Loading...
Sign in to edit your profile (add interests, mentoring, photo, etc.)

    Anne Murphy

    TitleAdjunct Professor
    SchoolUniversity of California, San Diego
    DepartmentPharmacology
    Address9500 Gilman Drive #0636
    CA La Jolla 92093
    Phone858-246-0573
    vCardDownload vCard

      Collapse Biography 
      Collapse Education and Training
      George Washington UniversityPh.D.School of Medicine

      Collapse Overview 

      Collapse Research 
      Collapse Research Activities and Funding
      Targeting the mitochondrial pyruvate carrier to treat neurodegenerative disease
      NIH/NINDS R01NS087611May 1, 2014 - Apr 30, 2019
      Role: Principal Investigator
      PPAR-sparing/free Thiazolidinediones for Treatment of Diabetes
      NIH/NIDDK R42DK081298May 1, 2009 - Mar 31, 2012
      Role: Principal Investigator
      OSTEOARTHRITIS/CHONDROCALCINOSIS: MITOCHONDRIAL THERAPY
      NIH/NIAMS R43AR049145Sep 24, 2003 - May 31, 2004
      Role: Principal Investigator
      PKA & PKC Targeting Mechanisms (Program Project)
      NIH/NIDDK P01DK054441Dec 15, 1998 - Mar 31, 2018
      Role: Co-Investigator
      BC1-2 IN HYPOXIA/REOXYGENATION
      NIH/NINDS R01NS034154Aug 10, 1996 - Apr 30, 2000
      Role: Principal Investigator

      Collapse ORNG Applications 
      Collapse Websites

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Orogo AM, Gonzalez ER, Kubli DA, Baptista IL, Ong SB, Prolla TA, Sussman MA, Murphy A, Gustafsson ÅB. Accumulation of mitochondrial DNA mutations disrupts cardiac progenitor cell function and reduces survival. J Biol Chem. 2017 Jul 07; 292(27):11348. PMID: 28687597.
        View in: PubMed
      2. Hashem SI, Murphy A, Divakaruni AS, Klos ML, Nelson BC, Gault EC, Rowland TJ, Perry CN, Gu Y, Dalton ND, Bradford WH, Devaney EJ, Peterson KL, Jones KL, Taylor MRG, Chen J, Chi NC, Adler ED. Impaired mitophagy facilitates mitochondrial damage in Danon disease. J Mol Cell Cardiol. 2017 May 16; 108:86-94. PMID: 28526246.
        View in: PubMed
      3. Divakaruni AS, Wallace M, Buren C, Martyniuk K, Andreyev AY, Li E, Fields JA, Cordes T, Reynolds IJ, Bloodgood BL, Raymond LA, Metallo CM, Murphy A. Inhibition of the mitochondrial pyruvate carrier protects from excitotoxic neuronal death. J Cell Biol. 2017 04 03; 216(4):1091-1105. PMID: 28254829.
        View in: PubMed
      4. Parker SJ, Svensson RU, Divakaruni AS, Lefebvre AE, Murphy A, Shaw RJ, Metallo CM. LKB1 promotes metabolic flexibility in response to energy stress. Metab Eng. 2017 Sep; 43(Pt B):208-217. PMID: 28034771.
        View in: PubMed
      5. Zhang H, Badur MG, Divakaruni AS, Parker SJ, Jäger C, Hiller K, Murphy A, Metallo CM. Distinct Metabolic States Can Support Self-Renewal and Lipogenesis in Human Pluripotent Stem Cells under Different Culture Conditions. Cell Rep. 2016 Aug 09; 16(6):1536-1547. PMID: 27477285; PMCID: PMC4981511.
        View in: PubMed, PubMed Central
      6. Garcia-Carbonell R, Divakaruni AS, Lodi A, Vicente-Suarez I, Saha A, Cheroutre H, Boss GR, Tiziani S, Murphy A, Guma M. Critical Role of Glucose Metabolism in Rheumatoid Arthritis Fibroblast-like Synoviocytes. Arthritis Rheumatol. 2016 Jul; 68(7):1614-26. PMID: 26815411; PMCID: PMC4963240.
