Ayako Makino

Title(s)Associate Professor In Residence, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
vCardDownload vCard

    Collapse Research 
    Collapse Research Activities and Funding
    Coronary Microvascular Disease in Diabetes: Role of NAMPT
    DOD W81XWH2110472Jul 1, 2021 - Jun 30, 2025
    Role: Principal Investigator
    Endothelium-driven signaling network in the development of pulmonary hypertension
    NIH R01HL154754Sep 1, 2020 - Jun 30, 2024
    Role: Co-Principal Investigator
    Role of Gap Junction in Hypoxia-induced Pulmonary Hypertension
    NIH R01HL146764May 1, 2019 - Apr 30, 2023
    Role: Principal Investigator
    Coronary Endothelial Cell Dysfunction in Diabetes: Role of HuR
    NIH R01HL142214Mar 1, 2018 - Jan 31, 2022
    Role: Principal Investigator
    Ion Channels and Membrane Receptors in Pulmonary Arterial Hypertension
    NIH R35HL135807Jan 15, 2017 - Dec 31, 2023
    Role: Co-Investigator
    Cellular and Molecular Mechanisms of Coronary Endothelial Dysfunction in Diabetes
    NIH R01HL115578Jul 3, 2012 - Jun 30, 2017
    Role: Principal Investigator
    Mechanisms of coronary endothelial dysfunction in diabetes
    NIH K01DK083506Apr 1, 2009 - Mar 31, 2012
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Mouse model of experimental pulmonary hypertension: Lung angiogram and right heart catheterization. Pulm Circ. 2021 Oct-Dec; 11(4):20458940211041512. Xiong M, Jain PP, Chen J, Babicheva A, Zhao T, Alotaibi M, Kim NH, Lai N, Izadi A, Rodriguez M, Li J, Balistrieri A, Balistrieri F, Parmisano S, Sun X, Voldez-Jasso D, Shyy JY, Thistlethwaite PA, Wang J, Makino A, Yuan JX. PMID: 34531976.
      View in: PubMed   Mentions:
    2. Halofuginone, a promising drug for treatment of pulmonary hypertension. Br J Pharmacol. 2021 09; 178(17):3373-3394. Jain PP, Zhao T, Xiong M, Song S, Lai N, Zheng Q, Chen J, Carr SG, Babicheva A, Izadi A, Rodriguez M, Rahimi S, Balistrieri F, Rahimi S, Simonson T, Valdez-Jasso D, Thistlethwaite PA, Shyy JY, Wang J, Makino A, Yuan JX. PMID: 33694155.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    3. Efferocytosis of vascular cells in cardiovascular disease. Pharmacol Ther. 2021 Jun 23; 107919. Cabrera JTO, Makino A. PMID: 34171333.
      View in: PubMed   Mentions:    Fields:    
    4. mTOR Signaling in Pulmonary Vascular Disease: Pathogenic Role and Therapeutic Target. Int J Mol Sci. 2021 Feb 21; 22(4). Babicheva A, Makino A, Yuan JX. PMID: 33670032.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    5. Chronic Hypoxia Decreases Endothelial Connexin 40, Attenuates Endothelium-Dependent Hyperpolarization-Mediated Relaxation in Small Distal Pulmonary Arteries, and Leads to Pulmonary Hypertension. J Am Heart Assoc. 2020 12 15; 9(24):e018327. Si R, Zhang Q, Cabrera JTO, Zheng Q, Tsuji-Hosokawa A, Watanabe M, Hosokawa S, Xiong M, Jain PP, Ashton AW, Yuan JX, Wang J, Makino A. PMID: 33307937.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    6. Transcriptomic profiles in pulmonary arterial hypertension associate with disease severity and identify novel candidate genes. Pulm Circ. 2020 Oct-Dec; 10(4):2045894020968531. Romanoski CE, Qi X, Sangam S, Vanderpool RR, Stearman RS, Conklin A, Gonzalez-Garay M, Rischard F, Ayon RJ, Wang J, Simonson T, Babicheva A, Shi Y, Tang H, Makino A, Kanthi Y, Geraci MW, Garcia JGN, Yuan JX, Desai AA. PMID: 33343881.
