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Ayelet Gonen

Title(s)ASSOC PROJ SCI-FY NON REP, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #0682
La Jolla CA 92093
Phone8/5-34--4407
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Generation and characterization of LPA-KIV9, a murine monoclonal antibody binding a single site on apolipoprotein (a). J Lipid Res. 2020 Sep; 61(9):1263-1270. Gonen A, Yang X, Yeang C, Alekseeva E, Koschinsky M, Witztum JL, Boffa M, Tsimikas S. PMID: 32641432.
      View in: PubMed   Mentions:    Fields:    
    2. CD1d Selectively Down Regulates the Expression of the Oxidized Phospholipid-Specific E06 IgM Natural Antibody in Ldlr-/- Mice. Antibodies (Basel). 2020 Jul 03; 9(3). Biswas TK, VanderLaan PA, Que X, Gonen A, Krishack P, Binder CJ, Witztum JL, Getz GS, Reardon CA. PMID: 32635160.
      View in: PubMed   Mentions:
    3. Erratum: A monoclonal antibody to assess oxidized cholesteryl esters associated with apoAI and apoB-100 lipoproteins in human plasma. J Lipid Res. 2019 Nov; 60(11):1979. Gonen A, Choi SH, Miu P, Agatisa-Boyle C, Acks D, Taylor AM, McNamara CA, Tsimikas S, Witztum JL, Miller YI. PMID: 31676683.
      View in: PubMed   Mentions:    Fields:    
    4. Diversification and CXCR4-Dependent Establishment of the Bone Marrow B-1a Cell Pool Governs Atheroprotective IgM Production Linked to Human Coronary Atherosclerosis. Circ Res. 2019 10 25; 125(10):e55-e70. Upadhye A, Srikakulapu P, Gonen A, Hendrikx S, Perry HM, Nguyen A, McSkimming C, Marshall MA, Garmey JC, Taylor AM, Bender TP, Tsimikas S, Holodick NE, Rothstein TL, Witztum JL, McNamara CA. PMID: 31549940.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    5. A monoclonal antibody to assess oxidized cholesteryl esters associated with apoAI and apoB-100 lipoproteins in human plasma. J Lipid Res. 2019 02; 60(2):436-445. Gonen A, Choi SH, Miu P, Agatisa-Boyle C, Acks D, Taylor AM, McNamara CA, Tsimikas S, Witztum JL, Miller YI. PMID: 30563909.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    6. Publisher Correction: Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice. Nature. 2018 09; 561(7724):E43. Que X, Hung MY, Yeang C, Gonen A, Prohaska TA, Sun X, Diehl C, Määttä A, Gaddis DE, Bowden K, Pattison J, MacDonald JG, Ylä-Herttuala S, Mellon PL, Hedrick CC, Ley K, Miller YI, Glass CK, Peterson KL, Binder CJ, Tsimikas S, Witztum JL. PMID: 30013121.