        View in: PubMed, PubMed Central
      7. Cordes T, Wallace M, Michelucci A, Divakaruni AS, Sapcariu SC, Sousa C, Koseki H, Cabrales P, Murphy A, Hiller K, Metallo CM. Immunoresponsive Gene 1 and Itaconate Inhibit Succinate Dehydrogenase to Modulate Intracellular Succinate Levels. J Biol Chem. 2016 Jul 01; 291(27):14274-84. PMID: 27189937; PMCID: PMC4933182 [Available on 07/01/17].
        View in: PubMed, PubMed Central
      8. Ding B, Parmigiani A, Divakaruni AS, Archer K, Murphy A, Budanov AV. Sestrin2 is induced by glucose starvation via the unfolded protein response and protects cells from non-canonical necroptotic cell death. Sci Rep. 2016 Mar 02; 6:22538. PMID: 26932729; PMCID: PMC4773760.
        View in: PubMed, PubMed Central
      9. Fields JA, Serger E, Campos S, Divakaruni AS, Kim C, Smith K, Trejo M, Adame A, Spencer B, Rockenstein E, Murphy A, Ellis RJ, Letendre S, Grant I, Masliah E. HIV alters neuronal mitochondrial fission/fusion in the brain during HIV-associated neurocognitive disorders. Neurobiol Dis. 2016 Feb; 86:154-69. PMID: 26611103; PMCID: PMC4713337.
        View in: PubMed, PubMed Central
      10. Green CR, Wallace M, Divakaruni AS, Phillips SA, Murphy A, Ciaraldi TP, Metallo CM. Branched-chain amino acid catabolism fuels adipocyte differentiation and lipogenesis. Nat Chem Biol. 2016 Jan; 12(1):15-21. PMID: 26571352; PMCID: PMC4684771.
        View in: PubMed, PubMed Central
      11. Giacco F, Du X, Carratú A, Gerfen GJ, D'Apolito M, Giardino I, Rasola A, Marin O, Divakaruni AS, Murphy A, Shah MS, Brownlee M. GLP-1 Cleavage Product Reverses Persistent ROS Generation After Transient Hyperglycemia by Disrupting an ROS-Generating Feedback Loop. Diabetes. 2015 Sep; 64(9):3273-84. PMID: 26294429; PMCID: PMC4542449.
        View in: PubMed, PubMed Central
      12. Wilderman A, Guo Y, Divakaruni AS, Perkins G, Zhang L, Murphy A, Taylor SS, Insel PA. Proteomic and Metabolic Analyses of S49 Lymphoma Cells Reveal Novel Regulation of Mitochondria by cAMP and Protein Kinase A. J Biol Chem. 2015 Sep 04; 290(36):22274-86. PMID: 26203188; PMCID: PMC4571978.
        View in: PubMed, PubMed Central
      13. Orogo AM, Gonzalez ER, Kubli DA, Baptista IL, Ong SB, Prolla TA, Sussman MA, Murphy A, Gustafsson ÅB. Accumulation of Mitochondrial DNA Mutations Disrupts Cardiac Progenitor Cell Function and Reduces Survival. J Biol Chem. 2015 Sep 04; 290(36):22061-75. PMID: 26183775; PMCID: PMC4571958.
        View in: PubMed, PubMed Central
      14. Andreyev AY, Kushnareva YE, Murphy A, Starkov AA. Mitochondrial ROS Metabolism: 10 Years Later. Biochemistry (Mosc). 2015 May; 80(5):517-31. PMID: 26071769; PMCID: PMC4511471.
        View in: PubMed, PubMed Central
      15. Westenbrink BD, Ling H, Divakaruni AS, Gray CB, Zambon AC, Dalton ND, Peterson KL, Gu Y, Matkovich SJ, Murphy A, Miyamoto S, Dorn GW, Heller Brown J. Mitochondrial reprogramming induced by CaMKIId mediates hypertrophy decompensation. Circ Res. 2015 Feb 27; 116(5):e28-39. PMID: 25605649; PMCID: PMC4344921.
