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Walter Kaye

Title(s)Professor, Psychiatry
SchoolHealth Sciences
Phone858-534-3951
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    Biography

    Dr. Kaye attended Ohio State Medical School, trained in neurology at the University of Southern California, trained in psychiatry at the University of California, Los Angeles, did research for 7 years on eating disorders at the National Institute of Mental Health, and was on the faculty of the University of Pittsburgh for 20 years until joining UCSD. His current research is focused on exploring the relationship between brain and behavior using brain imaging and genetics to understand the cause of altered appetite, anxiety, reward, and other symptoms. At UCSD, Dr. Kaye has founded a treatment program for eating disorders that is using new insights into temperament and neurobiology to develop more effective treatments. Dr. Kaye has an international reputation in the field of eating disorders and is the author of more than 300 publications.

    Research Interests

    Eating Disorders Research

    Clinical Information

    Dr. Kaye's clinical information

    Collapse Research 
    Collapse Research Activities and Funding
    Monoamine Contributions to Neurocircuitry in Eating Disorders
    NIH/NIMH R01MH092793Dec 1, 2010 - Feb 29, 2016
    Role: Principal Investigator
    Family Therapy in the Treatment of Adolescent Anorexia Nervosa
    NIH/NIMH U01MH076286Sep 19, 2006 - Apr 30, 2012
    Role: Principal Investigator
    Genetics of Anorexia Nervosa
    NIH/NIMH R01MH066122Sep 13, 2002 - Jul 31, 2008
    Role: Principal Investigator
    PET IMAGING AND SEROTONIN LIGANDS IN EATING DISORDERS
    NIH/NIMH K05MH001894Feb 15, 2001 - Jan 31, 2006
    Role: Principal Investigator
    VULNERABILITY TO SUBSTANCE ABUSE IN HUMANS
    NIH/NIDA R21DA009369Jul 1, 1995 - Jun 30, 1998
    Role: Principal Investigator
    GENETIC EPIDEMIOLOGY--ALCOHOL ABUSE IN EATING DISORDERS
    NIH/NIAAA R01AA008983Aug 1, 1991 - Jul 31, 1995
    Role: Principal Investigator
    Serotonin - A Trait Disturbance in Anorexia Nervosa?
    NIH/NIMH R01MH046001Aug 1, 1990 - Feb 28, 2010
    Role: Principal Investigator
    Neurobiology of Anorexia and Bulimia Nervosa
    NIH/NIMH R01MH042984Sep 30, 1988 - Mar 31, 2014
    Role: Principal Investigator
    General Clinical Research Center
    NIH M01RR000056Dec 1, 1978 - Mar 31, 2009
    Role: Co-Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Berner LA, Romero EM, Reilly EE, Lavender JM, Kaye WH, Wierenga CE. Task-switching inefficiencies in currently ill, but not remitted anorexia nervosa. Int J Eat Disord. 2019 Oct 04. PMID: 31584714.
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    2. Marzola E, Fassino S, Migliaretti G, Abbate-Daga G, Kaye WH. Development and validation of the Premorbid Childhood Traits Questionnaire (PCT-Q) in eating disorders. Eat Weight Disord. 2019 Jul 16. PMID: 31313252.
      View in: PubMed
    3. Watson HJ, Yilmaz Z, Thornton LM, Hübel C, Coleman JRI, Gaspar HA, Bryois J, Hinney A, Leppä VM, Mattheisen M, Medland SE, Ripke S, Yao S, Giusti-Rodríguez P, Hanscombe KB, Purves KL, Adan RAH, Alfredsson L, Ando T, Andreassen OA, Baker JH, Berrettini WH, Boehm I, Boni C, Perica VB, Buehren K, Burghardt R, Cassina M, Cichon S, Clementi M, Cone RD, Courtet P, Crow S, Crowley JJ, Danner UN, Davis OSP, de Zwaan M, Dedoussis G, Degortes D, DeSocio JE, Dick DM, Dikeos D, Dina C, Dmitrzak-Weglarz M, Docampo E, Duncan LE, Egberts K, Ehrlich S, Escaramís G, Esko T, Estivill X, Farmer A, Favaro A, Fernández-Aranda F, Fichter MM, Fischer K, Föcker M, Foretova L, Forstner AJ, Forzan M, Franklin CS, Gallinger S, Giegling I, Giuranna J, Gonidakis F, Gorwood P, Mayora MG, Guillaume S, Guo Y, Hakonarson H, Hatzikotoulas K, Hauser J, Hebebrand J, Helder SG, Herms S, Herpertz-Dahlmann B, Herzog W, Huckins LM, Hudson JI, Imgart H, Inoko H, Janout V, Jiménez-Murcia S, Julià A, Kalsi G, Kaminská D, Kaprio J, Karhunen L, Karwautz A, Kas MJH, Kennedy JL, Keski-Rahkonen A, Kiezebrink K, Kim YR, Klareskog L, Klump KL, Knudsen GPS, La Via MC, Le Hellard S, Levitan RD, Li D, Lilenfeld L, Lin BD, Lissowska J, Luykx J, Magistretti PJ, Maj M, Mannik K, Marsal S, Marshall CR, Mattingsdal M, McDevitt S, McGuffin P, Metspalu A, Meulenbelt I, Micali N, Mitchell K, Monteleone AM, Monteleone P, Munn-Chernoff MA, Nacmias B, Navratilova M, Ntalla I, O'Toole JK, Ophoff RA, Padyukov L, Palotie A, Pantel J, Papezova H, Pinto D, Rabionet R, Raevuori A, Ramoz N, Reichborn-Kjennerud T, Ricca V, Ripatti S, Ritschel F, Roberts M, Rotondo A, Rujescu D, Rybakowski F, Santonastaso P, Scherag A, Scherer SW, Schmidt U, Schork NJ, Schosser A, Seitz J, Slachtova L, Slagboom PE, Slof-Op 't Landt MCT, Slopien A, Sorbi S, Swiatkowska B, Szatkiewicz JP, Tachmazidou I, Tenconi E, Tortorella A, Tozzi F, Treasure J, Tsitsika A, Tyszkiewicz-Nwafor M, Tziouvas K, van Elburg AA, van Furth EF, Wagner G, Walton E, Widen E, Zeggini E, Zerwas S, Zipfel S, Bergen AW, Boden JM, Brandt H, Crawford S, Halmi KA, Horwood LJ, Johnson C, Kaplan AS, Kaye WH, Mitchell JE, Olsen CM, Pearson JF, Pedersen NL, Strober M, Werge T, Whiteman DC, Woodside DB, Stuber GD, Gordon S, Grove J, Henders AK, Juréus A, Kirk KM, Larsen JT, Parker R, Petersen L, Jordan J, Kennedy M, Montgomery GW, Wade TD, Birgegård A, Lichtenstein P, Norring C, Landén M, Martin NG, Mortensen PB, Sullivan PF, Breen G, Bulik CM. Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa. Nat Genet. 2019 Jul 15. PMID: 31308545.
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    4. Dimitropoulos G, Lock JD, Agras WS, Brandt H, Halmi KA, Jo B, Kaye WH, Pinhas L, Wilfley DE, Woodside DB. Therapist adherence to family-based treatment for adolescents with anorexia nervosa: A multi-site exploratory study. Eur Eat Disord Rev. 2019 Jul 11. PMID: 31297906.
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    5. Stedal K, Ely AV, Kurniadi N, Lopez E, Kaye WH, Wierenga CE. A process approach to verbal memory assessment: Exploratory evidence of inefficient learning in women remitted from anorexia nervosa. J Clin Exp Neuropsychol. 2019 Aug; 41(6):653-663. PMID: 31060425.
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    6. Reilly EE, Brown TA, Gray EK, Kaye WH, Menzel JE. Exploring the cooccurrence of behavioural phenotypes for avoidant/restrictive food intake disorder in a partial hospitalization sample. Eur Eat Disord Rev. 2019 Mar 13. PMID: 30868707.
