Sign in to edit your profile (add interests, mentoring, photo, etc.)

    Weg Ongkeko

    TitleAssociate Adjunct Professor
    SchoolUniversity of California, San Diego
    DepartmentSurgery
    Address9500 Gilman Drive #9151
    CA La Jolla 92093
    Phone858-552-8585
    vCardDownload vCard

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Yu V, Singh P, Rahimy E, Zheng H, Kuo SZ, Kim E, Wang-Rodriguez J, Ongkeko WM. RNA-seq analysis identifies key long non-coding RNAs connected to the pathogenesis of alcohol-associated head and neck squamous cell carcinoma. Oncol Lett. 2016 Oct; 12(4):2846-2853. PMID: 27698869.
        View in: PubMed
      2. Hwang JH, Lyes M, Sladewski K, Enany S, McEachern E, Mathew DP, Das S, Moshensky A, Bapat S, Pride DT, Ongkeko WM, Crotty Alexander LE. Electronic cigarette inhalation alters innate immunity and airway cytokines while increasing the virulence of colonizing bacteria. J Mol Med (Berl). 2016 Jun; 94(6):667-79. PMID: 26804311.
        View in: PubMed
      3. Yu V, Rahimy M, Korrapati A, Xuan Y, Zou AE, Krishnan AR, Tsui T, Aguilera JA, Advani S, Crotty Alexander LE, Brumund KT, Wang-Rodriguez J, Ongkeko WM. Electronic cigarettes induce DNA strand breaks and cell death independently of nicotine in cell lines. Oral Oncol. 2016 Jan; 52:58-65. PMID: 26547127.
        View in: PubMed
      4. Saad MA, Kuo SZ, Rahimy E, Zou AE, Korrapati A, Rahimy M, Kim E, Zheng H, Yu MA, Wang-Rodriguez J, Ongkeko WM. Alcohol-dysregulated miR-30a and miR-934 in head and neck squamous cell carcinoma. Mol Cancer. 2015; 14(1):181. PMID: 26472042.
        View in: PubMed
      5. Zou AE, Ku J, Honda TK, Yu V, Kuo SZ, Zheng H, Xuan Y, Saad MA, Hinton A, Brumund KT, Lin JH, Wang-Rodriguez J, Ongkeko WM. Transcriptome sequencing uncovers novel long noncoding and small nucleolar RNAs dysregulated in head and neck squamous cell carcinoma. RNA. 2015 Jun; 21(6):1122-34. PMID: 25904139.
        View in: PubMed
      6. Ongkeko WM, Burton D, Kiang A, Abhold E, Kuo SZ, Rahimy E, Yang M, Hoffman RM, Wang-Rodriguez J, Deftos LJ. Parathyroid Hormone Related-Protein Promotes Epithelial-to-Mesenchymal Transition in Prostate Cancer. PLoS One. 2014 Jan 22; 9(1):e85803. PMID: 24465715.
        View in: PubMed
      7. Rahimy E, Kuo SZ, Ongkeko WM. Evaluation of Non-Coding RNAs as Potential Targets in Head and Neck Squamous Cell Carcinoma Cancer Stem Cells. Curr Drug Targets. 2014; 15(13):1247-60. PMID: 25341422.
        View in: PubMed
      8. Yu MA, Kiang A, Wang-Rodriguez J, Rahimy E, Haas M, Yu V, Ellies LG, Chen J, Fan JB, Brumund KT, Weisman RA, Ongkeko WM. Nicotine promotes acquisition of stem cell and epithelial-to-mesenchymal properties in head and neck squamous cell carcinoma. PLoS One. 2012; 7(12):e51967. PMID: 23300583.
        View in: PubMed
      9. Yi D, Kuo SZ, Zheng H, Abhold EL, Brown CM, Doherty JK, Wang-Rodriguez J, Harris JP, Ongkeko WM. Activation of PDGFR and EGFR promotes the acquisition of a stem cell-like phenotype in schwannomas. Otol Neurotol. 2012 Dec; 33(9):1640-7. PMID: 22935817.
        View in: PubMed
      10. Kuo SZ, Blair KJ, Rahimy E, Kiang A, Abhold E, Fan JB, Wang-Rodriguez J, Altuna X, Ongkeko WM. Salinomycin induces cell death and differentiation in head and neck squamous cell carcinoma stem cells despite activation of epithelial-mesenchymal transition and Akt. BMC Cancer. 2012; 12:556. PMID: 23176396.
        View in: PubMed
      11. An Y, Kiang A, Lopez JP, Kuo SZ, Yu MA, Abhold EL, Chen JS, Wang-Rodriguez J, Ongkeko WM. Cigarette smoke promotes drug resistance and expansion of cancer stem cell-like side population. PLoS One. 2012; 7(11):e47919. PMID: 23144836.
        View in: PubMed
