Jack Dixon

Title(s)Emeritus Professor, Pharmacology
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    Lafora epilepsy mechanisms: insights into brain metabolism
    NIH R13NS096928May 1, 2016 - Apr 30, 2017
    Role: Principal Investigator
    YopT: A Yersinia Virulence Factor
    NIH R21AI064614Apr 15, 2005 - Mar 31, 2007
    Role: Principal Investigator
    Fic-mediated Adenylylation
    NIH R01GM090328May 15, 2004 - Jul 31, 2015
    Role: Principal Investigator
    Molecular Mechanism of Pathogenesis
    NIH R01AI060662May 15, 2004 - Apr 30, 2010
    Role: Principal Investigator
    Conference: Second Messengers &Protein Phosphorylation
    NIH R13DK060093Jun 1, 2001 - May 31, 2002
    Role: Principal Investigator
    FASEB SUMMER CONFERENCE--RECEPTORS/SIGNAL TRANSDUCTION
    NIH R13DK058154Jul 17, 2000 - Jun 30, 2001
    Role: Principal Investigator
    Protein phosphorylation and growth factor function
    NIH R01GM051586Aug 1, 1994 - Jun 30, 2025
    Role: Principal Investigator
    MODEL 370A-01 AUTOMATED DNA SEQUENCER SYSTEM
    NIH S10RR004849Jul 20, 1989 - Jan 19, 1991
    Role: Principal Investigator
    IVEM and Image Analysis Resource
    NIH P41RR004050Dec 12, 1988 - Mar 31, 2014
    Role: Co-Investigator
    EUCARYOTIC METABOLIC REGULATION
    NIH T32DK007532Dec 1, 1986 - Nov 30, 1997
    Role: Principal Investigator
    National Biomedical NMR Resource at Madison
    NIH P41RR002301Jul 1, 1985 - Feb 28, 2015
    Role: Co-Investigator
    Gastointestinal Hormone Research Core Center
    NIH P30DK034933Sep 30, 1984 - Nov 30, 2016
    Role: Co-Investigator
    ENDOCRINOLOGY STUDY SECTION
    NIH U09RG011666Jul 1, 1984 - Jun 30, 1991
    Role: Principal Investigator
    Novel Secreted Kinases
    NIH R01DK018024Jun 1, 1979 - Jul 31, 2020
    Role: Principal Investigator
    Phosphoinositide Phosphatases
    NIH R37DK018024Jun 1, 1979 - Jul 31, 2014
    Role: Principal Investigator
    STUDIES ON PANCREATIC HORMONES
    NIH R01AM018024Jun 1, 1979 - May 31, 1988
    Role: Principal Investigator
    General Clinical Research Center
    NIH M01RR000042Dec 1, 1977 - Feb 28, 2011
    Role: Co-Investigator
    Michigan Diabetes Research and Training Center
    NIH P60DK020572Sep 1, 1977 - Feb 9, 2013
    Role: Co-Investigator
    Regulation and Function of the Secretory Phosphoproteome
    NIH R01DK018849May 1, 1976 - Jun 30, 2021
    Role: Principal Investigator
    REGULATION OF NEUROPEPTIDE BIOSYNTHESIS
    NIH R01AM018849May 1, 1976 - Jun 30, 1989
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Emerging mechanisms of regulation for endoplasmic/sarcoplasmic reticulum Ca2+ stores by secretory pathway kinase FAM20C. Curr Opin Chem Biol. 2023 06; 74:102279. Mayfield JE, Dixon JE. PMID: 36966700.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    2. Hippo pathway regulation by phosphatidylinositol transfer protein and phosphoinositides. Nat Chem Biol. 2022 10; 18(10):1076-1086. Li FL, Fu V, Liu G, Tang T, Konradi AW, Peng X, Kemper E, Cravatt BF, Franklin JM, Wu Z, Mayfield J, Dixon JE, Gerwick WH, Guan KL. PMID: 35788180.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    3. The ABCs of the atypical Fam20 secretory pathway kinases. J Biol Chem. 2021 Jan-Jun; 296:100267. Worby CA, Mayfield JE, Pollak AJ, Dixon JE, Banerjee S. PMID: 33759783; PMCID: PMC7948968.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    4. The stress-responsive kinase DYRK2 activates heat shock factor 1 promoting resistance to proteotoxic stress. Cell Death Differ. 2021 05; 28(5):1563-1578. Moreno R, Banerjee S, Jackson AW, Quinn J, Baillie G, Dixon JE, Dinkova-Kostova AT, Edwards J, de la Vega L. PMID: 33268814; PMCID: PMC8166837.
      View in: PubMed   Mentions: 13     Fields:    
    5. POMK regulates dystroglycan function via LARGE1-mediated elongation of matriglycan. Elife. 2020 09 25; 9. Walimbe AS, Okuma H, Joseph S, Yang T, Yonekawa T, Hord JM, Venzke D, Anderson ME, Torelli S, Manzur A, Devereaux M, Cuellar M, Prouty S, Ocampo Landa S, Yu L, Xiao J, Dixon JE, Muntoni F, Campbell KP. PMID: 32975514; PMCID: PMC7556876.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    6. Reversible phosphorylation of Rpn1 regulates 26S proteasome assembly and function. Proc Natl Acad Sci U S A. 2020 01 07; 117(1):328-336. Liu X, Xiao W, Zhang Y, Wiley SE, Zuo T, Zheng Y, Chen N, Chen L, Wang X, Zheng Y, Huang L, Lin S, Murphy AN, Dixon JE, Xu P, Guo X. PMID: 31843888; PMCID: PMC6955308.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    7. Inhibition of dual-specificity tyrosine phosphorylation-regulated kinase 2 perturbs 26S proteasome-addicted neoplastic progression. Proc Natl Acad Sci U S A. 2019 12 03; 116(49):24881-24891. Banerjee S, Wei T, Wang J, Lee JJ, Gutierrez HL, Chapman O, Wiley SE, Mayfield JE, Tandon V, Juarez EF, Chavez L, Liang R, Sah RL, Costello C, Mesirov JP, de la Vega L, Cooper KL, Dixon JE, Xiao J, Lei X. PMID: 31754034; PMCID: PMC6900511.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    8. Ancestral roles of the Fam20C family of secreted protein kinases revealed in C. elegans. J Cell Biol. 2019 11 04; 218(11):3795-3811. Gerson-Gurwitz A, Worby CA, Lee KY, Khaliullin R, Bouffard J, Cheerambathur D, Oegema K, Cram EJ, Dixon JE, Desai A. PMID: 31541016; PMCID: PMC6829671.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    9. Reversible phosphorylation: a birthday tribute to Herb Tabor. J Biol Chem. 2019 02 01; 294(5):1638-1642. Worby CA, Dixon JE. PMID: 30710011; PMCID: PMC6364790.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    10. A secretory pathway kinase regulates sarcoplasmic reticulum Ca2+ homeostasis and protects against heart failure. Elife. 2018 12 06; 7. Pollak AJ, Liu C, Gudlur A, Mayfield JE, Dalton ND, Gu Y, Chen J, Heller Brown J, Hogan PG, Wiley SE, Peterson KL, Dixon JE. PMID: 30520731; PMCID: PMC6298778.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    11. Enzymatic Phosphorylation of Ser in a Type I Collagen Peptide. Biophys J. 2018 12 18; 115(12):2327-2335. Qiu Y, Poppleton E, Mekkat A, Yu H, Banerjee S, Wiley SE, Dixon JE, Kaplan DL, Lin YS, Brodsky B. PMID: 30527445; PMCID: PMC6302033.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    12. Ancient drug curcumin impedes 26S proteasome activity by direct inhibition of dual-specificity tyrosine-regulated kinase 2. Proc Natl Acad Sci U S A. 2018 08 07; 115(32):8155-8160. Banerjee S, Ji C, Mayfield JE, Goel A, Xiao J, Dixon JE, Guo X. PMID: 29987021; PMCID: PMC6094102.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    13. Structure and evolution of the Fam20 kinases. Nat Commun. 2018 03 23; 9(1):1218. Zhang H, Zhu Q, Cui J, Wang Y, Chen MJ, Guo X, Tagliabracci VS, Dixon JE, Xiao J. PMID: 29572475; PMCID: PMC5865150.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    14. Phosphorylation of serine96 of histidine-rich calcium-binding protein by the Fam20C kinase functions to prevent cardiac arrhythmia. Proc Natl Acad Sci U S A. 2017 08 22; 114(34):9098-9103. Pollak AJ, Haghighi K, Kunduri S, Arvanitis DA, Bidwell PA, Liu GS, Singh VP, Gonzalez DJ, Sanoudou D, Wiley SE, Dixon JE, Kranias EG. PMID: 28784772; PMCID: PMC5576816.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    15. Structure of Fam20A reveals a pseudokinase featuring a unique disulfide pattern and inverted ATP-binding. Elife. 2017 04 22; 6. Cui J, Zhu Q, Zhang H, Cianfrocco MA, Leschziner AE, Dixon JE, Xiao J. PMID: 28432788; PMCID: PMC5413348.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    16. Genomics and evolution of protein phosphatases. Sci Signal. 2017 Apr 11; 10(474). Chen MJ, Dixon JE, Manning G. PMID: 28400531.
      View in: PubMed   Mentions: 113     Fields:    Translation:HumansAnimalsCells
    17. Molecular Details Underlying Dynamic Structures and Regulation of the Human 26S Proteasome. Mol Cell Proteomics. 2017 05; 16(5):840-854. Wang X, Cimermancic P, Yu C, Schweitzer A, Chopra N, Engel JL, Greenberg C, Huszagh AS, Beck F, Sakata E, Yang Y, Novitsky EJ, Leitner A, Nanni P, Kahraman A, Guo X, Dixon JE, Rychnovsky SD, Aebersold R, Baumeister W, Sali A, Huang L. PMID: 28292943; PMCID: PMC5417825.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    18. Structure of protein O-mannose kinase reveals a unique active site architecture. Elife. 2016 11 23; 5. Zhu Q, Venzke D, Walimbe AS, Anderson ME, Fu Q, Kinch LN, Wang W, Chen X, Grishin NV, Huang N, Yu L, Dixon JE, Campbell KP, Xiao J. PMID: 27879205; PMCID: PMC5142810.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    19. Phosphorylation of spore coat proteins by a family of atypical protein kinases. Proc Natl Acad Sci U S A. 2016 06 21; 113(25):E3482-91. Nguyen KB, Sreelatha A, Durrant ES, Lopez-Garrido J, Muszewska A, Dudkiewicz M, Grynberg M, Yee S, Pogliano K, Tomchick DR, Pawlowski K, Dixon JE, Tagliabracci VS. PMID: 27185916; PMCID: PMC4922149.