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    7. Berner LA, Simmons AN, Wierenga CE, Bischoff-Grethe A, Paulus MP, Bailer UF, Kaye WH. Altered anticipation and processing of aversive interoceptive experience among women remitted from bulimia nervosa. Neuropsychopharmacology. 2019 06; 44(7):1265-1273. PMID: 30840983.
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    8. Duffy ME, Rogers ML, Joiner TE, Bergen AW, Berrettini W, Bulik CM, Brandt H, Crawford S, Crow S, Fichter M, Halmi K, Kaplan AS, Klump KL, Lilenfeld L, Magistretti PJ, Mitchell J, Schork NJ, Strober M, Thornton LM, Treasure J, Woodside B, Kaye WH, Keel PK. An investigation of indirect effects of personality features on anorexia nervosa severity through interoceptive dysfunction in individuals with lifetime anorexia nervosa diagnoses. Int J Eat Disord. 2019 Feb; 52(2):200-205. PMID: 30636025.
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    9. Menzel JE, Reilly EE, Luo TJ, Kaye WH. Conceptualizing the role of disgust in avoidant/restrictive food intake disorder: Implications for the etiology and treatment of selective eating. Int J Eat Disord. 2019 Jan 09. PMID: 30628116.
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    10. Reilly EE, Lavender JM, Berner LA, Brown TA, Wierenga CE, Kaye WH. Could repetitive negative thinking interfere with corrective learning? The example of anorexia nervosa. Int J Eat Disord. 2018 Dec 31. PMID: 30597593.
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    11. Berner LA, Brown TA, Lavender JM, Lopez E, Wierenga CE, Kaye WH. Neuroendocrinology of reward in anorexia nervosa and bulimia nervosa: Beyond leptin and ghrelin. Mol Cell Endocrinol. 2018 Nov 02. PMID: 30395874.
      View in: PubMed
    12. Thornton LM, Munn-Chernoff MA, Baker JH, Juréus A, Parker R, Henders AK, Larsen JT, Petersen L, Watson HJ, Yilmaz Z, Kirk KM, Gordon S, Leppä VM, Martin FC, Whiteman DC, Olsen CM, Werge TM, Pedersen NL, Kaye W, Bergen AW, Halmi KA, Strober M, Kaplan AS, Woodside DB, Mitchell J, Johnson CL, Brandt H, Crawford S, Horwood LJ, Boden JM, Pearson JF, Duncan LE, Grove J, Mattheisen M, Jordan J, Kennedy MA, Birgegård A, Lichtenstein P, Norring C, Wade TD, Montgomery GW, Martin NG, Landén M, Mortensen PB, Sullivan PF, Bulik CM. The Anorexia Nervosa Genetics Initiative (ANGI): Overview and methods. Contemp Clin Trials. 2018 Nov; 74:61-69. PMID: 30287268.
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    13. Guarda AS, Wonderlich S, Kaye W, Attia E. A path to defining excellence in intensive treatment for eating disorders. Int J Eat Disord. 2018 09; 51(9):1051-1055. PMID: 30189103.
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    14. Levinson CA, Zerwas SC, Brosof LC, Thornton LM, Strober M, Pivarunas B, Crowley JJ, Yilmaz Z, Berrettini WH, Brandt H, Crawford S, Fichter MM, Halmi KA, Johnson C, Kaplan AS, La Via M, Mitchell J, Rotondo A, Woodside DB, Kaye WH, Bulik CM. Associations between dimensions of anorexia nervosa and obsessive-compulsive disorder: An examination of personality and psychological factors in patients with anorexia nervosa. Eur Eat Disord Rev. 2019 03; 27(2):161-172. PMID: 30136346.
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    15. Yue L, Wang Y, Kaye WH, Kang Q, Huang JB, Cheung EFC, Xiao SF, Wang Z, Chen J, Chan RCK. Structural alterations in the caudate nucleus and precuneus in un-medicated anorexia nervosa patients. Psychiatry Res Neuroimaging. 2018 Nov 30; 281:12-18. PMID: 30212787.
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    16. Bischoff-Grethe A, Wierenga CE, Berner LA, Simmons AN, Bailer U, Paulus MP, Kaye WH. Neural hypersensitivity to pleasant touch in women remitted from anorexia nervosa. Transl Psychiatry. 2018 08 16; 8(1):161. PMID: 30115929.
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    17. Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu D, Lee PH, Turley P, Grenier-Boley B, Chouraki V, Kamatani Y, Berr C, Letenneur L, Hannequin D, Amouyel P, Boland A, Deleuze JF, Duron E, Vardarajan BN, Reitz C, Goate AM, Huentelman MJ, Kamboh MI, Larson EB, Rogaeva E, St George-Hyslop P, Hakonarson H, Kukull WA, Farrer LA, Barnes LL, Beach TG, Demirci FY, Head E, Hulette CM, Jicha GA, Kauwe JSK, Kaye JA, Leverenz JB, Levey AI, Lieberman AP, Pankratz VS, Poon WW, Quinn JF, Saykin AJ, Schneider LS, Smith AG, Sonnen JA, Stern RA, Van Deerlin VM, Van Eldik LJ, Harold D, Russo G, Rubinsztein DC, Bayer A, Tsolaki M, Proitsi P, Fox NC, Hampel H, Owen MJ, Mead S, Passmore P, Morgan K, Nöthen MM, Rossor M, Lupton MK, Hoffmann P, Kornhuber J, Lawlor B, McQuillin A, Al-Chalabi A, Bis JC, Ruiz A, Boada M, Seshadri S, Beiser A, Rice K, van der Lee SJ, De Jager PL, Geschwind DH, Riemenschneider M, Riedel-Heller S, Rotter JI, Ransmayr G, Hyman BT, Cruchaga C, Alegret M, Winsvold B, Palta P, Farh KH, Cuenca-Leon E, Furlotte N, Kurth T, Ligthart L, Terwindt GM, Freilinger T, Ran C, Gordon SD, Borck G, Adams HHH, Lehtimäki T, Wedenoja J, Buring JE, Schürks M, Hrafnsdottir M, Hottenga JJ, Penninx B, Artto V, Kaunisto M, Vepsäläinen S, Martin NG, Montgomery GW, Kurki MI, Hämäläinen E, Huang H, Huang J, Sandor C, Webber C, Muller-Myhsok B, Schreiber S, Salomaa V, Loehrer E, Göbel H, Macaya A, Pozo-Rosich P, Hansen T, Werge T, Kaprio J, Metspalu A, Kubisch C, Ferrari MD, Belin AC, van den Maagdenberg AMJM, Zwart JA, Boomsma D, Eriksson N, Olesen J, Chasman DI, Nyholt DR, Avbersek A, Baum L, Berkovic S, Bradfield J, Buono R, Catarino CB, Cossette P, De Jonghe P, Depondt C, Dlugos D, Ferraro TN, French J, Hjalgrim H, Jamnadas-Khoda J, Kälviäinen R, Kunz WS, Lerche H, Leu C, Lindhout D, Lo W, Lowenstein D, McCormack M, Møller RS, Molloy A, Ng PW, Oliver K, Privitera M, Radtke R, Ruppert AK, Sander T, Schachter S, Schankin C, Scheffer I, Schoch S, Sisodiya SM, Smith P, Sperling M, Striano P, Surges R, Thomas GN, Visscher F, Whelan CD, Zara F, Heinzen EL, Marson A, Becker F, Stroink H, Zimprich F, Gasser T, Gibbs R, Heutink P, Martinez M, Morris HR, Sharma M, Ryten M, Mok KY, Pulit S, Bevan S, Holliday E, Attia J, Battey T, Boncoraglio G, Thijs V, Chen WM, Mitchell B, Rothwell P, Sharma P, Sudlow C, Vicente A, Markus H, Kourkoulis C, Pera J, Raffeld M, Silliman S, Boraska Perica V, Thornton LM, Huckins LM, William Rayner N, Lewis CM, Gratacos M, Rybakowski F, Keski-Rahkonen A, Raevuori A, Hudson JI, Reichborn-Kjennerud T, Monteleone P, Karwautz A, Mannik K, Baker JH, O'Toole JK, Trace SE, Davis OSP, Helder SG, Ehrlich S, Herpertz-Dahlmann B, Danner UN, van Elburg AA, Clementi M, Forzan M, Docampo E, Lissowska J, Hauser J, Tortorella A, Maj M, Gonidakis F, Tziouvas K, Papezova H, Yilmaz Z, Wagner G, Cohen-Woods S, Herms S, Julià A, Rabionet R, Dick DM, Ripatti S, Andreassen OA, Espeseth T, Lundervold AJ, Steen VM, Pinto D, Scherer SW, Aschauer H, Schosser A, Alfredsson L, Padyukov L, Halmi KA, Mitchell J, Strober M, Bergen AW, Kaye W, Szatkiewicz JP, Cormand B, Ramos-Quiroga JA, Sánchez-Mora C, Ribasés M, Casas M, Hervas A, Arranz MJ, Haavik J, Zayats T, Johansson S, Williams N, Dempfle A, Rothenberger A, Kuntsi J, Oades RD, Banaschewski T, Franke B, Buitelaar JK, Arias Vasquez A, Doyle AE, Reif A, Lesch KP, Freitag C, Rivero O, Palmason H, Romanos M, Langley K, Rietschel M, Witt SH, Dalsgaard S, Børglum AD, Waldman I, Wilmot B, Molly N, Bau CHD, Crosbie J, Schachar R, Loo SK, McGough JJ, Grevet EH, Medland SE, Robinson E, Weiss LA, Bacchelli E, Bailey A, Bal V, Battaglia A, Betancur C, Bolton P, Cantor R, Celestino-Soper P, Dawson G, De Rubeis S, Duque F, Green A, Klauck SM, Leboyer M, Levitt P, Maestrini E, Mane S, De-Luca DM, Parr J, Regan R, Reichenberg A, Sandin S, Vorstman J, Wassink T, Wijsman E, Cook E, Santangelo S, Delorme R, et al. Analysis of shared heritability in common disorders of the brain. Science. 2018 06 22; 360(6395). PMID: 29930110.
