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    Xin Zhou

    TitleAssistant Project Scientist
    SchoolUniversity of California, San Diego
    Address9500 Gilman Drive #0702
    CA La Jolla 92093
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      Collapse Biography 
      Collapse Education and Training
      Johns Hopkins University2015Pharmacology/School of Medicine
      University of MinnesotaPhD2010Medicinal Chemistry/School of Pharmacy
      Beijing Sport UniversityM.S.2004Exercise Biochemistry
      Peking University B.S.2001Pharmaceutical Chemistry/School of Pharmacy

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      Collapse Featured Publications

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Shah R, Maize KM, Zhou X, Finzel BC, Wagner CR. Caught before Released: Structural Mapping of the Reaction Trajectory for the Sofosbuvir Activating Enzyme, Human Histidine Triad Nucleotide Binding Protein 1 (hHint1). Biochemistry. 2017 Jul 18; 56(28):3559-3570. PMID: 28691797.
        View in: PubMed
      2. Zhou X, Li S, Zhang J. Tracking the Activity of mTORC1 in Living Cells Using Genetically Encoded FRET-based Biosensor TORCAR. Curr Protoc Chem Biol. 2016 Dec 07; 8(4):225-233. PMID: 27925667.
        View in: PubMed
      3. Zhang Z, Mu Y, Veevers J, Peter AK, Manso AM, Bradford WH, Dalton ND, Peterson KL, Knowlton KU, Ross RS, Zhou X, Chen J. Postnatal Loss of Kindlin-2 Leads to Progressive Heart Failure. Circ Heart Fail. 2016 Aug; 9(8). PMID: 27502369; PMCID: PMC4979611 [Available on 08/01/17].
      4. Karlsson I, Zhou X, Thomas R, Smith AT, Bonner MY, Bakshi P, Banga AK, Bowen JP, Qabaja G, Ford SL, Ballard MD, Petersen KS, Li X, Chen G, Ogretmen B, Zhang J, Watkins EB, Arnold RS, Arbiser JL. Solenopsin A and analogs exhibit ceramide-like biological activity. Vasc Cell. 2015; 7:5. PMID: 26015865; PMCID: PMC4443652.
      5. Zhou X, Clister TL, Lowry PR, Seldin MM, Wong GW, Zhang J. Dynamic Visualization of mTORC1 Activity in Living Cells. Cell Rep. 2015 Mar 11. PMID: 25772363.
        View in: PubMed
      6. Zhou X, Chou TF, Aubol BE, Park CJ, Wolfenden R, Adams J, Wagner CR. Kinetic mechanism of human histidine triad nucleotide binding protein 1. Biochemistry. 2013 May 21; 52(20):3588-600. PMID: 23614568; PMCID: PMC3835729.
      7. Zhou X, Herbst-Robinson KJ, Zhang J. Visualizing dynamic activities of signaling enzymes using genetically encodable FRET-based biosensors from designs to applications. Methods Enzymol. 2012; 504:317-40. PMID: 22264542; PMCID: PMC4384881.
      8. Gao X, Lowry PR, Zhou X, Depry C, Wei Z, Wong GW, Zhang J. PI3K/Akt signaling requires spatial compartmentalization in plasma membrane microdomains. Proc Natl Acad Sci U S A. 2011 Aug 30; 108(35):14509-14. PMID: 21873248; PMCID: PMC3167518.
      9. Zhou X, Zhang N, Liu L, Walters KJ, Hanna PE, Wagner CR. Probing the catalytic potential of the hamster arylamine N-acetyltransferase 2 catalytic triad by site-directed mutagenesis of the proximal conserved residue, Tyr190. FEBS J. 2009 Dec; 276(23):6928-41. PMID: 19860825; PMCID: PMC2805756.
      10. Cheng J, Zhou X, Chou TF, Ghosh B, Liu B, Wagner CR. Identification of the amino acid-AZT-phosphoramidase by affinity T7 phage display selection. Bioorg Med Chem Lett. 2009 Nov 15; 19(22):6379-81. PMID: 19825512.
        View in: PubMed
      11. Chou TF, Baraniak J, Kaczmarek R, Zhou X, Cheng J, Ghosh B, Wagner CR. Phosphoramidate pronucleotides: a comparison of the phosphoramidase substrate specificity of human and Escherichia coli histidine triad nucleotide binding proteins. Mol Pharm. 2007 Mar-Apr; 4(2):208-17. PMID: 17217311.
        View in: PubMed
      12. Liu F, Zhang N, Zhou X, Hanna PE, Wagner CR, Koepp DM, Walters KJ. Arylamine N-acetyltransferase aggregation and constitutive ubiquitylation. J Mol Biol. 2006 Aug 18; 361(3):482-92. PMID: 16857211.
        View in: PubMed