      View in: PubMed   Mentions:
    7. Revisiting the mechanism of hypoxic pulmonary vasoconstriction using isolated perfused/ventilated mouse lung. Pulm Circ. 2020 Oct-Dec; 10(4):2045894020956592. Jain PP, Hosokawa S, Xiong M, Babicheva A, Zhao T, Rodriguez M, Rahimi S, Pourhashemi K, Balistrieri F, Lai N, Malhotra A, Shyy JY, Valdez-Jasso D, Thistlethwaite PA, Makino A, Yuan JX. PMID: 33282184.
      View in: PubMed   Mentions:
    8. Altered Airway Microbiota Composition in Patients With Pulmonary Hypertension. Hypertension. 2020 11; 76(5):1589-1599. Zhang C, Zhang T, Lu W, Duan X, Luo X, Liu S, Chen Y, Li Y, Chen J, Liao J, Zhou D, Chen X, Feng H, Gu G, Wang T, Tang H, Makino A, Zhong N, Yuan JX, Yang K, Wang J. PMID: 32921193.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    9. Endothelial platelet-derived growth factor-mediated activation of smooth muscle platelet-derived growth factor receptors in pulmonary arterial hypertension. Pulm Circ. 2020 Jul-Sep; 10(3):2045894020948470. Wu K, Tang H, Lin R, Carr SG, Wang Z, Babicheva A, Ayon RJ, Jain PP, Xiong M, Rodriguez M, Rahimi S, Balistrieri F, Rahimi S, Valdez-Jasso D, Simonson TS, Desai AA, Garcia JGN, Shyy JY, Thistlethwaite PA, Wang J, Makino A, Yuan JX. PMID: 33294172.
      View in: PubMed   Mentions:
    10. Pulmonary vessel casting in a rat model of monocrotaline-mediated pulmonary hypertension. Pulm Circ. 2020 Jul-Sep; 10(3):2045894020922129. Zhu Z, Wang Y, Long A, Feng T, Ocampo M, Chen S, Tang H, Guo Q, Minshall R, Makino A, Huang W, Chen J. PMID: 32922742.
      View in: PubMed   Mentions:
    11. Overexpression of p53 due to excess protein O-GlcNAcylation is associated with coronary microvascular disease in type 2 diabetes. Cardiovasc Res. 2020 05 01; 116(6):1186-1198. Si R, Zhang Q, Tsuji-Hosokawa A, Watanabe M, Willson C, Lai N, Wang J, Dai A, Scott BT, Dillmann WH, Yuan JX, Makino A. PMID: 31504245.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    12. Tetramethylpyrazine: A promising drug for the treatment of pulmonary hypertension. Br J Pharmacol. 2020 06; 177(12):2743-2764. Chen Y, Lu W, Yang K, Duan X, Li M, Chen X, Zhang J, Kuang M, Liu S, Wu X, Zou G, Liu C, Hong C, He W, Liao J, Hou C, Zhang Z, Zheng Q, Chen J, Zhang N, Tang H, Vanderpool RR, Desai AA, Rischard F, Black SM, Garcia JGN, Makino A, Yuan JX, Zhong N, Wang J. PMID: 31976548.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    13. Notch enhances Ca2+ entry by activating calcium-sensing receptors and inhibiting voltage-gated K+ channels. Am J Physiol Cell Physiol. 2020 05 01; 318(5):C954-C968. Song S, Babicheva A, Zhao T, Ayon RJ, Rodriguez M, Rahimi S, Balistrieri F, Harrington A, Shyy JY, Thistlethwaite PA, Makino A, Yuan JX. PMID: 32186932.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    14. Chloroquine differentially modulates coronary vasodilation in control and diabetic mice. Br J Pharmacol. 2020 01; 177(2):314-327. Zhang Q, Tsuji-Hosokawa A, Willson C, Watanabe M, Si R, Lai N, Wang Z, Yuan JX, Wang J, Makino A. PMID: 31503328.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    15. MicroRNA-mediated downregulation of K+ channels in pulmonary arterial hypertension. Am J Physiol Lung Cell Mol Physiol. 2020 01 01; 318(1):L10-L26. Babicheva A, Ayon RJ, Zhao T, Ek Vitorin JF, Pohl NM, Yamamura A, Yamamura H, Quinton BA, Ba M, Wu L, Ravellette KS, Rahimi S, Balistrieri F, Harrington A, Vanderpool RR, Thistlethwaite PA, Makino A, Yuan JX. PMID: 31553627.