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    18. Anderson LK, Claudat K, Cusack A, Brown TA, Trim J, Rockwell R, Nakamura T, Gomez L, Kaye WH. Differences in emotion regulation difficulties among adults and adolescents across eating disorder diagnoses. J Clin Psychol. 2018 10; 74(10):1867-1873. PMID: 29756232.
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    19. Wierenga CE, Hill L, Knatz Peck S, McCray J, Greathouse L, Peterson D, Scott A, Eisler I, Kaye WH. The acceptability, feasibility, and possible benefits of a neurobiologically-informed 5-day multifamily treatment for adults with anorexia nervosa. Int J Eat Disord. 2018 08; 51(8):863-869. PMID: 29722047.
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    20. Gray E, Chen T, Menzel J, Schwartz T, Kaye WH. Mirtazapine and Weight Gain in Avoidant and Restrictive Food Intake Disorder. J Am Acad Child Adolesc Psychiatry. 2018 04; 57(4):288-289. PMID: 29588055.
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    21. Brown TA, Cusack A, Anderson LK, Trim J, Nakamura T, Trunko ME, Kaye WH. Efficacy of a partial hospital programme for adults with eating disorders. Eur Eat Disord Rev. 2018 05; 26(3):241-252. PMID: 29542211.
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    22. Chen EY, Kaye WH. We Are Only at the Tip of the Iceberg: A Commentary on Higher Levels of Care for Anorexia Nervosa. Clin Psychol (New York). 2018 Mar; 25(1). PMID: 30344376.
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    23. Sadeh-Sharvit S, Arnow KD, Osipov L, Lock JD, Jo B, Pajarito S, Brandt H, Dodge E, Halmi KA, Johnson C, Kaye W, Wilfley D, Agras WS. Are parental self-efficacy and family flexibility mediators of treatment for anorexia nervosa? Int J Eat Disord. 2018 03; 51(3):275-280. PMID: 29314160.
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    24. Brown TA, Avery JC, Jones MD, Anderson LK, Wierenga CE, Kaye WH. The Impact of Alexithymia on Emotion Dysregulation in Anorexia Nervosa and Bulimia Nervosa over Time. Eur Eat Disord Rev. 2018 Mar; 26(2):150-155. PMID: 29266572.
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    25. Trunko ME, Schwartz TA, Berner LA, Cusack A, Nakamura T, Bailer UF, Chen JY, Kaye WH. A pilot open series of lamotrigine in DBT-treated eating disorders characterized by significant affective dysregulation and poor impulse control. Borderline Personal Disord Emot Dysregul. 2017; 4:21. PMID: 29043085.
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    26. Strigo IA, Murray SB, Simmons AN, Bernard RS, Huang JS, Kaye WH. The clinical application of fMRI data in a single-patient diagnostic conundrum: Classifying brain response to experimental pain to distinguish between gastrointestinal, depressive and eating disorder symptoms. J Clin Neurosci. 2017 Nov; 45:149-153. PMID: 28823587.
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    27. Anderson LK, Reilly EE, Berner L, Wierenga CE, Jones MD, Brown TA, Kaye WH, Cusack A. Treating Eating Disorders at Higher Levels of Care: Overview and Challenges. Curr Psychiatry Rep. 2017 Aug; 19(8):48. PMID: 28653117.
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    28. Wierenga CE, Bischoff-Grethe A, Rasmusson G, Bailer UF, Berner LA, Liu TT, Kaye WH. Aberrant Cerebral Blood Flow in Response to Hunger and Satiety in Women Remitted from Anorexia Nervosa. Front Nutr. 2017; 4:32. PMID: 28770207.
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    29. Brown TA, Berner LA, Jones MD, Reilly EE, Cusack A, Anderson LK, Kaye WH, Wierenga CE. Psychometric Evaluation and Norms for the Multidimensional Assessment of Interoceptive Awareness (MAIA) in a Clinical Eating Disorders Sample. Eur Eat Disord Rev. 2017 09; 25(5):411-416. PMID: 28714581.
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    30. Berner LA, Simmons AN, Wierenga CE, Bischoff-Grethe A, Paulus MP, Bailer UF, Ely AV, Kaye WH. Altered interoceptive activation before, during, and after aversive breathing load in women remitted from anorexia nervosa. Psychol Med. 2018 Jan; 48(1):142-154. PMID: 28714434.
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    31. Ely AV, Wierenga CE, Bischoff-Grethe A, Bailer UF, Berner LA, Fudge JL, Paulus MP, Kaye WH. Response in taste circuitry is not modulated by hunger and satiety in women remitted from bulimia nervosa. J Abnorm Psychol. 2017 Jul; 126(5):519-530. PMID: 28691842.
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    32. Maginot TR, Kumar MM, Shiels J, Kaye W, Rhee KE. Outcomes of an inpatient refeeding protocol in youth with anorexia nervosa: Rady Children's Hospital San Diego/University of California, San Diego. J Eat Disord. 2017; 5:1. PMID: 28053702.
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    33. Hill L, Peck SK, Wierenga CE, Kaye WH. Applying neurobiology to the treatment of adults with anorexia nervosa. J Eat Disord. 2016; 4:31. PMID: 27980771.
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    34. Huang JS, Terrones L, Simmons AN, Kaye W, Strigo I. Pilot Study of Functional Magnetic Resonance Imaging Responses to Somatic Pain Stimuli in Youth With Functional and Inflammatory Gastrointestinal Disease. J Pediatr Gastroenterol Nutr. 2016 11; 63(5):500-507. PMID: 27574880.
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    35. Bailer UF, Price JC, Meltzer CC, Wagner A, Mathis CA, Gamst A, Kaye WH. Dopaminergic activity and altered reward modulation in anorexia nervosa-insight from multimodal imaging. Int J Eat Disord. 2017 05; 50(5):593-596. PMID: 27753106.
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    36. Hinney A, Kesselmeier M, Jall S, Volckmar AL, Föcker M, Antel J, Heid IM, Winkler TW, Guo Y, Bergen AW, Kaye W, Berrettini W, Hakonarson H, Herpertz-Dahlmann B, de Zwaan M, Herzog W, Ehrlich S, Zipfel S, Egberts KM, Adan R, Brandys M, van Elburg A, Boraska Perica V, Franklin CS, Tschöp MH, Zeggini E, Bulik CM, Collier D, Scherag A, Müller TD, Hebebrand J. Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index. Mol Psychiatry. 2017 02; 22(2):321-322. PMID: 27457816.
