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Anne Murphy

TitleAdjunct Professor
InstitutionUniversity of California San Diego
DepartmentPharmacology
Address9500 Gilman Drive #0636
La Jolla CA 92093
Phone858-246-0573
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    Collapse Biography 
    Collapse Education and Training
    George Washington UniversityPh.D.School of Medicine

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Metabolic role of the neuronal Na+-dependent citrate transporter implicated in epilepsy
    NIH/NINDS R21NS104513May 15, 2018 - Apr 30, 2020
    Role: Co-Principal Investigator
    Targeting the mitochondrial pyruvate carrier to treat neurodegenerative disease
    NIH/NINDS R01NS087611May 1, 2014 - Apr 30, 2019
    Role: Principal Investigator
    PPAR-sparing/free Thiazolidinediones for Treatment of Diabetes
    NIH/NIDDK R42DK081298May 1, 2009 - Mar 31, 2012
    Role: Principal Investigator
    OSTEOARTHRITIS/CHONDROCALCINOSIS: MITOCHONDRIAL THERAPY
    NIH/NIAMS R43AR049145Sep 24, 2003 - May 31, 2004
    Role: Principal Investigator
    PKA & PKC Targeting Mechanisms (Program Project)
    NIH/NIDDK P01DK054441Dec 15, 1998 - Mar 31, 2018
    Role: Co-Investigator
    BC1-2 IN HYPOXIA/REOXYGENATION
    NIH/NINDS R01NS034154Aug 10, 1996 - Apr 30, 2000
    Role: Principal Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Bustamante MF, Oliveira PG, Garcia-Carbonell R, Croft AP, Smith JM, Serrano RL, Sanchez-Lopez E, Liu X, Kisseleva T, Hay N, Buckley CD, Firestein GS, Murphy A, Miyamoto S, Guma M. Hexokinase 2 as a novel selective metabolic target for rheumatoid arthritis. Ann Rheum Dis. 2018 Jul 30. PMID: 30061164.
      View in: PubMed
    2. Raud B, Roy DG, Divakaruni AS, Tarasenko TN, Franke R, Ma EH, Samborska B, Hsieh WY, Wong AH, Stüve P, Arnold-Schrauf C, Guderian M, Lochner M, Rampertaap S, Romito K, Monsale J, Brönstrup M, Bensinger SJ, Murphy A, McGuire PJ, Jones RG, Sparwasser T, Berod L. Etomoxir Actions on Regulatory and Memory T Cells Are Independent of Cpt1a-Mediated Fatty Acid Oxidation. Cell Metab. 2018 Jun 19. PMID: 30043753.
      View in: PubMed
    3. Divakaruni AS, Hsieh WY, Minarrieta L, Duong TN, Kim KKO, Desousa BR, Andreyev AY, Bowman CE, Caradonna K, Dranka BP, Ferrick DA, Liesa M, Stiles L, Rogers GW, Braas D, Ciaraldi TP, Wolfgang MJ, Sparwasser T, Berod L, Bensinger SJ, Murphy A. Etomoxir Inhibits Macrophage Polarization by Disrupting CoA Homeostasis. Cell Metab. 2018 Jun 16. PMID: 30043752.
      View in: PubMed
    4. Falconer J, Murphy A, Young S, Clark AR, Tiziani S, Guma M, Buckley CD. Synovial cell metabolism and chronic inflammation in rheumatoid arthritis. Arthritis Rheumatol. 2018 Mar 26. PMID: 29579371.
      View in: PubMed
    5. Connolly NMC, Theurey P, Adam-Vizi V, Bazan NG, Bernardi P, Bolaños JP, Culmsee C, Dawson VL, Deshmukh M, Duchen MR, Düssmann H, Fiskum G, Galindo MF, Hardingham GE, Hardwick JM, Jekabsons MB, Jonas EA, Jordán J, Lipton SA, Manfredi G, Mattson MP, McLaughlin B, Methner A, Murphy A, Murphy MP, Nicholls DG, Polster BM, Pozzan T, Rizzuto R, Satrústegui J, Slack RS, Swanson RA, Swerdlow RH, Will Y, Ying Z, Joselin A, Gioran A, Moreira Pinho C, Watters O, Salvucci M, Llorente-Folch I, Park DS, Bano D, Ankarcrona M, Pizzo P, Prehn JHM. Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases. Cell Death Differ. 2018 Mar; 25(3):542-572. PMID: 29229998.