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    16. Aortic pathology from protein kinase G activation is prevented by an antioxidant vitamin B12 analog. Nat Commun. 2019 08 06; 10(1):3533. Schwaerzer GK, Kalyanaraman H, Casteel DE, Dalton ND, Gu Y, Lee S, Zhuang S, Wahwah N, Schilling JM, Patel HH, Zhang Q, Makino A, Milewicz DM, Peterson KL, Boss GR, Pilz RB. PMID: 31387997.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    17. Pathogenic Role of mTORC1 and mTORC2 in Pulmonary Hypertension. JACC Basic Transl Sci. 2018 Dec; 3(6):744-762. Tang H, Wu K, Wang J, Vinjamuri S, Gu Y, Song S, Wang Z, Zhang Q, Balistrieri A, Ayon RJ, Rischard F, Vanderpool R, Chen J, Zhou G, Desai AA, Black SM, Garcia JGN, Yuan JX, Makino A. PMID: 30623134.
      View in: PubMed   Mentions:
    18. Divergent changes of p53 in pulmonary arterial endothelial and smooth muscle cells involved in the development of pulmonary hypertension. . 2019 01 01; 316(1):L216-L228. Wang Z, Yang K, Zheng Q, Zhang C, Tang H, Babicheva A, Jiang Q, Li M, Chen Y, Carr SG, Wu K, Zhang Q, Balistrieri A, Wang C, Song S, Ayon RJ, Desai AA, Black SM, Garcia JGN, Makino A, Yuan JX, Lu W, Wang J. PMID: 30358436.
      View in: PubMed   Mentions:
    19. Pulmonary vascular dysfunction in metabolic syndrome. J Physiol. 2019 02; 597(4):1121-1141. Willson C, Watanabe M, Tsuji-Hosokawa A, Makino A. PMID: 30125956.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    20. Overexpression of hexokinase 2 reduces mitochondrial calcium overload in coronary endothelial cells of type 2 diabetic mice. . 2018 06 01; 314(6):C732-C740. Pan M, Han Y, Basu A, Dai A, Si R, Willson C, Balistrieri A, Scott BT, Makino A. PMID: 29513568.
      View in: PubMed   Mentions:
    21. Diabetes Mellitus Associates with Increased Right Ventricular Afterload and Remodeling in Pulmonary Arterial Hypertension. Am J Med. 2018 06; 131(6):702.e7-702.e13. Whitaker ME, Nair V, Sinari S, Dherange PA, Natarajan B, Trutter L, Brittain EL, Hemnes AR, Austin ED, Patel K, Black SM, Garcia JGN, Yuan Md PhD JX, Vanderpool RR, Rischard F, Makino A, Bedrick EJ, Desai AA. PMID: 29421689.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    22. STIM2 (Stromal Interaction Molecule 2)-Mediated Increase in Resting Cytosolic Free Ca2+ Concentration Stimulates PASMC Proliferation in Pulmonary Arterial Hypertension. Hypertension. 2018 03; 71(3):518-529. Song S, Carr SG, McDermott KM, Rodriguez M, Babicheva A, Balistrieri A, Ayon RJ, Wang J, Makino A, Yuan JX. PMID: 29358461.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    23. Akt2 (Protein Kinase B Beta) Stabilizes ATP7A, a Copper Transporter for Extracellular Superoxide Dismutase, in Vascular Smooth Muscle: Novel Mechanism to Limit Endothelial Dysfunction in Type 2 Diabetes Mellitus. Arterioscler Thromb Vasc Biol. 2018 03; 38(3):529-541. Sudhahar V, Okur MN, Bagi Z, O'Bryan JP, Hay N, Makino A, Patel VS, Phillips SA, Stepp D, Ushio-Fukai M, Fukai T. PMID: 29301787.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    24. Hypoxia selectively upregulates cation channels and increases cytosolic [Ca2+] in pulmonary, but not coronary, arterial smooth muscle cells. . 2018 04 01; 314(4):C504-C517. He X, Song S, Ayon RJ, Balisterieri A, Black SM, Makino A, Wier WG, Zang WJ, Yuan JX. PMID: 29351410.