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    37. Hinney A, Kesselmeier M, Jall S, Volckmar AL, Föcker M, Antel J, Heid IM, Winkler TW, Grant SF, Guo Y, Bergen AW, Kaye W, Berrettini W, Hakonarson H, Herpertz-Dahlmann B, de Zwaan M, Herzog W, Ehrlich S, Zipfel S, Egberts KM, Adan R, Brandys M, van Elburg A, Boraska Perica V, Franklin CS, Tschöp MH, Zeggini E, Bulik CM, Collier D, Scherag A, Müller TD, Hebebrand J. Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index. Mol Psychiatry. 2017 02; 22(2):192-201. PMID: 27184124.
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    38. Melrose AJ, Bailer U, Wierenga CE, Bischoff-Grethe A, Paulus MP, Kaye WH. Amphetamine alters neural response to sucrose in healthy women. Psychiatry Res Neuroimaging. 2016 Jun 30; 252:19-25. PMID: 27179312.
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    39. Ely AV, Wierenga CE, Kaye WH. Anxiety Impacts Cognitive Inhibition in Remitted Anorexia Nervosa. Eur Eat Disord Rev. 2016 07; 24(4):347-51. PMID: 27145101.
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    40. Lock J, Agras WS, Bryson SW, Brandt H, Halmi KA, Kaye W, Wilfley D, Woodside B, Pajarito S, Jo B. Does family-based treatment reduce the need for hospitalization in adolescent anorexia nervosa? Int J Eat Disord. 2016 Sep; 49(9):891-4. PMID: 27062400.
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    41. Friedman K, Ramirez AL, Murray SB, Anderson LK, Cusack A, Boutelle KN, Kaye WH. A Narrative Review of Outcome Studies for Residential and Partial Hospital-based Treatment of Eating Disorders. Eur Eat Disord Rev. 2016 07; 24(4):263-76. PMID: 27062687.
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    42. Wagner A, Simmons AN, Oberndorfer TA, Frank GK, McCurdy-McKinnon D, Fudge JL, Yang TT, Paulus MP, Kaye WH. Altered sensitization patterns to sweet food stimuli in patients recovered from anorexia and bulimia nervosa. Psychiatry Res. 2015 Dec 30; 234(3):305-13. PMID: 26596520.
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    43. Compan V, Walsh BT, Kaye W, Geliebter A. How Does the Brain Implement Adaptive Decision Making to Eat? J Neurosci. 2015 Oct 14; 35(41):13868-78. PMID: 26468187.
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    44. Lavender JM, Wonderlich SA, Engel SG, Gordon KH, Kaye WH, Mitchell JE. Dimensions of emotion dysregulation in anorexia nervosa and bulimia nervosa: A conceptual review of the empirical literature. Clin Psychol Rev. 2015 Aug; 40:111-22. PMID: 26112760.
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    45. Knatz S, Wierenga CE, Murray SB, Hill L, Kaye WH. Neurobiologically informed treatment for adults with anorexia nervosa: a novel approach to a chronic disorder. Dialogues Clin Neurosci. 2015 Jun; 17(2):229-36. PMID: 26246796.
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    46. Anderson LK, Murray SB, Ramirez AL, Rockwell R, Le Grange D, Kaye WH. The Integration of Family-Based Treatment and Dialectical Behavior Therapy for Adolescent Bulimia Nervosa: Philosophical and Practical Considerations. Eat Disord. 2015; 23(4):325-35. PMID: 26009868.
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    47. Murray SB, Anderson LK, Rockwell R, Griffiths S, Le Grange D, Kaye WH. Adapting Family-Based Treatment for Adolescent Anorexia Nervosa Across Higher Levels of Patient Care. Eat Disord. 2015; 23(4):302-14. PMID: 26011736.
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    48. Murray SB, Anderson LK, Cusack A, Nakamura T, Rockwell R, Griffiths S, Kaye WH. Integrating Family-Based Treatment and Dialectical Behavior Therapy for Adolescent Bulimia Nervosa: Preliminary Outcomes of an Open Pilot Trial. Eat Disord. 2015; 23(4):336-44. PMID: 26009971.
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    49. Knatz S, Murray SB, Matheson B, Boutelle KN, Rockwell R, Eisler I, Kaye WH. A Brief, Intensive Application of Multi-Family-Based Treatment for Eating Disorders. Eat Disord. 2015; 23(4):315-24. PMID: 25984656.
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    209. La Via MC, Gray N, Kaye WH. Case reports of olanzapine treatment of anorexia nervosa. Int J Eat Disord. 2000 Apr; 27(3):363-6. PMID: 10694725.
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    210. Matsunaga H, Kiriike N, Iwasaki Y, Miyata A, Matsui T, Nagata T, Yamagami S, Kaye WH. Multi-impulsivity among bulimic patients in Japan. Int J Eat Disord. 2000 Apr; 27(3):348-52. PMID: 10694722.
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    211. Strober M, Freeman R, Lampert C, Diamond J, Kaye W. Controlled family study of anorexia nervosa and bulimia nervosa: evidence of shared liability and transmission of partial syndromes. Am J Psychiatry. 2000 Mar; 157(3):393-401. PMID: 10698815.
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    212. Kaye WH, Gendall KA, Fernstrom MH, Fernstrom JD, McConaha CW, Weltzin TE. Effects of acute tryptophan depletion on mood in bulimia nervosa. Biol Psychiatry. 2000 Jan 15; 47(2):151-7. PMID: 10664832.
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    213. Kaye WH, Klump KL, Frank GK, Strober M. Anorexia and bulimia nervosa. Annu Rev Med. 2000; 51:299-313. PMID: 10774466.
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    214. Matsunaga H, Kiriike N, Miyata A, Iwasaki Y, Matsui T, Fujimoto K, Kasai S, Kaye WH. Prevalence and symptomatology of comorbid obsessive-compulsive disorder among bulimic patients. Psychiatry Clin Neurosci. 1999 Dec; 53(6):661-6. PMID: 10687747.
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    215. von Ranson KM, Kaye WH, Weltzin TE, Rao R, Matsunaga H. Obsessive-compulsive disorder symptoms before and after recovery from bulimia nervosa. Am J Psychiatry. 1999 Nov; 156(11):1703-8. PMID: 10553732.
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    216. Kaye WH, Frank GK, McConaha C. Altered dopamine activity after recovery from restricting-type anorexia nervosa. Neuropsychopharmacology. 1999 Oct; 21(4):503-6. PMID: 10481833.
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    217. Stein D, Lilenfeld LR, Plotnicov K, Pollice C, Rao R, Strober M, Kaye WH. Familial aggregation of eating disorders: results from a controlled family study of bulimia nervosa. Int J Eat Disord. 1999 Sep; 26(2):211-5. PMID: 10422611.
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    218. Matsunaga H, Kaye WH, McConaha C, Plotnicov K, Pollice C, Rao R, Stein D. Psychopathological characteristics of recovered bulimics who have a history of physical or sexual abuse. J Nerv Ment Dis. 1999 Aug; 187(8):472-7. PMID: 10463064.
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    219. Gendall KA, Kaye WH, Altemus M, McConaha CW, La Via MC. Leptin, neuropeptide Y, and peptide YY in long-term recovered eating disorder patients. Biol Psychiatry. 1999 Jul 15; 46(2):292-9. PMID: 10418705.
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    220. Kaye W, Strober M, Stein D, Gendall K. New directions in treatment research of anorexia and bulimia nervosa. Biol Psychiatry. 1999 May 15; 45(10):1285-92. PMID: 10349034.
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    221. Sokol MS, Gray NS, Goldstein A, Kaye WH. Methylphenidate treatment for bulimia nervosa associated with a cluster B personality disorder. Int J Eat Disord. 1999 Mar; 25(2):233-7. PMID: 10065402.