      View in: PubMed   Mentions: 34     Fields:    Translation:Cells
    20. Chirality of nanophotonic waveguide with embedded quantum emitter for unidirectional spin transfer. Nat Commun. 2016 Mar 31; 7:11183. Coles RJ, Price DM, Dixon JE, Royall B, Clarke E, Kok P, Skolnick MS, Fox AM, Makhonin MN. PMID: 27029961; PMCID: PMC4821884.
      View in: PubMed   Mentions: 9     Fields:    
    21. The 26S proteasome: A cell cycle regulator regulated by cell cycle. Cell Cycle. 2016; 15(7):875-6. Guo X, Dixon JE. PMID: 26940127; PMCID: PMC4889267.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    22. Site-specific proteasome phosphorylation controls cell proliferation and tumorigenesis. Nat Cell Biol. 2016 Feb; 18(2):202-12. Guo X, Wang X, Wang Z, Banerjee S, Yang J, Huang L, Dixon JE. PMID: 26655835; PMCID: PMC4844191.
      View in: PubMed   Mentions: 88     Fields:    Translation:HumansAnimalsCells
    23. A Single Kinase Generates the Majority of the Secreted Phosphoproteome. Cell. 2015 Jun 18; 161(7):1619-32. Tagliabracci VS, Wiley SE, Guo X, Kinch LN, Durrant E, Wen J, Xiao J, Cui J, Nguyen KB, Engel JL, Coon JJ, Grishin N, Pinna LA, Pagliarini DJ, Dixon JE. PMID: 26091039; PMCID: PMC4963185.
      View in: PubMed   Mentions: 157     Fields:    Translation:HumansCells
    24. A new role for sphingosine: Up-regulation of Fam20C, the genuine casein kinase that phosphorylates secreted proteins. Biochim Biophys Acta. 2015 Oct; 1854(10 Pt B):1718-26. Cozza G, Salvi M, Banerjee S, Tibaldi E, Tagliabracci VS, Dixon JE, Pinna LA. PMID: 25936777.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    25. A potent and selective inhibitor for the UBLCP1 proteasome phosphatase. Bioorg Med Chem. 2015 Jun 15; 23(12):2798-809. He Y, Guo X, Yu ZH, Wu L, Gunawan AM, Zhang Y, Dixon JE, Zhang ZY. PMID: 25907364; PMCID: PMC4451428.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    26. A secretory kinase complex regulates extracellular protein phosphorylation. Elife. 2015 Mar 19; 4:e06120. Cui J, Xiao J, Tagliabracci VS, Wen J, Rahdar M, Dixon JE. PMID: 25789606; PMCID: PMC4421793.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimalsCells
    27. Xylose phosphorylation functions as a molecular switch to regulate proteoglycan biosynthesis. Proc Natl Acad Sci U S A. 2014 Nov 04; 111(44):15723-8. Wen J, Xiao J, Rahdar M, Choudhury BP, Cui J, Taylor GS, Esko JD, Dixon JE. PMID: 25331875; PMCID: PMC4226115.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansCells
    28. Unpacking the unfolded protein response. Cell. 2014 Sep 11; 158(6):1221-1224. Worby CA, Dixon JE. PMID: 25215479.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    29. A secreted tyrosine kinase acts in the extracellular environment. Cell. 2014 Aug 28; 158(5):1033-1044. Bordoli MR, Yum J, Breitkopf SB, Thon JN, Italiano JE, Xiao J, Worby C, Wong SK, Lin G, Edenius M, Keller TL, Asara JM, Dixon JE, Yeo CY, Whitman M. PMID: 25171405; PMCID: PMC4149754.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansAnimalsCells
    30. Dynamic regulation of FGF23 by Fam20C phosphorylation, GalNAc-T3 glycosylation, and furin proteolysis. Proc Natl Acad Sci U S A. 2014 Apr 15; 111(15):5520-5. Tagliabracci VS, Engel JL, Wiley SE, Xiao J, Gonzalez DJ, Nidumanda Appaiah H, Koller A, Nizet V, White KE, Dixon JE. PMID: 24706917; PMCID: PMC3992636.
      View in: PubMed   Mentions: 147     Fields:    Translation:HumansCells
    31. Phenol soluble modulin (PSM) variants of community-associated methicillin-resistant Staphylococcus aureus (MRSA) captured using mass spectrometry-based molecular networking. Mol Cell Proteomics. 2014 May; 13(5):1262-72. Gonzalez DJ, Vuong L, Gonzalez IS, Keller N, McGrosso D, Hwang JH, Hung J, Zinkernagel A, Dixon JE, Dorrestein PC, Nizet V. PMID: 24567418; PMCID: PMC4014283.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    32. ZFX controls propagation and prevents differentiation of acute T-lymphoblastic and myeloid leukemia. Cell Rep. 2014 Feb 13; 6(3):528-40. Weisberg SP, Smith-Raska MR, Esquilin JM, Zhang J, Arenzana TL, Lau CM, Churchill M, Pan H, Klinakis A, Dixon JE, Mirny LA, Mukherjee S, Reizis B. PMID: 24485662; PMCID: PMC3936793.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    33. Spatial control of phospholipid flux restricts endoplasmic reticulum sheet formation to allow nuclear envelope breakdown. Genes Dev. 2014 Jan 15; 28(2):121-6. Bahmanyar S, Biggs R, Schuh AL, Desai A, Müller-Reichert T, Audhya A, Dixon JE, Oegema K. PMID: 24449268; PMCID: PMC3909786.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    34. PTEN. Annu Rev Biochem. 2014; 83:641-69. Worby CA, Dixon JE. PMID: 24905788.
      View in: PubMed   Mentions: 245     Fields:    Translation:HumansAnimalsCells
    35. Recognition of the protein kinase AVRPPHB SUSCEPTIBLE1 by the disease resistance protein RESISTANCE TO PSEUDOMONAS SYRINGAE5 is dependent on s-acylation and an exposed loop in AVRPPHB SUSCEPTIBLE1. Plant Physiol. 2014 Jan; 164(1):340-51. Qi D, Dubiella U, Kim SH, Sloss DI, Dowen RH, Dixon JE, Innes RW. PMID: 24225654; PMCID: PMC3875812.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    36. The EBAX-type Cullin-RING E3 ligase and Hsp90 guard the protein quality of the SAX-3/Robo receptor in developing neurons. Neuron. 2013 Sep 04; 79(5):903-16. Wang Z, Hou Y, Guo X, van der Voet M, Boxem M, Dixon JE, Chisholm AD, Jin Y. PMID: 24012004; PMCID: PMC3779136.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    37. Response to Wang et al.: Secreted protein kinases? Trends Biochem Sci. 2013 Sep; 38(9):425. Tagliabracci VS, Pinna LA, Dixon JE. PMID: 23992948.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    38. Phosphorylation of substrates destined for secretion by the Fam20 kinases. Biochem Soc Trans. 2013 Aug; 41(4):1061-5. Tagliabracci VS, Xiao J, Dixon JE. PMID: 23863179.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    39. Crystal structure of the Golgi casein kinase. Proc Natl Acad Sci U S A. 2013 Jun 25; 110(26):10574-9. Xiao J, Tagliabracci VS, Wen J, Kim SA, Dixon JE. PMID: 23754375; PMCID: PMC3696822.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    40. Wolfram Syndrome protein, Miner1, regulates sulphydryl redox status, the unfolded protein response, and Ca2+ homeostasis. EMBO Mol Med. 2013 Jun; 5(6):904-18. Wiley SE, Andreyev AY, Divakaruni AS, Karisch R, Perkins G, Wall EA, van der Geer P, Chen YF, Tsai TF, Simon MI, Neel BG, Dixon JE, Murphy AN. PMID: 23703906; PMCID: PMC3779451.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    41. Identification of a mammalian-type phosphatidylglycerophosphate phosphatase in the Eubacterium Rhodopirellula baltica. J Biol Chem. 2013 Feb 15; 288(7):5176-85. Teh PG, Chen MJ, Engel JL, Worby CA, Manning G, Dixon JE, Zhang J. PMID: 23293031; PMCID: PMC3576122.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    42. Secreted protein kinases. Trends Biochem Sci. 2013 Mar; 38(3):121-30. Tagliabracci VS, Pinna LA, Dixon JE. PMID: 23276407; PMCID: PMC3582740.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansAnimals
    43. Widespread dynamic DNA methylation in response to biotic stress. Proc Natl Acad Sci U S A. 2012 Aug 07; 109(32):E2183-91. Dowen RH, Pelizzola M, Schmitz RJ, Lister R, Dowen JM, Nery JR, Dixon JE, Ecker JR. PMID: 22733782; PMCID: PMC3420206.
      View in: PubMed   Mentions: 409     Fields:    Translation:AnimalsCells
    44. Secreted kinase phosphorylates extracellular proteins that regulate biomineralization. Science. 2012 Jun 01; 336(6085):1150-3. Tagliabracci VS, Engel JL, Wen J, Wiley SE, Worby CA, Kinch LN, Xiao J, Grishin NV, Dixon JE. PMID: 22582013; PMCID: PMC3754843.