      View in: PubMed   Mentions: 1     Fields:    
    7. Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice. Nature. 2018 06; 558(7709):301-306. Que X, Hung MY, Yeang C, Gonen A, Prohaska TA, Sun X, Diehl C, Määttä A, Gaddis DE, Bowden K, Pattison J, MacDonald JG, Ylä-Herttuala S, Mellon PL, Hedrick CC, Ley K, Miller YI, Glass CK, Peterson KL, Binder CJ, Tsimikas S, Witztum JL. PMID: 29875409.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    8. ABCG1 regulates pulmonary surfactant metabolism in mice and men. J Lipid Res. 2017 05; 58(5):941-954. de Aguiar Vallim TQ, Lee E, Merriott DJ, Goulbourne CN, Cheng J, Cheng A, Gonen A, Allen RM, Palladino END, Ford DA, Wang T, Baldán Á, Tarling EJ. PMID: 28264879.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    9. Protective Role for B-1b B Cells and IgM in Obesity-Associated Inflammation, Glucose Intolerance, and Insulin Resistance. Arterioscler Thromb Vasc Biol. 2016 Apr; 36(4):682-91. Harmon DB, Srikakulapu P, Kaplan JL, Oldham SN, McSkimming C, Garmey JC, Perry HM, Kirby JL, Prohaska TA, Gonen A, Hallowell P, Schirmer B, Tsimikas S, Taylor AM, Witztum JL, McNamara CA. PMID: 26868208.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    10. Blockade of Tim-1 and Tim-4 Enhances Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice. Arterioscler Thromb Vasc Biol. 2016 Mar; 36(3):456-65. Foks AC, Engelbertsen D, Kuperwaser F, Alberts-Grill N, Gonen A, Witztum JL, Lederer J, Jarolim P, DeKruyff RH, Freeman GJ, Lichtman AH. PMID: 26821944.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    11. MD-2 binds cholesterol. Biochem Biophys Res Commun. 2016 Feb 19; 470(4):877-80. Choi SH, Kim J, Gonen A, Viriyakosol S, Miller YI. PMID: 26806306.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    12. B-1b Cells Secrete Atheroprotective IgM and Attenuate Atherosclerosis. Circ Res. 2015 Jul 17; 117(3):e28-39. Rosenfeld SM, Perry HM, Gonen A, Prohaska TA, Srikakulapu P, Grewal S, Das D, McSkimming C, Taylor AM, Tsimikas S, Bender TP, Witztum JL, McNamara CA. PMID: 26082558.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    13. SYK regulates macrophage MHC-II expression via activation of autophagy in response to oxidized LDL. Autophagy. 2015; 11(5):785-95. Choi SH, Gonen A, Diehl CJ, Kim J, Almazan F, Witztum JL, Miller YI. PMID: 25946330.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    14. ABCG1 is required for pulmonary B-1 B cell and natural antibody homeostasis. J Immunol. 2014 Dec 01; 193(11):5637-48. Baldan A, Gonen A, Choung C, Que X, Marquart TJ, Hernandez I, Bjorkhem I, Ford DA, Witztum JL, Tarling EJ. PMID: 25339664.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    15. Atheroprotective immunization with malondialdehyde-modified LDL is hapten specific and dependent on advanced MDA adducts: implications for development of an atheroprotective vaccine. J Lipid Res. 2014 Oct; 55(10):2137-55. Gonen A, Hansen LF, Turner WW, Montano EN, Que X, Rafia A, Chou MY, Wiesner P, Tsiantoulas D, Corr M, VanNieuwenhze MS, Tsimikas S, Binder CJ, Witztum JL, Hartvigsen K. PMID: 25143462.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    16. Interleukin-3/granulocyte macrophage colony-stimulating factor receptor promotes stem cell expansion, monocytosis, and atheroma macrophage burden in mice with hematopoietic ApoE deficiency. Arterioscler Thromb Vasc Biol. 2014 May; 34(5):976-84. Wang M, Subramanian M, Abramowicz S, Murphy AJ, Gonen A, Witztum J, Welch C, Tabas I, Westerterp M, Tall AR. PMID: 24651678.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    17. Innate response activator B cells aggravate atherosclerosis by stimulating T helper-1 adaptive immunity. Circulation. 2014 Apr 22; 129(16):1677-87. Hilgendorf I, Theurl I, Gerhardt LM, Robbins CS, Weber GF, Gonen A, Iwamoto Y, Degousee N, Holderried TA, Winter C, Zirlik A, Lin HY, Sukhova GK, Butany J, Rubin BB, Witztum JL, Libby P, Nahrendorf M, Weissleder R, Swirski FK. PMID: 24488984.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    18. Atheroprotective Vaccination with MHC-II Restricted Peptides from ApoB-100. Front Immunol. 2013; 4:493. Tse K, Gonen A, Sidney J, Ouyang H, Witztum JL, Sette A, Tse H, Ley K. PMID: 24416033.