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    222. Matsunaga H, Kiriike N, Iwasaki Y, Miyata A, Yamagami S, Kaye WH. Clinical characteristics in patients with anorexia nervosa and obsessive-compulsive disorder. Psychol Med. 1999 Mar; 29(2):407-14. PMID: 10218931.
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    223. Han L, Nielsen DA, Rosenthal NE, Jefferson K, Kaye W, Murphy D, Altemus M, Humphries J, Cassano G, Rotondo A, Virkkunen M, Linnoila M, Goldman D. No coding variant of the tryptophan hydroxylase gene detected in seasonal affective disorder, obsessive-compulsive disorder, anorexia nervosa, and alcoholism. Biol Psychiatry. 1999 Mar 01; 45(5):615-9. PMID: 10088048.
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    224. Deep AL, Lilenfeld LR, Plotnicov KH, Pollice C, Kaye WH. Sexual abuse in eating disorder subtypes and control women: the role of comorbid substance dependence in bulimia nervosa. Int J Eat Disord. 1999 Jan; 25(1):1-10. PMID: 9924647.
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    225. Ferguson CP, La Via MC, Crossan PJ, Kaye WH. Are serotonin selective reuptake inhibitors effective in underweight anorexia nervosa? Int J Eat Disord. 1999 Jan; 25(1):11-7. PMID: 9924648.
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    226. Meltzer CC, Smith G, Price JC, Reynolds CF, Mathis CA, Greer P, Lopresti B, Mintun MA, Pollock BG, Ben-Eliezer D, Cantwell MN, Kaye W, DeKosky ST. Reduced binding of [18F]altanserin to serotonin type 2A receptors in aging: persistence of effect after partial volume correction. Brain Res. 1998 Nov 30; 813(1):167-71. PMID: 9824691.
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    227. Kumar SD, Kumar V, Kaye W. Bilateral internal carotid artery dissection from vomiting. Am J Emerg Med. 1998 Nov; 16(7):669-70. PMID: 9827744.
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    228. Kaye W, Gendall K, Strober M. Serotonin neuronal function and selective serotonin reuptake inhibitor treatment in anorexia and bulimia nervosa. Biol Psychiatry. 1998 Nov 01; 44(9):825-38. PMID: 9807638.
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    229. Kaye WH, Greeno CG, Moss H, Fernstrom J, Fernstrom M, Lilenfeld LR, Weltzin TE, Mann JJ. Alterations in serotonin activity and psychiatric symptoms after recovery from bulimia nervosa. Arch Gen Psychiatry. 1998 Oct; 55(10):927-35. PMID: 9783564.
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    230. Lilenfeld LR, Kaye WH, Greeno CG, Merikangas KR, Plotnicov K, Pollice C, Rao R, Strober M, Bulik CM, Nagy L. A controlled family study of anorexia nervosa and bulimia nervosa: psychiatric disorders in first-degree relatives and effects of proband comorbidity. Arch Gen Psychiatry. 1998 Jul; 55(7):603-10. PMID: 9672050.
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    231. Enoch MA, Kaye WH, Rotondo A, Greenberg BD, Murphy DL, Goldman D. 5-HT2A promoter polymorphism -1438G/A, anorexia nervosa, and obsessive-compulsive disorder. Lancet. 1998 Jun 13; 351(9118):1785-6. PMID: 9635956.
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    232. Kaye WH, Gendall K, Kye C. The role of the central nervous system in the psychoneuroendocrine disturbances of anorexia and bulimia nervosa. Psychiatr Clin North Am. 1998 Jun; 21(2):381-96. PMID: 9670232.
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    233. Nagata T, McConaha C, Rao R, Sokol MS, Kaye WH. A comparison of subgroups of inpatients with anorexia nervosa. Int J Eat Disord. 1997 Nov; 22(3):309-14. PMID: 9285268.
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    234. Lilenfeld LR, Kaye WH, Greeno CG, Merikangas KR, Plotnicov K, Pollice C, Rao R, Strober M, Bulik CM, Nagy L. Psychiatric disorders in women with bulimia nervosa and their first-degree relatives: effects of comorbid substance dependence. Int J Eat Disord. 1997 Nov; 22(3):253-64. PMID: 9285262.
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    235. Chun AB, Sokol MS, Kaye WH, Hutson WR, Wald A. Colonic and anorectal function in constipated patients with anorexia nervosa. Am J Gastroenterol. 1997 Oct; 92(10):1879-83. PMID: 9382057.
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    236. Wisniewski L, Epstein LH, Marcus MD, Kaye W. Differences in salivary habituation to palatable foods in bulimia nervosa patients and controls. Psychosom Med. 1997 Jul-Aug; 59(4):427-33. PMID: 9251163.
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    237. Kaye WH. Persistent alterations in behavior and serotonin activity after recovery from anorexia and bulimia nervosa. Ann N Y Acad Sci. 1997 May 28; 817:162-78. PMID: 9239186.
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    238. Pollice C, Kaye WH, Greeno CG, Weltzin TE. Relationship of depression, anxiety, and obsessionality to state of illness in anorexia nervosa. Int J Eat Disord. 1997 May; 21(4):367-76. PMID: 9138049.
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    239. Kaye WH. Anorexia nervosa, obsessional behavior, and serotonin. Psychopharmacol Bull. 1997; 33(3):335-44. PMID: 9550876.
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    240. Kaye WH, Kaplan AS, Zucker ML. Treating eating-disorder patients in a managed care environment. Contemporary American issues and Canadian response. Psychiatr Clin North Am. 1996 Dec; 19(4):793-810. PMID: 8933609.
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    241. Brennan RT, Braslow A, Batcheller AM, Kaye W. A reliable and valid method for evaluating cardiopulmonary resuscitation training outcomes. Resuscitation. 1996 Sep; 32(2):85-93. PMID: 8896048.
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    242. Kaye WH, Lilenfeld LR, Plotnicov K, Merikangas KR, Nagy L, Strober M, Bulik CM, Moss H, Greeno CG. Bulimia nervosa and substance dependence: association and family transmission. Alcohol Clin Exp Res. 1996 Aug; 20(5):878-81. PMID: 8865963.
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    243. Bircher N, Otto C, Babbs C, Braslow A, Idris A, Keil JP, Kaye W, Lane J, Morioka T, Roese W, Wik L. Future directions for resuscitation research. II. External cardiopulmonary resuscitation basic life support. Resuscitation. 1996 Jul; 32(1):63-75. PMID: 8809921.
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    244. McConaha C, Bastiani AM, Kaye WH. Significant reduction of post-lumbar puncture headaches by the use of a 29-gauge spinal needle. Biol Psychiatry. 1996 Jun 15; 39(12):1058-60. PMID: 8780844.
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    245. Bastiani AM, Altemus M, Pigott TA, Rubenstein C, Weltzin TE, Kaye WH. Comparison of obsessions and compulsions in patients with anorexia nervosa and obsessive compulsive disorder. Biol Psychiatry. 1996 Jun 01; 39(11):966-9. PMID: 9162209.
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    246. Kaye WH. Neuropeptide abnormalities in anorexia nervosa. Psychiatry Res. 1996 Apr 16; 62(1):65-74. PMID: 8739116.
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    247. Kim KY, McCartney JR, Kaye W, Boland RJ, Niaura R. The effect of cimetidine and ranitidine on cognitive function in postoperative cardiac surgical patients. Int J Psychiatry Med. 1996; 26(3):295-307. PMID: 8976470.
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    248. Kaye WH, Wisniewski L. Vulnerability to substance abuse in eating disorders. NIDA Res Monogr. 1996; 159:269-311; discussion 312-21. PMID: 8784862.
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    249. Fernstrom JD, Cameron JL, Fernstrom MH, McConaha C, Weltzin TE, Kaye WH. Short-term neuroendocrine effects of a large oral dose of monosodium glutamate in fasting male subjects. J Clin Endocrinol Metab. 1996 Jan; 81(1):184-91. PMID: 8550750.
