Rohit Loomba

Title(s)Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Biography 
    Collapse Education and Training
    The Armed Forces Medical College, IndiaMBBS (MD)1999Medicine
    St. Luke's HospitalResidency, Chief Resident2004Medicine
    NIH/NIDDK, BethesdaFellowship2007Hepatology
    UC San DiegoFellowship2009Gastroenterology

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Non-invasive screening of diabetics for advanced fibrosis due to NAFLD
    NIH/NIDDK R01DK124318May 20, 2020 - Apr 30, 2023
    Role: Principal Investigator
    Ancillary Studies of NAFLD and NASH in HIV infected Adults
    NIH/NIDDK R01DK121378Mar 21, 2020 - Jan 31, 2025
    Role: Co-Principal Investigator
    QUS Technology for Diagnosis and Grading of Hepatic Steatosis in NAFLD
    NIH R01DK106419Jul 1, 2015 - May 31, 2021
    Role: Principal Investigator
    GENETIC EPIDEMIOLOGY OF NONALCOHOLIC FATTY LIVER DISEASE
    NIH/NIDDK K23DK090303Sep 15, 2011 - Aug 31, 2015
    Role: Principal Investigator
    Clinical Research on Nonalcoholic Fatty Liver Disease
    NIH/NIDDK U01DK061734Sep 15, 2002 - Jun 30, 2024
    Role: Co-Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A prospective study on the prevalence of at-risk MASH in patients with type 2 diabetes mellitus in the United States. Aliment Pharmacol Ther. 2024 Apr 08. Mittal N, Siddiqi H, Madamba E, Richards L, Bettencourt R, Ajmera V, Loomba R. PMID: 38586922.
      View in: PubMed   Mentions:
    2. New and emerging treatments for metabolic dysfunction-associated steatohepatitis. Cell Metab. 2024 Apr 07. Tincopa MA, Anstee QM, Loomba R. PMID: 38608696.
      View in: PubMed   Mentions:
    3. Natural history of clinical outcomes and hepatic decompensation in metabolic dysfunction-associated steatotic liver disease. Aliment Pharmacol Ther. 2024 Apr 03. Noureddin N, Huang DQ, Bettencourt R, Siddiqi H, Majzoub AM, Nayfeh T, Tamaki N, Izumi N, Nakajima A, Idilman R, Gumussoy M, Oz DK, Erden A, Gidener T, Allen AM, Ajmera V, Loomba R. PMID: 38571305.
      View in: PubMed   Mentions:    Fields:    
    4. Review article: New developments in biomarkers and clinical drug development in alpha-1 antitrypsin deficiency-related liver disease. Aliment Pharmacol Ther. 2024 Mar 22. Loomba R, Clark G, Teckman J, Ajmera V, Behling C, Brantly M, Brenner D, D'Armiento J, Fried MW, Iyer JS, Mandorfer M, Rockey DC, Tincopa M, Vuppalanchi R, Younossi Z, Krag A, Turner AM, Strnad P. PMID: 38516814.
      View in: PubMed   Mentions:    Fields:    
    5. MASH Resolution Index: development and validation of a non-invasive score to detect histological resolution of MASH. Gut. 2024 Feb 28. Loomba R, Amangurbanova M, Bettencourt R, Madamba E, Siddiqi H, Richards L, Behling C, Sirlin CB, Gottwald MD, Feng S, Margalit M, Huang DQ. PMID: 38418210.
      View in: PubMed   Mentions:    Fields:    
    6. From NAFLD to MASLD: implications of the new nomenclature for preclinical and clinical research. Nat Metab. 2024 Feb 21. Hsu CL, Loomba R. PMID: 38383845.
      View in: PubMed   Mentions:    Fields:    
    7. A Phase 3, Randomized, Controlled Trial of Resmetirom in NASH with Liver Fibrosis. N Engl J Med. 2024 02 08; 390(6):497-509. Harrison SA, Bedossa P, Guy CD, Schattenberg JM, Loomba R, Taub R, Labriola D, Moussa SE, Neff GW, Rinella ME, Anstee QM, Abdelmalek MF, Younossi Z, Baum SJ, Francque S, Charlton MR, Newsome PN, Lanthier N, Schiefke I, Mangia A, Pericàs JM, Patil R, Sanyal AJ, Noureddin M, Bansal MB, Alkhouri N, Castera L, Rudraraju M, Ratziu V, MAESTRO-NASH Investigators. PMID: 38324483.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    8. Reply. Clin Gastroenterol Hepatol. 2024 Feb 02. Loomba R, Zamani M. PMID: 38311149.
      View in: PubMed   Mentions:    Fields:    
    9. Implications of the new nomenclature of steatotic liver disease and definition of metabolic dysfunction-associated steatotic liver disease. Aliment Pharmacol Ther. 2024 Jan; 59(2):150-156. Loomba R, Wong VW. PMID: 38153279; PMCID: PMC10807722.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    10. Letter: Are we forgetting the importance of steatosis in steatotic liver disease? Authors' reply. Aliment Pharmacol Ther. 2024 Jan; 59(2):297-298. Kuo SZ, Loomba R. PMID: 38153275.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. Diagnosis and Monitoring of Nonalcoholic Steatohepatitis: Current State and Future Directions. Radiology. 2024 Jan; 310(1):e222695. Kadi D, Loomba R, Bashir MR. PMID: 38226882.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Randomized Trial of Pegozafermin in NASH. Reply. N Engl J Med. 2023 Dec 07; 389(23):2210. Loomba R, Mansbach H, Margalit M. PMID: 38055266.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Low liver fat in non-alcoholic steatohepatitis-related significant fibrosis and cirrhosis is associated with hepatocellular carcinoma, decompensation and mortality. Aliment Pharmacol Ther. 2024 Jan; 59(1):80-88. Lee SW, Huang DQ, Bettencourt R, Ajmera V, Tincopa M, Noureddin N, Amangurbanova M, Siddiqi H, Madamba E, Majzoub AM, Nayfeh T, Tamaki N, Izumi N, Nakajima A, Yoneda M, Idilman R, Gumussoy M, Oz DK, Erden A, Loomba R. PMID: 37968251; PMCID: PMC10807727.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. Editorial: Can liver fat quantification stratify cardiovascular risk in type 2 diabetes? Authors' reply. Aliment Pharmacol Ther. 2023 11; 58(10):1109-1110. Kuo SZ, Loomba R. PMID: 37885163.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. Validation of AGA clinical care pathway and AASLD practice guidance for nonalcoholic fatty liver disease in a prospective cohort of patients with type 2 diabetes. Hepatology. 2023 Oct 20. Ajmera V, Tesfai K, Sandoval E, Lopez S, Cervantes V, Madamba E, Bettencourt R, Manousou P, Richards L, Loomba R. PMID: 37862551.