      View in: PubMed   Mentions: 216     Fields:    Translation:HumansAnimalsCells
    45. Novel phenol-soluble modulin derivatives in community-associated methicillin-resistant Staphylococcus aureus identified through imaging mass spectrometry. J Biol Chem. 2012 Apr 20; 287(17):13889-98. Gonzalez DJ, Okumura CY, Hollands A, Kersten R, Akong-Moore K, Pence MA, Malone CL, Derieux J, Moore BS, Horswill AR, Dixon JE, Dorrestein PC, Nizet V. PMID: 22371493; PMCID: PMC3340166.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    46. Nuclear envelope phosphatase 1-regulatory subunit 1 (formerly TMEM188) is the metazoan Spo7p ortholog and functions in the lipin activation pathway. J Biol Chem. 2012 Jan 27; 287(5):3123-37. Han S, Bahmanyar S, Zhang P, Grishin N, Oegema K, Crooke R, Graham M, Reue K, Dixon JE, Goodman JM. PMID: 22134922; PMCID: PMC3283218.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    47. UBLCP1 is a 26S proteasome phosphatase that regulates nuclear proteasome activity. Proc Natl Acad Sci U S A. 2011 Nov 15; 108(46):18649-54. Guo X, Engel JL, Xiao J, Tagliabracci VS, Wang X, Huang L, Dixon JE. PMID: 21949367; PMCID: PMC3219150.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    48. Comparative analysis of Histophilus somni immunoglobulin-binding protein A (IbpA) with other fic domain-containing enzymes reveals differences in substrate and nucleotide specificities. J Biol Chem. 2011 Sep 16; 286(37):32834-42. Mattoo S, Durrant E, Chen MJ, Xiao J, Lazar CS, Manning G, Dixon JE, Worby CA. PMID: 21795713; PMCID: PMC3173180.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    49. Structural and functional analysis of PTPMT1, a phosphatase required for cardiolipin synthesis. Proc Natl Acad Sci U S A. 2011 Jul 19; 108(29):11860-5. Xiao J, Engel JL, Zhang J, Chen MJ, Manning G, Dixon JE. PMID: 21730175; PMCID: PMC3142007.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    50. Mitochondrial phosphatase PTPMT1 is essential for cardiolipin biosynthesis. Cell Metab. 2011 Jun 08; 13(6):690-700. Zhang J, Guan Z, Murphy AN, Wiley SE, Perkins GA, Worby CA, Engel JL, Heacock P, Nguyen OK, Wang JH, Raetz CR, Dowhan W, Dixon JE. PMID: 21641550; PMCID: PMC3119201.
      View in: PubMed   Mentions: 96     Fields:    Translation:AnimalsCells
    51. Expansion of type II CAAX proteases reveals evolutionary origin of γ-secretase subunit APH-1. J Mol Biol. 2011 Jul 01; 410(1):18-26. Pei J, Mitchell DA, Dixon JE, Grishin NV. PMID: 21570408; PMCID: PMC3155266.
      View in: PubMed   Mentions: 39     Fields:    Translation:Cells
    52. Glycogen synthase: an old enzyme with a new trick. Cell Metab. 2011 Mar 02; 13(3):233-4. Worby CA, Dixon JE. PMID: 21356510.
      View in: PubMed   Mentions:    Fields:    
    53. Voltage-sensing phosphatase: its molecular relationship with PTEN. Physiology (Bethesda). 2011 Feb; 26(1):6-13. Okamura Y, Dixon JE. PMID: 21357898.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    54. Structural basis of Fic-mediated adenylylation. Nat Struct Mol Biol. 2010 Aug; 17(8):1004-10. Xiao J, Worby CA, Mattoo S, Sankaran B, Dixon JE. PMID: 20622875; PMCID: PMC2920259.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    55. Clostridiolysin S, a post-translationally modified biotoxin from Clostridium botulinum. J Biol Chem. 2010 Sep 03; 285(36):28220-8. Gonzalez DJ, Lee SW, Hensler ME, Markley AL, Dahesh S, Mitchell DA, Bandeira N, Nizet V, Dixon JE, Dorrestein PC. PMID: 20581111; PMCID: PMC2934687.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    56. Climate change and the integrity of science. Science. 2010 May 07; 328(5979):689-90. Gleick PH, Adams RM, Amasino RM, Anders E, Anderson DJ, Anderson WW, Anselin LE, Arroyo MK, Asfaw B, Ayala FJ, Bax A, Bebbington AJ, Bell G, Bennett MV, Bennetzen JL, Berenbaum MR, Berlin OB, Bjorkman PJ, Blackburn E, Blamont JE, Botchan MR, Boyer JS, Boyle EA, Branton D, Briggs SP, Briggs WR, Brill WJ, Britten RJ, Broecker WS, Brown JH, Brown PO, Brunger AT, Cairns J, Canfield DE, Carpenter SR, Carrington JC, Cashmore AR, Castilla JC, Cazenave A, Chapin FS, Ciechanover AJ, Clapham DE, Clark WC, Clayton RN, Coe MD, Conwell EM, Cowling EB, Cowling RM, Cox CS, Croteau RB, Crothers DM, Crutzen PJ, Daily GC, Dalrymple GB, Dangl JL, Darst SA, Davies DR, Davis MB, De Camilli PV, Dean C, DeFries RS, Deisenhofer J, Delmer DP, DeLong EF, DeRosier DJ, Diener TO, Dirzo R, Dixon JE, Donoghue MJ, Doolittle RF, Dunne T, Ehrlich PR, Eisenstadt SN, Eisner T, Emanuel KA, Englander SW, Ernst WG, Falkowski PG, Feher G, Ferejohn JA, Fersht A, Fischer EH, Fischer R, Flannery KV, Frank J, Frey PA, Fridovich I, Frieden C, Futuyma DJ, Gardner WR, Garrett CJ, Gilbert W, Goldberg RB, Goodenough WH, Goodman CS, Goodman M, Greengard P, Hake S, Hammel G, Hanson S, Harrison SC, Hart SR, Hartl DL, Haselkorn R, Hawkes K, Hayes JM, Hille B, Hökfelt T, House JS, Hout M, Hunten DM, Izquierdo IA, Jagendorf AT, Janzen DH, Jeanloz R, Jencks CS, Jury WA, Kaback HR, Kailath T, Kay P, Kay SA, Kennedy D, Kerr A, Kessler RC, Khush GS, Kieffer SW, Kirch PV, Kirk K, Kivelson MG, Klinman JP, Klug A, Knopoff L, Kornberg H, Kutzbach JE, Lagarias JC, Lambeck K, Landy A, Langmuir CH, Larkins BA, Le Pichon XT, Lenski RE, Leopold EB, Levin SA, Levitt M, Likens GE, Lippincott-Schwartz J, Lorand L, Lovejoy CO, Lynch M, Mabogunje AL, Malone TF, Manabe S, Marcus J, Massey DS, McWilliams JC, Medina E, Melosh HJ, Meltzer DJ, Michener CD, Miles EL, Mooney HA, Moore PB, Morel FM, Mosley-Thompson ES, Moss B, Munk WH, Myers N, Nair GB, Nathans J, Nester EW, Nicoll RA, Novick RP, O'Connell JF, Olsen PE, Opdyke ND, Oster GF, Ostrom E, Pace NR, Paine RT, Palmiter RD, Pedlosky J, Petsko GA, Pettengill GH, Philander SG, Piperno DR, Pollard TD, Price PB, Reichard PA, Reskin BF, Ricklefs RE, Rivest RL, Roberts JD, Romney AK, Rossmann MG, Russell DW, Rutter WJ, Sabloff JA, Sagdeev RZ, Sahlins MD, Salmond A, Sanes JR, Schekman R, Schellnhuber J, Schindler DW, Schmitt J, Schneider SH, Schramm VL, Sederoff RR, Shatz CJ, Sherman F, Sidman RL, Sieh K, Simons EL, Singer BH, Singer MF, Skyrms B, Sleep NH, Smith BD, Snyder SH, Sokal RR, Spencer CS, Steitz TA, Strier KB, Südhof TC, Taylor SS, Terborgh J, Thomas DH, Thompson LG, Tjian RT, Turner MG, Uyeda S, Valentine JW, Valentine JS, Van Etten JL, van Holde KE, Vaughan M, Verba S, von Hippel PH, Wake DB, Walker A, Walker JE, Watson EB, Watson PJ, Weigel D, Wessler SR, West-Eberhard MJ, White TD, Wilson WJ, Wolfenden RV, Wood JA, Woodwell GM, Wright HE, Wu C, Wunsch C, Zoback ML. PMID: 20448167; PMCID: PMC5125622.
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    57. Structural and functional analysis of the phosphoryl transfer reaction mediated by the human small C-terminal domain phosphatase, Scp1. Protein Sci. 2010 May; 19(5):974-86. Zhang M, Liu J, Kim Y, Dixon JE, Pfaff SL, Gill GN, Noel JP, Zhang Y. PMID: 20222012; PMCID: PMC2868240.
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    58. Pharmacological targeting of the mitochondrial phosphatase PTPMT1. J Pharmacol Exp Ther. 2010 May; 333(2):584-92. Doughty-Shenton D, Joseph JD, Zhang J, Pagliarini DJ, Kim Y, Lu D, Dixon JE, Casey PJ. PMID: 20167843; PMCID: PMC2872949.
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    59. Lafora disease: insights into neurodegeneration from plant metabolism. Trends Biochem Sci. 2009 Dec; 34(12):628-39. Gentry MS, Dixon JE, Worby CA. PMID: 19818631; PMCID: PMC2805077.
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    60. The fic domain: regulation of cell signaling by adenylylation. Mol Cell. 2009 Apr 10; 34(1):93-103. Worby CA, Mattoo S, Kruger RP, Corbeil LB, Koller A, Mendez JC, Zekarias B, Lazar C, Dixon JE. PMID: 19362538; PMCID: PMC2820730.
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    61. A family of bacterial cysteine protease type III effectors utilizes acylation-dependent and -independent strategies to localize to plasma membranes. J Biol Chem. 2009 Jun 05; 284(23):15867-79. Dowen RH, Engel JL, Shao F, Ecker JR, Dixon JE. PMID: 19346252; PMCID: PMC2708883.
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    62. Monitoring phosphorylation of the pyruvate dehydrogenase complex. Anal Biochem. 2009 Jun 15; 389(2):157-64. Rardin MJ, Wiley SE, Naviaux RK, Murphy AN, Dixon JE. PMID: 19341700; PMCID: PMC2713743.