        View in: PubMed, PubMed Central
      16. Andreyev AY, Tsui HS, Milne GL, Shmanai VV, Bekish AV, Fomich MA, Pham MN, Nong Y, Murphy A, Clarke CF, Shchepinov MS. Isotope-reinforced polyunsaturated fatty acids protect mitochondria from oxidative stress. Free Radic Biol Med. 2015 May; 82:63-72. PMID: 25578654.
        View in: PubMed
      17. Vacanti NM, Divakaruni AS, Green CR, Parker SJ, Henry RR, Ciaraldi TP, Murphy A, Metallo CM. Regulation of substrate utilization by the mitochondrial pyruvate carrier. Mol Cell. 2014 Nov 06; 56(3):425-35. PMID: 25458843; PMCID: PMC4267523.
        View in: PubMed, PubMed Central
      18. White AT, Philp A, Fridolfsson HN, Schilling JM, Murphy A, Hamilton DL, McCurdy CE, Patel HH, Schenk S. High-fat diet-induced impairment of skeletal muscle insulin sensitivity is not prevented by SIRT1 overexpression. Am J Physiol Endocrinol Metab. 2014 Nov 01; 307(9):E764-72. PMID: 25159328; PMCID: PMC4216952.
        View in: PubMed, PubMed Central
      19. Divakaruni AS, Rogers GW, Murphy A. Measuring Mitochondrial Function in Permeabilized Cells Using the Seahorse XF Analyzer or a Clark-Type Oxygen Electrode. Curr Protoc Toxicol. 2014 May 27; 60:25.2.1-16. PMID: 24865646.
        View in: PubMed
      20. Yamazaki KG, Andreyev AY, Ortiz-Vilchis P, Petrosyan S, Divakaruni AS, Wiley SE, De La Fuente C, Perkins G, Ceballos G, Villarreal F, Murphy A. Intravenous (-)-epicatechin reduces myocardial ischemic injury by protecting mitochondrial function. Int J Cardiol. 2014 Aug 01; 175(2):297-306. PMID: 24908200; PMCID: PMC4506135.
        View in: PubMed, PubMed Central
      21. Grassian AR, Parker SJ, Davidson SM, Divakaruni AS, Green CR, Zhang X, Slocum KL, Pu M, Lin F, Vickers C, Joud-Caldwell C, Chung F, Yin H, Handly ED, Straub C, Growney JD, Vander Heiden MG, Murphy A, Pagliarini R, Metallo CM. IDH1 mutations alter citric acid cycle metabolism and increase dependence on oxidative mitochondrial metabolism. Cancer Res. 2014 Jun 15; 74(12):3317-31. PMID: 24755473; PMCID: PMC4885639.
        View in: PubMed, PubMed Central
      22. Benincá C, Planagumà J, de Freitas Shuck A, Acín-Perez R, Muñoz JP, de Almeida MM, Brown JH, Murphy A, Zorzano A, Enríquez JA, Aragay AM. A new non-canonical pathway of Ga(q) protein regulating mitochondrial dynamics and bioenergetics. Cell Signal. 2014 May; 26(5):1135-46. PMID: 24444709; PMCID: PMC4745894.
        View in: PubMed, PubMed Central
      23. Divakaruni AS, Paradyse A, Ferrick DA, Murphy A, Jastroch M. Analysis and interpretation of microplate-based oxygen consumption and pH data. Methods Enzymol. 2014; 547:309-54. PMID: 25416364.
        View in: PubMed
      24. Murphy A, Chan DC. Methods in Enzymology. Mitochondrial function. Preface. Methods Enzymol. 2014; 547:xix-xx. PMID: 25416370.
        View in: PubMed
      25. Wiley SE, Andreyev AY, Divakaruni AS, Karisch R, Perkins G, Wall EA, van der Geer P, Chen YF, Tsai TF, Simon MI, Neel BG, Dixon JE, Murphy A. Wolfram Syndrome protein, Miner1, regulates sulphydryl redox status, the unfolded protein response, and Ca2+ homeostasis. EMBO Mol Med. 2013 Jun; 5(6):904-18. PMID: 23703906; PMCID: PMC3779451.