      View in: PubMed   Mentions:    Fields:    
    16. Repeatability of MRI Biomarkers in Nonalcoholic Fatty Liver Disease: The NIMBLE Consortium. Radiology. 2023 10; 309(1):e231092. Fowler KJ, Venkatesh SK, Obuchowski N, Middleton MS, Chen J, Pepin K, Magnuson J, Brown KJ, Batakis D, Henderson WC, Shankar SS, Kamphaus TN, Pasek A, Calle RA, Sanyal AJ, Loomba R, Ehman R, Samir AE, Sirlin CB, Sherlock SP. PMID: 37815451; PMCID: PMC10625902.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    17. MEFIB-Index and MAST-Score in the assessment of hepatic decompensation in metabolic dysfunction-associated steatosis liver disease-Individual participant data meta-analyses. Aliment Pharmacol Ther. 2023 11; 58(9):856-865. Noureddin N, Ajmera V, Bergstrom J, Bettencourt R, Huang DQ, Siddiqi H, Majzoub AM, Nayfeh T, Tamaki N, Izumi N, Nakajima A, Idilman R, Gumussoy M, Oz DK, Erden A, Loomba R. PMID: 37694993; PMCID: PMC10901230.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    18. Ramipril for the Treatment of COVID-19: RAMIC, a Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Adv Ther. 2023 11; 40(11):4805-4816. Huang DQ, Ajmera V, Tomaszewski C, LaFree A, Bettencourt R, Thompson WK, Smith DM, Malhotra A, Mehta RL, Tolia V, Yin J, Insel PA, Leachman S, Jung J, Collier S, Richards L, Woods K, Amangurbanova M, Bhatt A, Zhang X, Penciu OM, Zarich S, Retta T, Harkins MS, Teixeira JP, Chinnock B, Utay NS, Lake JE, Loomba R. PMID: 37615850; PMCID: PMC10709987.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    19. Editorial: Will MRI-PDFF become the new standard for steatosis assessment in NAFLD? Authors' reply. Aliment Pharmacol Ther. 2023 08; 58(3):366-367. Huang DQ, Loomba R. PMID: 37452591.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. Semaglutide in NASH-related cirrhosis: still a long way to go? - Authors' reply. Lancet Gastroenterol Hepatol. 2023 Aug; 8(8):694-695. Loomba R, Newsome PN. PMID: 37453429.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    21. Reply to: "Non-invasive testing for advanced fibrosis in patients with diabetes with fatty liver disease needs further evaluation of cut-off values". J Hepatol. 2023 Nov; 79(5):e192-e193. Ajmera V, Loomba R. PMID: 37517453.
      View in: PubMed   Mentions:    Fields:    
    22. Clinical utility of liver fat quantification for determining cardiovascular disease risk among patients with type 2 diabetes. Aliment Pharmacol Ther. 2023 09; 58(6):585-592. Kuo SZ, Cepin S, Bergstrom J, Siddiqi H, Jung J, Lopez S, Huang DQ, Taub P, Amangurbanova M, Loomba R. PMID: 37431679; PMCID: PMC10792531.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    23. Type 2 diabetes, hepatic decompensation, and hepatocellular carcinoma in patients with non-alcoholic fatty liver disease: an individual participant-level data meta-analysis. Lancet Gastroenterol Hepatol. 2023 09; 8(9):829-836. Huang DQ, Noureddin N, Ajmera V, Amangurbanova M, Bettencourt R, Truong E, Gidener T, Siddiqi H, Majzoub AM, Nayfeh T, Tamaki N, Izumi N, Yoneda M, Nakajima A, Idilman R, Gumussoy M, Oz DK, Erden A, Allen AM, Noureddin M, Loomba R. PMID: 37419133; PMCID: PMC10812844.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    24. Development and Validation of the Nonalcoholic Fatty Liver Disease Familial Risk Score to Detect Advanced Fibrosis: A Prospective, Multicenter Study. Clin Gastroenterol Hepatol. 2024 01; 22(1):81-90.e4. Huang DQ, Ahlholm N, Luukkonen PK, Porthan K, Amangurbanova M, Madamba E, Bettencourt R, Siddiqi H, Cervantes V, Hernandez C, Lopez SJ, Richards L, Nemes K, Isoniemi H, Yki-Järvinen H, Loomba R. PMID: 37406954.
      View in: PubMed   Mentions: 2     Fields:    
    25. Randomized, Controlled Trial of the FGF21 Analogue Pegozafermin in NASH. N Engl J Med. 2023 Sep 14; 389(11):998-1008. Loomba R, Sanyal AJ, Kowdley KV, Bhatt DL, Alkhouri N, Frias JP, Bedossa P, Harrison SA, Lazas D, Barish R, Gottwald MD, Feng S, Agollah GD, Hartsfield CL, Mansbach H, Margalit M, Abdelmalek MF. PMID: 37356033; PMCID: PMC10718287.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCTClinical Trials
    26. Clinical and histologic factors associated with discordance between steatosis grade derived from histology vs. MRI-PDFF in NAFLD. Aliment Pharmacol Ther. 2023 07; 58(2):229-237. Kim BK, Bernstein N, Huang DQ, Tamaki N, Imajo K, Yoneda M, Sutter N, Jung J, Nguyen K, Nguyen L, Le T, Madamba E, Richards L, Valasek MA, Behling C, Sirlin CB, Nakajima A, Loomba R. PMID: 37269117; PMCID: PMC10330628.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    27. Magnetic resonance elastography-based prediction model for hepatic decompensation in NAFLD: A multicenter cohort study. Hepatology. 2023 Dec 01; 78(6):1858-1866. Kim BK, Bergstrom J, Loomba R, Tamaki N, Izumi N, Nakajima A, Idilman R, Gumussoy M, Oz DK, Erden A, Truong E, Yang JD, Noureddin M, Allen AM, Loomba R, Ajmera V. PMID: 37203233; PMCID: PMC10663382.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    28. Fibrosis Progression Rate in Biopsy-Proven Nonalcoholic Fatty Liver Disease Among People With Diabetes Versus People Without Diabetes: A Multicenter Study. Gastroenterology. 2023 08; 165(2):463-472.e5. Huang DQ, Wilson LA, Behling C, Kleiner DE, Kowdley KV, Dasarathy S, Amangurbanova M, Terrault NA, Diehl AM, Chalasani N, Neuschwander-Tetri BA, Sanyal AJ, Tonascia J, NASH Clinical Research Network, Loomba R. PMID: 37127100; PMCID: PMC10699569.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    29. Pegbelfermin in Patients With Nonalcoholic Steatohepatitis and Stage 3 Fibrosis (FALCON 1): A Randomized Phase 2b Study. Clin Gastroenterol Hepatol. 2024 01; 22(1):102-112.e9. Loomba R, Sanyal AJ, Nakajima A, Neuschwander-Tetri BA, Goodman ZD, Harrison SA, Lawitz EJ, Gunn N, Imajo K, Ravendhran N, Akahane T, Boone B, Yamaguchi M, Chatterjee A, Tirucherai GS, Shevell DE, Du S, Charles ED, Abdelmalek MF. PMID: 37088457.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    30. Meta-analysis: Prevalence of significant or advanced fibrosis in adults with alpha-1-antitrypsin deficiency. Aliment Pharmacol Ther. 2023 07; 58(2):152-158. Huang DQ, Chan KE, Tan C, Zeng RW, Koh B, Ong EYH, Ong CCH, Ong CEY, Tan DJH, Lim WH, Cho E, Tan EXX, Teng MLP, Ng CH, Nah B, Lim MC, Muthiah M, Clark VC, Loomba R. PMID: 37089038; PMCID: PMC10330074.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    31. Non-invasive diagnosis and monitoring of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis. Lancet Gastroenterol Hepatol. 2023 Jul; 8(7):660-670. Tincopa MA, Loomba R. PMID: 37060912.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    32. Global and national prevalence of nonalcoholic fatty liver disease in adolescents: An analysis of the global burden of disease study 2019. Hepatology. 2023 10 01; 78(4):1168-1181. Hartmann P, Zhang X, Loomba R, Schnabl B. PMID: 37021791; PMCID: PMC10521800.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    33. Global epidemiology of cirrhosis - aetiology, trends and predictions. Nat Rev Gastroenterol Hepatol. 2023 06; 20(6):388-398. Huang DQ, Terrault NA, Tacke F, Gluud LL, Arrese M, Bugianesi E, Loomba R. PMID: 36977794; PMCID: PMC10043867.
