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Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes. Nature. 2023 Nov; 623(7987):616-624.
Zhang F, Jonsson AH, Nathan A, Millard N, Curtis M, Xiao Q, Gutierrez-Arcelus M, Apruzzese W, Watts GFM, Weisenfeld D, Nayar S, Rangel-Moreno J, Meednu N, Marks KE, Mantel I, Kang JB, Rumker L, Mears J, Slowikowski K, Weinand K, Orange DE, Geraldino-Pardilla L, Deane KD, Tabechian D, Ceponis A, Firestein GS, Maybury M, Sahbudin I, Ben-Artzi A, Mandelin AM, Nerviani A, Lewis MJ, Rivellese F, Pitzalis C, Hughes LB, Horowitz D, DiCarlo E, Gravallese EM, Boyce BF, Accelerating Medicines Partnership: RA/SLE Network, Moreland LW, Goodman SM, Perlman H, Holers VM, Liao KP, Filer A, Bykerk VP, Wei K, Rao DA, Donlin LT, Anolik JH, Brenner MB, Raychaudhuri S. PMID: 37938773; PMCID: PMC10651487.
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41 Fields:
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Differential DNA Methylation of Networked Signaling, Transcriptional, Innate and Adaptive Immunity, and Osteoclastogenesis Genes and Pathways in Gout. Arthritis Rheumatol. 2020 05; 72(5):802-814.
Wang Z, Zhao Y, Phipps-Green A, Liu-Bryan R, Ceponis A, Boyle DL, Wang J, Merriman TR, Wang W, Terkeltaub R. PMID: 31738005; PMCID: PMC7323903.
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14 Fields:
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PTP4A1 promotes TGFβ signaling and fibrosis in systemic sclerosis. Nat Commun. 2017 10 20; 8(1):1060.
Sacchetti C, Bai Y, Stanford SM, Di Benedetto P, Cipriani P, Santelli E, Piera-Velazquez S, Chernitskiy V, Kiosses WB, Ceponis A, Kaestner KH, Boin F, Jimenez SA, Giacomelli R, Zhang ZY, Bottini N. PMID: 29057934; PMCID: PMC5651906.
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25 Fields:
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HumansAnimalsCells
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Efficacy and safety of point-of-care ultrasound-guided intra-articular corticosteroid joint injections in patients with haemophilic arthropathy. Haemophilia. 2017 Jan; 23(1):135-143.
Martin EJ, Cooke EJ, Ceponis A, Barnes RF, Moran CM, Holle S, Hughes TH, Moore RE, von Drygalski A. PMID: 27486060.
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8 Fields:
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Humans
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Salivary Gland Ultrasonography as a Diagnostic Tool for Secondary Sjögren Syndrome in Rheumatoid Arthritis. J Rheumatol. 2015 Jul; 42(7):1119-22.
Das S, Huynh D, Yang H, Ceponis A, Kavanaugh A. PMID: 25934827.
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1 Fields:
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Humans
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Point-of-care musculoskeletal ultrasound is critical for the diagnosis of hemarthroses, inflammation and soft tissue abnormalities in adult patients with painful haemophilic arthropathy. Haemophilia. 2015 Jul; 21(4):530-7.
Kidder W, Nguyen S, Larios J, Bergstrom J, Ceponis A, von Drygalski A. PMID: 25623830.
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31 Fields:
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Humans
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Utility of the ultrasound examination of the hand and wrist joints in the management of established rheumatoid arthritis. Arthritis Care Res (Hoboken). 2014 Feb; 66(2):236-44.
Ceponis A, Onishi M, Bluestein HG, Kalunian K, Townsend J, Kavanaugh A. PMID: 23983173.
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12 Fields:
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Humans
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Rapid musculoskeletal ultrasound for painful episodes in adult haemophilia patients. Haemophilia. 2013 Sep; 19(5):790-8.
Ceponis A, Wong-Sefidan I, Glass CS, von Drygalski A. PMID: 23672827.
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38 Fields:
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Humans
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Use of methotrexate in patients with psoriatic arthritis. Clin Exp Rheumatol. 2010 Sep-Oct; 28(5 Suppl 61):S132-7.
Ceponis A, Kavanaugh A. PMID: 21044447.
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10 Fields:
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Treatment of psoriatic arthritis with biological agents. Semin Cutan Med Surg. 2010 Mar; 29(1):56-62.
Ceponis A, Kavanaugh A. PMID: 20430309.
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4 Fields:
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Humans
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Cartilage oligomeric matrix protein (COMP) is modified by intra-articular liposomal clodronate in an experimental model of arthritis. Clin Exp Rheumatol. 2006 Nov-Dec; 24(6):622-8.
Gomez-Barrena E, Lindroos L, Ceponis A, López-Franco M, Sanchez-Pernaute O, Mönkkönen J, Salo J, Herrero-Beaumont G, Konttinen Y. PMID: 17207376.
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5 Fields:
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Animals
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Vascular damage and lack of angiogenesis in systemic sclerosis skin. Clin Rheumatol. 2003 Sep; 22(3):196-202.
Konttinen YT, Mackiewicz Z, Ruuttila P, Ceponis A, Sukura A, Povilenaite D, Hukkanen M, Virtanen I. PMID: 14505210.
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13 Fields:
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Humans
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Increased but imbalanced expression of VEGF and its receptors has no positive effect on angiogenesis in systemic sclerosis skin. Clin Exp Rheumatol. 2002 Sep-Oct; 20(5):641-6.