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    63. Structural and functional dissection of the heterocyclic peptide cytotoxin streptolysin S. J Biol Chem. 2009 May 08; 284(19):13004-12. Mitchell DA, Lee SW, Pence MA, Markley AL, Limm JD, Nizet V, Dixon JE. PMID: 19286651; PMCID: PMC2676033.
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    64. Distinguishing mitochondrial inner membrane orientation of dual specific phosphatase 18 and 21. Methods Enzymol. 2009; 457:275-87. Rardin MJ, Taylor GS, Dixon JE. PMID: 19426873.
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    65. Chapter 13 Localization and function of the 2Fe-2S outer mitochondrial membrane protein mitoNEET. Methods Enzymol. 2009; 456:233-46. Wiley SE, Rardin MJ, Dixon JE. PMID: 19348892.
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    66. Structure and function of Salmonella SifA indicate that its interactions with SKIP, SseJ, and RhoA family GTPases induce endosomal tubulation. Cell Host Microbe. 2008 Nov 13; 4(5):434-46. Ohlson MB, Huang Z, Alto NM, Blanc MP, Dixon JE, Chai J, Miller SI. PMID: 18996344; PMCID: PMC2658612.
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    67. Protection of mice against H. somni septicemia by vaccination with recombinant immunoglobulin binding protein subunits. Vaccine. 2008 Aug 18; 26(35):4506-12. Geertsema RS, Worby C, Kruger RP, Tagawa Y, Russo R, Herdman DS, Lo K, Kimball RA, Dixon J, Corbeil LB. PMID: 18590787; PMCID: PMC2659705.
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    68. A voltage-sensing phosphatase, Ci-VSP, which shares sequence identity with PTEN, dephosphorylates phosphatidylinositol 4,5-bisphosphate. Proc Natl Acad Sci U S A. 2008 Jun 10; 105(23):7970-5. Iwasaki H, Murata Y, Kim Y, Hossain MI, Worby CA, Dixon JE, McCormack T, Sasaki T, Okamura Y. PMID: 18524949; PMCID: PMC2430346.
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    70. Discovery of a widely distributed toxin biosynthetic gene cluster. Proc Natl Acad Sci U S A. 2008 Apr 15; 105(15):5879-84. Lee SW, Mitchell DA, Markley AL, Hensler ME, Gonzalez D, Wohlrab A, Dorrestein PC, Nizet V, Dixon JE. PMID: 18375757; PMCID: PMC2311365.
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    71. Loss of the inactive myotubularin-related phosphatase Mtmr13 leads to a Charcot-Marie-Tooth 4B2-like peripheral neuropathy in mice. Proc Natl Acad Sci U S A. 2008 Mar 25; 105(12):4916-21. Robinson FL, Niesman IR, Beiswenger KK, Dixon JE. PMID: 18349142; PMCID: PMC2290800.
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    72. Subversion of myosin function by E. coli. Dev Cell. 2008 Jan; 14(1):8-10. Mattoo S, Alto NM, Dixon JE. PMID: 18194648.
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    73. Analysis of Rho-GTPase mimicry by a family of bacterial type III effector proteins. Methods Enzymol. 2008; 439:131-43. Alto NM, Dixon JE. PMID: 18374161.
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    74. Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG). J Biol Chem. 2008 Feb 15; 283(7):4069-76. Worby CA, Gentry MS, Dixon JE. PMID: 18070875; PMCID: PMC2251628.
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    75. A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's disease. Genes Dev. 2007 Oct 01; 21(19):2399-409. Cheng A, Zhang M, Gentry MS, Worby CA, Dixon JE, Saltiel AR. PMID: 17908927; PMCID: PMC1993871.
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    77. MitoNEET is a uniquely folded 2Fe 2S outer mitochondrial membrane protein stabilized by pioglitazone. Proc Natl Acad Sci U S A. 2007 Sep 04; 104(36):14342-7. Paddock ML, Wiley SE, Axelrod HL, Cohen AE, Roy M, Abresch EC, Capraro D, Murphy AN, Nechushtai R, Dixon JE, Jennings PA. PMID: 17766440; PMCID: PMC1963346.
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    78. Zebrafish pten genes have overlapping and non-redundant functions in tumorigenesis and embryonic development. Oncogene. 2008 Feb 14; 27(8):1079-86. Faucherre A, Taylor GS, Overvoorde J, Dixon JE, Hertog Jd. PMID: 17704803.
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    79. Interactions of bacterial effector proteins with host proteins. Curr Opin Immunol. 2007 Aug; 19(4):392-401. Mattoo S, Lee YM, Dixon JE. PMID: 17662586.
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    80. The phosphatase laforin crosses evolutionary boundaries and links carbohydrate metabolism to neuronal disease. J Cell Biol. 2007 Jul 30; 178(3):477-88. Gentry MS, Dowen RH, Worby CA, Mattoo S, Ecker JR, Dixon JE. PMID: 17646401; PMCID: PMC2064834.
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    81. A reply from Howard Hughes Medical Institute (HHMI). J Cell Biol. 2007 Jul 30; 178(3):343; discussion 343. Cech T, Dixon J, Meehan A, Briggs J, Rhodes C. PMID: 17646394; PMCID: PMC2064853.
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    83. Identification of a molecular target for the Yersinia protein kinase A. Mol Cell. 2007 May 25; 26(4):465-77. Navarro L, Koller A, Nordfelth R, Wolf-Watz H, Taylor S, Dixon JE. PMID: 17531806.
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    84. A conserved phosphatase cascade that regulates nuclear membrane biogenesis. Proc Natl Acad Sci U S A. 2007 Apr 17; 104(16):6596-601. Kim Y, Gentry MS, Harris TE, Wiley SE, Lawrence JC, Dixon JE. PMID: 17420445; PMCID: PMC1871831.
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    86. The Sorcerer II Global Ocean Sampling expedition: expanding the universe of protein families. PLoS Biol. 2007 Mar; 5(3):e16. Yooseph S, Sutton G, Rusch DB, Halpern AL, Williamson SJ, Remington K, Eisen JA, Heidelberg KB, Manning G, Li W, Jaroszewski L, Cieplak P, Miller CS, Li H, Mashiyama ST, Joachimiak MP, van Belle C, Chandonia JM, Soergel DA, Zhai Y, Natarajan K, Lee S, Raphael BJ, Bafna V, Friedman R, Brenner SE, Godzik A, Eisenberg D, Dixon JE, Taylor SS, Strausberg RL, Frazier M, Venter JC. PMID: 17355171; PMCID: PMC1821046.
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    89. Myotubularin phosphatases: policing 3-phosphoinositides. Trends Cell Biol. 2006 Aug; 16(8):403-12. Robinson FL, Dixon JE. PMID: 16828287.
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    90. The p53-targeting human phosphatase hCdc14A interacts with the Cdk1/cyclin B complex and is differentially expressed in human cancers. Mol Cancer. 2006 Jun 19; 5:25. Paulsen MT, Starks AM, Derheimer FA, Hanasoge S, Li L, Dixon JE, Ljungman M. PMID: 16784539; PMCID: PMC1524803.
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    91. Microbiology. Bacteria seize control by acetylating host proteins. Science. 2006 May 26; 312(5777):1150-1. Worby CA, Dixon JE. PMID: 16731519.
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    92. Identification of a bacterial type III effector family with G protein mimicry functions. Cell. 2006 Jan 13; 124(1):133-45. Alto NM, Shao F, Lazar CS, Brost RL, Chua G, Mattoo S, McMahon SA, Ghosh P, Hughes TR, Boone C, Dixon JE. PMID: 16413487.
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    93. Molecular basis for substrate recognition by MTMR2, a myotubularin family phosphoinositide phosphatase. Proc Natl Acad Sci U S A. 2006 Jan 24; 103(4):927-32. Begley MJ, Taylor GS, Brock MA, Ghosh P, Woods VL, Dixon JE. PMID: 16410353; PMCID: PMC1347996.
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    94. Identification of otubain 1 as a novel substrate for the Yersinia protein kinase using chemical genetics and mass spectrometry. FEBS Lett. 2006 Jan 09; 580(1):179-83. Juris SJ, Shah K, Shokat K, Dixon JE, Vacratsis PO. PMID: 16364312.
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    95. Mitochondrial modulation: reversible phosphorylation takes center stage? Trends Biochem Sci. 2006 Jan; 31(1):26-34. Pagliarini DJ, Dixon JE. PMID: 16337125.
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    98. Involvement of a mitochondrial phosphatase in the regulation of ATP production and insulin secretion in pancreatic beta cells. Mol Cell. 2005 Jul 22; 19(2):197-207. Pagliarini DJ, Wiley SE, Kimple ME, Dixon JR, Kelly P, Worby CA, Casey PJ, Dixon JE. PMID: 16039589.
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    99. The phosphoinositide-3-phosphatase MTMR2 associates with MTMR13, a membrane-associated pseudophosphatase also mutated in type 4B Charcot-Marie-Tooth disease. J Biol Chem. 2005 Sep 09; 280(36):31699-707. Robinson FL, Dixon JE. PMID: 15998640.
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    101. Functions of the Yersinia effector proteins in inhibiting host immune responses. Curr Opin Microbiol. 2005 Feb; 8(1):21-7. Navarro L, Alto NM, Dixon JE. PMID: 15694853.
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    102. A PTEN-like phosphatase with a novel substrate specificity. J Biol Chem. 2004 Sep 10; 279(37):38590-6. Pagliarini DJ, Worby CA, Dixon JE. PMID: 15247229.
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    103. Protein tyrosine phosphatases in the human genome. Cell. 2004 Jun 11; 117(6):699-711. Alonso A, Sasin J, Bottini N, Friedberg I, Friedberg I, Osterman A, Godzik A, Hunter T, Dixon J, Mustelin T. PMID: 15186772.
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    104. Suppression of a phosphatidylinositol 3-kinase signal by a specific spliced variant of Drosophila PTEN. FEBS Lett. 2004 May 07; 565(1-3):43-7. Maehama T, Kosaka N, Okahara F, Takeuchi K, Umeda M, Dixon JE, Kanaho Y. PMID: 15135050.