      View in: PubMed   Mentions: 47     Fields:    Translation:Humans
    34. Semaglutide 2·4 mg once weekly in patients with non-alcoholic steatohepatitis-related cirrhosis: a randomised, placebo-controlled phase 2 trial. Lancet Gastroenterol Hepatol. 2023 06; 8(6):511-522. Loomba R, Abdelmalek MF, Armstrong MJ, Jara M, Kjær MS, Krarup N, Lawitz E, Ratziu V, Sanyal AJ, Schattenberg JM, Newsome PN, NN9931-4492 investigators. PMID: 36934740; PMCID: PMC10792518.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCTClinical Trials
    35. Reply to: "Screening for NAFLD and its severity in type 2 diabetic patients: Value of magnetic resonance imaging and outstanding issues". J Hepatol. 2023 05; 78(5):e168-e169. Ajmera V, Loomba R. PMID: 36736737; PMCID: PMC10121872.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    36. Psoriatic disease and non-alcoholic fatty liver disease shared pathogenesis review. Semin Arthritis Rheum. 2023 04; 59:152165. Torosian K, Lal E, Kavanaugh A, Loomba R, Ajmera V, Guma M. PMID: 36716599; PMCID: PMC9992353.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    37. Safety, pharmacokinetics, and pharmacodynamics of pegozafermin in patients with non-alcoholic steatohepatitis: a randomised, double-blind, placebo-controlled, phase 1b/2a multiple-ascending-dose study. Lancet Gastroenterol Hepatol. 2023 02; 8(2):120-132. Loomba R, Lawitz EJ, Frias JP, Ortiz-Lasanta G, Johansson L, Franey BB, Morrow L, Rosenstock M, Hartsfield CL, Chen CY, Tseng L, Charlton RW, Mansbach H, Margalit M. PMID: 36521501.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCTClinical Trials
    38. A prospective study on the prevalence of NAFLD, advanced fibrosis, cirrhosis and hepatocellular carcinoma in people with type 2 diabetes. J Hepatol. 2023 03; 78(3):471-478. Ajmera V, Cepin S, Tesfai K, Hofflich H, Cadman K, Lopez S, Madamba E, Bettencourt R, Richards L, Behling C, Sirlin CB, Loomba R. PMID: 36410554; PMCID: PMC9975077.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    39. Review article: the role of HSD17B13 on global epidemiology, natural history, pathogenesis and treatment of NAFLD. Aliment Pharmacol Ther. 2023 01; 57(1):37-51. Amangurbanova M, Huang DQ, Loomba R. PMID: 36349732; PMCID: PMC10047549.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    40. Risk of advanced fibrosis in first-degree relatives of patients with nonalcoholic fatty liver disease. J Clin Invest. 2022 11 01; 132(21). Tamaki N, Ahlholm N, Luukkonen PK, Porthan K, Sharpton SR, Ajmera V, Kono Y, Dave S, Ahmed A, Sundaram V, Wilkinson MJ, Patton H, Gupta H, Cervantes V, Hernandez C, Lopez SJ, Loomba R, Baumgartner A, Richards L, Arkkila PE, Nemes K, Isoniemi H, Yki-Järvinen H, Loomba R. PMID: 36317632; PMCID: PMC9621132.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    41. MRI Quantification of Placebo Effect in Nonalcoholic Steatohepatitis Clinical Trials. Radiology. 2023 03; 306(3):e220743. Nedrud MA, Chaudhry M, Middleton MS, Moylan CA, Lerebours R, Luo S, Farjat A, Guy C, Loomba R, Abdelmalek MF, Sirlin CB, Bashir MR. PMID: 36318027; PMCID: PMC9968769.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    42. Global epidemiology of alcohol-associated cirrhosis and HCC: trends, projections and risk factors. Nat Rev Gastroenterol Hepatol. 2023 01; 20(1):37-49. Huang DQ, Mathurin P, Cortez-Pinto H, Loomba R. PMID: 36258033; PMCID: PMC9579565.
      View in: PubMed   Mentions: 50     Fields:    Translation:Humans
    43. Gut metagenome-derived signature predicts hepatic decompensation and mortality in NAFLD-related cirrhosis. Aliment Pharmacol Ther. 2022 11; 56(10):1475-1485. Sharpton SR, Oh TG, Madamba E, Wang C, Yu RT, Atkins AR, Huan T, Downes M, Evans RM, Loomba R. PMID: 36164267; PMCID: PMC9746351.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    44. Liver stiffness thresholds to predict disease progression and clinical outcomes in bridging fibrosis and cirrhosis. Gut. 2023 03; 72(3):581-589. Loomba R, Huang DQ, Sanyal AJ, Anstee QM, Trauner M, Lawitz EJ, Ding D, Ma L, Jia C, Billin A, Huss RS, Chung C, Goodman Z, Wong VW, Okanoue T, Romero-Gómez M, Abdelmalek MF, Muir A, Afdhal N, Bosch J, Harrison S, Younossi ZM, Myers RP. PMID: 36750244; PMCID: PMC9905707.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    45. Clinical Utility of Combined MRI-PDFF and ALT Response in Predicting Histologic Response in Nonalcoholic Fatty Liver Disease. Clin Gastroenterol Hepatol. 2023 09; 21(10):2682-2685.e4. Huang DQ, Sharpton SR, Amangurbanova M, Tamaki N, Sirlin CB, Loomba R, NAFLD RESEARCH STUDY GROUP. PMID: 36075503.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    46. Shared Mechanisms between Cardiovascular Disease and NAFLD. Semin Liver Dis. 2022 Nov; 42(4):455-464. Huang DQ, Downes M, Evans RM, Witztum JL, Glass CK, Loomba R. PMID: 36008083.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    47. Metabolic Injury of Hepatocytes Promotes Progression of NAFLD and AALD. Semin Liver Dis. 2022 08; 42(3):233-249. Carvalho-Gontijo R, Han C, Zhang L, Zhang V, Hosseini M, Mekeel K, Schnabl B, Loomba R, Karin M, Brenner DA, Kisseleva T. PMID: 36001995; PMCID: PMC9662188.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    48. Head-to-head comparison between MEFIB, MAST, and FAST for detecting stage 2 fibrosis or higher among patients with NAFLD. J Hepatol. 2022 12; 77(6):1482-1490. Kim BK, Tamaki N, Imajo K, Yoneda M, Sutter N, Jung J, Lin T, Tu XM, Bergstrom J, Nguyen K, Nguyen L, Le T, Madamba E, Richards L, Valasek MA, Behling C, Sirlin CB, Nakajima A, Loomba R. PMID: 35973577.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    49. Hepatocellular Carcinoma Incidence in Alcohol-Associated Cirrhosis: Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol. 2023 05; 21(5):1169-1177. Huang DQ, Tan DJH, Ng CH, Amangurbanova M, Sutter N, Lin Tay PW, Lim WH, Yong JN, Tang A, Syn N, Muthiah MD, Tan EXX, Dave S, Tay B, Majzoub AM, Gerberi D, Kim BK, Loomba R. PMID: 35940513; PMCID: PMC10792532.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    50. Liver Stiffness on Magnetic Resonance Elastography and the MEFIB Index and Liver-Related Outcomes in Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis of Individual Participants. Gastroenterology. 2022 10; 163(4):1079-1089.e5. Ajmera V, Kim BK, Yang K, Majzoub AM, Nayfeh T, Tamaki N, Izumi N, Nakajima A, Idilman R, Gumussoy M, Oz DK, Erden A, Quach NE, Tu X, Zhang X, Noureddin M, Allen AM, Loomba R. PMID: 35788349; PMCID: PMC9509452.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    51. Fazirsiran for Liver Disease Associated with Alpha1-Antitrypsin Deficiency. N Engl J Med. 2022 08 11; 387(6):514-524. Strnad P, Mandorfer M, Choudhury G, Griffiths W, Trautwein C, Loomba R, Schluep T, Chang T, Yi M, Given BD, Hamilton JC, San Martin J, Teckman JH. PMID: 35748699.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCellsCTClinical Trials
    52. Changing global epidemiology of liver cancer from 2010 to 2019: NASH is the fastest growing cause of liver cancer. Cell Metab. 2022 07 05; 34(7):969-977.e2. Huang DQ, Singal AG, Kono Y, Tan DJH, El-Serag HB, Loomba R. PMID: 35793659.
