Aleksandra Babicheva

Title(s)Assistant Project Scientist, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Biography 
    Collapse Education and Training
    Astrakhan State Technical University, RussiaBS2006Biology
    Astrakhan State University, RussiaMS2009Human physiology
    Astrakhan State University, RussiaPhD2010Human physiology
    Collapse Awards and Honors
    Arizona Physiological Society2016The Best Postdoctoral Poster Award
    American Thoracic Society2017The Abstract Scholarship
    American Physiological Society2018Caroline tum Suden/Frances Hellebrandt Professional Opportunity Award

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Pathogenic role of miR-29b in pulmonary hypertension
    American Heart Association 20POST35210959Jan 1, 2020 - Dec 31, 2021
    Role: PI

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. TRPC6, a Therapeutic Target for Pulmonary Hypertension. Am J Physiol Lung Cell Mol Physiol. 2021 Oct 27. Jain PP, Lai N, Xiong M, Chen J, Babicheva A, Zhao T, Parmisano S, Zhao M, Paquin C, Matti M, Powers R, Balistrieri A, Kim NH, Valdez-Jasso D, Thistlethwaite PA, Shyy JY, Wang J, Garcia JGN, Makino A, Yuan JX. PMID: 34704831.
      View in: PubMed   Mentions:
    2. Endothelial Upregulation of Mechanosensitive Channel Piezo1 in Pulmonary Hypertension. Am J Physiol Cell Physiol. 2021 Oct 20. Wang Z, Chen J, Babicheva A, Jain PP, Rodriguez M, Ayon RJ, Ravellette KS, Wu L, Balistrieri F, Tang H, Wu X, Zhao T, Black SM, Desai AA, Garcia JGN, Sun X, Shyy JY, Valdez-Jasso D, Thistlethwaite PA, Makino A, Wang J, Yuan JX. PMID: 34669509.
      View in: PubMed   Mentions:    Fields:    
    3. Mouse model of experimental pulmonary hypertension: Lung angiogram and right heart catheterization. Pulm Circ. 2021 Oct-Dec; 11(4):20458940211041512. Xiong M, Jain PP, Chen J, Babicheva A, Zhao T, Alotaibi M, Kim NH, Lai N, Izadi A, Rodriguez M, Li J, Balistrieri A, Balistrieri F, Parmisano S, Sun X, Voldez-Jasso D, Shyy JY, Thistlethwaite PA, Wang J, Makino A, Yuan JX. PMID: 34531976; PMCID: PMC8438952.
      View in: PubMed   Mentions:
    4. Upregulation of Calcium Homeostasis Modulators in Contractile-To-Proliferative Phenotypical Transition of Pulmonary Arterial Smooth Muscle Cells. Front Physiol. 2021; 12:714785. Rodriguez M, Chen J, Jain PP, Babicheva A, Xiong M, Li J, Lai N, Zhao T, Hernandez M, Balistrieri A, Parmisano S, Simonson T, Breen E, Valdez-Jasso D, Thistlethwaite PA, Shyy JY, Wang J, Garcia JGN, Makino A, Yuan JX. PMID: 34408668; PMCID: PMC8364962.
      View in: PubMed   Mentions:
    5. Halofuginone, a promising drug for treatment of pulmonary hypertension. Br J Pharmacol. 2021 09; 178(17):3373-3394. Jain PP, Zhao T, Xiong M, Song S, Lai N, Zheng Q, Chen J, Carr SG, Babicheva A, Izadi A, Rodriguez M, Rahimi S, Balistrieri F, Rahimi S, Simonson T, Valdez-Jasso D, Thistlethwaite PA, Shyy JY, Wang J, Makino A, Yuan JX. PMID: 33694155.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    6. mTOR Signaling in Pulmonary Vascular Disease: Pathogenic Role and Therapeutic Target. Int J Mol Sci. 2021 Feb 21; 22(4). Babicheva A, Makino A, Yuan JX. PMID: 33670032; PMCID: PMC7926633.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    7. Transcriptomic profiles in pulmonary arterial hypertension associate with disease severity and identify novel candidate genes. Pulm Circ. 2020 Oct-Dec; 10(4):2045894020968531. Romanoski CE, Qi X, Sangam S, Vanderpool RR, Stearman RS, Conklin A, Gonzalez-Garay M, Rischard F, Ayon RJ, Wang J, Simonson T, Babicheva A, Shi Y, Tang H, Makino A, Kanthi Y, Geraci MW, Garcia JGN, Yuan JX, Desai AA. PMID: 33343881; PMCID: PMC7727059.
      View in: PubMed   Mentions:
    8. Revisiting the mechanism of hypoxic pulmonary vasoconstriction using isolated perfused/ventilated mouse lung. Pulm Circ. 2020 Oct-Dec; 10(4):2045894020956592. Jain PP, Hosokawa S, Xiong M, Babicheva A, Zhao T, Rodriguez M, Rahimi S, Pourhashemi K, Balistrieri F, Lai N, Malhotra A, Shyy JY, Valdez-Jasso D, Thistlethwaite PA, Makino A, Yuan JX. PMID: 33282184; PMCID: PMC7691930.
      View in: PubMed   Mentions: 2  
    9. Endothelial platelet-derived growth factor-mediated activation of smooth muscle platelet-derived growth factor receptors in pulmonary arterial hypertension. Pulm Circ. 2020 Jul-Sep; 10(3):2045894020948470. Wu K, Tang H, Lin R, Carr SG, Wang Z, Babicheva A, Ayon RJ, Jain PP, Xiong M, Rodriguez M, Rahimi S, Balistrieri F, Rahimi S, Valdez-Jasso D, Simonson TS, Desai AA, Garcia JGN, Shyy JY, Thistlethwaite PA, Wang J, Makino A, Yuan JX. PMID: 33294172; PMCID: PMC7707860.
