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Anthony Horner

TitleAssociate Professor of Medicine
InstitutionUniversity of California San Diego
DepartmentMedicine
Address9500 Gilman Drive #0663
La Jolla CA 92093
Phone858-534-5435
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    Collapse Research 
    Collapse Research Activities and Funding
    Ambient TLR Ligand Exposures and the Genesis of Asthma
    NIH/NIAID R01AI061772Aug 5, 2004 - Jan 31, 2010
    Role: Principal Investigator
    ALLERGEN GENE VACCINATION IN MOUSE MODEL OF FOOD ALLERGY
    NIH/NIAID K08AI001490Feb 1, 1998 - Jan 31, 2002
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Chandra S, Wingender G, Greenbaum JA, Khurana A, Gholami AM, Ganesan AP, Rosenbach M, Jaffee K, Gern JE, Wood R, O'Connor G, Sandel M, Kattan M, Bacharier L, Togias A, Horner A, Kronenberg M. Development of Asthma in Inner-City Children: Possible Roles of MAIT Cells and Variation in the Home Environment. J Immunol. 2018 Mar 15; 200(6):1995-2003. PMID: 29431692.
      View in: PubMed
    2. Kim H, Tse K, Levin L, Bernstein D, Reponen T, LeMasters G, Lummus Z, Horner A. House dust bioactivities predict skin prick test reactivity for children with high risk of allergy. J Allergy Clin Immunol. 2012 Jun; 129(6):1529-37.e2. PMID: 22385634; PMCID: PMC3582404.
    3. Wingender G, Rogers P, Batzer G, Lee MS, Bai D, Pei B, Khurana A, Kronenberg M, Horner A. Invariant NKT cells are required for airway inflammation induced by environmental antigens. J Exp Med. 2011 Jun 06; 208(6):1151-62. PMID: 21624935; PMCID: PMC3173256.
    4. Lee SM, Batzer G, Ng N, Lam D, Pattar SS, Patel ND, Horner A. Regulatory T cells contribute to allergen tolerance induced by daily airway immunostimulant exposures. Am J Respir Cell Mol Biol. 2011 Mar; 44(3):341-9. PMID: 20448052; PMCID: PMC3095935.
    5. Horner A. Regulation of aeroallergen immunity by the innate immune system: laboratory evidence for a new paradigm. J Innate Immun. 2010; 2(2):107-13. PMID: 20375629; PMCID: PMC2840247.
    6. Brydges SD, Mueller JL, McGeough MD, Pena CA, Misaghi A, Gandhi C, Putnam CD, Boyle DL, Firestein GS, Horner A, Soroosh P, Watford WT, O'Shea JJ, Kastner DL, Hoffman HM. Inflammasome-mediated disease animal models reveal roles for innate but not adaptive immunity. Immunity. 2009 Jun 19; 30(6):875-87. PMID: 19501000; PMCID: PMC2759865.
    7. Tse K, Horner A. Allergen tolerance versus the allergic march: the hygiene hypothesis revisited. Curr Allergy Asthma Rep. 2008 Nov; 8(6):475-83. PMID: 18940137; PMCID: PMC2869282.
    8. Lam D, Ng N, Lee S, Batzer G, Horner A. Airway house dust extract exposures modify allergen-induced airway hypersensitivity responses by TLR4-dependent and independent pathways. J Immunol. 2008 Aug 15; 181(4):2925-32. PMID: 18684984; PMCID: PMC2587103.
    9. Tse K, Horner A. Defining a role for ambient TLR ligand exposures in the genesis and prevention of allergic diseases. Semin Immunopathol. 2008 Feb; 30(1):53-62. PMID: 17989979.
      View in: PubMed
    10. Tse K, Horner A. Update on toll-like receptor-directed therapies for human disease. Ann Rheum Dis. 2007 Nov; 66 Suppl 3:iii77-80. PMID: 17934102; PMCID: PMC2095280.
    11. Batzer G, Lam DP, Paulus P, Boasen J, Ng N, Horner A. Using house dust extracts to understand the immunostimulatory activities of living environments. Immunobiology. 2007; 212(6):491-8. PMID: 17544833; PMCID: PMC1950943.