        View in: PubMed, PubMed Central
      26. Colca JR, McDonald WG, Cavey GS, Cole SL, Holewa DD, Brightwell-Conrad AS, Wolfe CL, Wheeler JS, Coulter KR, Kilkuskie PM, Gracheva E, Korshunova Y, Trusgnich M, Karr R, Wiley SE, Divakaruni AS, Murphy A, Vigueira PA, Finck BN, Kletzien RF. Identification of a mitochondrial target of thiazolidinedione insulin sensitizers (mTOT)--relationship to newly identified mitochondrial pyruvate carrier proteins. PLoS One. 2013; 8(5):e61551. PMID: 23690925; PMCID: PMC3655167.
        View in: PubMed, PubMed Central
      27. Divakaruni AS, Wiley SE, Rogers GW, Andreyev AY, Petrosyan S, Loviscach M, Wall EA, Yadava N, Heuck AP, Ferrick DA, Henry RR, McDonald WG, Colca JR, Simon MI, Ciaraldi TP, Murphy A. Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier. Proc Natl Acad Sci U S A. 2013 Apr 02; 110(14):5422-7. PMID: 23513224; PMCID: PMC3619368.
        View in: PubMed, PubMed Central
      28. Kubli DA, Zhang X, Lee Y, Hanna RA, Quinsay MN, Nguyen CK, Jimenez R, Petrosyan S, Murphy A, Gustafsson AB. Parkin protein deficiency exacerbates cardiac injury and reduces survival following myocardial infarction. J Biol Chem. 2013 Jan 11; 288(2):915-26. PMID: 23152496; PMCID: PMC3543040.
        View in: PubMed, PubMed Central
      29. Gibson CL, Murphy A, Murphy SP. Stroke outcome in the ketogenic state--a systematic review of the animal data. J Neurochem. 2012 Nov; 123 Suppl 2:52-7. PMID: 23050642; PMCID: PMC3970216.
        View in: PubMed, PubMed Central
      30. Darshi M, Trinh KN, Murphy A, Taylor SS. Targeting and import mechanism of coiled-coil helix coiled-coil helix domain-containing protein 3 (ChChd3) into the mitochondrial intermembrane space. J Biol Chem. 2012 Nov 16; 287(47):39480-91. PMID: 23019327; PMCID: PMC3501047.
        View in: PubMed, PubMed Central
      31. Wu-Zhang AX, Murphy A, Bachman M, Newton AC. Isozyme-specific interaction of protein kinase Cd with mitochondria dissected using live cell fluorescence imaging. J Biol Chem. 2012 Nov 02; 287(45):37891-906. PMID: 22988234; PMCID: PMC3488061.
        View in: PubMed, PubMed Central
      32. Divakaruni AS, Murphy A. Cell biology. A mitochondrial mystery, solved. Science. 2012 Jul 06; 337(6090):41-3. PMID: 22767917.
        View in: PubMed
      33. Da Cruz S, Parone PA, Lopes VS, Lillo C, McAlonis-Downes M, Lee SK, Vetto AP, Petrosyan S, Marsala M, Murphy A, Williams DS, Spiegelman BM, Cleveland DW. Elevated PGC-1a activity sustains mitochondrial biogenesis and muscle function without extending survival in a mouse model of inherited ALS. Cell Metab. 2012 May 02; 15(5):778-86. PMID: 22560226; PMCID: PMC3565468.
        View in: PubMed, PubMed Central
      34. Means CK, Lygren B, Langeberg LK, Jain A, Dixon RE, Vega AL, Gold MG, Petrosyan S, Taylor SS, Murphy A, Ha T, Santana LF, Tasken K, Scott JD. An entirely specific type I A-kinase anchoring protein that can sequester two molecules of protein kinase A at mitochondria. Proc Natl Acad Sci U S A. 2011 Nov 29; 108(48):E1227-35. PMID: 22084075; PMCID: PMC3228425.