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    105. RNA interference in cultured Drosophila cells. Curr Protoc Mol Biol. 2004 Feb; Chapter 26:Unit 26.5. Worby CA, Dixon JE. PMID: 18265350.
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    106. Assaying phosphoinositide phosphatases. Methods Mol Biol. 2004; 284:217-27. Taylor GS, Dixon JE. PMID: 15173619.
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    107. The crystal structure of Pseudomonas avirulence protein AvrPphB: a papain-like fold with a distinct substrate-binding site. Proc Natl Acad Sci U S A. 2004 Jan 06; 101(1):302-7. Zhu M, Shao F, Innes RW, Dixon JE, Xu Z. PMID: 14694194; PMCID: PMC314180.
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    108. Crystal structure of a phosphoinositide phosphatase, MTMR2: insights into myotubular myopathy and Charcot-Marie-Tooth syndrome. Mol Cell. 2003 Dec; 12(6):1391-402. Begley MJ, Taylor GS, Kim SA, Veine DM, Dixon JE, Stuckey JA. PMID: 14690594.
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    109. Cleavage of Arabidopsis PBS1 by a bacterial type III effector. Science. 2003 Aug 29; 301(5637):1230-3. Shao F, Golstein C, Ade J, Stoutemyer M, Dixon JE, Innes RW. PMID: 12947197.
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    110. A PTEN-related 5-phosphatidylinositol phosphatase localized in the Golgi. J Biol Chem. 2003 Oct 10; 278(41):39866-73. Merlot S, Meili R, Pagliarini DJ, Maehama T, Dixon JE, Firtel RA. PMID: 12878591.
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    122. Myotubularin and MTMR2, phosphatidylinositol 3-phosphatases mutated in myotubular myopathy and type 4B Charcot-Marie-Tooth disease. J Biol Chem. 2002 Feb 08; 277(6):4526-31. Kim SA, Taylor GS, Torgersen KM, Dixon JE. PMID: 11733541.
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    123. PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy. J Biol Chem. 2002 Feb 15; 277(7):5484-9. Mayo LD, Dixon JE, Durden DL, Tonks NK, Donner DB. PMID: 11729185.
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    124. The sorting nexin, DSH3PX1, connects the axonal guidance receptor, Dscam, to the actin cytoskeleton. J Biol Chem. 2001 Nov 09; 276(45):41782-9. Worby CA, Simonson-Leff N, Clemens JC, Kruger RP, Muda M, Dixon JE. PMID: 11546816.
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    125. RNA interference of gene expression (RNAi) in cultured Drosophila cells. Sci STKE. 2001 Aug 14; 2001(95):pl1. Worby CA, Simonson-Leff N, Dixon JE. PMID: 11752672.
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    126. Phoxy lipids: revealing PX domains as phosphoinositide binding modules. Cell. 2001 Jun 29; 105(7):817-20. Wishart MJ, Taylor GS, Dixon JE. PMID: 11439176.
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    127. The PTEN tumor suppressor protein inhibits tumor necrosis factor-induced nuclear factor kappa B activity. J Biol Chem. 2001 Jul 20; 276(29):27740-4. Gustin JA, Maehama T, Dixon JE, Donner DB. PMID: 11356844.
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    128. A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1. Proc Natl Acad Sci U S A. 2001 Apr 10; 98(8):4640-5. Ozes ON, Akca H, Mayo LD, Gustin JA, Maehama T, Dixon JE, Donner DB. PMID: 11287630; PMCID: PMC31887.
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    129. ERK7 is an autoactivated member of the MAPK family. J Biol Chem. 2001 Jun 15; 276(24):21272-9. Abe MK, Kahle KT, Saelzler MP, Orth K, Dixon JE, Rosner MR. PMID: 11287416.
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    130. PTEN and myotubularin phosphoinositide phosphatases: bringing bioinformatics to the lab bench. Curr Opin Cell Biol. 2001 Apr; 13(2):172-81. Wishart MJ, Taylor GS, Slama JT, Dixon JE. PMID: 11248551.
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    131. Alternative splicing of KCNQ2 potassium channel transcripts contributes to the functional diversity of M-currents. J Physiol. 2001 Mar 01; 531(Pt 2):347-58. Pan Z, Selyanko AA, Hadley JK, Brown DA, Dixon JE, McKinnon D. PMID: 11230508; PMCID: PMC2278468.
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    132. Disruption of signaling by Yersinia effector YopJ, a ubiquitin-like protein protease. Science. 2000 Nov 24; 290(5496):1594-7. Orth K, Xu Z, Mudgett MB, Bao ZQ, Palmer LE, Bliska JB, Mangel WF, Staskawicz B, Dixon JE. PMID: 11090361.
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    133. [PTEN tumor suppressor: functions as a lipid phosphatase]. Tanpakushitsu Kakusan Koso. 2000 Oct; 45(14):2405-14. Maehama T, Dixon JE. PMID: 11051842.
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    134. A distinctive role for the Yersinia protein kinase: actin binding, kinase activation, and cytoskeleton disruption. Proc Natl Acad Sci U S A. 2000 Aug 15; 97(17):9431-6. Juris SJ, Rudolph AE, Huddler D, Orth K, Dixon JE. PMID: 10920208; PMCID: PMC16881.
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    135. The crystal structure of adenylosuccinate lyase from Pyrobaculum aerophilum reveals an intracellular protein with three disulfide bonds. J Mol Biol. 2000 Aug 11; 301(2):433-50. Toth EA, Worby C, Dixon JE, Goedken ER, Marqusee S, Yeates TO. PMID: 10926519.
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    136. Myotubularin, a protein tyrosine phosphatase mutated in myotubular myopathy, dephosphorylates the lipid second messenger, phosphatidylinositol 3-phosphate. Proc Natl Acad Sci U S A. 2000 Aug 01; 97(16):8910-5. Taylor GS, Maehama T, Dixon JE. PMID: 10900271; PMCID: PMC16795.
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    137. Drosophila Dscam is an axon guidance receptor exhibiting extraordinary molecular diversity. Cell. 2000 Jun 09; 101(6):671-84. Schmucker D, Clemens JC, Shu H, Worby CA, Xiao J, Muda M, Dixon JE, Zipursky SL. PMID: 10892653.
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    138. Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways. Proc Natl Acad Sci U S A. 2000 Jun 06; 97(12):6499-503. Clemens JC, Worby CA, Simonson-Leff N, Muda M, Maehama T, Hemmings BA, Dixon JE. PMID: 10823906; PMCID: PMC18635.
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    139. A sodium channel signaling complex: modulation by associated receptor protein tyrosine phosphatase beta. Nat Neurosci. 2000 May; 3(5):437-44. Ratcliffe CF, Qu Y, McCormick KA, Tibbs VC, Dixon JE, Scheuer T, Catterall WA. PMID: 10769382.
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    140. A sensitive assay for phosphoinositide phosphatases. Anal Biochem. 2000 Mar 15; 279(2):248-50. Maehama T, Taylor GS, Slama JT, Dixon JE. PMID: 10706796.
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    141. Form, function, and regulation of protein tyrosine phosphatases and their involvement in human diseases. Semin Immunol. 2000 Feb; 12(1):75-84. Li L, Dixon JE. PMID: 10723800.
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    142. ERBB-2 overexpression confers PI 3' kinase-dependent invasion capacity on human mammary epithelial cells. Br J Cancer. 2000 Feb; 82(3):666-74. Ignatoski KM, Maehama T, Markwart SM, Dixon JE, Livant DL, Ethier SP. PMID: 10682681; PMCID: PMC2363331.
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    143. The human Cdc14 phosphatases interact with and dephosphorylate the tumor suppressor protein p53. J Biol Chem. 2000 Jan 28; 275(4):2410-4. Li L, Ljungman M, Dixon JE. PMID: 10644693.
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    144. Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association. Cell. 1999 Oct 29; 99(3):323-34. Lee JO, Yang H, Georgescu MM, Di Cristofano A, Maehama T, Shi Y, Dixon JE, Pandolfi P, Pavletich NP. PMID: 10555148.
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    145. Inhibition of the mitogen-activated protein kinase kinase superfamily by a Yersinia effector. Science. 1999 Sep 17; 285(5435):1920-3. Orth K, Palmer LE, Bao ZQ, Stewart S, Rudolph AE, Bliska JB, Dixon JE. PMID: 10489373.
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    146. Identification of the human YVH1 protein-tyrosine phosphatase orthologue reveals a novel zinc binding domain essential for in vivo function. J Biol Chem. 1999 Aug 20; 274(34):23991-5. Muda M, Manning ER, Orth K, Dixon JE. PMID: 10446167.
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    147. Distribution and prevalence of hyperpolarization-activated cation channel (HCN) mRNA expression in cardiac tissues. Circ Res. 1999 Jul 09; 85(1):e1-6. Shi W, Wymore R, Yu H, Wu J, Wymore RT, Pan Z, Robinson RB, Dixon JE, McKinnon D, Cohen IS. PMID: 10400919.
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    148. Expression, characterization, and mutagenesis of the Yersinia pestis murine toxin, a phospholipase D superfamily member. J Biol Chem. 1999 Apr 23; 274(17):11824-31. Rudolph AE, Stuckey JA, Zhao Y, Matthews HR, Patton WA, Moss J, Dixon JE. PMID: 10207000.
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    149. Isoform-specific regulation of the sodium pump by alpha- and beta-adrenergic agonists in the guinea-pig ventricle. J Physiol. 1999 Apr 15; 516 ( Pt 2):377-83. Gao J, Wymore R, Wymore RT, Wang Y, McKinnon D, Dixon JE, Mathias RT, Cohen IS, Baldo GJ. PMID: 10087338; PMCID: PMC2269277.
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    150. Transient outward current, Ito1, is altered in cardiac memory. Circulation. 1999 Apr 13; 99(14):1898-905. Yu H, McKinnon D, Dixon JE, Gao J, Wymore R, Cohen IS, Danilo P, Shvilkin A, Anyukhovsky EP, Sosunov EA, Hara M, Rosen MR. PMID: 10199889.
