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    Ayse Batova

    TitleProject Scientist
    SchoolUniversity of California, San Diego
    DepartmentPediatrics
    Address200 W. Arbor Drive #8447
    CA San Diego 92103
    Phone619-471-9655
    vCardDownload vCard

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Williams RT, Yu AL, Diccianni MB, Theodorakis EA, Batova A. Erratum: renal cancer-selective Englerin A induces multiple mechanisms of cell death and autophagy. J Exp Clin Cancer Res. 2014; 33(1):95. PMID: 25480670.
        View in: PubMed
      2. Barnhill LM, Williams RT, Cohen O, Kim Y, Batova A, Mielke JA, Messer K, Pu M, Bao L, Yu AL, Diccianni MB. High Expression of CAI2, a 9p21-Embedded Long Noncoding RNA, Contributes to Advanced-Stage Neuroblastoma. Cancer Res. 2014 Jul 15; 74(14):3753-63. PMID: 25028366.
        View in: PubMed
      3. Williams RT, Barnhill LM, Kuo HH, Lin WD, Batova A, Yu AL, Diccianni MB. Chimeras of p14ARF and p16: Functional Hybrids with the Ability to Arrest Growth. PLoS One. 2014; 9(2):e88219. PMID: 24505435.
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      4. Williams RT, Yu AL, Diccianni MB, Theodorakis EA, Batova A. Renal cancer-selective Englerin A induces multiple mechanisms of cell death and autophagy. J Exp Clin Cancer Res. 2013; 32(1):57. PMID: 23958461.
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      5. Elbel KM, Guizzunti G, Theodoraki MA, Xu J, Batova A, Dakanali M, Theodorakis EA. A-ring oxygenation modulates the chemistry and bioactivity of caged Garcinia xanthones. Org Biomol Chem. 2013 May 28; 11(20):3341-8. PMID: 23563530.
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      6. Guizzunti G, Batova A, Chantarasriwong O, Dakanali M, Theodorakis EA. Subcellular localization and activity of gambogic acid. Chembiochem. 2012 May 29; 13(8):1191-8. PMID: 22532297.
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      7. Xu J, Caro-Diaz EJ, Batova A, Sullivan SD, Theodorakis EA. Formal synthesis of (-)-englerin A and cytotoxicity studies of truncated englerins. Chem Asian J. 2012 May; 7(5):1052-60. PMID: 22415793.
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      8. Guizzunti G, Theodorakis EA, Yu AL, Zurzolo C, Batova A. Cluvenone induces apoptosis via a direct target in mitochondria: a possible mechanism to circumvent chemo-resistance? Invest New Drugs. 2012 Oct; 30(5):1841-8. PMID: 21898184.
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      9. Batova A, Altomare D, Chantarasriwong O, Ohlsen KL, Creek KE, Lin YC, Messersmith A, Yu AL, Yu J, Theodorakis EA. The synthetic caged garcinia xanthone cluvenone induces cell stress and apoptosis and has immune modulatory activity. Mol Cancer Ther. 2010 Nov; 9(11):2869-78. PMID: 20881270.
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      10. Chantarasriwong O, Batova A, Chavasiri W, Theodorakis EA. Chemistry and biology of the caged Garcinia xanthones. Chemistry. 2010 Sep 3; 16(33):9944-62. PMID: 20648491.
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      11. Chantarasriwong O, Cho WC, Batova A, Chavasiri W, Moore C, Rheingold AL, Theodorakis EA. Evaluation of the pharmacophoric motif of the caged Garcinia xanthones. Org Biomol Chem. 2009 Dec 7; 7(23):4886-94. PMID: 19907779.
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      12. Batova A, Lam T, Wascholowski V, Yu AL, Giannis A, Theodorakis EA. Synthesis and evaluation of caged Garcinia xanthones. Org Biomol Chem. 2007 Feb 7; 5(3):494-500. PMID: 17252132.