    12. Horner A. Update on toll-like receptor ligands and allergy: implications for immunotherapy. Curr Allergy Asthma Rep. 2006 Sep; 6(5):395-401. PMID: 16899201.
      View in: PubMed
    13. Ng N, Lam D, Paulus P, Batzer G, Horner A. House dust extracts have both TH2 adjuvant and tolerogenic activities. J Allergy Clin Immunol. 2006 May; 117(5):1074-81. PMID: 16675335.
      View in: PubMed
    14. Horner A. Toll-like receptor ligands and atopy: a coin with at least two sides. J Allergy Clin Immunol. 2006 May; 117(5):1133-40. PMID: 16675343.
      View in: PubMed
    15. Boasen J, Chisholm D, Lebet L, Akira S, Horner A. House dust extracts elicit Toll-like receptor-dependent dendritic cell responses. J Allergy Clin Immunol. 2005 Jul; 116(1):185-91. PMID: 15990793.
      View in: PubMed
    16. Horner A, Redecke V, Raz E. Toll-like receptor ligands: hygiene, atopy and therapeutic implications. Curr Opin Allergy Clin Immunol. 2004 Dec; 4(6):555-61. PMID: 15640699.
      View in: PubMed
    17. Rhee CS, Libet L, Chisholm D, Takabayashi K, Baird S, Bigby TD, Lee CH, Horner A, Raz E. Allergen-independent immunostimulatory sequence oligodeoxynucleotide therapy attenuates experimental allergic rhinitis. Immunology. 2004 Sep; 113(1):106-13. PMID: 15312141; PMCID: PMC1782540.
    18. Datta SK, Cho HJ, Takabayashi K, Horner A, Raz E. Antigen-immunostimulatory oligonucleotide conjugates: mechanisms and applications. Immunol Rev. 2004 Jun; 199:217-26. PMID: 15233737.
      View in: PubMed
    19. Chisholm D, Libet L, Hayashi T, Horner A. Airway peptidoglycan and immunostimulatory DNA exposures have divergent effects on the development of airway allergen hypersensitivities. J Allergy Clin Immunol. 2004 Mar; 113(3):448-54. PMID: 15007346.
      View in: PubMed
    20. Horner A, Raz E. Do microbes influence the pathogenesis of allergic diseases? Building the case for Toll-like receptor ligands. Curr Opin Immunol. 2003 Dec; 15(6):614-9. PMID: 14630193.
      View in: PubMed
    21. Takabayashi K, Libet L, Chisholm D, Zubeldia J, Horner A. Intranasal immunotherapy is more effective than intradermal immunotherapy for the induction of airway allergen tolerance in Th2-sensitized mice. J Immunol. 2003 Apr 01; 170(7):3898-905. PMID: 12646659.
      View in: PubMed
    22. Spiegelberg HL, Horner A, Takabayashi K, Raz E. Allergen-immunostimulatory oligodeoxynucleotide conjugate: a novel allergoid for immunotherapy. Curr Opin Allergy Clin Immunol. 2002 Dec; 2(6):547-51. PMID: 14752340.
      View in: PubMed
    23. Horner A, Raz E. Immunostimulatory sequence oligodeoxynucleotide-based vaccination and immunomodulation: two unique but complementary strategies for the treatment of allergic diseases. J Allergy Clin Immunol. 2002 Nov; 110(5):706-12. PMID: 12417878.
      View in: PubMed
    24. Horner A, Takabayashi K, Beck L, Sharma B, Zubeldia J, Baird S, Tuck S, Libet L, Spiegelberg HL, Liu FT, Raz E. Optimized conjugation ratios lead to allergen immunostimulatory oligodeoxynucleotide conjugates with retained immunogenicity and minimal anaphylactogenicity. J Allergy Clin Immunol. 2002 Sep; 110(3):413-20. PMID: 12209088.
      View in: PubMed
    25. Cho HJ, Hayashi T, Datta SK, Takabayashi K, Van Uden JH, Horner A, Corr M, Raz E. IFN-alpha beta promote priming of antigen-specific CD8+ and CD4+ T lymphocytes by immunostimulatory DNA-based vaccines. J Immunol. 2002 May 15; 168(10):4907-13. PMID: 11994440.
      View in: PubMed
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