      View in: PubMed
    6. Barros LF, Bolaños JP, Bonvento G, Bouzier-Sore AK, Brown A, Hirrlinger J, Kasparov S, Kirchhoff F, Murphy A, Pellerin L, Robinson MB, Weber B. Current technical approaches to brain energy metabolism. Glia. 2018 Jun; 66(6):1138-1159. PMID: 29110344.
      View in: PubMed
    7. Divakaruni AS, Andreyev AY, Rogers GW, Murphy A. In situ measurements of mitochondrial matrix enzyme activities using plasma and mitochondrial membrane permeabilization agents. Anal Biochem. 2017 Oct 04. PMID: 28987935.
      View in: PubMed
    8. Orogo AM, Gonzalez ER, Kubli DA, Baptista IL, Ong SB, Prolla TA, Sussman MA, Murphy A, Gustafsson ÅB. Accumulation of mitochondrial DNA mutations disrupts cardiac progenitor cell function and reduces survival. J Biol Chem. 2017 07 07; 292(27):11348. PMID: 28687597.
      View in: PubMed
    9. Hashem SI, Murphy A, Divakaruni AS, Klos ML, Nelson BC, Gault EC, Rowland TJ, Perry CN, Gu Y, Dalton ND, Bradford WH, Devaney EJ, Peterson KL, Jones KL, Taylor MRG, Chen J, Chi NC, Adler ED. Impaired mitophagy facilitates mitochondrial damage in Danon disease. J Mol Cell Cardiol. 2017 Jul; 108:86-94. PMID: 28526246.
      View in: PubMed
    10. Divakaruni AS, Wallace M, Buren C, Martyniuk K, Andreyev AY, Li E, Fields JA, Cordes T, Reynolds IJ, Bloodgood BL, Raymond LA, Metallo CM, Murphy A. Inhibition of the mitochondrial pyruvate carrier protects from excitotoxic neuronal death. J Cell Biol. 2017 04 03; 216(4):1091-1105. PMID: 28254829.
      View in: PubMed
    11. Parker SJ, Svensson RU, Divakaruni AS, Lefebvre AE, Murphy A, Shaw RJ, Metallo CM. LKB1 promotes metabolic flexibility in response to energy stress. Metab Eng. 2017 Sep; 43(Pt B):208-217. PMID: 28034771.
      View in: PubMed
    12. Zhang H, Badur MG, Divakaruni AS, Parker SJ, Jäger C, Hiller K, Murphy A, Metallo CM. Distinct Metabolic States Can Support Self-Renewal and Lipogenesis in Human Pluripotent Stem Cells under Different Culture Conditions. Cell Rep. 2016 08 09; 16(6):1536-1547. PMID: 27477285; PMCID: PMC4981511.
      View in: PubMed, PubMed Central
    13. Garcia-Carbonell R, Divakaruni AS, Lodi A, Vicente-Suarez I, Saha A, Cheroutre H, Boss GR, Tiziani S, Murphy A, Guma M. Critical Role of Glucose Metabolism in Rheumatoid Arthritis Fibroblast-like Synoviocytes. Arthritis Rheumatol. 2016 07; 68(7):1614-26. PMID: 26815411; PMCID: PMC4963240.
      View in: PubMed, PubMed Central
    14. Cordes T, Wallace M, Michelucci A, Divakaruni AS, Sapcariu SC, Sousa C, Koseki H, Cabrales P, Murphy A, Hiller K, Metallo CM. Immunoresponsive Gene 1 and Itaconate Inhibit Succinate Dehydrogenase to Modulate Intracellular Succinate Levels. J Biol Chem. 2016 Jul 01; 291(27):14274-84. PMID: 27189937; PMCID: PMC4933182 [Available on 07/01/17].