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    250. Srinivasagam NM, Kaye WH, Plotnicov KH, Greeno C, Weltzin TE, Rao R. Persistent perfectionism, symmetry, and exactness after long-term recovery from anorexia nervosa. Am J Psychiatry. 1995 Nov; 152(11):1630-4. PMID: 7485626.
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    251. Kaye WH, Bastiani AM, Moss H. Cognitive style of patients with anorexia nervosa and bulimia nervosa. Int J Eat Disord. 1995 Nov; 18(3):287-90. PMID: 8556025.
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    252. Weltzin TE, Fernstrom MH, Fernstrom JD, Neuberger SK, Kaye WH. Acute tryptophan depletion and increased food intake and irritability in bulimia nervosa. Am J Psychiatry. 1995 Nov; 152(11):1668-71. PMID: 7485633.
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    253. Kaye W, Mancini ME, Richards N. Organizing and implementing a hospital-wide first-responder automated external defibrillation program: strengthening the in-hospital chain of survival. Resuscitation. 1995 Oct; 30(2):151-6. PMID: 8560104.
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    254. Baran SA, Weltzin TE, Kaye WH. Low discharge weight and outcome in anorexia nervosa. Am J Psychiatry. 1995 Jul; 152(7):1070-2. PMID: 7793445.
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    255. Neuberger SK, Rao R, Weltzin TE, Greeno C, Kaye WH. Differences in weight gain between restrictor and bulimic anorectics. Int J Eat Disord. 1995 May; 17(4):331-5. PMID: 7620472.
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    256. Bulik CM, Sullivan PF, Weltzin TE, Kaye WH. Temperament in eating disorders. Int J Eat Disord. 1995 Apr; 17(3):251-61. PMID: 7773262.
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    257. Deep AL, Nagy LM, Weltzin TE, Rao R, Kaye WH. Premorbid onset of psychopathology in long-term recovered anorexia nervosa. Int J Eat Disord. 1995 Apr; 17(3):291-7. PMID: 7773266.
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    258. Bastiani AM, Rao R, Weltzin T, Kaye WH. Perfectionism in anorexia nervosa. Int J Eat Disord. 1995 Mar; 17(2):147-52. PMID: 7757095.
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    259. Weltzin TE, Bulik CM, McConaha CW, Kaye WH. Laxative withdrawal and anxiety in bulimia nervosa. Int J Eat Disord. 1995 Mar; 17(2):141-6. PMID: 7757094.
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    260. Kaye W, Mancini ME, Giuliano KK, Richards N, Nagid DM, Marler CA, Sawyer-Silva S. Strengthening the in-hospital chain of survival with rapid defibrillation by first responders using automated external defibrillators: training and retention issues. Ann Emerg Med. 1995 Feb; 25(2):163-8. PMID: 7832341.
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    261. Weltzin TE, Fernstrom MH, Kaye WH. Serotonin and bulimia nervosa. Nutr Rev. 1994 Dec; 52(12):399-408. PMID: 7898781.
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    262. Fernstrom MH, Weltzin TE, Neuberger S, Srinivasagam N, Kaye WH. Twenty-four-hour food intake in patients with anorexia nervosa and in healthy control subjects. Biol Psychiatry. 1994 Nov 15; 36(10):696-702. PMID: 7880939.
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    263. Sullivan PF, Bulik CM, Hall S, Weltzin TE, Kaye WH. Defense style in women with eating disorders. Int J Eat Disord. 1994 Nov; 16(3):251-6. PMID: 7833958.
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    264. Weltzin TE, Fernstrom JD, McConaha C, Kaye WH. Acute tryptophan depletion in bulimia: effects on large neutral amino acids. Biol Psychiatry. 1994 Mar 15; 35(6):388-97. PMID: 8018785.
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    265. Weltzin TE, McCabe E, Flynn D, Kaye W. Anorexia and bulimia nervosa: psychiatric approach. Curr Ther Endocrinol Metab. 1994; 5:15-21. PMID: 7704702.
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    266. Lesem MD, Kaye WH, Bissette G, Jimerson DC, Nemeroff CB. Cerebrospinal fluid TRH immunoreactivity in anorexia nervosa. Biol Psychiatry. 1994 Jan 01; 35(1):48-53. PMID: 8167204.
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    267. Weltzin TE, Cameron J, Berga S, Kaye WH. Prediction of reproductive status in women with bulimia nervosa by past high weight. Am J Psychiatry. 1994 Jan; 151(1):136-8. PMID: 8267113.
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    268. Bulik CM, Sullivan PF, McKee M, Weltzin TE, Kaye WH. Characteristics of bulimic women with and without alcohol abuse. Am J Drug Alcohol Abuse. 1994; 20(2):273-83. PMID: 8042608.
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    269. Hsu LK, Kaye W, Weltzin T. Are the eating disorders related to obsessive compulsive disorder? Int J Eat Disord. 1993 Nov; 14(3):305-18. PMID: 8275067.
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    270. Kaye WH, Weltzin TE, Hsu LK, McConaha CW, Bolton B. Amount of calories retained after binge eating and vomiting. Am J Psychiatry. 1993 Jun; 150(6):969-71. PMID: 8494080.
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    271. Groeger JS, Guntupalli KK, Strosberg M, Halpern N, Raphaely RC, Cerra F, Kaye W. Descriptive analysis of critical care units in the United States: patient characteristics and intensive care unit utilization. Crit Care Med. 1993 Feb; 21(2):279-91. PMID: 8428482.
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    272. Bulik CM, Beidel DC, Duchmann E, Weltzin TE, Kaye WH. Comparative psychopathology of women with bulimia nervosa and obsessive-compulsive disorder. Compr Psychiatry. 1992 Jul-Aug; 33(4):262-8. PMID: 1643868.
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    273. Kaye WH, Weltzin TE, McKee M, McConaha C, Hansen D, Hsu LK. Laboratory assessment of feeding behavior in bulimia nervosa and healthy women: methods for developing a human-feeding laboratory. Am J Clin Nutr. 1992 Feb; 55(2):372-80. PMID: 1734674.
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    274. Jimerson DC, Lesem MD, Kaye WH, Brewerton TD. Low serotonin and dopamine metabolite concentrations in cerebrospinal fluid from bulimic patients with frequent binge episodes. Arch Gen Psychiatry. 1992 Feb; 49(2):132-8. PMID: 1372494.
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    275. Kaye WH, Weltzin TE. Serotonin activity in anorexia and bulimia nervosa: relationship to the modulation of feeding and mood. J Clin Psychiatry. 1991 Dec; 52 Suppl:41-8. PMID: 1752859.
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    276. Weltzin TE, Hsu LK, Pollice C, Kaye WH. Feeding patterns in bulimia nervosa. Biol Psychiatry. 1991 Dec 01; 30(11):1093-110. PMID: 1777527.
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    277. Weltzin TE, Fernstrom MH, Hansen D, McConaha C, Kaye WH. Abnormal caloric requirements for weight maintenance in patients with anorexia and bulimia nervosa. Am J Psychiatry. 1991 Dec; 148(12):1675-82. PMID: 1957930.
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    278. Kaye WH, Weltzin TE, Hsu LK, Bulik CM. An open trial of fluoxetine in patients with anorexia nervosa. J Clin Psychiatry. 1991 Nov; 52(11):464-71. PMID: 1744064.
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    279. Kaye WH, Weltzin TE. Neurochemistry of bulimia nervosa. J Clin Psychiatry. 1991 Oct; 52 Suppl:21-8. PMID: 1682306.
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    280. Weltzin TE, McConaha C, McKee M, Hsu LK, Perel J, Kaye WH. Circadian patterns of cortisol, prolactin, and growth hormonal secretion during bingeing and vomiting in normal weight bulimic patients. Biol Psychiatry. 1991 Jul 01; 30(1):37-48. PMID: 1892960.
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    281. Cameron JL, Weltzin TE, McConaha C, Helmreich DL, Kaye WH. Slowing of pulsatile luteinizing hormone secretion in men after forty-eight hours of fasting. J Clin Endocrinol Metab. 1991 Jul; 73(1):35-41. PMID: 1904451.
