2):181-90. PMID: 16890158; PMCID: PMC2847684.
    15. Yu B, Becker-Hapak M, Snyder EL, Vooijs M, Denicourt C, Dowdy SF. Distinct and nonoverlapping roles for pRB and cyclin D:cyclin-dependent kinases 4/6 activity in melanocyte survival. Proc Natl Acad Sci U S A. 2003 Dec 09; 100(25):14881-6. PMID: 14630948; PMCID: PMC299840.
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