      View in: PubMed   Mentions: 79     Fields:    Translation:Humans
    53. Changes in the gut microbiome associated with liver stiffness improvement in nonalcoholic steatohepatitis. Therap Adv Gastroenterol. 2022; 15:17562848221098243. Sharpton SR, Podlaha O, Chuang JC, Gindin Y, Myers RP, Loomba R. PMID: 35601801; PMCID: PMC9121469.
      View in: PubMed   Mentions: 1  
    54. Editorial: screening for hepatocellular carcinoma in NAFLD cirrhosis-towards abbreviated MRI alternative in patients with obesity? Authors' reply. Aliment Pharmacol Ther. 2022 05; 55(9):1212-1213. Huang DQ, Loomba R. PMID: 35429041.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    55. Prognostic utility of magnetic resonance elastography and MEFIB index in predicting liver-related outcomes and mortality in individuals at risk of and with nonalcoholic fatty liver disease. Therap Adv Gastroenterol. 2022; 15:17562848221093869. Ajmera V, Nguyen K, Tamaki N, Sharpton S, Bettencourt R, Loomba R. PMID: 35509420; PMCID: PMC9058353.
      View in: PubMed   Mentions: 9  
    56. Noninvasive assessment of liver fibrosis and its clinical significance in nonalcoholic fatty liver disease. Hepatol Res. 2022 Jun; 52(6):497-507. Tamaki N, Kurosaki M, Huang DQ, Loomba R. PMID: 35352460; PMCID: PMC9718363.
      View in: PubMed   Mentions: 14  
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    58. Eliciting Patient Preferences for Hepatocellular Carcinoma Screening: A Choice-Based Conjoint Analysis. J Am Coll Radiol. 2022 04; 19(4):502-512. Fazeli S, Covarrubias Y, Bassirian S, Cuevas J, Fowler K, Vodkin I, Kono Y, Marks R, Loomba R, Taouli B, Sirlin C, Carlos R. PMID: 35248523.
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    59. Comparative efficacy of an optimal exam between ultrasound versus abbreviated MRI for HCC screening in NAFLD cirrhosis: A prospective study. Aliment Pharmacol Ther. 2022 04; 55(7):820-827. Huang DQ, Fowler KJ, Liau J, Cunha GM, Louie AL, An JY, Bettencourt R, Jung J, Gitto Z, Hernandez C, Lopez SJ, Gupta H, Sirlin CB, Marks RM, Loomba R. PMID: 35229334; PMCID: PMC9762322.
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    60. Two-Step Strategy, FIB-4 Followed by Magnetic Resonance Elastography, for Detecting Advanced Fibrosis in NAFLD. Clin Gastroenterol Hepatol. 2023 02; 21(2):380-387.e3. Tamaki N, Imajo K, Sharpton SR, Jung J, Sutter N, Kawamura N, Yoneda M, Valasek MA, Behling C, Sirlin CB, Kurosaki M, Izumi N, Nakajima A, Loomba R. PMID: 35123096.
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    61. Utilizing Macrosteatotic Allografts for Nonalcoholic Steatohepatitis Recipients. Liver Transpl. 2022 04; 28(4):552-553. Brubaker AL, Loomba R. PMID: 34806817; PMCID: PMC9683541.
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    62. Magnetic resonance elastography plus Fibrosis-4 versus FibroScan-aspartate aminotransferase in detection of candidates for pharmacological treatment of NASH-related fibrosis. Hepatology. 2022 03; 75(3):661-672. Tamaki N, Imajo K, Sharpton S, Jung J, Kawamura N, Yoneda M, Valasek MA, Behling C, Sirlin CB, Nakajima A, Loomba R. PMID: 34496054; PMCID: PMC9683538.
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    63. The role of Mesothelin signaling in Portal Fibroblasts in the pathogenesis of cholestatic liver fibrosis. Front Mol Biosci. 2021; 8:790032. Fuji H, Miller G, Nishio T, Koyama Y, Lam K, Zhang V, Loomba R, Brenner D, Kisseleva T. PMID: 34966784; PMCID: PMC8710774.
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    64. Noninvasive Risk Stratification for Nonalcoholic Fatty Liver Disease Among Living Liver Donor Candidates: A Proposed Algorithm. Liver Transpl. 2022 04; 28(4):670-677. Danis N, Weeks SR, Kim A, Baghdadi A, Ghadimi M, Kamel IR, Saberi B, Woreta T, Garonzik-Wang J, Philosophe B, Gurakar A, Loomba R. PMID: 34753223; PMCID: PMC9683539.
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    65. Comparative diagnostic performance of ultrasound shear wave elastography and magnetic resonance elastography for classifying fibrosis stage in adults with biopsy-proven nonalcoholic fatty liver disease. Eur Radiol. 2022 Apr; 32(4):2457-2469. Zhang YN, Fowler KJ, Boehringer AS, Montes V, Schlein AN, Covarrubias Y, Wolfson T, Hong CW, Valasek MA, Andre MP, Loomba R, Sirlin CB. PMID: 34854929; PMCID: PMC8921157.
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    66. Non-invasive methods for imaging hepatic steatosis and their clinical importance in NAFLD. Nat Rev Endocrinol. 2022 01; 18(1):55-66. Tamaki N, Ajmera V, Loomba R. PMID: 34815553; PMCID: PMC9012520.
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    67. Expert Panel Review to Compare FDA and EMA Guidance on Drug Development and Endpoints in Nonalcoholic Steatohepatitis. Gastroenterology. 2022 03; 162(3):680-688. Loomba R, Ratziu V, Harrison SA, NASH Clinical Trial Design International Working Group. PMID: 34822801; PMCID: PMC9683540.
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    68. A Randomized, Controlled Trial of the Pan-PPAR Agonist Lanifibranor in NASH. N Engl J Med. 2021 10 21; 385(17):1547-1558. Francque SM, Bedossa P, Ratziu V, Anstee QM, Bugianesi E, Sanyal AJ, Loomba R, Harrison SA, Balabanska R, Mateva L, Lanthier N, Alkhouri N, Moreno C, Schattenberg JM, Stefanova-Petrova D, Vonghia L, Rouzier R, Guillaume M, Hodge A, Romero-Gómez M, Huot-Marchand P, Baudin M, Richard MP, Abitbol JL, Broqua P, Junien JL, Abdelmalek MF, NATIVE Study Group. PMID: 34670042.