      View in: PubMed   Mentions:
    25. Endothelial HIF-2α contributes to severe pulmonary hypertension due to endothelial-to-mesenchymal transition. . 2018 02 01; 314(2):L256-L275. Tang H, Babicheva A, McDermott KM, Gu Y, Ayon RJ, Song S, Wang Z, Gupta A, Zhou T, Sun X, Dash S, Wang Z, Balistrieri A, Zheng Q, Cordery AG, Desai AA, Rischard F, Khalpey Z, Wang J, Black SM, Garcia JGN, Makino A, Yuan JX. PMID: 29074488.
      View in: PubMed   Mentions:
    26. Chloroquine is a potent pulmonary vasodilator that attenuates hypoxia-induced pulmonary hypertension. Br J Pharmacol. 2017 Nov; 174(22):4155-4172. Wu K, Zhang Q, Wu X, Lu W, Tang H, Liang Z, Gu Y, Song S, Ayon RJ, Wang Z, McDermott KM, Balistrieri A, Wang C, Black SM, Garcia JGN, Makino A, Yuan JX, Wang J. PMID: 28849593.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    27. Hypoxia-induced pulmonary hypertension in type 2 diabetic mice. Pulm Circ. 2017 Mar; 7(1):175-185. Pan M, Han Y, Si R, Guo R, Desai A, Makino A. PMID: 28680577.
      View in: PubMed   Mentions:
    28. Mitochondrial connexin40 regulates mitochondrial calcium uptake in coronary endothelial cells. . 2017 Apr 01; 312(4):C398-C406. Guo R, Si R, Scott BT, Makino A. PMID: 28122731.
      View in: PubMed   Mentions:
    29. Capsaicin-induced Ca2+ signaling is enhanced via upregulated TRPV1 channels in pulmonary artery smooth muscle cells from patients with idiopathic PAH. . 2017 03 01; 312(3):L309-L325. Song S, Ayon RJ, Yamamura A, Yamamura H, Dash S, Babicheva A, Tang H, Sun X, Cordery AG, Khalpey Z, Black SM, Desai AA, Rischard F, McDermott KM, Garcia JG, Makino A, Yuan JX. PMID: 27979859.
      View in: PubMed   Mentions:
    30. Calcium-Sensing Receptor Regulates Cytosolic [Ca 2+ ] and Plays a Major Role in the Development of Pulmonary Hypertension. Front Physiol. 2016; 7:517. Smith KA, Ayon RJ, Tang H, Makino A, Yuan JX. PMID: 27867361.
      View in: PubMed   Mentions:
    31. Isolation of Mouse Coronary Endothelial Cells. J Vis Exp. 2016 07 03; (113). Luo S, Truong AH, Makino A. PMID: 27404385.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    32. Pathogenic role of calcium-sensing receptors in the development and progression of pulmonary hypertension. . 2016 05 01; 310(9):L846-59. Tang H, Yamamura A, Yamamura H, Song S, Fraidenburg DR, Chen J, Gu Y, Pohl NM, Zhou T, Jiménez-Pérez L, Ayon RJ, Desai AA, Goltzman D, Rischard F, Khalpey Z, Black SM, Garcia JG, Makino A, Yuan JX. PMID: 26968768.
