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Biomolecular Condensates in and Around the ER-Golgi Interface. Subcell Biochem. 2026; 110:221-243.
Ruiz M, Bogus SM, Ernst AM. PMID: 41240313.
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1 Fields:
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HumansAnimalsCells
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Mechanistic insights into cargo sorting and export from the Golgi apparatus. Nat Rev Mol Cell Biol. 2025 Dec; 26(12):940-956.
Watson ET, Wegeng WR, Aravani S, Ernst AM, von Blume J. PMID: 41214333.
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HumansAnimalsCells
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Cell fate ratios are encoded by transcriptional dynamics in the Drosophila retina. Curr Biol. 2025 Jun 23; 35(12):2946-2959.e5.
Ainsworth J, Zhao Y, Gao K, Gravina NM, Goldberg ZH, Pinkerton C, Rifkin SA, Ernst AM, Garcia HG, Perry MW. PMID: 40499552; PMCID: PMC12208096.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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A hollow TFG condensate spatially compartmentalizes the early secretory pathway. Nat Commun. 2025 Apr 19; 16(1):3715.
Bogus SM, Wegeng WR, Ruiz M, Chavez SR, Cheung SN, Noori KSM, Niesman IR, Ernst AM. PMID: 40253417; PMCID: PMC12009431.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Exploitation of the fibrinolytic system by B-cell acute lymphoblastic leukemia and its therapeutic targeting. Nat Commun. 2024 11 20; 15(1):10059.
Minciacchi VR, Bravo J, Karantanou C, Pereira RS, Zanetti C, Kumar R, Thomasberger N, Llavona P, Krack T, Bankov K, Meister M, Hartmann S, Maguer-Satta V, Lefort S, Putyrski M, Ernst A, Huntly BJP, Meduri E, Ruf W, Krause DS. PMID: 39567540; PMCID: PMC11579293.
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PubMed Mentions:
3 Fields:
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HumansAnimalsCells
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C. elegans epicuticlins define specific compartments in the apical extracellular matrix and function in wound repair. Development. 2024 Nov 01; 151(21).
Pooranachithra M, Jyo EM, Brouilly N, Pujol N, Ernst AM, Chisholm AD. PMID: 39373389; PMCID: PMC11529277.
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PubMed Mentions:
4 Fields:
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AnimalsCells
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Biallelic NAA60 variants with impaired n-terminal acetylation capacity cause autosomal recessive primary familial brain calcifications. Nat Commun. 2024 Mar 13; 15(1):2269.
Chelban V, Aksnes H, Maroofian R, LaMonica LC, Seabra L, Siggervåg A, Devic P, Shamseldin HE, Vandrovcova J, Murphy D, Richard AC, Quenez O, Bonnevalle A, Zanetti MN, Kaiyrzhanov R, Salpietro V, Efthymiou S, Schottlaender LV, Morsy H, Scardamaglia A, Tariq A, Pagnamenta AT, Pennavaria A, Krogstad LS, Bekkelund ÅK, Caiella A, Glomnes N, Brønstad KM, Tury S, Moreno De Luca A, Boland-Auge A, Olaso R, Deleuze JF, Anheim M, Cretin B, Vona B, Alajlan F, Abdulwahab F, Battini JL, Ipek R, Bauer P, Zifarelli G, Gungor S, Kurul SH, Lochmuller H, Da'as SI, Fakhro KA, Gómez-Pascual A, Botía JA, Wood NW, Horvath R, Ernst AM, Rothman JE, McEntagart M, Crow YJ, Alkuraya FS, Nicolas G, SYNaPS Study Group, Arnesen T, Houlden H. PMID: 38480682; PMCID: PMC10937998.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells
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C. elegans epicuticlins define specific compartments in the apical extracellular matrix and function in wound repair. bioRxiv. 2024 Jan 30.
Pooranachithra M, Jyo EM, Ernst AM, Chisholm AD. PMID: 38260454; PMCID: PMC10802564.
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Exome-informed formulations of food proteins enhance body growth and feed conversion efficiency in ad libitum-fed mice. Food Res Int. 2024 Jan; 176:113819.
Wu T, Baatar D, O' Connor AE, O'Bryan MK, Stringer JM, Hutt KJ, Malimige Aponso M, Monro K, Luo J, Zhu Y, Ernst A, Swindells EOK, Alesi LR, Tho Tony Nguyen N, Piper MDW, Bennett LE. PMID: 38163720.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Nanoscale patterning of collagens in C. elegans apical extracellular matrix. Nat Commun. 2023 11 18; 14(1):7506.
Adams JRG, Pooranachithra M, Jyo EM, Zheng SL, Goncharov A, Crew JR, Kramer JM, Jin Y, Ernst AM, Chisholm AD. PMID: 37980413; PMCID: PMC10657453.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Roles for diacylglycerol in synaptic vesicle priming and release revealed by complete reconstitution of core protein machinery. Proc Natl Acad Sci U S A. 2023 08 22; 120(34):e2309516120.