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    69. Prospective Study of Outcomes in Adults with Nonalcoholic Fatty Liver Disease. N Engl J Med. 2021 10 21; 385(17):1559-1569. Sanyal AJ, Van Natta ML, Clark J, Neuschwander-Tetri BA, Diehl A, Dasarathy S, Loomba R, Chalasani N, Kowdley K, Hameed B, Wilson LA, Yates KP, Belt P, Lazo M, Kleiner DE, Behling C, Tonascia J, NASH Clinical Research Network (CRN). PMID: 34670043; PMCID: PMC8881985.
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    70. Diagnostic accuracy of two-dimensional shear wave elastography and transient elastography in nonalcoholic fatty liver disease. Therap Adv Gastroenterol. 2021; 14:17562848211050436. Sharpton SR, Tamaki N, Bettencourt R, Madamba E, Jung J, Liu A, Behling C, Valasek MA, Loomba R. PMID: 34646360; PMCID: PMC8504217.
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    71. TVB-2640 (FASN Inhibitor) for the Treatment of Nonalcoholic Steatohepatitis: FASCINATE-1, a Randomized, Placebo-Controlled Phase 2a Trial. Gastroenterology. 2021 11; 161(5):1475-1486. Loomba R, Mohseni R, Lucas KJ, Gutierrez JA, Perry RG, Trotter JF, Rahimi RS, Harrison SA, Ajmera V, Wayne JD, O'Farrell M, McCulloch W, Grimmer K, Rinella M, Wai-Sun Wong V, Ratziu V, Gores GJ, Neuschwander-Tetri BA, Kemble G. PMID: 34310978.
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    72. Risk Difference of Liver-Related and Cardiovascular Events by Liver Fibrosis Status in Nonalcoholic Fatty Liver Disease. Clin Gastroenterol Hepatol. 2022 05; 20(5):1171-1173.e2. Tamaki N, Higuchi M, Kurosaki M, Loomba R, Izumi N, MRCH Liver Study Group. PMID: 34280550; PMCID: PMC8761224.
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    73. Letter: coronary atherosclerosis in patients with significant hepatic fibrosis in non-alcoholic fatty liver disease-a realm for non-invasive testing. Authors' reply. Aliment Pharmacol Ther. 2021 07; 54(2):216. Park JG, Jung J, Loomba R. PMID: 34170539.
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    74. Optimal Threshold of Controlled Attenuation Parameter for Detection of HIV-Associated NAFLD With Magnetic Resonance Imaging as the Reference Standard. Clin Infect Dis. 2021 06 15; 72(12):2124-2131. Ajmera VH, Cachay ER, Ramers CB, Bassirian S, Singh S, Bettencourt R, Richards L, Hamilton G, Middleton M, Fowler K, Sirlin C, Loomba R. PMID: 32975278; PMCID: PMC8204791.
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    75. Cost-Related Nonadherence to Medications Among US Adults With Chronic Liver Diseases. Mayo Clin Proc. 2021 10; 96(10):2639-2650. Lago-Hernandez C, Nguyen NH, Khera R, Loomba R, Asrani SK, Singh S. PMID: 34120754; PMCID: PMC8492496.
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    76. Financial Hardship From Medical Bills Among Adults With Chronic Liver Diseases: National Estimates From the United States. Hepatology. 2021 09; 74(3):1509-1522. Lago-Hernandez C, Nguyen NH, Khera R, Loomba R, Asrani SK, Singh S. PMID: 33772833.
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    77. Editorial: liver stiffness by magnetic resonance elastography and cardiovascular risk in non-alcoholic fatty liver disease-simply associated or more complicated? Authors' reply. Aliment Pharmacol Ther. 2021 06; 53(11):1230-1231. Park JG, Jung J, Loomba R. PMID: 33961702.
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    78. Mechanisms and disease consequences of nonalcoholic fatty liver disease. Cell. 2021 05 13; 184(10):2537-2564. Loomba R, Friedman SL, Shulman GI. PMID: 33989548.
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    79. The impact of genetic risk on liver fibrosis in non-alcoholic fatty liver disease as assessed by magnetic resonance elastography. Aliment Pharmacol Ther. 2021 07; 54(1):68-77. Ajmera V, Liu A, Bettencourt R, Dhar D, Richards L, Loomba R. PMID: 33975381; PMCID: PMC8985656.
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    80. Clinical utility of 30% relative decline in MRI-PDFF in predicting fibrosis regression in non-alcoholic fatty liver disease. Gut. 2022 05; 71(5):983-990. Tamaki N, Munaganuru N, Jung J, Yonan AQ, Loomba RR, Bettencourt R, Ajmera V, Valasek MA, Behling C, Sirlin CB, Loomba R. PMID: 33883248; PMCID: PMC8594562.
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    81. Emerging Metabolic and Transcriptomic Signature of PNPLA3-Associated NASH. Hepatology. 2021 04; 73(4):1248-1250. Dhar D, Loomba R. PMID: 33544416; PMCID: PMC9683537.
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    82. Liver stiffness by magnetic resonance elastography is associated with increased risk of cardiovascular disease in patients with non-alcoholic fatty liver disease. Aliment Pharmacol Ther. 2021 05; 53(9):1030-1037. Park JG, Jung J, Verma KK, Kang MK, Madamba E, Lopez S, Qas Yonan A, Liu A, Bettencourt R, Sirlin C, Loomba R. PMID: 33764550; PMCID: PMC8514119.
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    83. MRI-Proton Density Fat Fraction Treatment Response Criteria in Nonalcoholic Steatohepatitis. Hepatology. 2021 03; 73(3):881-883. Loomba R. PMID: 33179266; PMCID: PMC8221026.
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    84. RAMIC: Design of a randomized, double-blind, placebo-controlled trial to evaluate the efficacy of ramipril in patients with COVID-19. Contemp Clin Trials. 2021 04; 103:106330. Ajmera V, Thompson WK, Smith DM, Malhotra A, Mehta RL, Tolia V, Yin J, Sriram K, Insel PA, Collier S, Richards L, Loomba R. PMID: 33631357; PMCID: PMC7899027.
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    85. Repeatability and accuracy of various region-of-interest sampling strategies for hepatic MRI proton density fat fraction quantification. Abdom Radiol (NY). 2021 07; 46(7):3105-3116. Hong CW, Cui JY, Batakis D, Xu Y, Wolfson T, Gamst AC, Schlein AN, Negrete LM, Middleton MS, Hamilton G, Loomba R, Schwimmer JB, Fowler KJ, Sirlin CB. PMID: 33609166; PMCID: PMC8983333.
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    86. Complementary role of EUS, EndoFLIP, and manometry for management of type III achalasia with peroral endoscopic myotomy in a patient with compensated cirrhosis and no varices. VideoGIE. 2021 Apr; 6(4):167-169. Fejleh MP, Yadlapati R, Mendler MH, Loomba R, Kwong WT, Abbas Fehmi SM. PMID: 33898892; PMCID: PMC8058387.
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    87. Combination Therapies Including Cilofexor and Firsocostat for Bridging Fibrosis and Cirrhosis Attributable to NASH. Hepatology. 2021 02; 73(2):625-643. Loomba R, Noureddin M, Kowdley KV, Kohli A, Sheikh A, Neff G, Bhandari BR, Gunn N, Caldwell SH, Goodman Z, Wapinski I, Resnick M, Beck AH, Ding D, Jia C, Chuang JC, Huss RS, Chung C, Subramanian GM, Myers RP, Patel K, Borg BB, Ghalib R, Kabler H, Poulos J, Younes Z, Elkhashab M, Hassanein T, Iyer R, Ruane P, Shiffman ML, Strasser S, Wong VW, Alkhouri N, for the ATLAS Investigators. PMID: 33169409.