      View in: PubMed   Mentions:
    33. ATP promotes cell survival via regulation of cytosolic [Ca2+] and Bcl-2/Bax ratio in lung cancer cells. . 2016 Jan 15; 310(2):C99-114. Song S, Jacobson KN, McDermott KM, Reddy SP, Cress AE, Tang H, Dudek SM, Black SM, Garcia JG, Makino A, Yuan JX. PMID: 26491047.
      View in: PubMed   Mentions:
    34. SGLT inhibitors attenuate NO-dependent vascular relaxation in the pulmonary artery but not in the coronary artery. . 2015 Nov 01; 309(9):L1027-36. Han Y, Cho YE, Ayon R, Guo R, Youssef KD, Pan M, Dai A, Yuan JX, Makino A. PMID: 26361875.
      View in: PubMed   Mentions:
    35. Notch Activation of Ca(2+) Signaling in the Development of Hypoxic Pulmonary Vasoconstriction and Pulmonary Hypertension. Am J Respir Cell Mol Biol. 2015 Sep; 53(3):355-67. Smith KA, Voiriot G, Tang H, Fraidenburg DR, Song S, Yamamura H, Yamamura A, Guo Q, Wan J, Pohl NM, Tauseef M, Bodmer R, Ocorr K, Thistlethwaite PA, Haddad GG, Powell FL, Makino A, Mehta D, Yuan JX. PMID: 25569851.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    36. O-GlcNAcase overexpression reverses coronary endothelial cell dysfunction in type 1 diabetic mice. . 2015 Nov 01; 309(9):C593-9. Makino A, Dai A, Han Y, Youssef KD, Wang W, Donthamsetty R, Scott BT, Wang H, Dillmann WH. PMID: 26269457.
      View in: PubMed   Mentions:
    37. Upregulated expression of STIM2, TRPC6, and Orai2 contributes to the transition of pulmonary arterial smooth muscle cells from a contractile to proliferative phenotype. . 2015 Apr 15; 308(8):C581-93. Fernandez RA, Wan J, Song S, Smith KA, Gu Y, Tauseef M, Tang H, Makino A, Mehta D, Yuan JX. PMID: 25673771.
      View in: PubMed   Mentions:
    38. Deficiency of Akt1, but not Akt2, attenuates the development of pulmonary hypertension. . 2015 Jan 15; 308(2):L208-20. Tang H, Chen J, Fraidenburg DR, Song S, Sysol JR, Drennan AR, Offermanns S, Ye RD, Bonini MG, Minshall RD, Garcia JG, Machado RF, Makino A, Yuan JX. PMID: 25416384.
      View in: PubMed   Mentions:
    39. Flow shear stress enhances intracellular Ca2+ signaling in pulmonary artery smooth muscle cells from patients with pulmonary arterial hypertension. . 2014 Aug 15; 307(4):C373-83. Song S, Yamamura A, Yamamura H, Ayon RJ, Smith KA, Tang H, Makino A, Yuan JX. PMID: 24920677.
      View in: PubMed   Mentions:
    40. In vivo selective expression of thyroid hormone receptor α1 in endothelial cells attenuates myocardial injury in experimental myocardial infarction in mice. . 2014 Aug 01; 307(3):R340-6. Suarez J, Wang H, Scott BT, Ling H, Makino A, Swanson E, Brown JH, Suarez JA, Feinstein S, Diaz-Juarez J, Dillmann WH. PMID: 24848360.
      View in: PubMed   Mentions:
    41. Coronary endothelial dysfunction and mitochondrial reactive oxygen species in type 2 diabetic mice. . 2013 Nov 15; 305(10):C1033-40. Cho YE, Basu A, Dai A, Heldak M, Makino A. PMID: 23986204.