      View in: PubMed   Mentions: 19     Fields:    
    19. Helix-loop-helix factor inhibitor of differentiation 3 regulates interleukin-5 expression and B-1a B cell proliferation. Arterioscler Thromb Vasc Biol. 2013 Dec; 33(12):2771-9. Perry HM, Oldham SN, Fahl SP, Que X, Gonen A, Harmon DB, Tsimikas S, Witztum JL, Bender TP, McNamara CA. PMID: 24115031.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    20. Peptide mimotopes of malondialdehyde epitopes for clinical applications in cardiovascular disease. J Lipid Res. 2012 Jul; 53(7):1316-26. Amir S, Hartvigsen K, Gonen A, Leibundgut G, Que X, Jensen-Jarolim E, Wagner O, Tsimikas S, Witztum JL, Binder CJ. PMID: 22508944.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimals
    21. Oxidation-specific epitopes are danger-associated molecular patterns recognized by pattern recognition receptors of innate immunity. Circ Res. 2011 Jan 21; 108(2):235-48. Miller YI, Choi SH, Wiesner P, Fang L, Harkewicz R, Hartvigsen K, Boullier A, Gonen A, Diehl CJ, Que X, Montano E, Shaw PX, Tsimikas S, Binder CJ, Witztum JL. PMID: 21252151.
      View in: PubMed   Mentions: 200     Fields:    Translation:HumansAnimalsCells
    22. Fatty acid bile acid conjugate inhibits hepatic stearoyl coenzyme A desaturase and is non-atherogenic. Arch Med Res. 2010 Aug; 41(6):397-404. Leikin-Frenkel A, Gonen A, Shaish A, Goldiner I, Leikin-Gobbi D, Konikoff FM, Harats D, Gilat T. PMID: 21044742.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    23. Low doses of lipopolysaccharide and minimally oxidized low-density lipoprotein cooperatively activate macrophages via nuclear factor kappa B and activator protein-1: possible mechanism for acceleration of atherosclerosis by subclinical endotoxemia. Circ Res. 2010 Jul 09; 107(1):56-65. Wiesner P, Choi SH, Almazan F, Benner C, Huang W, Diehl CJ, Gonen A, Butler S, Witztum JL, Glass CK, Miller YI. PMID: 20489162.
      View in: PubMed   Mentions: 72     Fields:    Translation:AnimalsCells
    24. A 9-cis beta-carotene-enriched diet inhibits atherogenesis and fatty liver formation in LDL receptor knockout mice. J Nutr. 2008 Oct; 138(10):1923-30. Harari A, Harats D, Marko D, Cohen H, Barshack I, Kamari Y, Gonen A, Gerber Y, Ben-Amotz A, Shaish A. PMID: 18806102.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    25. Differential role and tissue specificity of interleukin-1alpha gene expression in atherogenesis and lipid metabolism. Atherosclerosis. 2007 Nov; 195(1):31-8. Kamari Y, Werman-Venkert R, Shaish A, Werman A, Harari A, Gonen A, Voronov E, Grosskopf I, Sharabi Y, Grossman E, Iwakura Y, Dinarello CA, Apte RN, Harats D. PMID: 17173923.
      View in: PubMed   Mentions: 36     Fields:    Translation:Animals
    26. Inhibition of carcinogenesis in transgenic mouse models over-expressing 15-lipoxygenase in the vascular wall under the control of murine preproendothelin-1 promoter. Cancer Lett. 2005 Nov 08; 229(1):127-34. Harats D, Ben-Shushan D, Cohen H, Gonen A, Barshack I, Goldberg I, Greenberger S, Hodish I, Harari A, Varda-Bloom N, Levanon K, Grossman E, Chaitidis P, Kühn H, Shaish A. PMID: 16157225.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    27. The antiatherogenic effect of allicin: possible mode of action. Pathobiology. 2005; 72(6):325-34. Gonen A, Harats D, Rabinkov A, Miron T, Mirelman D, Wilchek M, Weiner L, Ulman E, Levkovitz H, Ben-Shushan D, Shaish A. PMID: 16582584.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
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