      View in: PubMed, PubMed Central
    15. Ding B, Parmigiani A, Divakaruni AS, Archer K, Murphy A, Budanov AV. Sestrin2 is induced by glucose starvation via the unfolded protein response and protects cells from non-canonical necroptotic cell death. Sci Rep. 2016 Mar 02; 6:22538. PMID: 26932729; PMCID: PMC4773760.
      View in: PubMed, PubMed Central
    16. Fields JA, Serger E, Campos S, Divakaruni AS, Kim C, Smith K, Trejo M, Adame A, Spencer B, Rockenstein E, Murphy A, Ellis RJ, Letendre S, Grant I, Masliah E. HIV alters neuronal mitochondrial fission/fusion in the brain during HIV-associated neurocognitive disorders. Neurobiol Dis. 2016 Feb; 86:154-69. PMID: 26611103; PMCID: PMC4713337.
      View in: PubMed, PubMed Central
    17. Green CR, Wallace M, Divakaruni AS, Phillips SA, Murphy A, Ciaraldi TP, Metallo CM. Branched-chain amino acid catabolism fuels adipocyte differentiation and lipogenesis. Nat Chem Biol. 2016 Jan; 12(1):15-21. PMID: 26571352; PMCID: PMC4684771.
      View in: PubMed, PubMed Central
    18. Giacco F, Du X, Carratú A, Gerfen GJ, D'Apolito M, Giardino I, Rasola A, Marin O, Divakaruni AS, Murphy A, Shah MS, Brownlee M. GLP-1 Cleavage Product Reverses Persistent ROS Generation After Transient Hyperglycemia by Disrupting an ROS-Generating Feedback Loop. Diabetes. 2015 Sep; 64(9):3273-84. PMID: 26294429; PMCID: PMC4542449.
      View in: PubMed, PubMed Central
    19. Wilderman A, Guo Y, Divakaruni AS, Perkins G, Zhang L, Murphy A, Taylor SS, Insel PA. Proteomic and Metabolic Analyses of S49 Lymphoma Cells Reveal Novel Regulation of Mitochondria by cAMP and Protein Kinase A. J Biol Chem. 2015 Sep 04; 290(36):22274-86. PMID: 26203188; PMCID: PMC4571978.
      View in: PubMed, PubMed Central
    20. Orogo AM, Gonzalez ER, Kubli DA, Baptista IL, Ong SB, Prolla TA, Sussman MA, Murphy A, Gustafsson ÅB. Accumulation of Mitochondrial DNA Mutations Disrupts Cardiac Progenitor Cell Function and Reduces Survival. J Biol Chem. 2015 Sep 04; 290(36):22061-75. PMID: 26183775; PMCID: PMC4571958.
      View in: PubMed, PubMed Central
    21. Westenbrink BD, Ling H, Divakaruni AS, Gray CB, Zambon AC, Dalton ND, Peterson KL, Gu Y, Matkovich SJ, Murphy A, Miyamoto S, Dorn GW, Heller Brown J. Mitochondrial reprogramming induced by CaMKIId mediates hypertrophy decompensation. Circ Res. 2015 Feb 27; 116(5):e28-39. PMID: 25605649; PMCID: PMC4344921.
      View in: PubMed, PubMed Central
    22. Andreyev AY, Tsui HS, Milne GL, Shmanai VV, Bekish AV, Fomich MA, Pham MN, Nong Y, Murphy A, Clarke CF, Shchepinov MS. Isotope-reinforced polyunsaturated fatty acids protect mitochondria from oxidative stress. Free Radic Biol Med. 2015 May; 82:63-72. PMID: 25578654.