Kalyana Sundaram RV, Chatterjee A, Bera M, Grushin K, Panda A, Li F, Coleman J, Lee S, Ramakrishnan S, Ernst AM, Gupta K, Rothman JE, Krishnakumar SS. PMID: 37590407; PMCID: PMC10450444.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Novel Roles for Diacylglycerol in Synaptic Vesicle Priming and Release Revealed by Complete Reconstitution of Core Protein Machinery. bioRxiv. 2023 Jun 07.
Sundaram RVK, Chatterjee A, Bera M, Grushin K, Panda A, Li F, Coleman J, Lee S, Ramakrishnan S, Ernst AM, Gupta K, Rothman JE, Krishnakumar SS. PMID: 37333317; PMCID: PMC10274626.
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Intrauterine Exposure to Acetaminophen and Adverse Developmental Outcomes: Epidemiological Findings and Methodological Issues. Curr Environ Health Rep. 2021 03; 8(1):23-33.
Liew Z, Ernst A. PMID: 33398668.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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The golgin family exhibits a propensity to form condensates in living cells. FEBS Lett. 2020 10; 594(19):3086-3094.
Ziltener P, Rebane AA, Graham M, Ernst AM, Rothman JE. PMID: 32668013; PMCID: PMC7589415.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Discovery of Protein-Protein Interaction Inhibitors by Integrating Protein Engineering and Chemical Screening Platforms. Cell Chem Biol. 2020 11 19; 27(11):1441-1451.e7.
Maculins T, Garcia-Pardo J, Skenderovic A, Gebel J, Putyrski M, Vorobyov A, Busse P, Varga G, Kuzikov M, Zaliani A, Rahighi S, Schaeffer V, Parnham MJ, Sidhu SS, Ernst A, Dötsch V, Akutsu M, Dikic I. PMID: 32726587.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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TANGO1 membrane helices create a lipid diffusion barrier at curved membranes. Elife. 2020 05 26; 9.
Raote I, Ernst AM, Campelo F, Rothman JE, Pincet F, Malhotra V. PMID: 32452385; PMCID: PMC7266638.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Palmitoylated Proteins in Plasmodium falciparum-Infected Erythrocytes: Investigation with Click Chemistry and Metabolic Labeling. Bioessays. 2020 06; 42(6):e1900145.
Kilian N, Zhang Y, LaMonica L, Hooker G, Toomre D, Mamoun CB, Ernst AM. PMID: 32342554.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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Disrupting the LC3 Interaction Region (LIR) Binding of Selective Autophagy Receptors Sensitizes AML Cell Lines to Cytarabine. Front Cell Dev Biol. 2020; 8:208.
Putyrski M, Vakhrusheva O, Bonn F, Guntur S, Vorobyov A, Brandts C, Dikic I, Ernst A. PMID: 32296703; PMCID: PMC7137635.
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PubMed Mentions:
17
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Conformation-specific inhibitors of activated Ras GTPases reveal limited Ras dependency of patient-derived cancer organoids. J Biol Chem. 2020 04 03; 295(14):4526-4540.
Wiechmann S, Maisonneuve P, Grebbin BM, Hoffmeister M, Kaulich M, Clevers H, Rajalingam K, Kurinov I, Farin HF, Sicheri F, Ernst A. PMID: 32086379; PMCID: PMC7136003.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Liquid-liquid phase separation of the Golgi matrix protein GM130. FEBS Lett. 2020 04; 594(7):1132-1144.
Rebane AA, Ziltener P, LaMonica LC, Bauer AH, Zheng H, López-Montero I, Pincet F, Rothman JE, Ernst AM. PMID: 31833055; PMCID: PMC7160038.
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PubMed Mentions:
40 Fields:
Translation:
HumansCells
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Acylation - A New Means to Control Traffic Through the Golgi. Front Cell Dev Biol. 2019; 7:109.
Ernst AM, Toomre D, Bogan JS. PMID: 31245373; PMCID: PMC6582194.
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PubMed Mentions:
16
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IL-38 Ameliorates Skin Inflammation and Limits IL-17 Production from γδ T Cells. Cell Rep. 2019 04 16; 27(3):835-846.e5.
Han Y, Mora J, Huard A, da Silva P, Wiechmann S, Putyrski M, Schuster C, Elwakeel E, Lang G, Scholz A, Scholz T, Schmid T, de Bruin N, Billuart P, Sala C, Burkhardt H, Parnham MJ, Ernst A, Brüne B, Weigert A. PMID: 30995480.
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PubMed Mentions:
57 Fields:
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HumansAnimalsCells
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Circular synthesized CRISPR/Cas gRNAs for functional interrogations in the coding and noncoding genome. Elife. 2019 Mar 06; 8.
Wegner M, Diehl V, Bittl V, de Bruyn R, Wiechmann S, Matthess Y, Hebel M, Hayes MG, Schaubeck S, Benner C, Heinz S, Bremm A, Dikic I, Ernst A, Kaulich M. PMID: 30838976; PMCID: PMC6424562.