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    282. Kaye WH, Gwirtsman HE, George DT, Ebert MH. Altered serotonin activity in anorexia nervosa after long-term weight restoration. Does elevated cerebrospinal fluid 5-hydroxyindoleacetic acid level correlate with rigid and obsessive behavior? Arch Gen Psychiatry. 1991 Jun; 48(6):556-62. PMID: 1710099.
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    283. Kaye W, Rallis SF, Mancini ME, Linhares KC, Angell ML, Donovan DS, Zajano NC, Finger JA. The problem of poor retention of cardiopulmonary resuscitation skills may lie with the instructor, not the learner or the curriculum. Resuscitation. 1991 Feb; 21(1):67-87. PMID: 1852067.
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    284. Lesem MD, Berrettini WH, Kaye WH, Jimerson DC. Measurement of CSF dynorphin A 1-8 immunoreactivity in anorexia nervosa and normal-weight bulimia. Biol Psychiatry. 1991 Feb 01; 29(3):244-52. PMID: 1673064.
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    285. Jimerson DC, Lesem MD, Kaye WH, Hegg AP, Brewerton TD. Eating disorders and depression: is there a serotonin connection? Biol Psychiatry. 1990 Sep 01; 28(5):443-54. PMID: 2207221.
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    286. George DT, Kaye WH, Goldstein DS, Brewerton TD, Jimerson DC. Altered norepinephrine regulation in bulimia: effects of pharmacological challenge with isoproterenol. Psychiatry Res. 1990 Jul; 33(1):1-10. PMID: 2171006.
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    287. Kaye WH, Berrettini W, Gwirtsman H, George DT. Altered cerebrospinal fluid neuropeptide Y and peptide YY immunoreactivity in anorexia and bulimia nervosa. Arch Gen Psychiatry. 1990 Jun; 47(6):548-56. PMID: 2350207.
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    288. Kaye WH, Ballenger JC, Lydiard RB, Stuart GW, Laraia MT, O'Neil P, Fossey MD, Stevens V, Lesser S, Hsu G. CSF monoamine levels in normal-weight bulimia: evidence for abnormal noradrenergic activity. Am J Psychiatry. 1990 Feb; 147(2):225-9. PMID: 1689122.
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    289. Bulik CM, Epstein LH, Kaye W. Treatment of laxative abuse in a female with bulimia nervosa using an operant extinction paradigm. J Subst Abuse. 1990; 2(3):381-8. PMID: 2136123.
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    290. Kaye WH, George DT, Gwirtsman HE, Jimerson DC, Goldstein DS, Ebert MH, Lake CR. Isoproterenol infusion test in anorexia nervosa: assessment of pre- and post-beta-noradrenergic receptor activity. Psychopharmacol Bull. 1990; 26(3):355-9. PMID: 2274636.
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    291. Bulik CM, Epstein LH, McKee M, Kaye W. Drug use in women with bulimia and anorexia nervosa. NIDA Res Monogr. 1990; 105:462-3. PMID: 1876079.
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    292. Kaye WH, Gwirtsman HE, George DT, Jimerson DC, Ebert MH, Lake CR. Disturbances of noradrenergic systems in normal weight bulimia: relationship to diet and menses. Biol Psychiatry. 1990 Jan 01; 27(1):4-21. PMID: 2297551.
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    293. Gwirtsman HE, Kaye WH, George DT, Carosella NW, Greene RC, Jimerson DC. Hyperamylasemia and its relationship to binge-purge episodes: development of a clinically relevant laboratory test. J Clin Psychiatry. 1989 Jun; 50(6):196-204. PMID: 2470728.
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    294. Kaye WH, Gwirtsman HE, George DT. The effect of bingeing and vomiting on hormonal secretion. Biol Psychiatry. 1989 Mar 15; 25(6):768-80. PMID: 2647157.
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    295. Lesem MD, George DT, Kaye WH, Goldstein DS, Jimerson DC. State-related changes in norepinephrine regulation in anorexia nervosa. Biol Psychiatry. 1989 Feb 15; 25(4):509-12. PMID: 2930816.
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    296. Gwirtsman HE, Kaye WH, Obarzanek E, George DT, Jimerson DC, Ebert MH. Decreased caloric intake in normal-weight patients with bulimia: comparison with female volunteers. Am J Clin Nutr. 1989 Jan; 49(1):86-92. PMID: 2912015.
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    297. Gwirtsman HE, Kaye WH, George DT, Jimerson DC, Ebert MH, Gold PW. Central and peripheral ACTH and cortisol levels in anorexia nervosa and bulimia. Arch Gen Psychiatry. 1989 Jan; 46(1):61-9. PMID: 2535925.
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    298. Gwirtsman HE, Kaye WH, Curtis SR, Lyter LM. Energy intake and dietary macronutrient content in women with anorexia nervosa and volunteers. J Am Diet Assoc. 1989 Jan; 89(1):54-7. PMID: 2909592.
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    299. Kaye WH, Berrettini WH, Gwirtsman HE, Gold PW, George DT, Jimerson DC, Ebert MH. Contribution of CNS neuropeptide (NPY, CRH, and beta-endorphin) alterations to psychophysiological abnormalities in anorexia nervosa. Psychopharmacol Bull. 1989; 25(3):433-8. PMID: 2533990.
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    300. Bulik CM, Dahl R, Epstein LH, Kaye W. The effects of smoking deprivation on caloric consumption in women with bulimia nervosa. NIDA Res Monogr. 1989; 95:429-30. PMID: 2701311.
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    301. Kassett JA, Gwirtsman HE, Kaye WH, Brandt HA, Jimerson DC. Pattern of onset of bulimic symptoms in anorexia nervosa. Am J Psychiatry. 1988 Oct; 145(10):1287-8. PMID: 3421352.
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    302. Kaye WH, Gwirtsman HE, Obarzanek E, George DT. Relative importance of calorie intake needed to gain weight and level of physical activity in anorexia nervosa. Am J Clin Nutr. 1988 Jun; 47(6):989-94. PMID: 3376913.
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    303. Kaye W, Bircher NG. Access for drug administration during cardiopulmonary resuscitation. Crit Care Med. 1988 Feb; 16(2):179-82. PMID: 3342630.
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    304. Berrettini WH, Kaye WH, Sunderland T, May C, Gwirtsman HE, Mellow A, Albright A. Galanin immunoreactivity in human CSF: studies in eating disorders and Alzheimer's disease. Neuropsychobiology. 1988; 19(2):64-8. PMID: 2465504.
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    305. Kaye WH, Gwirtsman HE, Brewerton TD, George DT, Wurtman RJ. Bingeing behavior and plasma amino acids: a possible involvement of brain serotonin in bulimia nervosa. Psychiatry Res. 1988 Jan; 23(1):31-43. PMID: 2834764.
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    306. Kaye WH, Gwirtsman HE, George DT, Jimerson DC, Ebert MH. CSF 5-HIAA concentrations in anorexia nervosa: reduced values in underweight subjects normalize after weight gain. Biol Psychiatry. 1988 Jan 01; 23(1):102-5. PMID: 2447961.
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    307. Kaye WH, Rubinow D, Gwirtsman HE, George DT, Jimerson DC, Gold PW. CSF somatostatin in anorexia nervosa and bulimia: relationship to the hypothalamic pituitary-adrenal cortical axis. Psychoneuroendocrinology. 1988; 13(3):265-72. PMID: 2900533.
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    308. Berrettini WH, Kaye WH, Gwirtsman H, Allbright A. Cerebrospinal fluid peptide YY immunoreactivity in eating disorders. Neuropsychobiology. 1988; 19(3):121-4. PMID: 3200408.
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    309. Kaye WH, Berrettini WH, Gwirtsman HE, Chretien M, Gold PW, George DT, Jimerson DC, Ebert MH. Reduced cerebrospinal fluid levels of immunoreactive pro-opiomelanocortin related peptides (including beta-endorphin) in anorexia nervosa. Life Sci. 1987 Nov 02; 41(18):2147-55. PMID: 2823041.
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    310. Moley JF, Aamodt R, Rumble W, Kaye W, Norton JA. Body cell mass in cancer-bearing and anorexic patients. JPEN J Parenter Enteral Nutr. 1987 May-Jun; 11(3):219-22. PMID: 3474427.