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    89. The Commensal Microbe Veillonella as a Marker for Response to an FGF19 Analog in NASH. Hepatology. 2021 01; 73(1):126-143. Loomba R, Ling L, Dinh DM, DePaoli AM, Lieu HD, Harrison SA, Sanyal AJ. PMID: 32794259; PMCID: PMC7898628.
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    90. Current Concepts, Opportunities, and Challenges of Gut Microbiome-Based Personalized Medicine in Nonalcoholic Fatty Liver Disease. Cell Metab. 2021 01 05; 33(1):21-32. Sharpton SR, Schnabl B, Knight R, Loomba R. PMID: 33296678; PMCID: PMC8414992.
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    92. Targeting the renin-angiotensin signaling pathway in COVID-19: Unanswered questions, opportunities, and challenges. Proc Natl Acad Sci U S A. 2020 11 24; 117(47):29274-29282. Sriram K, Loomba R, Insel PA. PMID: 33203679; PMCID: PMC7703541.
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    93. Comparative Effectiveness of Entecavir Versus Tenofovir for Preventing Hepatocellular Carcinoma in Patients with Chronic Hepatitis B: A Systematic Review and Meta-Analysis. Hepatology. 2021 01; 73(1):68-78. Dave S, Park S, Murad MH, Barnard A, Prokop L, Adams LA, Singh S, Loomba R. PMID: 32277491; PMCID: PMC8022893.
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    94. Clinical Utility of Change in Nonalcoholic Fatty Liver Disease Activity Score and Change in Fibrosis in NAFLD. Clin Gastroenterol Hepatol. 2021 12; 19(12):2673-2674.e3. Tamaki N, Munaganuru N, Jung J, Yonan AQ, Bettencourt R, Ajmera V, Valasek MA, Behling C, Loomba R. PMID: 33157318; PMCID: PMC8438785.
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    95. RAAS Inhibitors and Risk of Covid-19. N Engl J Med. 2020 Nov 12; 383(20):1991-1992. Sriram K, Loomba R, Insel PA. PMID: 33108103.
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    96. Multicenter Validation of Association Between Decline in MRI-PDFF and Histologic Response in NASH. Hepatology. 2020 10; 72(4):1219-1229. Loomba R, Neuschwander-Tetri BA, Sanyal A, Chalasani N, Diehl AM, Terrault N, Kowdley K, Dasarathy S, Kleiner D, Behling C, Lavine J, Van Natta M, Middleton M, Tonascia J, Sirlin C, NASH Clinical Research Network. PMID: 31965579; PMCID: PMC8055244.
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    98. Functional Microbiomics Reveals Alterations of the Gut Microbiome and Host Co-Metabolism in Patients With Alcoholic Hepatitis. Hepatol Commun. 2020 Aug; 4(8):1168-1182. Gao B, Duan Y, Lang S, Barupal D, Wu TC, Valdiviez L, Roberts B, Choy YY, Shen T, Byram G, Zhang Y, Fan S, Wancewicz B, Shao Y, Vervier K, Wang Y, Zhou R, Jiang L, Nath S, Loomba R, Abraldes JG, Bataller R, Tu XM, Stärkel P, Lawley TD, Fiehn O, Schnabl B. PMID: 32766476; PMCID: PMC7395072.
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    107. AGA Clinical Practice Update on Screening and Surveillance for Hepatocellular Carcinoma in Patients With Nonalcoholic Fatty Liver Disease: Expert Review. Gastroenterology. 2020 05; 158(6):1822-1830. Loomba R, Lim JK, Patton H, El-Serag HB. PMID: 32006545; PMCID: PMC8012107.
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    114. Discovery of Half-life of Circulating Hepatitis B Surface Antigen in Patients With Chronic Hepatitis B Infection Using Heavy Water Labeling. Clin Infect Dis. 2019 07 18; 69(3):542-545. Loomba R, Decaris M, Li KW, Shankaran M, Mohammed H, Matthews M, Richards LM, Nguyen P, Rizo E, Andrews B, Soto R, Angel T, Suri V, Kitrinos KM, Barnes D, Czerwieniec G, Brendza K, Subramanian GM, Gaggar A, Hellerstein MK. PMID: 30590481.
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    120. Glyphosate Excretion is Associated With Steatohepatitis and Advanced Liver Fibrosis in Patients With Fatty Liver Disease. Clin Gastroenterol Hepatol. 2020 03; 18(3):741-743. Mills PJ, Caussy C, Loomba R. PMID: 30954713; PMCID: PMC6776714.
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    121. A gut microbiome signature for cirrhosis due to nonalcoholic fatty liver disease. Nat Commun. 2019 03 29; 10(1):1406. Caussy C, Tripathi A, Humphrey G, Bassirian S, Singh S, Faulkner C, Bettencourt R, Rizo E, Richards L, Xu ZZ, Downes MR, Evans RM, Brenner DA, Sirlin CB, Knight R, Loomba R. PMID: 30926798; PMCID: PMC6440960.
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    125. Inter-reader agreement of magnetic resonance imaging proton density fat fraction and its longitudinal change in a clinical trial of adults with nonalcoholic steatohepatitis. Abdom Radiol (NY). 2019 02; 44(2):482-492. Hooker JC, Hamilton G, Park CC, Liao S, Wolfson T, Dehkordy SF, Hong CW, Mamidipalli A, Gamst A, Loomba R, Sirlin CB. PMID: 30128694; PMCID: PMC6382605.
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    126. Reader agreement and accuracy of ultrasound features for hepatic steatosis. Abdom Radiol (NY). 2019 01; 44(1):54-64. Hong CW, Marsh A, Wolfson T, Paige J, Dekhordy SF, Schlein AN, Housman E, Deiranieh LH, Li CQ, Wasnik AP, Jang HJ, Dietrich CF, Piscaglia F, Casola G, O'Boyle M, Richman KM, Valasek MA, Andre M, Loomba R, Sirlin CB. PMID: 29951900; PMCID: PMC6310678.
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    130. Enzyme promiscuity drives branched-chain fatty acid synthesis in adipose tissues. Nat Chem Biol. 2018 11; 14(11):1021-1031. Wallace M, Green CR, Roberts LS, Lee YM, McCarville JL, Sanchez-Gurmaches J, Meurs N, Gengatharan JM, Hover JD, Phillips SA, Ciaraldi TP, Guertin DA, Cabrales P, Ayres JS, Nomura DK, Loomba R, Metallo CM. PMID: 30327559; PMCID: PMC6245668.
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    135. ER Stress Drives Lipogenesis and Steatohepatitis via Caspase-2 Activation of S1P. Cell. 2018 09 20; 175(1):133-145.e15. Kim JY, Garcia-Carbonell R, Yamachika S, Zhao P, Dhar D, Loomba R, Kaufman RJ, Saltiel AR, Karin M. PMID: 30220454; PMCID: PMC6159928.
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    138. Refining Sample-Size Estimations Based Upon Placebo Response in Trials of Agents for Nonalcoholic Fatty Liver Disease. Clin Gastroenterol Hepatol. 2019 03; 17(4):607-609. Ajmera V, Loomba R. PMID: 30153521.
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    139. Noninvasive, Quantitative Assessment of Liver Fat by MRI-PDFF as an Endpoint in NASH Trials. Hepatology. 2018 08; 68(2):763-772. Caussy C, Reeder SB, Sirlin CB, Loomba R. PMID: 29356032; PMCID: PMC6054824.