      View in: PubMed
    23. Vacanti NM, Divakaruni AS, Green CR, Parker SJ, Henry RR, Ciaraldi TP, Murphy A, Metallo CM. Regulation of substrate utilization by the mitochondrial pyruvate carrier. Mol Cell. 2014 Nov 06; 56(3):425-35. PMID: 25458843; PMCID: PMC4267523.
      View in: PubMed, PubMed Central
    24. White AT, Philp A, Fridolfsson HN, Schilling JM, Murphy A, Hamilton DL, McCurdy CE, Patel HH, Schenk S. High-fat diet-induced impairment of skeletal muscle insulin sensitivity is not prevented by SIRT1 overexpression. Am J Physiol Endocrinol Metab. 2014 Nov 01; 307(9):E764-72. PMID: 25159328; PMCID: PMC4216952.
      View in: PubMed, PubMed Central
    25. Divakaruni AS, Rogers GW, Murphy A. Measuring Mitochondrial Function in Permeabilized Cells Using the Seahorse XF Analyzer or a Clark-Type Oxygen Electrode. Curr Protoc Toxicol. 2014 May 27; 60:25.2.1-16. PMID: 24865646.
      View in: PubMed
    26. Yamazaki KG, Andreyev AY, Ortiz-Vilchis P, Petrosyan S, Divakaruni AS, Wiley SE, De La Fuente C, Perkins G, Ceballos G, Villarreal F, Murphy A. Intravenous (-)-epicatechin reduces myocardial ischemic injury by protecting mitochondrial function. Int J Cardiol. 2014 Aug 01; 175(2):297-306. PMID: 24908200; PMCID: PMC4506135.
      View in: PubMed, PubMed Central
    27. Grassian AR, Parker SJ, Davidson SM, Divakaruni AS, Green CR, Zhang X, Slocum KL, Pu M, Lin F, Vickers C, Joud-Caldwell C, Chung F, Yin H, Handly ED, Straub C, Growney JD, Vander Heiden MG, Murphy A, Pagliarini R, Metallo CM. IDH1 mutations alter citric acid cycle metabolism and increase dependence on oxidative mitochondrial metabolism. Cancer Res. 2014 Jun 15; 74(12):3317-31. PMID: 24755473; PMCID: PMC4885639.
      View in: PubMed, PubMed Central
    28. Benincá C, Planagumà J, de Freitas Shuck A, Acín-Perez R, Muñoz JP, de Almeida MM, Brown JH, Murphy A, Zorzano A, Enríquez JA, Aragay AM. A new non-canonical pathway of Ga(q) protein regulating mitochondrial dynamics and bioenergetics. Cell Signal. 2014 May; 26(5):1135-46. PMID: 24444709; PMCID: PMC4745894.
      View in: PubMed, PubMed Central
    29. Divakaruni AS, Paradyse A, Ferrick DA, Murphy A, Jastroch M. Analysis and interpretation of microplate-based oxygen consumption and pH data. Methods Enzymol. 2014; 547:309-54. PMID: 25416364.
      View in: PubMed
    30. Murphy A, Chan DC. Methods in Enzymology. Mitochondrial function. Preface. Methods Enzymol. 2014; 547:xix-xx. PMID: 25416370.
      View in: PubMed
    31. Wiley SE, Andreyev AY, Divakaruni AS, Karisch R, Perkins G, Wall EA, van der Geer P, Chen YF, Tsai TF, Simon MI, Neel BG, Dixon JE, Murphy A. Wolfram Syndrome protein, Miner1, regulates sulphydryl redox status, the unfolded protein response, and Ca2+ homeostasis. EMBO Mol Med. 2013 Jun; 5(6):904-18. PMID: 23703906; PMCID: PMC3779451.
      View in: PubMed, PubMed Central
    32. Colca JR, McDonald WG, Cavey GS, Cole SL, Holewa DD, Brightwell-Conrad AS, Wolfe CL, Wheeler JS, Coulter KR, Kilkuskie PM, Gracheva E, Korshunova Y, Trusgnich M, Karr R, Wiley SE, Divakaruni AS, Murphy A, Vigueira PA, Finck BN, Kletzien RF. Identification of a mitochondrial target of thiazolidinedione insulin sensitizers (mTOT)--relationship to newly identified mitochondrial pyruvate carrier proteins. PLoS One. 2013; 8(5):e61551. PMID: 23690925; PMCID: PMC3655167.