        View in: PubMed, PubMed Central
      35. Taub PR, Ramirez-Sanchez I, Ciaraldi TP, Perkins G, Murphy A, Naviaux R, Hogan M, Maisel AS, Henry RR, Ceballos G, Villarreal F. Alterations in skeletal muscle indicators of mitochondrial structure and biogenesis in patients with type 2 diabetes and heart failure: effects of epicatechin rich cocoa. Clin Transl Sci. 2012 Feb; 5(1):43-7. PMID: 22376256.
        View in: PubMed
      36. Kawaraguchi Y, Horikawa YT, Murphy A, Murray F, Miyanohara A, Ali SS, Head BP, Patel PM, Roth DM, Patel HH. Volatile anesthetics protect cancer cells against tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis via caveolins. Anesthesiology. 2011 Sep; 115(3):499-508. PMID: 21862885; PMCID: PMC3162469.
        View in: PubMed, PubMed Central
      37. Rogers GW, Brand MD, Petrosyan S, Ashok D, Elorza AA, Ferrick DA, Murphy A. High throughput microplate respiratory measurements using minimal quantities of isolated mitochondria. PLoS One. 2011; 6(7):e21746. PMID: 21799747; PMCID: PMC3143121.
        View in: PubMed, PubMed Central
      38. Philp A, Chen A, Lan D, Meyer GA, Murphy A, Knapp AE, Olfert IM, McCurdy CE, Marcotte GR, Hogan MC, Baar K, Schenk S. Sirtuin 1 (SIRT1) deacetylase activity is not required for mitochondrial biogenesis or peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) deacetylation following endurance exercise. J Biol Chem. 2011 Sep 02; 286(35):30561-70. PMID: 21757760; PMCID: PMC3162416.
        View in: PubMed, PubMed Central
      39. Zhang J, Guan Z, Murphy A, Wiley SE, Perkins GA, Worby CA, Engel JL, Heacock P, Nguyen OK, Wang JH, Raetz CR, Dowhan W, Dixon JE. Mitochondrial phosphatase PTPMT1 is essential for cardiolipin biosynthesis. Cell Metab. 2011 Jun 08; 13(6):690-700. PMID: 21641550; PMCID: PMC3119201.
        View in: PubMed, PubMed Central
      40. Rikka S, Quinsay MN, Thomas RL, Kubli DA, Zhang X, Murphy A, Gustafsson ÅB. Bnip3 impairs mitochondrial bioenergetics and stimulates mitochondrial turnover. Cell Death Differ. 2011 Apr; 18(4):721-31. PMID: 21278801; PMCID: PMC3058880.
        View in: PubMed, PubMed Central
      41. Darshi M, Mendiola VL, Mackey MR, Murphy A, Koller A, Perkins GA, Ellisman MH, Taylor SS. ChChd3, an inner mitochondrial membrane protein, is essential for maintaining crista integrity and mitochondrial function. J Biol Chem. 2011 Jan 28; 286(4):2918-32. PMID: 21081504; PMCID: PMC3024787.
        View in: PubMed, PubMed Central
      42. Murphy SP, Murphy A. Pre-clinical systematic review. J Neurochem. 2010 Nov; 115(4):805. PMID: 21038509.
        View in: PubMed
      43. White AT, Murphy A. Administration of thiazolidinediones for neuroprotection in ischemic stroke: a pre-clinical systematic review. J Neurochem. 2010 Nov; 115(4):845-53. PMID: 20964688; PMCID: PMC2981074.
        View in: PubMed, PubMed Central
      44. Yeh TY, Beiswenger KK, Li P, Bolin KE, Lee RM, Tsao TS, Murphy A, Hevener AL, Chi NW. Hypermetabolism, hyperphagia, and reduced adiposity in tankyrase-deficient mice. Diabetes. 2009 Nov; 58(11):2476-85. PMID: 19651815; PMCID: PMC2768175.
        View in: PubMed, PubMed Central
      45. Murphy A. In a flurry of PINK, mitochondrial bioenergetics takes a leading role in Parkinson's disease. EMBO Mol Med. 2009 May; 1(2):81-4. PMID: 20049706; PMCID: PMC3378120.
        View in: PubMed, PubMed Central
      46. Miyamoto S, Murphy A, Brown JH. Akt mediated mitochondrial protection in the heart: metabolic and survival pathways to the rescue. J Bioenerg Biomembr. 2009 Apr; 41(2):169-80. PMID: 19377835; PMCID: PMC2732429.