      View in: PubMed   Mentions:
    42. Chronic hypoxia selectively enhances L- and T-type voltage-dependent Ca2+ channel activity in pulmonary artery by upregulating Cav1.2 and Cav3.2. . 2013 Jul 15; 305(2):L154-64. Wan J, Yamamura A, Zimnicka AM, Voiriot G, Smith KA, Tang H, Ayon RJ, Choudhury MS, Ko EA, Wang J, Wang C, Makino A, Yuan JX. PMID: 23686856.
      View in: PubMed   Mentions:
    43. Functional characterization of voltage-dependent Ca(2+) channels in mouse pulmonary arterial smooth muscle cells: divergent effect of ROS. . 2013 Jun 01; 304(11):C1042-52. Ko EA, Wan J, Yamamura A, Zimnicka AM, Yamamura H, Yoo HY, Tang H, Smith KA, Sundivakkam PC, Zeifman A, Ayon RJ, Makino A, Yuan JX. PMID: 23426966.
      View in: PubMed   Mentions:
    44. Dihydropyridine Ca(2+) channel blockers increase cytosolic [Ca(2+)] by activating Ca(2+)-sensing receptors in pulmonary arterial smooth muscle cells. Circ Res. 2013 Feb 15; 112(4):640-50. Yamamura A, Yamamura H, Guo Q, Zimnicka AM, Wan J, Ko EA, Smith KA, Pohl NM, Song S, Zeifman A, Makino A, Yuan JX. PMID: 23300272.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    45. VDAC: old protein with new roles in diabetes. . 2012 Nov 15; 303(10):C1055-60. Sasaki K, Donthamsetty R, Heldak M, Cho YE, Scott BT, Makino A. PMID: 22972802.
      View in: PubMed   Mentions:
    46. Apolipoprotein E enhances endothelial-NO production by modulating caveolin 1 interaction with endothelial NO synthase. Hypertension. 2012 Oct; 60(4):1040-6. Yue L, Bian JT, Grizelj I, Cavka A, Phillips SA, Makino A, Mazzone T. PMID: 22914792.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    47. STIM1 restores coronary endothelial function in type 1 diabetic mice. Circ Res. 2012 Oct 12; 111(9):1166-75. Estrada IA, Donthamsetty R, Debski P, Zhou MH, Zhang SL, Yuan JX, Han W, Makino A. PMID: 22896585.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    48. Enhanced Ca(2+)-sensing receptor function in idiopathic pulmonary arterial hypertension. Circ Res. 2012 Aug 03; 111(4):469-81. Yamamura A, Guo Q, Yamamura H, Zimnicka AM, Pohl NM, Smith KA, Fernandez RA, Zeifman A, Makino A, Dong H, Yuan JX. PMID: 22730443.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    49. The role of oxysterols in control of endothelial stiffness. J Lipid Res. 2012 Jul; 53(7):1348-58. Shentu TP, Singh DK, Oh MJ, Sun S, Sadaat L, Makino A, Mazzone T, Subbaiah PV, Cho M, Levitan I. PMID: 22496390.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    50. Thyroid hormone receptor-α and vascular function. . 2012 May 01; 302(9):C1346-52. Makino A, Wang H, Scott BT, Yuan JX, Dillmann WH. PMID: 22322976.
      View in: PubMed   Mentions:
    51. Mitochondrial function in vascular endothelial cell in diabetes. J Smooth Muscle Res. 2012; 48(1):1-26. Pangare M, Makino A. PMID: 22504486.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    52. Fenfluramine-induced gene dysregulation in human pulmonary artery smooth muscle and endothelial cells. Pulm Circ. 2011 Jul-Sep; 1(3):405-18. Yao W, Mu W, Zeifman A, Lofti M, Remillard CV, Makino A, Perkins DL, Garcia JG, Yuan JX, Zhang W. PMID: 22140631.
      View in: PubMed   Mentions:
    53. Endothelial and smooth muscle cell ion channels in pulmonary vasoconstriction and vascular remodeling. Compr Physiol. 2011 Jul; 1(3):1555-602. Makino A, Firth AL, Yuan JX. PMID: 23733654.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    54. Tension Measurement in Isolated Rat and Mouse Pulmonary Artery. Drug Discov Today Dis Models. 2010; 7(3-4):123-130. Ko EA, Song MY, Donthamsetty R, Makino A, Yuan JX. PMID: 23175638.