      View in: PubMed, PubMed Central
    33. Divakaruni AS, Wiley SE, Rogers GW, Andreyev AY, Petrosyan S, Loviscach M, Wall EA, Yadava N, Heuck AP, Ferrick DA, Henry RR, McDonald WG, Colca JR, Simon MI, Ciaraldi TP, Murphy A. Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier. Proc Natl Acad Sci U S A. 2013 Apr 02; 110(14):5422-7. PMID: 23513224; PMCID: PMC3619368.
      View in: PubMed, PubMed Central
    34. Kubli DA, Zhang X, Lee Y, Hanna RA, Quinsay MN, Nguyen CK, Jimenez R, Petrosyan S, Murphy A, Gustafsson AB. Parkin protein deficiency exacerbates cardiac injury and reduces survival following myocardial infarction. J Biol Chem. 2013 Jan 11; 288(2):915-26. PMID: 23152496; PMCID: PMC3543040.
      View in: PubMed, PubMed Central
    35. Gibson CL, Murphy A, Murphy SP. Stroke outcome in the ketogenic state--a systematic review of the animal data. J Neurochem. 2012 Nov; 123 Suppl 2:52-7. PMID: 23050642; PMCID: PMC3970216.
      View in: PubMed, PubMed Central
    36. Darshi M, Trinh KN, Murphy A, Taylor SS. Targeting and import mechanism of coiled-coil helix coiled-coil helix domain-containing protein 3 (ChChd3) into the mitochondrial intermembrane space. J Biol Chem. 2012 Nov 16; 287(47):39480-91. PMID: 23019327; PMCID: PMC3501047.
      View in: PubMed, PubMed Central
    37. Wu-Zhang AX, Murphy A, Bachman M, Newton AC. Isozyme-specific interaction of protein kinase Cd with mitochondria dissected using live cell fluorescence imaging. J Biol Chem. 2012 Nov 02; 287(45):37891-906. PMID: 22988234; PMCID: PMC3488061.
      View in: PubMed, PubMed Central
    38. Divakaruni AS, Murphy A. Cell biology. A mitochondrial mystery, solved. Science. 2012 Jul 06; 337(6090):41-3. PMID: 22767917.
      View in: PubMed
    39. Da Cruz S, Parone PA, Lopes VS, Lillo C, McAlonis-Downes M, Lee SK, Vetto AP, Petrosyan S, Marsala M, Murphy A, Williams DS, Spiegelman BM, Cleveland DW. Elevated PGC-1a activity sustains mitochondrial biogenesis and muscle function without extending survival in a mouse model of inherited ALS. Cell Metab. 2012 May 02; 15(5):778-86. PMID: 22560226.
      View in: PubMed
    40. Means CK, Lygren B, Langeberg LK, Jain A, Dixon RE, Vega AL, Gold MG, Petrosyan S, Taylor SS, Murphy A, Ha T, Santana LF, Tasken K, Scott JD. An entirely specific type I A-kinase anchoring protein that can sequester two molecules of protein kinase A at mitochondria. Proc Natl Acad Sci U S A. 2011 Nov 29; 108(48):E1227-35. PMID: 22084075; PMCID: PMC3228425.
      View in: PubMed, PubMed Central
    41. Taub PR, Ramirez-Sanchez I, Ciaraldi TP, Perkins G, Murphy A, Naviaux R, Hogan M, Maisel AS, Henry RR, Ceballos G, Villarreal F. Alterations in skeletal muscle indicators of mitochondrial structure and biogenesis in patients with type 2 diabetes and heart failure: effects of epicatechin rich cocoa. Clin Transl Sci. 2012 Feb; 5(1):43-7. PMID: 22376256.