        View in: PubMed, PubMed Central
      47. Rardin MJ, Wiley SE, Naviaux RK, Murphy A, Dixon JE. Monitoring phosphorylation of the pyruvate dehydrogenase complex. Anal Biochem. 2009 Jun 15; 389(2):157-64. PMID: 19341700; PMCID: PMC2713743.
        View in: PubMed, PubMed Central
      48. Murphy A, Allison WS. Mitochondrial function, part B: mitochondrial protein kinases, protein phosphatases and mitochondrial diseases. Preface. Methods Enzymol. 2009; 457:xxv-xxvi. PMID: 19426858.
        View in: PubMed
      49. Tang T, Zheng B, Chen SH, Murphy A, Kudlicka K, Zhou H, Farquhar MG. hNOA1 interacts with complex I and DAP3 and regulates mitochondrial respiration and apoptosis. J Biol Chem. 2009 Feb 20; 284(8):5414-24. PMID: 19103604; PMCID: PMC2643507.
        View in: PubMed, PubMed Central
      50. Rardin MJ, Wiley SE, Murphy A, Pagliarini DJ, Dixon JE. Dual specificity phosphatases 18 and 21 target to opposing sides of the mitochondrial inner membrane. J Biol Chem. 2008 May 30; 283(22):15440-50. PMID: 18385140; PMCID: PMC2397459.
        View in: PubMed, PubMed Central
      51. Miyamoto S, Murphy A, Brown JH. Akt mediates mitochondrial protection in cardiomyocytes through phosphorylation of mitochondrial hexokinase-II. Cell Death Differ. 2008 Mar; 15(3):521-9. PMID: 18064042.
        View in: PubMed
      52. Paddock ML, Wiley SE, Axelrod HL, Cohen AE, Roy M, Abresch EC, Capraro D, Murphy A, Nechushtai R, Dixon JE, Jennings PA. MitoNEET is a uniquely folded 2Fe 2S outer mitochondrial membrane protein stabilized by pioglitazone. Proc Natl Acad Sci U S A. 2007 Sep 04; 104(36):14342-7. PMID: 17766440; PMCID: PMC1963346.
        View in: PubMed, PubMed Central
      53. Wiley SE, Paddock ML, Abresch EC, Gross L, van der Geer P, Nechushtai R, Murphy A, Jennings PA, Dixon JE. The outer mitochondrial membrane protein mitoNEET contains a novel redox-active 2Fe-2S cluster. J Biol Chem. 2007 Aug 17; 282(33):23745-9. PMID: 17584744.
        View in: PubMed
      54. Wiley SE, Murphy A, Ross SA, van der Geer P, Dixon JE. MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity. Proc Natl Acad Sci U S A. 2007 Mar 27; 104(13):5318-23. PMID: 17376863; PMCID: PMC1838440.
        View in: PubMed, PubMed Central
      55. Yamaguchi R, Andreyev A, Murphy A, Perkins GA, Ellisman MH, Newmeyer DD. Mitochondria frozen with trehalose retain a number of biological functions and preserve outer membrane integrity. Cell Death Differ. 2007 Mar; 14(3):616-24. PMID: 16977331.
        View in: PubMed
      56. Lee J, Kim CH, Simon DK, Aminova LR, Andreyev AY, Kushnareva YE, Murphy A, Lonze BE, Kim KS, Ginty DD, Ferrante RJ, Ryu H, Ratan RR. Mitochondrial cyclic AMP response element-binding protein (CREB) mediates mitochondrial gene expression and neuronal survival. J Biol Chem. 2005 Dec 09; 280(49):40398-401. PMID: 16207717; PMCID: PMC2612541.
        View in: PubMed, PubMed Central
      57. Kushnareva YE, Wiley SE, Ward MW, Andreyev AY, Murphy A. Excitotoxic injury to mitochondria isolated from cultured neurons. J Biol Chem. 2005 Aug 12; 280(32):28894-902. PMID: 15932874.