      View in: PubMed   Mentions:
    55. Role of reactive oxygen species and redox in regulating the function of transient receptor potential channels. Antioxid Redox Signal. 2011 Sep 15; 15(6):1549-65. Song MY, Makino A, Yuan JX. PMID: 21126186.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    56. Regulation of mitochondrial morphology and function by O-GlcNAcylation in neonatal cardiac myocytes. . 2011 Jun; 300(6):R1296-302. Makino A, Suarez J, Gawlowski T, Han W, Wang H, Scott BT, Dillmann WH. PMID: 21346246.
      View in: PubMed   Mentions:
    57. STIM2 Contributes to Enhanced Store-operated Ca Entry in Pulmonary Artery Smooth Muscle Cells from Patients with Idiopathic Pulmonary Arterial Hypertension. Pulm Circ. 2011; 1(1):84-94. Song MY, Makino A, Yuan JX. PMID: 21709766.
      View in: PubMed   Mentions:
    58. Mitochondrial fragmentation and superoxide anion production in coronary endothelial cells from a mouse model of type 1 diabetes. Diabetologia. 2010 Aug; 53(8):1783-94. Makino A, Scott BT, Dillmann WH. PMID: 20461356.
      View in: PubMed   Mentions: 93     Fields:    Translation:AnimalsCells
    59. Notch3 signaling promotes the development of pulmonary arterial hypertension. Nat Med. 2009 Nov; 15(11):1289-97. Li X, Zhang X, Leathers R, Makino A, Huang C, Parsa P, Macias J, Yuan JX, Jamieson SW, Thistlethwaite PA. PMID: 19855400.
      View in: PubMed   Mentions: 129     Fields:    Translation:HumansAnimalsCells
    60. Thyroid hormone receptor-beta is associated with coronary angiogenesis during pathological cardiac hypertrophy. Endocrinology. 2009 Apr; 150(4):2008-15. Makino A, Suarez J, Wang H, Belke DD, Scott BT, Dillmann WH. PMID: 19074585.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    61. Alterations in mitochondrial function and cytosolic calcium induced by hyperglycemia are restored by mitochondrial transcription factor A in cardiomyocytes. . 2008 Dec; 295(6):C1561-8. Suarez J, Hu Y, Makino A, Fricovsky E, Wang H, Dillmann WH. PMID: 19060297.
      View in: PubMed   Mentions:
    62. p75 neurotrophin receptor regulates agonist-induced pulmonary vasoconstriction. . 2008 Oct; 295(4):H1529-38. Xu M, Remillard CV, Sachs BD, Makino A, Platoshyn O, Yao W, Dillmann WH, Akassoglou K, Yuan JX. PMID: 18689502.
      View in: PubMed   Mentions:
    63. Downregulation of connexin40 is associated with coronary endothelial cell dysfunction in streptozotocin-induced diabetic mice. . 2008 Jul; 295(1):C221-30. Makino A, Platoshyn O, Suarez J, Yuan JX, Dillmann WH. PMID: 18463230.
      View in: PubMed   Mentions:
    64. Nitrosyl-cobinamide, a new and direct nitric oxide releasing drug effective in vivo. Exp Biol Med (Maywood). 2007 Dec; 232(11):1432-40. Broderick KE, Alvarez L, Balasubramanian M, Belke DD, Makino A, Chan A, Woods VL, Dillmann WH, Sharma VS, Pilz RB, Bigby TD, Boss GR. PMID: 18040067.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    65. Characterization of agonist-induced vasoconstriction in mouse pulmonary artery. . 2008 Jan; 294(1):H220-8. Xu M, Platoshyn O, Makino A, Dillmann WH, Akassoglou K, Remillard CV, Yuan JX. PMID: 17982012.