      View in: PubMed
    42. Kawaraguchi Y, Horikawa YT, Murphy A, Murray F, Miyanohara A, Ali SS, Head BP, Patel PM, Roth DM, Patel HH. Volatile anesthetics protect cancer cells against tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis via caveolins. Anesthesiology. 2011 Sep; 115(3):499-508. PMID: 21862885; PMCID: PMC3162469.
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    43. Rogers GW, Brand MD, Petrosyan S, Ashok D, Elorza AA, Ferrick DA, Murphy A. High throughput microplate respiratory measurements using minimal quantities of isolated mitochondria. PLoS One. 2011; 6(7):e21746. PMID: 21799747; PMCID: PMC3143121.
      View in: PubMed, PubMed Central
    44. Philp A, Chen A, Lan D, Meyer GA, Murphy A, Knapp AE, Olfert IM, McCurdy CE, Marcotte GR, Hogan MC, Baar K, Schenk S. Sirtuin 1 (SIRT1) deacetylase activity is not required for mitochondrial biogenesis or peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) deacetylation following endurance exercise. J Biol Chem. 2011 Sep 02; 286(35):30561-70. PMID: 21757760; PMCID: PMC3162416.
      View in: PubMed, PubMed Central
    45. Zhang J, Guan Z, Murphy A, Wiley SE, Perkins GA, Worby CA, Engel JL, Heacock P, Nguyen OK, Wang JH, Raetz CR, Dowhan W, Dixon JE. Mitochondrial phosphatase PTPMT1 is essential for cardiolipin biosynthesis. Cell Metab. 2011 Jun 08; 13(6):690-700. PMID: 21641550; PMCID: PMC3119201.
      View in: PubMed, PubMed Central
    46. Darshi M, Mendiola VL, Mackey MR, Murphy A, Koller A, Perkins GA, Ellisman MH, Taylor SS. ChChd3, an inner mitochondrial membrane protein, is essential for maintaining crista integrity and mitochondrial function. J Biol Chem. 2011 Jan 28; 286(4):2918-32. PMID: 21081504; PMCID: PMC3024787.
      View in: PubMed, PubMed Central
    47. Murphy SP, Murphy A. Pre-clinical systematic review. J Neurochem. 2010 Nov; 115(4):805. PMID: 21038509.
      View in: PubMed
    48. White AT, Murphy A. Administration of thiazolidinediones for neuroprotection in ischemic stroke: a pre-clinical systematic review. J Neurochem. 2010 Nov; 115(4):845-53. PMID: 20964688; PMCID: PMC2981074.
      View in: PubMed, PubMed Central
    49. Yeh TY, Beiswenger KK, Li P, Bolin KE, Lee RM, Tsao TS, Murphy A, Hevener AL, Chi NW. Hypermetabolism, hyperphagia, and reduced adiposity in tankyrase-deficient mice. Diabetes. 2009 Nov; 58(11):2476-85. PMID: 19651815; PMCID: PMC2768175.
      View in: PubMed, PubMed Central
    50. Murphy A. In a flurry of PINK, mitochondrial bioenergetics takes a leading role in Parkinson's disease. EMBO Mol Med. 2009 May; 1(2):81-4. PMID: 20049706; PMCID: PMC3378120.
      View in: PubMed, PubMed Central
    51. Miyamoto S, Murphy A, Brown JH. Akt mediated mitochondrial protection in the heart: metabolic and survival pathways to the rescue. J Bioenerg Biomembr. 2009 Apr; 41(2):169-80. PMID: 19377835; PMCID: PMC2732429.
      View in: PubMed, PubMed Central
    52. Rardin MJ, Wiley SE, Naviaux RK, Murphy A, Dixon JE. Monitoring phosphorylation of the pyruvate dehydrogenase complex. Anal Biochem. 2009 Jun 15; 389(2):157-64. PMID: 19341700; PMCID: PMC2713743.