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    151. PTEN: a tumour suppressor that functions as a phospholipid phosphatase. Trends Cell Biol. 1999 Apr; 9(4):125-8. Maehama T, Dixon JE. PMID: 10203785.
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    152. Crystal structure of a phospholipase D family member. Nat Struct Biol. 1999 Mar; 6(3):278-84. Stuckey JA, Dixon JE. PMID: 10074947.
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    153. His68 and His141 are critical contributors to the intersubunit catalytic site of adenylosuccinate lyase of Bacillus subtilis. Biochemistry. 1999 Jan 05; 38(1):22-32. Lee TT, Worby C, Bao ZQ, Dixon JE, Colman RF. PMID: 9890879.
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    154. Protein tyrosine phosphatases: mechanisms of catalysis and regulation. Curr Opin Chem Biol. 1998 Oct; 2(5):633-41. Denu JM, Dixon JE. PMID: 9818190.
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    155. Cloning of a mammalian elk potassium channel gene and EAG mRNA distribution in rat sympathetic ganglia. J Physiol. 1998 Sep 15; 511 ( Pt 3):675-82. Shi W, Wang HS, Pan Z, Wymore RS, Cohen IS, McKinnon D, Dixon JE. PMID: 9714851; PMCID: PMC2231163.
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    156. Catalytic mechanism of the phospholipase D superfamily proceeds via a covalent phosphohistidine intermediate. Proc Natl Acad Sci U S A. 1998 Aug 04; 95(16):9202-7. Gottlin EB, Rudolph AE, Zhao Y, Matthews HR, Dixon JE. PMID: 9689058; PMCID: PMC21316.
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    157. Gathering STYX: phosphatase-like form predicts functions for unique protein-interaction domains. Trends Biochem Sci. 1998 Aug; 23(8):301-6. Wishart MJ, Dixon JE. PMID: 9757831.
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    158. A common requirement for the catalytic activity and both SH2 domains of SHP-2 in mitogen-activated protein (MAP) kinase activation by the ErbB family of receptors. A specific role for SHP-2 in map, but not c-Jun amino-terminal kinase activation. J Biol Chem. 1998 Jul 03; 273(27):16643-6. Deb TB, Wong L, Salomon DS, Zhou G, Dixon JE, Gutkind JS, Thompson SA, Johnson GR. PMID: 9642214.
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    159. Implication of His68 in the substrate site of Bacillus subtilis adenylosuccinate lyase by mutagenesis and affinity labeling with 2-[(4-bromo-2,3-dioxobutyl)thio]adenosine 5'-monophosphate. Biochemistry. 1998 Jun 09; 37(23):8481-9. Lee TT, Worby C, Bao ZQ, Dixon JE, Colman RF. PMID: 9622500.
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    160. RNA molecules that bind to and inhibit the active site of a tyrosine phosphatase. J Biol Chem. 1998 Jun 05; 273(23):14309-14. Bell SD, Denu JM, Dixon JE, Ellington AD. PMID: 9603938.
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    161. The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem. 1998 May 29; 273(22):13375-8. Maehama T, Dixon JE. PMID: 9593664.
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    162. Identification and characterization of GFRalpha-3, a novel Co-receptor belonging to the glial cell line-derived neurotrophic receptor family. J Biol Chem. 1998 Feb 06; 273(6):3502-8. Worby CA, Vega QC, Chao HH, Seasholtz AF, Thompson RC, Dixon JE. PMID: 9452475.
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    163. Effects of sulfhydryl regents on the activity of lambda Ser/Thr phosphoprotein phosphatase and inhibition of the enzyme by zinc ion. Protein Eng. 1997 Dec; 10(12):1445-52. Zhuo S, Dixon JE. PMID: 9543006.
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    164. Expression, characterization, and crystallization of a member of the novel phospholipase D family of phosphodiesterases. Protein Sci. 1997 Dec; 6(12):2655-8. Zhao Y, Stuckey JA, Lohse DL, Dixon JE. PMID: 9416618; PMCID: PMC2143608.
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    165. A family of putative tumor suppressors is structurally and functionally conserved in humans and yeast. J Biol Chem. 1997 Nov 21; 272(47):29403-6. Li L, Ernsting BR, Wishart MJ, Lohse DL, Dixon JE. PMID: 9367992.
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    166. Differential accumulation of DPTP61F alternative transcripts: regulation of a protein tyrosine phosphatase by segmentation genes. Mech Dev. 1997 Jul; 65(1-2):19-30. Ursuliak Z, Clemens JC, Dixon JE, Price JV. PMID: 9256342.
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    167. PTP NE-6: a brain-enriched receptor-type protein tyrosine phosphatase with a divergent catalytic domain. J Neurochem. 1997 May; 68(5):1820-9. Fitzgerald LR, Walton KM, Dixon JE, Largent BL. PMID: 9109506.
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    168. Roles of aspartic acid-181 and serine-222 in intermediate formation and hydrolysis of the mammalian protein-tyrosine-phosphatase PTP1. Biochemistry. 1997 Apr 15; 36(15):4568-75. Lohse DL, Denu JM, Santoro N, Dixon JE. PMID: 9109666.
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    169. The PPS1 gene of Saccharomyces cerevisiae codes for a dual specificity protein phosphatase with a role in the DNA synthesis phase of the cell cycle. J Biol Chem. 1997 Apr 04; 272(14):9332-43. Ernsting BR, Dixon JE. PMID: 9083070.
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    170. Tissue and species distribution of mRNA for the IKr-like K+ channel, erg. Circ Res. 1997 Feb; 80(2):261-8. Wymore RS, Gintant GA, Wymore RT, Dixon JE, McKinnon D, Cohen IS. PMID: 9012748.
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    171. Identification of His141 in the active site of Bacillus subtilis adenylosuccinate lyase by affinity labeling with 6-(4-bromo-2,3-dioxobutyl)thioadenosine 5'-monophosphate. J Biol Chem. 1997 Jan 03; 272(1):458-65. Lee TT, Worby C, Dixon JE, Colman RF. PMID: 8995283.
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    172. Purification and kinetic characterization of the mitogen-activated protein kinase phosphatase rVH6. J Biol Chem. 1996 Dec 27; 271(52):33486-92. Wiland AM, Denu JM, Mourey RJ, Dixon JE. PMID: 8969212.
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    174. Form and function in protein dephosphorylation. Cell. 1996 Nov 01; 87(3):361-4. Denu JM, Stuckey JA, Saper MA, Dixon JE. PMID: 8898189.
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    175. Glial cell line-derived neurotrophic factor activates the receptor tyrosine kinase RET and promotes kidney morphogenesis. Proc Natl Acad Sci U S A. 1996 Oct 01; 93(20):10657-61. Vega QC, Worby CA, Lechner MS, Dixon JE, Dressler GR. PMID: 8855235; PMCID: PMC38210.
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    176. Role of the Kv4.3 K+ channel in ventricular muscle. A molecular correlate for the transient outward current. Circ Res. 1996 Oct; 79(4):659-68. Dixon JE, Shi W, Wang HS, McDonald C, Yu H, Wymore RS, Cohen IS, McKinnon D. PMID: 8831489.
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    177. Glial cell line-derived neurotrophic factor signals through the RET receptor and activates mitogen-activated protein kinase. J Biol Chem. 1996 Sep 27; 271(39):23619-22. Worby CA, Vega QC, Zhao Y, Chao HH, Seasholtz AF, Dixon JE. PMID: 8798576.
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    178. A Drosophila protein-tyrosine phosphatase associates with an adapter protein required for axonal guidance. J Biol Chem. 1996 Jul 19; 271(29):17002-5. Clemens JC, Ursuliak Z, Clemens KK, Price JV, Dixon JE. PMID: 8663600.
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    179. The SH2 domain-containing tyrosine phosphatase PTP1D is required for interferon alpha/beta-induced gene expression. J Biol Chem. 1996 Jul 05; 271(27):15862-5. David M, Zhou G, Pine R, Dixon JE, Larner AC. PMID: 8663536.
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    180. Transition-state structures for the native dual-specific phosphatase VHR and D92N and S131A mutants. Contributions to the driving force for catalysis. Biochemistry. 1996 Jun 04; 35(22):7084-92. Hengge AC, Denu JM, Dixon JE. PMID: 8679534.
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    181. Crystal structure of the dual specificity protein phosphatase VHR. Science. 1996 May 31; 272(5266):1328-31. Yuvaniyama J, Denu JM, Dixon JE, Saper MA. PMID: 8650541.
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    182. Direct association between the Ret receptor tyrosine kinase and the Src homology 2-containing adapter protein Grb7. J Biol Chem. 1996 May 03; 271(18):10607-10. Pandey A, Liu X, Dixon JE, Di Fiore PP, Dixit VM. PMID: 8631863.
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    183. Visualization of intermediate and transition-state structures in protein-tyrosine phosphatase catalysis. Proc Natl Acad Sci U S A. 1996 Mar 19; 93(6):2493-8. Denu JM, Lohse DL, Vijayalakshmi J, Saper MA, Dixon JE. PMID: 8637902; PMCID: PMC39825.
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    184. Oncogenic RET receptors display different autophosphorylation sites and substrate binding specificities. J Biol Chem. 1996 Mar 08; 271(10):5309-12. Liu X, Vega QC, Decker RA, Pandey A, Worby CA, Dixon JE. PMID: 8621380.
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    185. Parathyroid hormone regulates the expression of the receptor protein tyrosine phosphatase, OST-PTP, in rat osteoblast-like cells. Endocrinology. 1996 Mar; 137(3):925-33. Mauro LJ, Olmsted EA, Davis AR, Dixon JE. PMID: 8603605.
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    186. A novel cytoplasmic dual specificity protein tyrosine phosphatase implicated in muscle and neuronal differentiation. J Biol Chem. 1996 Feb 16; 271(7):3795-802. Mourey RJ, Vega QC, Campbell JS, Wenderoth MP, Hauschka SD, Krebs EG, Dixon JE. PMID: 8631996.