Mackiewicz Z, Sukura A, Povilenaité D, Ceponis A, Virtanen I, Hukkanen M, Konttinen YT. PMID: 12412194.
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21 Fields:
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HumansAnimals
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Collagenase-3 (MMP-13) and its activators in rheumatoid arthritis: localization in the pannus-hard tissue junction and inhibition by alendronate. Matrix Biol. 1999 Aug; 18(4):401-12.
Konttinen YT, Salo T, Hanemaaijer R, Valleala H, Sorsa T, Sutinen M, Ceponis A, Xu JW, Santavirta S, Teronen O, López-Otín C. PMID: 10517187.
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15 Fields:
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Humans
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A comparative quantitative morphometric study of cell apoptosis in synovial membranes in psoriatic, reactive and rheumatoid arthritis. Rheumatology (Oxford). 1999 May; 38(5):431-40.
Ceponis A, Hietanen J, Tamulaitiene M, Partsch G, Pätiälä H, Konttinen YT. PMID: 10371281.
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7 Fields:
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HumansCells
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Expression of stem cell factor (SCF) and SCF receptor (c-kit) in synovial membrane in arthritis: correlation with synovial mast cell hyperplasia and inflammation. J Rheumatol. 1998 Dec; 25(12):2304-14.
Ceponis A, Konttinen YT, Takagi M, Xu JW, Sorsa T, Matucci-Cerinic M, Santavirta S, Bankl HC, Valent P. PMID: 9858422.
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15 Fields:
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HumansCells
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New collagenolytic enzymes/cascade identified at the pannus-hard tissue junction in rheumatoid arthritis: destruction from above. Matrix Biol. 1998 Dec; 17(8-9):585-601.
Konttinen YT, Ceponis A, Takagi M, Ainola M, Sorsa T, Sutinen M, Salo T, Ma J, Santavirta S, Seiki M. PMID: 9923652.
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23 Fields:
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Matrix metalloproteinase (MMP)-9 type IV collagenase/gelatinase implicated in the pathogenesis of Sjögren's syndrome. Matrix Biol. 1998 Oct; 17(5):335-47.
Konttinen YT, Halinen S, Hanemaaijer R, Sorsa T, Hietanen J, Ceponis A, Xu JW, Manthorpe R, Whittington J, Larsson A, Salo T, Kjeldsen L, Stenman UH, Eisen AZ. PMID: 9822200.
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19 Fields:
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High levels of expression of collagenase-3 (MMP-13) in pathological conditions associated with a foreign-body reaction. J Bone Joint Surg Br. 1998 Jul; 80(4):701-10.
Imai S, Konttinen YT, Jumppanen M, Lindy O, Ceponis A, Kemppinen P, Sorsa T, Santavirta S, Xu JW, Lopéz-Otín C. PMID: 9699841.
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10 Fields:
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HumansCells
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Synovial lining, endothelial and inflammatory mononuclear cell proliferation in synovial membranes in psoriatic and reactive arthritis: a comparative quantitative morphometric study. Br J Rheumatol. 1998 Feb; 37(2):170-8.
Ceponis A, Konttinen YT, Imai S, Tamulaitiene M, Li TF, Xu JW, Hietanen J, Santavirta S, Fassbender HG. PMID: 9569072.
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13 Fields:
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HumansCells
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Interleukin-11 (IL-11) in aseptic loosening of total hip replacement (THR). Scand J Rheumatol. 1998; 27(5):363-7.
Xu JW, Li TF, Partsch G, Ceponis A, Santavirta S, Konttinen YT. PMID: 9808400.
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9 Fields:
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HumansPHPublic Health
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Matrix metalloproteinase 13 (collagenase 3) in human rheumatoid synovium. Arthritis Rheum. 1997 Aug; 40(8):1391-9.
Lindy O, Konttinen YT, Sorsa T, Ding Y, Santavirta S, Ceponis A, López-Otín C. PMID: 9259418.
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55 Fields:
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Complement in acute and chronic arthritides: assessment of C3c, C9, and protectin (CD59) in synovial membrane. Ann Rheum Dis. 1996 Dec; 55(12):888-94.
Konttinen YT, Ceponis A, Meri S, Vuorikoski A, Kortekangas P, Sorsa T, Sukura A, Santavirta S. PMID: 9014582; PMCID: PMC1010340.
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40 Fields:
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Aberrant vascularity and von Willebrand factor distribution in inflamed synovial membrane. J Rheumatol. 1996 Nov; 23(11):1880-6.
Ceponis A, Konttinen YT, MacKevicius Z, Solovieva SA, Hukkanen M, Tamulaitiene M, Matulis A, Santavirta S. PMID: 8923360.
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4 Fields:
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Humans
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Tumor necrosis factor-alpha (TNF-alpha) in loosening of total hip replacement (THR). Clin Exp Rheumatol. 1996 Nov-Dec; 14(6):643-8.
Xu JW, Konttinen YT, Lassus J, Natah S, Ceponis A, Solovieva S, Aspenberg P, Santavirta S. PMID: 8978959.
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21 Fields:
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Mast cells in loosening of totally replaced hips. Clin Orthop Relat Res. 1996 Jan; (322):158-65.
Solovieva SA, Ceponis A, Konttinen YT, Takagi M, Suda A, Eklund KK, Sorsa T, Santavirta S. PMID: 8542692.
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6 Fields:
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HumansCells