      View in: PubMed   Mentions:
    66. Mechanotransduction in leukocyte activation: a review. Biorheology. 2007; 44(4):221-49. Makino A, Shin HY, Komai Y, Fukuda S, Coughlin M, Sugihara-Seki M, Schmid-Schönbein GW. PMID: 18094448.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    67. Effects of anthocyanidin derivative (HK-008) on relaxation in rat perfused mesenterial bed. J Smooth Muscle Res. 2006 Jun; 42(2-3):75-88. Kamata K, Makino A, Kanie N, Oda S, Matsumoto T, Kobayashi T, Kikuchi T, Nishimura M, Honda T. PMID: 17001114.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    68. G protein-coupled receptors serve as mechanosensors for fluid shear stress in neutrophils. . 2006 Jun; 290(6):C1633-9. Makino A, Prossnitz ER, Bünemann M, Wang JM, Yao W, Schmid-Schönbein GW. PMID: 16436471.
      View in: PubMed   Mentions:
    69. Control of neutrophil pseudopods by fluid shear: role of Rho family GTPases. . 2005 Apr; 288(4):C863-71. Makino A, Glogauer M, Bokoch GM, Chien S, Schmid-Schönbein GW. PMID: 15561759.
      View in: PubMed   Mentions:
    70. Increased renal medullary H2O2 leads to hypertension. Hypertension. 2003 Jul; 42(1):25-30. Makino A, Skelton MM, Zou AP, Cowley AW. PMID: 12782642.
      View in: PubMed   Mentions: 39     Fields:    Translation:Animals
    71. Effects of chronic administration of L-arginine on vasoactive responses induced by endothelin-1 and its plasma level in streptozotocin-induced diabetic rats. J Smooth Muscle Res. 2002 Oct; 38(4-5):101-15. Makino A, Kamata K. PMID: 12596889.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    72. Increased renal medullary oxidative stress produces hypertension. Hypertension. 2002 Feb; 39(2 Pt 2):667-72. Makino A, Skelton MM, Zou AP, Roman RJ, Cowley AW. PMID: 11882628.
      View in: PubMed   Mentions: 46     Fields:    Translation:Animals
    73. Mechanisms underlying increased release of endothelin-1 from aorta in diabetic rats. Peptides. 2001 Apr; 22(4):639-45. Makino A, Oda S, Kamata K. PMID: 11311735.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    74. Mechanisms underlying the attenuation of endothelium-dependent vasodilatation in the mesenteric arterial bed of the streptozotocin-induced diabetic rat. Br J Pharmacol. 2000 Jun; 130(3):549-56. Makino A, Ohuchi K, Kamata K. PMID: 10821782.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    75. Time-course changes in plasma endothelin-1 and its effects on the mesenteric arterial bed in streptozotocin-induced diabetic rats. Diabetes Obes Metab. 2000 Jan; 2(1):47-55. Makino A, Kamata K. PMID: 11220354.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    76. Possible modulation by endothelin-1, nitric oxide, prostaglandin I2 and thromboxane A2 of vasoconstriction induced by an alpha-agonist in mesenteric arterial bed from diabetic rats. Diabetologia. 1998 Dec; 41(12):1410-8. Makino A, Kamata K. PMID: 9867207.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    77. Elevated plasma endothelin-1 level in streptozotocin-induced diabetic rats and responsiveness of the mesenteric arterial bed to endothelin-1. Br J Pharmacol. 1998 Mar; 123(6):1065-72. Makino A, Kamata K. PMID: 9559887.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    78. A comparative study on the rat aorta and mesenteric arterial bed of the possible role of nitric oxide in the desensitization of the vasoconstrictor response to an alpha 1-adrenoceptor agonist. Br J Pharmacol. 1997 Apr; 120(7):1221-8. Kamata K, Makino A. PMID: 9105696.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    Ayako's Networks
    Concepts (360)
    Derived automatically from this person's publications.
    _
    Co-Authors (28)
    People in Profiles who have published with this person.
    _
    Similar People (60)
    People who share similar concepts with this person.
    _
    Same Department
    Search Department
    _