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    187. Selective activation of MEK1 but not MEK2 by A-Raf from epidermal growth factor-stimulated Hela cells. J Biol Chem. 1996 Feb 09; 271(6):3265-71. Wu X, Noh SJ, Zhou G, Dixon JE, Guan KL. PMID: 8621729.
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    189. Potassium channel mRNA expression in prevertebral and paravertebral sympathetic neurons. Eur J Neurosci. 1996 Jan; 8(1):183-91. Dixon JE, McKinnon D. PMID: 8713462.
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    192. hVH-5: a protein tyrosine phosphatase abundant in brain that inactivates mitogen-activated protein kinase. J Neurochem. 1995 Oct; 65(4):1823-33. Martell KJ, Seasholtz AF, Kwak SP, Clemens KK, Dixon JE. PMID: 7561881.
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    206. Mutational analysis of a Ser/Thr phosphatase. Identification of residues important in phosphoesterase substrate binding and catalysis. J Biol Chem. 1994 Oct 21; 269(42):26234-8. Zhuo S, Clemens JC, Stone RL, Dixon JE. PMID: 7929339.
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    207. Resolution of immobile chi structures by the FLP recombinase of 2 microns plasmid. J Mol Biol. 1994 Oct 21; 243(2):199-207. Dixon JE, Sadowski PD. PMID: 7932750.
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    208. Crystal structure of Yersinia protein tyrosine phosphatase at 2.5 A and the complex with tungstate. Nature. 1994 Aug 18; 370(6490):571-5. Stuckey JA, Schubert HL, Fauman EB, Zhang ZY, Dixon JE, Saper MA. PMID: 8052312.
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    209. Chromosomal localization of four human VH1-like protein-tyrosine phosphatases. Genomics. 1994 Jul 15; 22(2):462-4. Martell KJ, Kwak S, Hakes DJ, Dixon JE, Trent JM. PMID: 7806236.
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    210. 'Zip codes' direct intracellular protein tyrosine phosphatases to the correct cellular 'address'. Trends Biochem Sci. 1994 Apr; 19(4):151-5. Mauro LJ, Dixon JE. PMID: 8016862.
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    211. Nature of the rate-determining steps of the reaction catalyzed by the Yersinia protein-tyrosine phosphatase. J Biol Chem. 1994 Mar 18; 269(11):8140-5. Zhang ZY, Malachowski WP, Van Etten RL, Dixon JE. PMID: 8132539.
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    212. Dissecting the catalytic mechanism of protein-tyrosine phosphatases. Proc Natl Acad Sci U S A. 1994 Mar 01; 91(5):1624-7. Zhang ZY, Wang Y, Dixon JE. PMID: 8127855; PMCID: PMC43215.
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    213. Protein tyrosine phosphatase substrate specificity: size and phosphotyrosine positioning requirements in peptide substrates. Biochemistry. 1994 Mar 01; 33(8):2285-90. Zhang ZY, Maclean D, McNamara DJ, Sawyer TK, Dixon JE. PMID: 7509638.
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    214. Two genes for de novo purine nucleotide synthesis on human chromosome 4 are closely linked and divergently transcribed. J Biol Chem. 1994 Feb 18; 269(7):5313-21. Brayton KA, Chen Z, Zhou G, Nagy PL, Gavalas A, Trent JM, Deaven LL, Dixon JE, Zalkin H. PMID: 8106516.
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    215. Isolation and characterization of a human dual specificity protein-tyrosine phosphatase gene. J Biol Chem. 1994 Feb 04; 269(5):3596-604. Kwak SP, Hakes DJ, Martell KJ, Dixon JE. PMID: 8106404.
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    216. Protein tyrosine phosphatases: characterization of extracellular and intracellular domains. Curr Opin Genet Dev. 1994 Feb; 4(1):31-9. Mourey RJ, Dixon JE. PMID: 8193537.
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    217. Protein tyrosine phosphatases: mechanism of catalysis and substrate specificity. Adv Enzymol Relat Areas Mol Biol. 1994; 68:1-36. Zhang ZY, Dixon JE. PMID: 8154323.
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    218. Resolution of synthetic chi structures by the FLP site-specific recombinase. J Mol Biol. 1993 Dec 05; 234(3):522-33. Dixon JE, Sadowski PD. PMID: 8254657.
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    219. Bacterial and viral protein tyrosine phosphatases. Semin Cell Biol. 1993 Dec; 4(6):389-96. Guan KL, Dixon JE. PMID: 8305677.
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    220. Purification and characterization of the candidate prohormone-processing enzyme SPC3 produced in a mouse L cell line. J Biol Chem. 1993 Sep 25; 268(27):20291-8. Rufaut NW, Brennan SO, Hakes DJ, Dixon JE, Birch NP. PMID: 8376387.
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    221. Expression, purification, and kinetic characterization of recombinant human adenylosuccinate lyase. J Biol Chem. 1993 Sep 15; 268(26):19710-6. Stone RL, Zalkin H, Dixon JE. PMID: 8366112.
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    222. Active site labeling of the Yersinia protein tyrosine phosphatase: the determination of the pKa of the active site cysteine and the function of the conserved histidine 402. Biochemistry. 1993 Sep 14; 32(36):9340-5. Zhang ZY, Dixon JE. PMID: 8369304.
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    223. Expression, purification, crystallization, and biochemical characterization of a recombinant protein phosphatase. J Biol Chem. 1993 Aug 25; 268(24):17754-61. Zhuo S, Clemens JC, Hakes DJ, Barford D, Dixon JE. PMID: 8394350.
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    224. Expression, purification, and characterization of CTP:glycerol-3-phosphate cytidylyltransferase from Bacillus subtilis. J Biol Chem. 1993 Aug 05; 268(22):16648-54. Park YS, Sweitzer TD, Dixon JE, Kent C. PMID: 8393871.
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    225. A novel receptor-type protein tyrosine phosphatase is expressed during neurogenesis in the olfactory neuroepithelium. Neuron. 1993 Aug; 11(2):387-400. Walton KM, Martell KJ, Kwak SP, Dixon JE, Largent BL. PMID: 8352946.
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    226. Tissue-specific and substrate-specific endoproteolytic cleavage of monkey pro-opiomelanocortin in heterologous endocrine cells: processing at Lys-Lys dibasic pairs. Neuroendocrinology. 1993 Jul; 58(1):94-105. Lin HL, Day NC, Ueda Y, Martin DK, Dixon JE, Seidah NG, Akil H. PMID: 7903430.
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    227. Substrate specificity of the protein tyrosine phosphatases. Proc Natl Acad Sci U S A. 1993 May 15; 90(10):4446-50. Zhang ZY, Thieme-Sefler AM, Maclean D, McNamara DJ, Dobrusin EM, Sawyer TK, Dixon JE. PMID: 7685104; PMCID: PMC46528.
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    228. A continuous spectrophotometric and fluorimetric assay for protein tyrosine phosphatase using phosphotyrosine-containing peptides. Anal Biochem. 1993 May 15; 211(1):7-15. Zhang ZY, Maclean D, Thieme-Sefler AM, Roeske RW, Dixon JE. PMID: 7686722.
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    229. A protein phosphatase related to the vaccinia virus VH1 is encoded in the genomes of several orthopoxviruses and a baculovirus. Proc Natl Acad Sci U S A. 1993 May 01; 90(9):4017-21. Hakes DJ, Martell KJ, Zhao WG, Massung RF, Esposito JJ, Dixon JE. PMID: 8387208; PMCID: PMC46437.
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    230. Alternative splicing gives rise to a nuclear protein tyrosine phosphatase in Drosophila. J Biol Chem. 1993 Apr 05; 268(10):6839-42. McLaughlin S, Dixon JE. PMID: 8463208.
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    231. In vitro activation of the transcription factor ISGF3 by interferon alpha involves a membrane-associated tyrosine phosphatase and tyrosine kinase. J Biol Chem. 1993 Mar 25; 268(9):6593-9. David M, Romero G, Zhang ZY, Dixon JE, Larner AC. PMID: 8454630.
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    232. Binding constant determination studies utilizing recombinant delta CREB protein. DNA Cell Biol. 1993 Mar; 12(2):183-90. Williams JS, Dixon JE, Andrisani OM. PMID: 8471166.
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    233. Mutations of the FLP recombinase gene that cause a deficiency in DNA bending and strand cleavage. J Biol Chem. 1993 Jan 15; 268(2):1101-8. Kulpa J, Dixon JE, Pan G, Sadowski PD. PMID: 8419317.
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    234. The yeast open reading frame encoding a dual specificity phosphatase. Trends Biochem Sci. 1993 Jan; 18(1):6. Guan K, Hakes D, Dixon JE, Park HD, Cooper TG. PMID: 8438236.
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    235. Protein tyrosine phosphatases. Annu Rev Biochem. 1993; 62:101-20. Walton KM, Dixon JE. PMID: 8352585.
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    236. A yeast protein phosphatase related to the vaccinia virus VH1 phosphatase is induced by nitrogen starvation. Proc Natl Acad Sci U S A. 1992 Dec 15; 89(24):12175-9. Guan K, Hakes DJ, Wang Y, Park HD, Cooper TG, Dixon JE. PMID: 1334559; PMCID: PMC50721.
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    237. The Yersinia tyrosine phosphatase: specificity of a bacterial virulence determinant for phosphoproteins in the J774A.1 macrophage. J Exp Med. 1992 Dec 01; 176(6):1625-30. Bliska JB, Clemens JC, Dixon JE, Falkow S. PMID: 1281213; PMCID: PMC2119465.
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    238. Negative regulation of mitosis by two functionally overlapping PTPases in fission yeast. EMBO J. 1992 Dec; 11(13):4943-52. Millar JB, Russell P, Dixon JE, Guan KL. PMID: 1464319; PMCID: PMC556972.
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    239. Expression, purification, and physicochemical characterization of a recombinant Yersinia protein tyrosine phosphatase. J Biol Chem. 1992 Nov 25; 267(33):23759-66. Zhang ZY, Clemens JC, Schubert HL, Stuckey JA, Fischer MW, Hume DM, Saper MA, Dixon JE. PMID: 1429715.