      View in: PubMed   Mentions: 2  
    10. Hypoxia-induced pulmonary hypertension-Utilizing experiments of nature. Br J Pharmacol. 2021 01; 178(1):121-131. Gassmann M, Cowburn A, Gu H, Li J, Rodriguez M, Babicheva A, Jain PP, Xiong M, Gassmann NN, Yuan JX, Wilkins MR, Zhao L. PMID: 32464698.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    11. Direct Extracellular NAMPT Involvement in Pulmonary Hypertension and Vascular Remodeling. Transcriptional Regulation by SOX and HIF-2α. Am J Respir Cell Mol Biol. 2020 07; 63(1):92-103. Sun X, Sun BL, Babicheva A, Vanderpool R, Oita RC, Casanova N, Tang H, Gupta A, Lynn H, Gupta G, Rischard F, Sammani S, Kempf CL, Moreno-Vinasco L, Ahmed M, Camp SM, Wang J, Desai AA, Yuan JX, Garcia JGN. PMID: 32142369; PMCID: PMC7328254.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    12. Notch enhances Ca2+ entry by activating calcium-sensing receptors and inhibiting voltage-gated K+ channels. Am J Physiol Cell Physiol. 2020 05 01; 318(5):C954-C968. Song S, Babicheva A, Zhao T, Ayon RJ, Rodriguez M, Rahimi S, Balistrieri F, Harrington A, Shyy JY, Thistlethwaite PA, Makino A, Yuan JX. PMID: 32186932; PMCID: PMC7294324.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    13. MicroRNA-mediated downregulation of K+ channels in pulmonary arterial hypertension. Am J Physiol Lung Cell Mol Physiol. 2020 01 01; 318(1):L10-L26. Babicheva A, Ayon RJ, Zhao T, Ek Vitorin JF, Pohl NM, Yamamura A, Yamamura H, Quinton BA, Ba M, Wu L, Ravellette KS, Rahimi S, Balistrieri F, Harrington A, Vanderpool RR, Thistlethwaite PA, Makino A, Yuan JX. PMID: 31553627; PMCID: PMC6985878.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    14. KCNK3 Channel: A New Player in the Field of Pulmonary Vascular Disease. Circ Res. 2019 09 13; 125(7):696-698. Babicheva A, Zhao T, Yuan JX. PMID: 31513487.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    15. Endothelial Notch1 in Pulmonary Hypertension. Circ Res. 2019 01 18; 124(2):176-179. Babicheva A, Yuan JX. PMID: 30653427; PMCID: PMC6368966.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    16. Divergent changes of p53 in pulmonary arterial endothelial and smooth muscle cells involved in the development of pulmonary hypertension. . 2019 01 01; 316(1):L216-L228. Wang Z, Yang K, Zheng Q, Zhang C, Tang H, Babicheva A, Jiang Q, Li M, Chen Y, Carr SG, Wu K, Zhang Q, Balistrieri A, Wang C, Song S, Ayon RJ, Desai AA, Black SM, Garcia JGN, Makino A, Yuan JX, Lu W, Wang J. PMID: 30358436; PMCID: PMC6383500.
      View in: PubMed   Mentions: 8  Translation:AnimalsCells
    17. STIM2 (Stromal Interaction Molecule 2)-Mediated Increase in Resting Cytosolic Free Ca2+ Concentration Stimulates PASMC Proliferation in Pulmonary Arterial Hypertension. Hypertension. 2018 03; 71(3):518-529. Song S, Carr SG, McDermott KM, Rodriguez M, Babicheva A, Balistrieri A, Ayon RJ, Wang J, Makino A, Yuan JX. PMID: 29358461; PMCID: PMC5955710.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    18. Endothelial dysfunction in pulmonary arterial hypertension: an evolving landscape (2017 Grover Conference Series). Pulm Circ. 2018 Jan-Mar; 8(1):2045893217752912. Ranchoux B, Harvey LD, Ayon RJ, Babicheva A, Bonnet S, Chan SY, Yuan JX, Perez VJ. PMID: 29283043; PMCID: PMC5798691.
      View in: PubMed   Mentions: 40  
    19. Endothelial HIF-2α contributes to severe pulmonary hypertension due to endothelial-to-mesenchymal transition. Am J Physiol Lung Cell Mol Physiol. 2018 02 01; 314(2):L256-L275. Tang H, Babicheva A, McDermott KM, Gu Y, Ayon RJ, Song S, Wang Z, Gupta A, Zhou T, Sun X, Dash S, Wang Z, Balistrieri A, Zheng Q, Cordery AG, Desai AA, Rischard F, Khalpey Z, Wang J, Black SM, Garcia JGN, Makino A, Yuan JX. PMID: 29074488; PMCID: PMC5866501.
      View in: PubMed   Mentions: 61  Translation:AnimalsCells
    20. Capsaicin-induced Ca2+ signaling is enhanced via upregulated TRPV1 channels in pulmonary artery smooth muscle cells from patients with idiopathic PAH. . 2017 03 01; 312(3):L309-L325. Song S, Ayon RJ, Yamamura A, Yamamura H, Dash S, Babicheva A, Tang H, Sun X, Cordery AG, Khalpey Z, Black SM, Desai AA, Rischard F, McDermott KM, Garcia JG, Makino A, Yuan JX. PMID: 27979859; PMCID: PMC5374303.
      View in: PubMed   Mentions: 20  Translation:HumansCells
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