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Anand Sastry

Title(s)CMPTL AND DATA SCI RSCH SPEC 3, Bioengineering
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Restoration of fitness lost due to dysregulation of the pyruvate dehydrogenase complex is triggered by ribosomal binding site modifications. Cell Rep. 2021 Apr 06; 35(1):108961. Anand A, Olson CA, Sastry AV, Patel A, Szubin R, Yang L, Feist AM, Palsson BO. PMID: 33826886.
      View in: PubMed   Mentions:    Fields:    
    2. Independent component analysis recovers consistent regulatory signals from disparate datasets. PLoS Comput Biol. 2021 Feb 02; 17(2):e1008647. Sastry AV, Hu A, Heckmann D, Poudel S, Kavvas E, Palsson BO. PMID: 33529205.
      View in: PubMed   Mentions:    Fields:    
    3. iModulonDB: a knowledgebase of microbial transcriptional regulation derived from machine learning. Nucleic Acids Res. 2021 01 08; 49(D1):D112-D120. Rychel K, Decker K, Sastry AV, Phaneuf PV, Poudel S, Palsson BO. PMID: 33045728.
      View in: PubMed   Mentions: 2     Fields:    
    4. Machine learning uncovers independently regulated modules in the Bacillus subtilis transcriptome. Nat Commun. 2020 12 11; 11(1):6338. Rychel K, Sastry AV, Palsson BO. PMID: 33311500.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    5. Elucidation of Regulatory Modes for Five Two-Component Systems in Escherichia coli Reveals Novel Relationships. mSystems. 2020 Nov 10; 5(6). Choudhary KS, Kleinmanns JA, Decker K, Sastry AV, Gao Y, Szubin R, Seif Y, Palsson BO. PMID: 33172971.
      View in: PubMed   Mentions:
    6. The Bitome: digitized genomic features reveal fundamental genome organization. Nucleic Acids Res. 2020 10 09; 48(18):10157-10163. Lamoureux CR, Choudhary KS, King ZA, Sandberg TE, Gao Y, Sastry AV, Phaneuf PV, Choe D, Cho BK, Palsson BO. PMID: 32976587.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    7. Independent component analysis of E. coli's transcriptome reveals the cellular processes that respond to heterologous gene expression. Metab Eng. 2020 09; 61:360-368. Tan J, Sastry AV, Fremming KS, Bjørn SP, Hoffmeyer A, Seo S, Voldborg BG, Palsson BO. PMID: 32710928.
      View in: PubMed   Mentions:    Fields:    
    8. Revealing 29 sets of independently modulated genes in Staphylococcus aureus, their regulators, and role in key physiological response. Proc Natl Acad Sci U S A. 2020 07 21; 117(29):17228-17239. Poudel S, Tsunemoto H, Seif Y, Sastry AV, Szubin R, Xu S, Machado H, Olson CA, Anand A, Pogliano J, Nizet V, Palsson BO. PMID: 32616573.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    9. OxyR Is a Convergent Target for Mutations Acquired during Adaptation to Oxidative Stress-Prone Metabolic States. Mol Biol Evol. 2020 03 01; 37(3):660-667. Anand A, Chen K, Catoiu E, Sastry AV, Olson CA, Sandberg TE, Seif Y, Xu S, Szubin R, Yang L, Feist AM, Palsson BO. PMID: 31651953.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    10. The Escherichia coli transcriptome mostly consists of independently regulated modules. Nat Commun. 2019 12 04; 10(1):5536. Sastry AV, Gao Y, Szubin R, Hefner Y, Xu S, Kim D, Choudhary KS, Yang L, King ZA, Palsson BO. PMID: 31797920.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    11. Adaptive evolution reveals a tradeoff between growth rate and oxidative stress during naphthoquinone-based aerobic respiration. Proc Natl Acad Sci U S A. 2019 12 10; 116(50):25287-25292. Anand A, Chen K, Yang L, Sastry AV, Olson CA, Poudel S, Seif Y, Hefner Y, Phaneuf PV, Xu S, Szubin R, Feist AM, Palsson BO. PMID: 31767748.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    12. Adaptive laboratory evolution of Escherichia coli under acid stress. Microbiology (Reading). 2020 02; 166(2):141-148. Du B, Olson CA, Sastry AV, Fang X, Phaneuf PV, Chen K, Wu M, Szubin R, Xu S, Gao Y, Hefner Y, Feist AM, Palsson BO. PMID: 31625833.