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    140. GS-0976 Reduces Hepatic Steatosis and Fibrosis Markers in Patients With Nonalcoholic Fatty Liver Disease. Gastroenterology. 2018 11; 155(5):1463-1473.e6. Loomba R, Kayali Z, Noureddin M, Ruane P, Lawitz EJ, Bennett M, Wang L, Harting E, Tarrant JM, McColgan BJ, Chung C, Ray AS, Subramanian GM, Myers RP, Middleton MS, Lai M, Charlton M, Harrison SA. PMID: 30059671; PMCID: PMC6318218.
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    144. Modulation of the intestinal bile acid/farnesoid X receptor/fibroblast growth factor 15 axis improves alcoholic liver disease in mice. Hepatology. 2018 06; 67(6):2150-2166. Hartmann P, Hochrath K, Horvath A, Chen P, Seebauer CT, Llorente C, Wang L, Alnouti Y, Fouts DE, Stärkel P, Loomba R, Coulter S, Liddle C, Yu RT, Ling L, Rossi SJ, DePaoli AM, Downes M, Evans RM, Brenner DA, Schnabl B. PMID: 29159825; PMCID: PMC5962369.
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    146. Dysregulation of serum bile acids and FGF19 in alcoholic hepatitis. J Hepatol. 2018 08; 69(2):396-405. Brandl K, Hartmann P, Jih LJ, Pizzo DP, Argemi J, Ventura-Cots M, Coulter S, Liddle C, Ling L, Rossi SJ, DePaoli AM, Loomba R, Mehal WZ, Fouts DE, Lucey MR, Bosques-Padilla F, Mathurin P, Louvet A, Garcia-Tsao G, Verna EC, Abraldes JG, Brown RS, Vargas V, Altamirano J, Caballería J, Shawcross D, Stärkel P, Ho SB, Bataller R, Schnabl B. PMID: 29654817; PMCID: PMC6054564.
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    148. Can Elastography Differentiate Isolated Fatty Liver from Nonalcoholic Steatohepatitis? Semin Liver Dis. 2018 02; 38(1):14-20. Ajmera V, Loomba R. PMID: 29471562.
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    150. DNA methylation signatures reflect aging in patients with nonalcoholic steatohepatitis. JCI Insight. 2018 01 25; 3(2). Loomba R, Gindin Y, Jiang Z, Lawitz E, Caldwell S, Djedjos CS, Xu R, Chung C, Myers RP, Subramanian GM, Goodman Z, Charlton M, Afdhal NH, Diehl AM. PMID: 29367468; PMCID: PMC5821203.
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    151. Association Between Obesity and Discordance in Fibrosis Stage Determination by Magnetic Resonance vs Transient Elastography in Patients With Nonalcoholic Liver Disease. Clin Gastroenterol Hepatol. 2018 12; 16(12):1974-1982.e7. Caussy C, Chen J, Alquiraish MH, Cepin S, Nguyen P, Hernandez C, Yin M, Bettencourt R, Cachay ER, Jayakumar S, Fortney L, Hooker J, Sy E, Valasek MA, Rizo E, Richards L, Brenner DA, Sirlin CB, Ehman RL, Loomba R. PMID: 29104128; PMCID: PMC6050151.
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    155. Do Zones of Hepatic Steatosis Associate With Subtypes and Progression of Nonalcoholic Fatty Liver Disease in Children? Clin Gastroenterol Hepatol. 2018 03; 16(3):341-342. Ajmera V, Loomba R. PMID: 29199148; PMCID: PMC5881903.
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    157. Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity. Nature. 2017 11 16; 551(7680):340-345. Shalapour S, Lin XJ, Bastian IN, Brain J, Burt AD, Aksenov AA, Vrbanac AF, Li W, Perkins A, Matsutani T, Zhong Z, Dhar D, Navas-Molina JA, Xu J, Loomba R, Downes M, Yu RT, Evans RM, Dorrestein PC, Knight R, Benner C, Anstee QM, Karin M. PMID: 29144460; PMCID: PMC5884449.
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    168. Magnitude and Kinetics of Decrease in Liver Stiffness After Antiviral Therapy in Patients With Chronic Hepatitis C: A Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol. 2018 Jan; 16(1):27-38.e4. Singh S, Facciorusso A, Loomba R, Falck-Ytter YT. PMID: 28479504; PMCID: PMC5671365.
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    237. Commentary: non-alcoholic fatty pancreas -- toward an uncharted territory; authors' reply. Aliment Pharmacol Ther. 2013 May; 37(9):916-7. Patel NS, Loomba R. PMID: 23551158; PMCID: PMC4135375.
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    238. Effect of flip angle on the accuracy and repeatability of hepatic proton density fat fraction estimation by complex data-based, T1-independent, T2*-corrected, spectrum-modeled MRI. J Magn Reson Imaging. 2014 Feb; 39(2):440-7. Johnson BL, Schroeder ME, Wolfson T, Gamst AC, Hamilton G, Shiehmorteza M, Loomba R, Schwimmer JB, Reeder S, Middleton MS, Sirlin CB. PMID: 23596052; PMCID: PMC3732566.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    239. Serum γ-glutamyltranspeptidase predicts all-cause, cardiovascular and liver mortality in older adults. J Clin Exp Hepatol. 2013 Mar 01; 3(1):4-11. Loomba R, Doycheva I, Bettencourt R, Cohen B, Wassel CL, Brenner D, Barrett-Connor E. PMID: 23997501; PMCID: PMC3940213.
      View in: PubMed   Mentions: 18  
    240. Association between novel MRI-estimated pancreatic fat and liver histology-determined steatosis and fibrosis in non-alcoholic fatty liver disease. Aliment Pharmacol Ther. 2013 Mar; 37(6):630-9. Patel NS, Peterson MR, Brenner DA, Heba E, Sirlin C, Loomba R. PMID: 23383649; PMCID: PMC4136524.
      View in: PubMed   Mentions: 59     Fields:    Translation:Humans
    241. Transforming growth factor-β signaling in hepatocytes promotes hepatic fibrosis and carcinogenesis in mice with hepatocyte-specific deletion of TAK1. Gastroenterology. 2013 May; 144(5):1042-1054.e4. Yang L, Inokuchi S, Roh YS, Song J, Loomba R, Park EJ, Seki E. PMID: 23391818; PMCID: PMC3752402.
      View in: PubMed   Mentions: 74     Fields:    Translation:AnimalsCells
    242. Nonalcoholic fatty liver disease: MR imaging of liver proton density fat fraction to assess hepatic steatosis. Radiology. 2013 May; 267(2):422-31. Tang A, Tan J, Sun M, Hamilton G, Bydder M, Wolfson T, Gamst AC, Middleton M, Brunt EM, Loomba R, Lavine JE, Schwimmer JB, Sirlin CB. PMID: 23382291; PMCID: PMC3632805.
      View in: PubMed   Mentions: 223     Fields:    Translation:Humans
    243. Synergism between obesity and alcohol in increasing the risk of hepatocellular carcinoma: a prospective cohort study. Am J Epidemiol. 2013 02 15; 177(4):333-42. Loomba R, Yang HI, Su J, Brenner D, Barrett-Connor E, Iloeje U, Chen CJ. PMID: 23355498; PMCID: PMC3626057.