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    311. Kaye WH, Gwirtsman HE, George DT, Ebert MH, Jimerson DC, Tomai TP, Chrousos GP, Gold PW. Elevated cerebrospinal fluid levels of immunoreactive corticotropin-releasing hormone in anorexia nervosa: relation to state of nutrition, adrenal function, and intensity of depression. J Clin Endocrinol Metab. 1987 Feb; 64(2):203-8. PMID: 3491830.
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    312. Duncan CC, Kaye WH. Effects of clonidine on event-related potential measures of information processing. Electroencephalogr Clin Neurophysiol Suppl. 1987; 40:527-31. PMID: 3480173.
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    313. Kaye WH, Gwirtsman HE, George DT, Weiss SR, Jimerson DC. Relationship of mood alterations to bingeing behaviour in bulimia. Br J Psychiatry. 1986 Oct; 149:479-85. PMID: 3814933.
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    314. Kaye WH, Gwirtsman HE, Obarzanek E, George T, Jimerson DC, Ebert MH. Caloric intake necessary for weight maintenance in anorexia nervosa: nonbulimics require greater caloric intake than bulimics. Am J Clin Nutr. 1986 Oct; 44(4):435-43. PMID: 3766430.
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    315. Uhde TW, Vittone BJ, Siever LJ, Kaye WH, Post RM. Blunted growth hormone response to clonidine in panic disorder patients. Biol Psychiatry. 1986 Sep; 21(11):1081-5. PMID: 3741921.
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    316. Gold PW, Gwirtsman H, Avgerinos PC, Nieman LK, Gallucci WT, Kaye W, Jimerson D, Ebert M, Rittmaster R, Loriaux DL. Abnormal hypothalamic-pituitary-adrenal function in anorexia nervosa. Pathophysiologic mechanisms in underweight and weight-corrected patients. N Engl J Med. 1986 May 22; 314(21):1335-42. PMID: 3010109.
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    317. Petersen R, Kaye WH, Gwirtsman HE. Comparison of calculated estimates and laboratory analysis of food offered to hospitalized eating disorder patients. J Am Diet Assoc. 1986 Apr; 86(4):490-2. PMID: 3958399.
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    318. Strupp BJ, Weingartner H, Kaye W, Gwirtsman H. Cognitive processing in anorexia nervosa. A disturbance in automatic information processing. Neuropsychobiology. 1986; 15(2):89-94. PMID: 3762904.
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    319. Winterer J, Gwirtsman HE, George DT, Kaye WH, Loriaux DL, Cutler GB. Adrenocorticotropin-stimulated adrenal androgen secretion in anorexia nervosa: impaired secretion at low weight with normalization after long-term weight recovery. J Clin Endocrinol Metab. 1985 Oct; 61(4):693-7. PMID: 2993344.
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    320. Kaye WH, Jimerson DC, Lake CR, Ebert MH. Altered norepinephrine metabolism following long-term weight recovery in patients with anorexia nervosa. Psychiatry Res. 1985 Apr; 14(4):333-42. PMID: 3860886.
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    321. Kaye WH. Eating disorders: too little or too much. Biol Psychiatry. 1985 Mar; 20(3):233-4. PMID: 3856456.
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    322. Siever LJ, Uhde TW, Insel TR, Kaye WH, Jimerson DC, Lake CR, Kafka M, Targum S, Murphy DL. Biological alterations in the primary affective disorders and other tricyclic-responsive disorders. Prog Neuropsychopharmacol Biol Psychiatry. 1985; 9(1):15-24. PMID: 2986198.
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    323. Kaye WH, Gwirtsman HE, Lake CR, Siever LJ, Jimerson DC, Ebert MH, Murphy DL. Disturbances of norepinephrine metabolism and alpha-2 adrenergic receptor activity in anorexia nervosa: relationship to nutritional state. Psychopharmacol Bull. 1985; 21(3):419-23. PMID: 2994154.
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    324. Kaye WH, Ebert MH, Gwirtsman HE, Weiss SR. Differences in brain serotonergic metabolism between nonbulimic and bulimic patients with anorexia nervosa. Am J Psychiatry. 1984 Dec; 141(12):1598-601. PMID: 6209991.
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    325. Gwirtsman H, Kaye W, Weintraub M, Jimerson DC. Pharmacologic treatment of eating disorders. Psychiatr Clin North Am. 1984 Dec; 7(4):863-78. PMID: 6151652.
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    326. Gershon ES, Schreiber JL, Hamovit JR, Dibble ED, Kaye W, Nurnberger JI, Andersen AE, Ebert M. Clinical findings in patients with anorexia nervosa and affective illness in their relatives. Am J Psychiatry. 1984 Nov; 141(11):1419-22. PMID: 6496786.
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    327. Kaye WH, Ebert MH, Raleigh M, Lake R. Abnormalities in CNS monoamine metabolism in anorexia nervosa. Arch Gen Psychiatry. 1984 Apr; 41(4):350-5. PMID: 6200083.
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    328. Gold PW, Robertson GL, Ballenger JC, Kaye W, Chen J, Rubinow DR, Goodwin FK, Post RM. Carbamazepine diminishes the sensitivity of the plasma arginine vasopressin response to osmotic stimulation. J Clin Endocrinol Metab. 1983 Nov; 57(5):952-7. PMID: 6619270.
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    329. Gross H, Ebert MH, Faden VB, Goldberg SC, Kaye WH, Caine ED, Hawks R, Zinberg N. A double-blind trial of delta 9-tetrahydrocannabinol in primary anorexia nervosa. J Clin Psychopharmacol. 1983 Jun; 3(3):165-71. PMID: 6308069.
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    330. Gold PW, Kaye W, Robertson GL, Ebert M. Abnormalities in plasma and cerebrospinal-fluid arginine vasopressin in patients with anorexia nervosa. N Engl J Med. 1983 May 12; 308(19):1117-23. PMID: 6835335.
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    331. Siever LJ, Uhde TW, Insel TR, Kaye WH, Jimerson DC, Lake CR, Kafka M, Targum S, Murphy L. Abnormalities in the primary affective disorders compared to other tricyclic-responsive disorders. Psychopharmacol Bull. 1983; 19(3):435-6. PMID: 6635119.
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    332. Kaye WH, Pickar D, Naber D, Ebert MH. Cerebrospinal fluid opioid activity in anorexia nervosa. Am J Psychiatry. 1982 May; 139(5):643-5. PMID: 7072853.
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    333. Kaye WH, Sitaram N, Weingartner H, Ebert MH, Smallberg S, Gillin JC. Modest facilitation on memory in dementia with combined lecithin and anticholinerestase treatment. Biol Psychiatry. 1982 Feb; 17(2):275-80. PMID: 7074185.
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    334. Weingartner H, Cohen RM, Bunney WE, Ebert MH, Kaye W. Memory-learning impairments in progressive dementia and depression. Am J Psychiatry. 1982 Jan; 139(1):135-6. PMID: 7055267.
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    335. Pickar D, Naber D, Post RM, van Kammen DP, Kaye W, Rubinow DR, Ballenger JC, Bunney WE. Endorphins in the cerebrospinal fluid of psychiatric patients. Ann N Y Acad Sci. 1982; 398:399-412. PMID: 6297360.
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    336. Gross HA, Ebert MH, Faden VB, Goldberg SC, Nee LE, Kaye WH. A double-blind controlled trial of lithium carbonate primary anorexia nervosa. J Clin Psychopharmacol. 1981 Nov; 1(6):376-81. PMID: 6801096.
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    337. Weingartner H, Kaye W, Smallberg SA, Ebert MH, Gillin JC, Sitaram N. Memory failures in progressive idiopathic dementia. J Abnorm Psychol. 1981 Jun; 90(3):187-96. PMID: 7288013.
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    338. Ehrlich BE, Diamond JM, Kaye W, Ornitz EM, Gosenfeld L. Lithium transport in erythrocytes from a pair of twins with manic disorder. Am J Psychiatry. 1979 Nov; 136(11):1477-8. PMID: 495808.
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