      View in: PubMed   Mentions:
    13. Cellular responses to reactive oxygen species are predicted from molecular mechanisms. Proc Natl Acad Sci U S A. 2019 07 09; 116(28):14368-14373. Yang L, Mih N, Anand A, Park JH, Tan J, Yurkovich JT, Monk JM, Lloyd CJ, Sandberg TE, Seo SW, Kim D, Sastry AV, Phaneuf P, Gao Y, Broddrick JT, Chen K, Heckmann D, Szubin R, Hefner Y, Feist AM, Palsson BO. PMID: 31270234.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    14. BOFdat: Generating biomass objective functions for genome-scale metabolic models from experimental data. PLoS Comput Biol. 2019 04; 15(4):e1006971. Lachance JC, Lloyd CJ, Monk JM, Yang L, Sastry AV, Seif Y, Palsson BO, Rodrigue S, Feist AM, King ZA, Jacques PÉ. PMID: 31009451.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    15. The y-ome defines the 35% of Escherichia coli genes that lack experimental evidence of function. Nucleic Acids Res. 2019 03 18; 47(5):2446-2454. Ghatak S, King ZA, Sastry A, Palsson BO. PMID: 30698741.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    16. Pseudogene repair driven by selection pressure applied in experimental evolution. Nat Microbiol. 2019 03; 4(3):386-389. Anand A, Olson CA, Yang L, Sastry AV, Catoiu E, Choudhary KS, Phaneuf PV, Sandberg TE, Xu S, Hefner Y, Szubin R, Feist AM, Palsson BO. PMID: 30692668.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    17. Systematic discovery of uncharacterized transcription factors in Escherichia coli K-12 MG1655. Nucleic Acids Res. 2018 11 16; 46(20):10682-10696. Gao Y, Yurkovich JT, Seo SW, Kabimoldayev I, Dräger A, Chen K, Sastry AV, Fang X, Mih N, Yang L, Eichner J, Cho BK, Kim D, Palsson BO. PMID: 30137486.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    18. ssbio: a Python framework for structural systems biology. Bioinformatics. 2018 06 15; 34(12):2155-2157. Mih N, Brunk E, Chen K, Catoiu E, Sastry A, Kavvas E, Monk JM, Zhang Z, Palsson BO. PMID: 29444205.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    19. Escherichia coli B2 strains prevalent in inflammatory bowel disease patients have distinct metabolic capabilities that enable colonization of intestinal mucosa. BMC Syst Biol. 2018 06 11; 12(1):66. Fang X, Monk JM, Mih N, Du B, Sastry AV, Kavvas E, Seif Y, Smarr L, Palsson BO. PMID: 29890970.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    20. Recon3D enables a three-dimensional view of gene variation in human metabolism. Nat Biotechnol. 2018 03; 36(3):272-281. Brunk E, Sahoo S, Zielinski DC, Altunkaya A, Dräger A, Mih N, Gatto F, Nilsson A, Preciat Gonzalez GA, Aurich MK, Prlic A, Sastry A, Danielsdottir AD, Heinken A, Noronha A, Rose PW, Burley SK, Fleming RMT, Nielsen J, Thiele I, Palsson BO. PMID: 29457794.
      View in: PubMed   Mentions: 58     Fields:    Translation:Humans
    21. iML1515, a knowledgebase that computes Escherichia coli traits. Nat Biotechnol. 2017 10 11; 35(10):904-908. Monk JM, Lloyd CJ, Brunk E, Mih N, Sastry A, King Z, Takeuchi R, Nomura W, Zhang Z, Mori H, Feist AM, Palsson BO. PMID: 29020004.
      View in: PubMed   Mentions: 55     Fields:    Translation:Cells
    22. Global transcriptional regulatory network for Escherichia coli robustly connects gene expression to transcription factor activities. Proc Natl Acad Sci U S A. 2017 09 19; 114(38):10286-10291. Fang X, Sastry A, Mih N, Kim D, Tan J, Yurkovich JT, Lloyd CJ, Gao Y, Yang L, Palsson BO. PMID: 28874552.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    23. Machine learning in computational biology to accelerate high-throughput protein expression. Bioinformatics. 2017 Aug 15; 33(16):2487-2495. Sastry A, Monk J, Tegel H, Uhlen M, Palsson BO, Rockberg J, Brunk E. PMID: 28398465.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    24. Multi-omic data integration enables discovery of hidden biological regularities. Nat Commun. 2016 10 26; 7:13091. Ebrahim A, Brunk E, Tan J, O'Brien EJ, Kim D, Szubin R, Lerman JA, Lechner A, Sastry A, Bordbar A, Feist AM, Palsson BO. PMID: 27782110.
      View in: PubMed   Mentions: 31     Fields:    Translation:Cells
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