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COR758, a negative allosteric modulator of GABAB receptors. Neuropharmacology. 2021 05 15; 189:108537.
Porcu A, Mostallino R, Serra V, Melis M, Sogos V, Beggiato S, Ferraro L, Manetti F, Gianibbi B, Bettler B, Corelli F, Mugnaini C, Castelli MP. PMID: 33798546.
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Bioactive Triterpenes of Protium heptaphyllum Gum Resin Extract Display Cholesterol-Lowering Potential. Int J Mol Sci. 2021 Mar 06; 22(5).
Mannino G, Iovino P, Lauria A, Genova T, Asteggiano A, Notarbartolo M, Porcu A, Serio G, Chinigò G, Occhipinti A, Capuzzo A, Medana C, Munaron L, Gentile C. PMID: 33800828.
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2 Fields:
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HumansCells
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Chemical Profile and Biological Activity of Cherimoya (Annona cherimola Mill.) and Atemoya (Annona atemoya) Leaves. Molecules. 2020 Jun 04; 25(11).
Mannino G, Gentile C, Porcu A, Agliassa C, Caradonna F, Bertea CM. PMID: 32512771.
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HumansAnimalsCells
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Vulnerability to helpless behavior is regulated by the circadian clock component CRYPTOCHROME in the mouse nucleus accumbens. Proc Natl Acad Sci U S A. 2020 06 16; 117(24):13771-13782.
Porcu A, Vaughan M, Nilsson A, Arimoto N, Lamia K, Welsh DK. PMID: 32487727.
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2 Fields:
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HumansAnimalsCells
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Pharmacological Manipulation of the Circadian Clock: A Possible Approach to the Management of Bipolar Disorder. CNS Drugs. 2019 10; 33(10):981-999.
Porcu A, Gonzalez R, McCarthy MJ. PMID: 31625128.
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1 Fields:
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HumansAnimalsCells
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Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR. Cell. 2018 06 28; 174(1):72-87.e32.
Walton ZE, Patel CH, Brooks RC, Yu Y, Ibrahim-Hashim A, Riddle M, Porcu A, Jiang T, Ecker BL, Tameire F, Koumenis C, Weeraratna AT, Welsh DK, Gillies R, Alwine JC, Zhang L, Powell JD, Dang CV. PMID: 29861175.
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56 Fields:
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AnimalsCells
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Rimonabant, a potent CB1 cannabinoid receptor antagonist, is a Gai/o protein inhibitor. Neuropharmacology. 2018 05 01; 133:107-120.
Porcu A, Melis M, Turecek R, Ullrich C, Mocci I, Bettler B, Gessa GL, Castelli MP. PMID: 29407764.
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3 Fields:
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HumansAnimalsCells
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Photoperiod-Induced Neuroplasticity in the Circadian System. Neural Plast. 2018; 2018:5147585.
Porcu A, Riddle M, Dulcis D, Welsh DK. PMID: 29681926.
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4 Fields:
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HumansAnimals
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In vitro and in vivo pharmacological characterization of SSD114, a novel GABAB positive allosteric modulator. Eur J Pharmacol. 2016 Nov 15; 791:115-123.
Porcu A, Lobina C, Giunta D, Solinas M, Mugnaini C, Castelli MP. PMID: 27578262.
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1 Fields:
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AnimalsCells
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Gas chromatography-mass spectrometry metabolomics of goat milk with different polymorphism at the aS1-casein genotype locus. J Dairy Sci. 2016 Aug; 99(8):6046-6051.
Caboni P, Murgia A, Porcu A, Demuru M, Pulina G, Nudda A. PMID: 27289154.
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3 Fields:
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Animals
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Native CB1 receptor affinity, intrinsic activity and accumbens shell dopamine stimulant properties of third generation SPICE/K2 cannabinoids: BB-22, 5F-PB-22, 5F-AKB-48 and STS-135. Neuropharmacology. 2016 06; 105:630-638.
De Luca MA, Castelli MP, Loi B, Porcu A, Martorelli M, Miliano C, Kellett K, Davidson C, Stair JL, Schifano F, Di Chiara G. PMID: 26686391.
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24 Fields:
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AnimalsCells
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Synthesis and pharmacological characterization of 2-(acylamino)thiophene derivatives as metabolically stable, orally effective, positive allosteric modulators of the GABAB receptor. J Med Chem. 2013 May 09; 56(9):3620-35.
Mugnaini C, Pedani V, Casu A, Lobina C, Casti A, Maccioni P, Porcu A, Giunta D, Lamponi S, Solinas M, Dragoni S, Valoti M, Colombo G, Castelli MP, Gessa GL, Corelli F. PMID: 23544432.
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8 Fields:
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AnimalsCells