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      13. Batova A, Cottam H, Yu J, Diccianni MB, Carrera CJ, Yu AL. EFA (9-beta-D-erythrofuranosyladenine) is an effective salvage agent for methylthioadenosine phosphorylase-selective therapy of T-cell acute lymphoblastic leukemia with L-alanosine. Blood. 2006 Feb 1; 107(3):898-903. PMID: 16234352.
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      14. Gebauer S, Yu AL, Omura-Minamisawa M, Batova A, Diccianni MB. Expression profiles and clinical relationships of ID2, CDKN1B, and CDKN2A in primary neuroblastoma. Genes Chromosomes Cancer. 2004 Dec; 41(4):297-308. PMID: 15390183.
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      15. Batova A, Shao LE, Diccianni MB, Yu AL, Tanaka T, Rephaeli A, Nudelman A, Yu J. The histone deacetylase inhibitor AN-9 has selective toxicity to acute leukemia and drug-resistant primary leukemia and cancer cell lines. Blood. 2002 Nov 1; 100(9):3319-24. PMID: 12384433.
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      16. Omura-Minamisawa M, Diccianni MB, Chang RC, Batova A, Bridgeman LJ, Schiff J, Cohn SL, London WB, Yu AL. p16/p14(ARF) cell cycle regulatory pathways in primary neuroblastoma: p16 expression is associated with advanced stage disease. Clin Cancer Res. 2001 Nov; 7(11):3481-90. PMID: 11705866.
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      17. Omura-Minamisawa M, Diccianni MB, Batova A, Chang RC, Bridgeman LJ, Yu J, de Wit E, Kung FH, Pullen JD, Yu AL. In vitro sensitivity of T-cell lymphoblastic leukemia to UCN-01 (7-hydroxystaurosporine) is dependent on p16 protein status: a Pediatric Oncology Group study. Cancer Res. 2000 Dec 1; 60(23):6573-6. PMID: 11118035.
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      18. Borger DR, Mi Y, Geslani G, Zyzak LL, Batova A, Engin TS, Pirisi L, Creek KE. Retinoic acid resistance at late stages of human papillomavirus type 16-mediated transformation of human keratinocytes arises despite intact retinoid signaling and is due to a loss of sensitivity to transforming growth factor-beta. Virology. 2000 May 10; 270(2):397-407. PMID: 10792999.
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      19. Omura-Minamisawa M, Diccianni MB, Batova A, Chang RC, Bridgeman LJ, Yu J, Pullen J, Bowman WP, Yu AL. Universal inactivation of both p16 and p15 but not downstream components is an essential event in the pathogenesis of T-cell acute lymphoblastic leukemia. Clin Cancer Res. 2000 Apr; 6(4):1219-28. PMID: 10778944.
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      20. Batova A, Kamps A, Gillies SD, Reisfeld RA, Yu AL. The Ch14.18-GM-CSF fusion protein is effective at mediating antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity in vitro. Clin Cancer Res. 1999 Dec; 5(12):4259-63. PMID: 10632368.
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      21. Batova A, Diccianni MB, Omura-Minamisawa M, Yu J, Carrera CJ, Bridgeman LJ, Kung FH, Pullen J, Amylon MD, Yu AL. Use of alanosine as a methylthioadenosine phosphorylase-selective therapy for T-cell acute lymphoblastic leukemia in vitro. Cancer Res. 1999 Apr 1; 59(7):1492-7. PMID: 10197619.
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      22. Wong YF, Chung TK, Cheung TH, Nobori T, Yu AL, Yu J, Batova A, Lai KW, Chang AM. Methylation of p16INK4A in primary gynecologic malignancy. Cancer Lett. 1999 Mar 1; 136(2):231-5. PMID: 10355753.
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      23. Diccianni MB, Omura-Minamisawa M, Batova A, Le T, Bridgeman L, Yu AL. Frequent deregulation of p16 and the p16/G1 cell cycle-regulatory pathway in neuroblastoma. Int J Cancer. 1999 Jan 5; 80(1):145-54. PMID: 9935245.