        View in: PubMed
      58. Johnson K, Svensson CI, Etten DV, Ghosh SS, Murphy A, Powell HC, Terkeltaub R. Mediation of spontaneous knee osteoarthritis by progressive chondrocyte ATP depletion in Hartley guinea pigs. Arthritis Rheum. 2004 Apr; 50(4):1216-25. PMID: 15077304.
        View in: PubMed
      59. Taylor SW, Fahy E, Zhang B, Glenn GM, Warnock DE, Wiley S, Murphy A, Gaucher SP, Capaldi RA, Gibson BW, Ghosh SS. Characterization of the human heart mitochondrial proteome. Nat Biotechnol. 2003 Mar; 21(3):281-6. PMID: 12592411.
        View in: PubMed
      60. Kushnareva Y, Murphy A, Andreyev A. Complex I-mediated reactive oxygen species generation: modulation by cytochrome c and NAD(P)+ oxidation-reduction state. Biochem J. 2002 Dec 01; 368(Pt 2):545-53. PMID: 12180906; PMCID: PMC1222999.
        View in: PubMed, PubMed Central
      61. Fiskum G, Murphy A, Beal MF. Mitochondria in neurodegeneration: acute ischemia and chronic neurodegenerative diseases. J Cereb Blood Flow Metab. 1999 Apr; 19(4):351-69. PMID: 10197505.
        View in: PubMed
      62. Murphy A, Fiskum G, Beal MF. Mitochondria in neurodegeneration: bioenergetic function in cell life and death. J Cereb Blood Flow Metab. 1999 Mar; 19(3):231-45. PMID: 10078875.
        View in: PubMed
      63. Murphy A, Fiskum G. Bcl-2 and Ca(2+)-mediated mitochondrial dysfunction in neural cell death. Biochem Soc Symp. 1999; 66:33-41. PMID: 10989655.
        View in: PubMed
      64. Murphy A. Ca(2+)-mediated mitochondrial dysfunction and the protective effects of Bcl-2. Ann N Y Acad Sci. 1999; 893:19-32. PMID: 10672227.
        View in: PubMed
      65. Murphy A, Bredesen DE, Cortopassi G, Wang E, Fiskum G. Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria. Proc Natl Acad Sci U S A. 1996 Sep 3; 93(18):9893-8. PMID: 8790427.
        View in: PubMed
      66. Ellerby LM, Ellerby HM, Park SM, Holleran AL, Murphy A, Fiskum G, Kane DJ, Testa MP, Kayalar C, Bredesen DE. Shift of the cellular oxidation-reduction potential in neural cells expressing Bcl-2. J Neurochem. 1996 Sep; 67(3):1259-67. PMID: 8752134.
        View in: PubMed
      67. Myers KM, Fiskum G, Liu Y, Simmens SJ, Bredesen DE, Murphy A. Bcl-2 protects neural cells from cyanide/aglycemia-induced lipid oxidation, mitochondrial injury, and loss of viability. J Neurochem. 1995 Dec; 65(6):2432-40. PMID: 7595537.
        View in: PubMed
      68. Murphy A, Kelleher JK, Fiskum G. Submicromolar Ca2+ regulates phosphorylating respiration by normal rat liver and AS-30D hepatoma mitochondria by different mechanisms. J Biol Chem. 1990 Jun 25; 265(18):10527-34. PMID: 2113059.
        View in: PubMed
      69. Kelleher JK, Bryan BM, Mallet RT, Holleran AL, Murphy A, Fiskum G. Analysis of tricarboxylic acid-cycle metabolism of hepatoma cells by comparison of 14CO2 ratios. Biochem J. 1987 Sep 15; 246(3):633-9. PMID: 3120698; PMCID: PMC1148327.
        View in: PubMed, PubMed Central
      Anne's Networks
      Concepts
      Derived automatically from this person's publications.
      See all (432) concept(s)
      _
      Co-Authors
      People in Profiles who have published with this person.
      See all (47) people
      _
      Similar People
      People who share similar concepts with this person.
      See all (60) people
      _
      Same Department
      Search Department
      Physical Neighbors
      People whose addresses are nearby this person.
      _