      View in: PubMed, PubMed Central
    53. Murphy A, Allison WS. Mitochondrial function, part B: mitochondrial protein kinases, protein phosphatases and mitochondrial diseases. Preface. Methods Enzymol. 2009; 457:xxv-xxvi. PMID: 19426858.
      View in: PubMed
    54. Tang T, Zheng B, Chen SH, Murphy A, Kudlicka K, Zhou H, Farquhar MG. hNOA1 interacts with complex I and DAP3 and regulates mitochondrial respiration and apoptosis. J Biol Chem. 2009 Feb 20; 284(8):5414-24. PMID: 19103604; PMCID: PMC2643507.
      View in: PubMed, PubMed Central
    55. Rardin MJ, Wiley SE, Murphy A, Pagliarini DJ, Dixon JE. Dual specificity phosphatases 18 and 21 target to opposing sides of the mitochondrial inner membrane. J Biol Chem. 2008 May 30; 283(22):15440-50. PMID: 18385140; PMCID: PMC2397459.
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    56. Paddock ML, Wiley SE, Axelrod HL, Cohen AE, Roy M, Abresch EC, Capraro D, Murphy A, Nechushtai R, Dixon JE, Jennings PA. MitoNEET is a uniquely folded 2Fe 2S outer mitochondrial membrane protein stabilized by pioglitazone. Proc Natl Acad Sci U S A. 2007 Sep 04; 104(36):14342-7. PMID: 17766440; PMCID: PMC1963346.
      View in: PubMed, PubMed Central
    57. Wiley SE, Paddock ML, Abresch EC, Gross L, van der Geer P, Nechushtai R, Murphy A, Jennings PA, Dixon JE. The outer mitochondrial membrane protein mitoNEET contains a novel redox-active 2Fe-2S cluster. J Biol Chem. 2007 Aug 17; 282(33):23745-9. PMID: 17584744.
      View in: PubMed
    58. Wiley SE, Murphy A, Ross SA, van der Geer P, Dixon JE. MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity. Proc Natl Acad Sci U S A. 2007 Mar 27; 104(13):5318-23. PMID: 17376863; PMCID: PMC1838440.
      View in: PubMed, PubMed Central
    59. Lee J, Kim CH, Simon DK, Aminova LR, Andreyev AY, Kushnareva YE, Murphy A, Lonze BE, Kim KS, Ginty DD, Ferrante RJ, Ryu H, Ratan RR. Mitochondrial cyclic AMP response element-binding protein (CREB) mediates mitochondrial gene expression and neuronal survival. J Biol Chem. 2005 Dec 09; 280(49):40398-401. PMID: 16207717; PMCID: PMC2612541.
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    60. Kushnareva YE, Wiley SE, Ward MW, Andreyev AY, Murphy A. Excitotoxic injury to mitochondria isolated from cultured neurons. J Biol Chem. 2005 Aug 12; 280(32):28894-902. PMID: 15932874.
      View in: PubMed
    61. Johnson K, Svensson CI, Etten DV, Ghosh SS, Murphy A, Powell HC, Terkeltaub R. Mediation of spontaneous knee osteoarthritis by progressive chondrocyte ATP depletion in Hartley guinea pigs. Arthritis Rheum. 2004 Apr; 50(4):1216-25. PMID: 15077304.
      View in: PubMed
    62. Taylor SW, Fahy E, Zhang B, Glenn GM, Warnock DE, Wiley S, Murphy A, Gaucher SP, Capaldi RA, Gibson BW, Ghosh SS. Characterization of the human heart mitochondrial proteome. Nat Biotechnol. 2003 Mar; 21(3):281-6. PMID: 12592411.
      View in: PubMed
    63. Kushnareva Y, Murphy A, Andreyev A. Complex I-mediated reactive oxygen species generation: modulation by cytochrome c and NAD(P)+ oxidation-reduction state. Biochem J. 2002 Dec 01; 368(Pt 2):545-53. PMID: 12180906; PMCID: PMC1222999.
      View in: PubMed, PubMed Central
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