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    240. cAMP-dependent protein kinase, but not the cGMP-dependent enzyme, rapidly phosphorylates delta-CREB, and a synthetic delta-CREB peptide. Biochem Cell Biol. 1992 Oct-Nov; 70(10-11):1277-82. Colbran JL, Roach PJ, Fiol CJ, Dixon JE, Andrisani OM, Corbin JD. PMID: 1338414.
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    241. Expression, purification, and characterization of the functional dimeric cytoplasmic domain of human erythrocyte band 3 in Escherichia coli. Protein Sci. 1992 Sep; 1(9):1206-14. Wang CC, Badylak JA, Lux SE, Moriyama R, Dixon JE, Low PS. PMID: 1304397; PMCID: PMC2142179.
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    242. A thousand and two protein tyrosine phosphatases. Biochim Biophys Acta. 1992 Jul 22; 1136(1):35-43. Pot DA, Dixon JE. PMID: 1643113.
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    243. Cloning and characterization of the cDNA encoding human adenylosuccinate synthetase. FEBS Lett. 1992 May 25; 303(1):4-10. Powell SM, Zalkin H, Dixon JE. PMID: 1592113.
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    244. Isolation and characterization of a second protein tyrosine phosphatase gene, PTP2, from Saccharomyces cerevisiae. J Biol Chem. 1992 May 15; 267(14):10024-30. Guan K, Deschenes RJ, Dixon JE. PMID: 1577774.
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    245. New vectors for high level expression of recombinant proteins in bacteria. Anal Biochem. 1992 May 01; 202(2):293-8. Hakes DJ, Dixon JE. PMID: 1519755.
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    246. Conserved histidine residues in soybean lipoxygenase: functional consequences of their replacement. Biochemistry. 1992 Apr 28; 31(16):4053-7. Steczko J, Donoho GP, Clemens JC, Dixon JE, Axelrod B. PMID: 1567851.
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    247. Avian glutamine phosphoribosylpyrophosphate amidotransferase propeptide processing and activity are dependent upon essential cysteine residues. J Biol Chem. 1992 Apr 15; 267(11):7936-42. Zhou G, Broyles SS, Dixon JE, Zalkin H. PMID: 1560022.
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    248. Expression of a protein tyrosine phosphatase in normal and v-src-transformed mouse 3T3 fibroblasts. J Cell Biol. 1992 Apr; 117(2):401-14. Woodford-Thomas TA, Rhodes JD, Dixon JE. PMID: 1373143; PMCID: PMC2289417.
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    249. A mutation in adenylosuccinate lyase associated with mental retardation and autistic features. Nat Genet. 1992 Apr; 1(1):59-63. Stone RL, Aimi J, Barshop BA, Jaeken J, Van den Berghe G, Zalkin H, Dixon JE. PMID: 1302001.
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    250. Active site labeling of a receptor-like protein tyrosine phosphatase. J Biol Chem. 1992 Jan 05; 267(1):140-3. Pot DA, Dixon JE. PMID: 1730581.
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    251. Isolation of two complementary deoxyribonucleic acid clones from a rat insulinoma cell line based on similarities to Kex2 and furin sequences and the specific localization of each transcript to endocrine and neuroendocrine tissues in rats. Endocrinology. 1991 Dec; 129(6):3053-63. Hakes DJ, Birch NP, Mezey A, Dixon JE. PMID: 1954888.
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    252. Involvement of lysine residues 289 and 291 of the cAMP-responsive element-binding protein in the recognition of the cAMP-responsive element. J Biol Chem. 1991 Nov 15; 266(32):21444-50. Andrisani OM, Dixon JE. PMID: 1834659.
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    253. Microbial pathogenesis and tyrosine dephosphorylation: surprising 'bedfellows'. Mol Microbiol. 1991 Nov; 5(11):2617-20. Clemens JC, Guan K, Bliska JB, Falkow S, Dixon JE. PMID: 1723471.
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    254. Cloning, bacterial expression, purification, and characterization of the cytoplasmic domain of rat LAR, a receptor-like protein tyrosine phosphatase. J Biol Chem. 1991 Oct 15; 266(29):19688-96. Pot DA, Woodford TA, Remboutsika E, Haun RS, Dixon JE. PMID: 1918076.
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    255. De novo purine nucleotide biosynthesis: cloning, sequencing and expression of a chicken PurH cDNA encoding 5-aminoimidazole-4-carboxamide-ribonucleotide transformylase-IMP cyclohydrolase. Gene. 1991 Oct 15; 106(2):197-205. Ni L, Guan K, Zalkin H, Dixon JE. PMID: 1937050.
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    257. Structural characterization of the rat carboxypeptidase-E gene. Mol Endocrinol. 1991 Sep; 5(9):1257-68. Jung YK, Kunczt CJ, Pearson RK, Dixon JE, Fricker LD. PMID: 1770952.
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    258. Characterization of the carboxyl-terminal sequences responsible for protein retention in the endoplasmic reticulum. J Biol Chem. 1991 Aug 05; 266(22):14277-82. Andres DA, Rhodes JD, Meisel RL, Dixon JE. PMID: 1650354.
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    259. Cloning and expression of a yeast protein tyrosine phosphatase. J Biol Chem. 1991 Jul 15; 266(20):12964-70. Guan KL, Deschenes RJ, Qiu H, Dixon JE. PMID: 1649172.
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    260. Effect of ethanol and low-temperature culture on expression of soybean lipoxygenase L-1 in Escherichia coli. Protein Expr Purif. 1991 Apr-Jun; 2(2-3):221-7. Steczko J, Donoho GA, Dixon JE, Sugimoto T, Axelrod B. PMID: 1821792.
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    261. A Tyr/Ser protein phosphatase encoded by vaccinia virus. Nature. 1991 Mar 28; 350(6316):359-62. Guan KL, Broyles SS, Dixon JE. PMID: 1848923.
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    263. Eukaryotic proteins expressed in Escherichia coli: an improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase. Anal Biochem. 1991 Feb 01; 192(2):262-7. Guan KL, Dixon JE. PMID: 1852137.
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    264. Cloning and expression of avian glutamine phosphoribosylpyrophosphate amidotransferase. Conservation of a bacterial propeptide sequence supports a role for posttranslational processing. J Biol Chem. 1990 Dec 05; 265(34):21152-9. Zhou GC, Dixon JE, Zalkin H. PMID: 2123487.
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    265. De novo purine nucleotide biosynthesis: cloning of human and avian cDNAs encoding the trifunctional glycinamide ribonucleotide synthetase-aminoimidazole ribonucleotide synthetase-glycinamide ribonucleotide transformylase by functional complementation in E. coli. Nucleic Acids Res. 1990 Nov 25; 18(22):6665-72. Aimi J, Qiu H, Williams J, Zalkin H, Dixon JE. PMID: 2147474; PMCID: PMC332626.
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    266. A transcriptional enhancer essential for the expression of the rat cholecystokinin gene contains a sequence identical to the -296 element of the human c-fos gene. J Biol Chem. 1990 Sep 15; 265(26):15455-63. Haun RS, Dixon JE. PMID: 2118525.
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    267. Efforts directed at understanding cell-specific somatostatin gene expression. Metabolism. 1990 Sep; 39(9 Suppl 2):17-9. Dixon JE, Zhu A, Andrisani O. PMID: 1976211.
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    269. Cloning of a cDNA encoding adenylosuccinate lyase by functional complementation in Escherichia coli. J Biol Chem. 1990 Jun 05; 265(16):9011-4. Aimi J, Badylak J, Williams J, Chen ZD, Zalkin H, Dixon JE. PMID: 2111814.
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    271. Cloning of a chicken liver cDNA encoding 5-aminoimidazole ribonucleotide carboxylase and 5-aminoimidazole-4-N-succinocarboxamide ribonucleotide synthetase by functional complementation of Escherichia coli pur mutants. Proc Natl Acad Sci U S A. 1990 Apr; 87(8):3097-101. Chen ZD, Dixon JE, Zalkin H. PMID: 1691501; PMCID: PMC53841.
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    272. Cloning and structural characterization of porcine heart aconitase. J Biol Chem. 1990 Feb 15; 265(5):2814-21. Zheng L, Andrews PC, Hermodson MA, Dixon JE, Zalkin H. PMID: 2303429.
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    273. Biosynthesis and posttranslational processing of site-directed endoproteolytic cleavage mutants of pro-neuropeptide Y in mouse pituitary cells. J Biol Chem. 1990 Feb 15; 265(5):2462-9. Dickerson IM, Dixon JE, Mains RE. PMID: 2303410.
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    295. Purification and separation of pyridine nucleotide-linked dehydrogenases by affinity chromatography techniques. Proc Natl Acad Sci U S A. 1974 Sep; 71(9):3450-4. Kaplan NO, Everse J, Dixon JE, Stolzenbach FE, Lee CY, Lee CL, Taylor SS, Mosbach K. PMID: 4372619; PMCID: PMC433791.
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    296. Production of glass bead-immobilized catecholamines. Methods Enzymol. 1974; 38:180-6. Venter JC, Dixon JE. PMID: 4453191.
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    297. Comparison of the rate constants for general base catalyzed prototropy and racemization of the aldimine species formed from 3-hydroxypyridine-4-carboxaldehyde and alanine. Biochemistry. 1973 Nov 06; 12(23):4762-6. Dixon JE, Bruice TC. PMID: 4773854.
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    298. An apparatus for the determination of kinetic parameters associated with immobilized enzymes. Anal Biochem. 1973 Sep; 55(1):282-7. Widmer F, Dixon JE, Kaplan NO. PMID: 4753153.
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    299. Immobilized catecholamine and cocaine effects on contractility of cardiac muscle. Proc Natl Acad Sci U S A. 1973 Apr; 70(4):1214-7. Venter JC, Ross J, Dixon JE, Mayer SE, Kaplan NO. PMID: 4515619; PMCID: PMC433460.
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    300. Biologically active catecholamines covalentyly bound to glass beads. Proc Natl Acad Sci U S A. 1972 May; 69(5):1141-5. Venter JC, Dixon JE, Maroko PR, Kaplan NO. PMID: 4338583; PMCID: PMC426649.
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