      View in: PubMed   Mentions: 75     Fields:    Translation:Humans
    244. Prognostic implication of liver histology in patients with nonalcoholic fatty liver disease in diabetes. J Diabetes Complications. 2013 May-Jun; 27(3):293-300. Doycheva I, Patel N, Peterson M, Loomba R. PMID: 23312215; PMCID: PMC4167586.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    245. Review article: the emerging interplay among the gastrointestinal tract, bile acids and incretins in the pathogenesis of diabetes and non-alcoholic fatty liver disease. Aliment Pharmacol Ther. 2012 Nov; 36(10):909-21. Zarrinpar A, Loomba R. PMID: 23057494; PMCID: PMC3535499.
      View in: PubMed   Mentions: 51     Fields:    Translation:Humans
    246. Nonalcoholic fatty liver disease: Indications for liver biopsy and noninvasive biomarkers. Clin Liver Dis (Hoboken). 2012 Sep; 1(4):104-107. Noureddin M, Loomba R. PMID: 31186861; PMCID: PMC6499277.
      View in: PubMed   Mentions: 21  
    247. Association between diabetes, family history of diabetes, and risk of nonalcoholic steatohepatitis and fibrosis. Hepatology. 2012 Sep; 56(3):943-51. Loomba R, Abraham M, Unalp A, Wilson L, Lavine J, Doo E, Bass NM, Nonalcoholic Steatohepatitis Clinical Research Network. PMID: 22505194; PMCID: PMC3407289.
      View in: PubMed   Mentions: 212     Fields:    Translation:Humans
    248. Management of Non-alcoholic Fatty Liver Disease and Steatohepatitis. J Clin Exp Hepatol. 2012 Jun; 2(2):156-73. Le TA, Loomba R. PMID: 25755424; PMCID: PMC3940181.
      View in: PubMed   Mentions: 16  
    249. Effect of colesevelam on liver fat quantified by magnetic resonance in nonalcoholic steatohepatitis: a randomized controlled trial. Hepatology. 2012 Sep; 56(3):922-32. Le TA, Chen J, Changchien C, Peterson MR, Kono Y, Patton H, Cohen BL, Brenner D, Sirlin C, Loomba R, San Diego Integrated NAFLD Research Consortium (SINC). PMID: 22431131; PMCID: PMC3400720.
      View in: PubMed   Mentions: 137     Fields:    Translation:Humans
    250. Correlation between liver histology and novel magnetic resonance imaging in adult patients with non-alcoholic fatty liver disease - MRI accurately quantifies hepatic steatosis in NAFLD. Aliment Pharmacol Ther. 2012 Jul; 36(1):22-9. Permutt Z, Le TA, Peterson MR, Seki E, Brenner DA, Sirlin C, Loomba R. PMID: 22554256; PMCID: PMC3437221.
      View in: PubMed   Mentions: 160     Fields:    Translation:Humans
    251. Association between serum interleukin-6 concentrations and mortality in older adults: the Rancho Bernardo study. PLoS One. 2012; 7(4):e34218. Lee JK, Bettencourt R, Brenner D, Le TA, Barrett-Connor E, Loomba R. PMID: 22514624; PMCID: PMC3325993.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    252. Meta-analysis: pioglitazone improves liver histology and fibrosis in patients with non-alcoholic steatohepatitis. Aliment Pharmacol Ther. 2012 Jan; 35(1):66-75. Boettcher E, Csako G, Pucino F, Wesley R, Loomba R. PMID: 22050199; PMCID: PMC3488596.
      View in: PubMed   Mentions: 122     Fields:    Translation:Humans
    253. Serum levels of alanine aminotransferase decrease with age in longitudinal analysis. Clin Gastroenterol Hepatol. 2012 Mar; 10(3):285-90.e1. Dong MH, Bettencourt R, Brenner DA, Barrett-Connor E, Loomba R. PMID: 22020064; PMCID: PMC3288181.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    254. Family history of peripheral artery disease is associated with prevalence and severity of peripheral artery disease: the San Diego population study. J Am Coll Cardiol. 2011 Sep 20; 58(13):1386-92. Wassel CL, Loomba R, Ix JH, Allison MA, Denenberg JO, Criqui MH. PMID: 21920269; PMCID: PMC3215334.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    255. Alanine aminotransferase decreases with age: the Rancho Bernardo Study. PLoS One. 2010 Dec 08; 5(12):e14254. Dong MH, Bettencourt R, Barrett-Connor E, Loomba R. PMID: 21170382; PMCID: PMC2999530.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    256. Obesity and alcohol synergize to increase the risk of incident hepatocellular carcinoma in men. Clin Gastroenterol Hepatol. 2010 Oct; 8(10):891-8, 898.e1-2. Loomba R, Yang HI, Su J, Brenner D, Iloeje U, Chen CJ. PMID: 20621202.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    257. Genetic covariance between gamma-glutamyl transpeptidase and fatty liver risk factors: role of beta2-adrenergic receptor genetic variation in twins. Gastroenterology. 2010 Sep; 139(3):836-45, 845.e1. Loomba R, Rao F, Zhang L, Khandrika S, Ziegler MG, Brenner DA, O'Connor DT. PMID: 20537997; PMCID: PMC3038676.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    258. Advances in pediatric nonalcoholic fatty liver disease. Hepatology. 2009 Oct; 50(4):1282-93. Loomba R, Sirlin CB, Schwimmer JB, Lavine JE. PMID: 19637286; PMCID: PMC2757471.
      View in: PubMed   Mentions: 98     Fields:    Translation:Humans
    259. Synergistic association between alcohol intake and body mass index with serum alanine and aspartate aminotransferase levels in older adults: the Rancho Bernardo Study. Aliment Pharmacol Ther. 2009 Dec 01; 30(11-12):1137-49. Loomba R, Bettencourt R, Barrett-Connor E. PMID: 19737152; PMCID: PMC3220929.
      View in: PubMed   Mentions: 53     Fields:    Translation:Humans
    260. Drug targets in hepatitis B virus infection. Infect Disord Drug Targets. 2009 Apr; 9(2):105-16. Stein LL, Loomba R. PMID: 19275699; PMCID: PMC6658185.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCellsPHPublic Health
    261. Role of fluoroquinolones in the primary prophylaxis of spontaneous bacterial peritonitis: meta-analysis. Clin Gastroenterol Hepatol. 2009 Apr; 7(4):487-493. Loomba R, Wesley R, Bain A, Csako G, Pucino F. PMID: 19250986; PMCID: PMC5807076.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    262. Placebo in nonalcoholic steatohepatitis: insight into natural history and implications for future clinical trials. Clin Gastroenterol Hepatol. 2008 Nov; 6(11):1243-8. Loomba R, Wesley R, Pucino F, Liang TJ, Kleiner DE, Lavine JE. PMID: 18829391; PMCID: PMC3133944.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    263. Hepatitis B immunoglobulin and Lamivudine improve hepatitis B-related outcomes after liver transplantation: meta-analysis. Clin Gastroenterol Hepatol. 2008 Jun; 6(6):696-700. Loomba R, Rowley AK, Wesley R, Smith KG, Liang TJ, Pucino F, Csako G. PMID: 18456569; PMCID: PMC2729093.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    264. Systematic review: the effect of preventive lamivudine on hepatitis B reactivation during chemotherapy. Ann Intern Med. 2008 Apr 01; 148(7):519-28. Loomba R, Rowley A, Wesley R, Liang TJ, Hoofnagle JH, Pucino F, Csako G. PMID: 18378948; PMCID: PMC2729097.
      View in: PubMed   Mentions: 179     Fields:    Translation:Humans
    265. Treatment of chronic hepatitis B. Antivir Ther. 2007; 12 Suppl 3:H33-41. Loomba R, Liang TJ. PMID: 18284181.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
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