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PubMed Mentions:
20 Fields:
Translation:
HumansCells
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Exposure to Perfluoroalkyl Substances during Fetal Life and Pubertal Development in Boys and Girls from the Danish National Birth Cohort. Environ Health Perspect. 2019 01; 127(1):17004.
Ernst A, Brix N, Lauridsen LLB, Olsen J, Parner ET, Liew Z, Olsen LH, Ramlau-Hansen CH. PMID: 30628845; PMCID: PMC6378681.
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PubMed Mentions:
37 Fields:
Translation:
HumansPHPublic Health
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S-Palmitoylation Sorts Membrane Cargo for Anterograde Transport in the Golgi. Dev Cell. 2018 11 19; 47(4):479-493.e7.
Ernst AM, Syed SA, Zaki O, Bottanelli F, Zheng H, Hacke M, Xi Z, Rivera-Molina F, Graham M, Rebane AA, Björkholm P, Baddeley D, Toomre D, Pincet F, Rothman JE. PMID: 30458139; PMCID: PMC6251505.
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PubMed Mentions:
83 Fields:
Translation:
HumansCells
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Land-locked mammalian Golgi reveals cargo transport between stable cisternae. Nat Commun. 2017 09 05; 8(1):432.
Dunlop MH, Ernst AM, Schroeder LK, Toomre DK, Lavieu G, Rothman JE. PMID: 28874656; PMCID: PMC5585379.
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PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCells
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Site-specific inhibition of the small ubiquitin-like modifier (SUMO)-conjugating enzyme Ubc9 selectively impairs SUMO chain formation. J Biol Chem. 2017 09 15; 292(37):15340-15351.
Wiechmann S, Gärtner A, Kniss A, Stengl A, Behrends C, Rogov VV, Rodriguez MS, Dötsch V, Müller S, Ernst A. PMID: 28784659; PMCID: PMC5602394.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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A novel physiological role for ARF1 in the formation of bidirectional tubules from the Golgi. Mol Biol Cell. 2017 Jun 15; 28(12):1676-1687.
Bottanelli F, Kilian N, Ernst AM, Rivera-Molina F, Schroeder LK, Kromann EB, Lessard MD, Erdmann RS, Schepartz A, Baddeley D, Bewersdorf J, Toomre D, Rothman JE. PMID: 28428254; PMCID: PMC5469610.
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PubMed Mentions:
46 Fields:
Translation:
HumansCells
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Fluorescence-based ATG8 sensors monitor localization and function of LC3/GABARAP proteins. EMBO J. 2017 02 15; 36(4):549-564.
Stolz A, Putyrski M, Kutle I, Huber J, Wang C, Major V, Sidhu SS, Youle RJ, Rogov VV, Dötsch V, Ernst A, Dikic I. PMID: 28028054; PMCID: PMC5437816.
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PubMed Mentions:
31 Fields:
Translation:
HumansCells
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Why mitochondria need a genome revisited. FEBS Lett. 2017 Jan; 591(1):65-75.
Björkholm P, Ernst AM, Hagström E, Andersson SG. PMID: 27928819.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Interleukin-38 is released from apoptotic cells to limit inflammatory macrophage responses. J Mol Cell Biol. 2016 Oct 01; 8(5):426-438.
Mora J, Schlemmer A, Wittig I, Richter F, Putyrski M, Frank AC, Han Y, Jung M, Ernst A, Weigert A, Brüne B. PMID: 26892022.
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PubMed Mentions:
93 Fields:
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A Eukaryotic Sensor for Membrane Lipid Saturation. Mol Cell. 2016 07 07; 63(1):49-59.
Covino R, Ballweg S, Stordeur C, Michaelis JB, Puth K, Wernig F, Bahrami A, Ernst AM, Hummer G, Ernst R. PMID: 27320200.
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PubMed Mentions:
60 Fields:
Translation:
AnimalsCells
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Mitochondrial genomes are retained by selective constraints on protein targeting. Proc Natl Acad Sci U S A. 2015 Aug 18; 112(33):10154-61.
Björkholm P, Harish A, Hagström E, Ernst AM, Andersson SG. PMID: 26195779; PMCID: PMC4547212.
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PubMed Mentions:
47 Fields:
Translation:
HumansCells
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Inhibition of Ebola virus glycoprotein-mediated cytotoxicity by targeting its transmembrane domain and cholesterol. Nat Commun. 2015 Jul 09; 6:7688.
Hacke M, Björkholm P, Hellwig A, Himmels P, Ruiz de Almodóvar C, Brügger B, Wieland F, Ernst AM. PMID: 26158910.
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PubMed Mentions:
34 Fields:
Translation:
HumansAnimalsCells
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A structural portrait of the PDZ domain family. J Mol Biol. 2014 Oct 23; 426(21):3509-19.
Ernst A, Appleton BA, Ivarsson Y, Zhang Y, Gfeller D, Wiesmann C, Sidhu SS. PMID: 25158098.
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PubMed Mentions:
41 Fields:
Translation:
HumansCells