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      24. Diccianni MB, Batova A, Yu J, Vu T, Pullen J, Amylon M, Pollock BH, Yu AL. Shortened survival after relapse in T-cell acute lymphoblastic leukemia patients with p16/p15 deletions. Leuk Res. 1997 Jun; 21(6):549-58. PMID: 9279366.
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      25. Yu J, Batova A, Shao L, Carrera CJ, Yu AL. Presence of methylthioadenosine phosphorylase (MTAP) in hematopoietic stem/progenitor cells: its therapeutic implication for MTAP (-) malignancies. Clin Cancer Res. 1997 Mar; 3(3):433-8. PMID: 9815702.
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      26. Batova A, Diccianni MB, Yu JC, Nobori T, Link MP, Pullen J, Yu AL. Frequent and selective methylation of p15 and deletion of both p15 and p16 in T-cell acute lymphoblastic leukemia. Cancer Res. 1997 Mar 1; 57(5):832-6. PMID: 9041181.
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      27. Batova A, Diccianni MB, Nobori T, Vu T, Yu J, Bridgeman L, Yu AL. Frequent deletion in the methylthioadenosine phosphorylase gene in T-cell acute lymphoblastic leukemia: strategies for enzyme-targeted therapy. Blood. 1996 Oct 15; 88(8):3083-90. PMID: 8874207.
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      28. Diccianni MB, Chau LS, Batova A, Vu TQ, Yu AL. The p16 and p18 tumor suppressor genes in neuroblastoma: implications for drug resistance. Cancer Lett. 1996 Jul 12; 104(2):183-92. PMID: 8665486.
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      29. Nobori T, Takabayashi K, Tran P, Orvis L, Batova A, Yu AL, Carson DA. Genomic cloning of methylthioadenosine phosphorylase: a purine metabolic enzyme deficient in multiple different cancers. Proc Natl Acad Sci U S A. 1996 Jun 11; 93(12):6203-8. PMID: 8650244.
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      30. Creek KE, Geslani G, Batova A, Pirisi L. Progressive loss of sensitivity to growth control by retinoic acid and transforming growth factor-beta at late stages of human papillomavirus type 16-initiated transformation of human keratinocytes. Adv Exp Med Biol. 1995; 375:117-35. PMID: 7645423.
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      31. Zyzak LL, MacDonald LM, Batova A, Forand R, Creek KE, Pirisi L. Increased levels and constitutive tyrosine phosphorylation of the epidermal growth factor receptor contribute to autonomous growth of human papillomavirus type 16 immortalized human keratinocytes. Cell Growth Differ. 1994 May; 5(5):537-47. PMID: 8049160.
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      32. Creek KE, Jenkins GR, Khan MA, Batova A, Hodam JR, Tolleson WH, Pirisi L. Retinoic acid suppresses human papillomavirus type 16 (HPV16)-mediated transformation of human keratinocytes and inhibits the expression of the HPV16 oncogenes. Adv Exp Med Biol. 1994; 354:19-35. PMID: 8067286.
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      33. Batova A, Danielpour D, Pirisi L, Creek KE. Retinoic acid induces secretion of latent transforming growth factor beta 1 and beta 2 in normal and human papillomavirus type 16-immortalized human keratinocytes. Cell Growth Differ. 1992 Nov; 3(11):763-72. PMID: 1334692.
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      34. Morré DJ, Morré DM, Paulik M, Batova A, Broome AM, Pirisi L, Creek KE. Retinoic acid and calcitriol inhibition of growth and NADH oxidase of normal and immortalized human keratinocytes. Biochim Biophys Acta. 1992 Apr 7; 1134(3):217-22. PMID: 1558845.
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      35. Pirisi L, Batova A, Jenkins GR, Hodam JR, Creek KE. Increased sensitivity of human keratinocytes immortalized by human papillomavirus type 16 DNA to growth control by retinoids. Cancer Res. 1992 Jan 1; 52(1):187-93. PMID: 1370074.
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