      12. Abhold EL, Kiang A, Rahimy E, Kuo SZ, Wang-Rodriguez J, Lopez JP, Blair KJ, Yu MA, Haas M, Brumund KT, Altuna X, Patel A, Weisman RA, Ongkeko WM. EGFR kinase promotes acquisition of stem cell-like properties: a potential therapeutic target in head and neck squamous cell carcinoma stem cells. PLoS One. 2012; 7(2):e32459. PMID: 22384257.
        View in: PubMed
      13. Kiang A, Yu MA, Ongkeko WM. Progress and pitfalls in the identification of cancer stem cell-targeting therapies in head and neck squamous cell carcinoma. Curr Med Chem. 2012; 19(35):6056-64. PMID: 22963569.
        View in: PubMed
      14. Abhold E, Rahimy E, Wang-Rodriguez J, Blair KJ, Yu MA, Brumund KT, Weisman RA, Ongkeko WM. Recombinant human erythropoietin promotes the acquisition of a malignant phenotype in head and neck squamous cell carcinoma cell lines in vitro. BMC Res Notes. 2011; 4:553. PMID: 22188703.
        View in: PubMed
      15. Altuna X, Algaba J, Ongkeko W. Expression of p63 and p73 in acoustic neuroma and its possible clinical relevance. Acta Otorrinolaringol Esp. 2012 Jan-Feb; 63(1):9-14. PMID: 22000483.
        View in: PubMed
      16. Blair KJ, Kiang A, Wang-Rodriguez J, Yu MA, Doherty JK, Ongkeko WM. EGF and bFGF promote invasion that is modulated by PI3/Akt kinase and Erk in vestibular schwannoma. Otol Neurotol. 2011 Feb; 32(2):308-14. PMID: 21178801.
        View in: PubMed
      17. Altuna X, Lopez JP, Yu MA, Arandazi MJ, Harris JP, Wang-Rodriguez J, An Y, Dobrow R, Doherty JK, Ongkeko WM. Potential role of imatinib mesylate (Gleevec, STI-571) in the treatment of vestibular schwannoma. Otol Neurotol. 2011 Jan; 32(1):163-70. PMID: 21157293.
        View in: PubMed
      18. Tran Cao HS, Kaushal S, Snyder CS, Ongkeko WM, Hoffman RM, Bouvet M. Real-time imaging of tumor progression in a fluorescent orthotopic mouse model of thyroid cancer. Anticancer Res. 2010 Nov; 30(11):4415-22. PMID: 21115887.
        View in: PubMed
      19. Wang XQ, Ongkeko WM, Chen L, Yang ZF, Lu P, Chen KK, Lopez JP, Poon RT, Fan ST. Octamer 4 (Oct4) mediates chemotherapeutic drug resistance in liver cancer cells through a potential Oct4-AKT-ATP-binding cassette G2 pathway. Hepatology. 2010 Aug; 52(2):528-39. PMID: 20683952.
        View in: PubMed
      20. An Y, Ongkeko WM. ABCG2: the key to chemoresistance in cancer stem cells? Expert Opin Drug Metab Toxicol. 2009 Dec; 5(12):1529-42. PMID: 19708828.
        View in: PubMed
      21. Ahmad ZK, Altuna X, Lopez JP, An Y, Wang-Rodriguez J, Juneja VR, Chen JS, Arandazi MJ, Aguilera J, Harris JP, Ongkeko WM. p73 expression and function in vestibular schwannoma. Arch Otolaryngol Head Neck Surg. 2009 Jul; 135(7):662-9. PMID: 19620587.
        View in: PubMed
      22. Chu TS, Chen JS, Lopez JP, Pardo FS, Aguilera J, Ongkeko WM. Imatinib-mediated inactivation of Akt regulates ABCG2 function in head and neck squamous cell carcinoma. Arch Otolaryngol Head Neck Surg. 2008 Sep; 134(9):979-84. PMID: 18794444.
        View in: PubMed
      23. Lopez JP, Wang-Rodriguez J, Chang CY, Sneh G, Yu MA, Pardo FS, Aguilera J, Ongkeko WM. Gefitinib (Iressa) potentiates the effect of ionizing radiation in thyroid cancer cell lines. Laryngoscope. 2008 Aug; 118(8):1372-6. PMID: 18475209.
        View in: PubMed
      24. Doherty JK, Ongkeko W, Crawley B, Andalibi A, Ryan AF. ErbB and Nrg: potential molecular targets for vestibular schwannoma pharmacotherapy. Otol Neurotol. 2008 Jan; 29(1):50-7. PMID: 18199957.
        View in: PubMed
      25. Lopez JP, Wang-Rodriguez J, Chang C, Chen JS, Pardo FS, Aguilera J, Ongkeko WM. Gefitinib inhibition of drug resistance to doxorubicin by inactivating ABCG2 in thyroid cancer cell lines. Arch Otolaryngol Head Neck Surg. 2007 Oct; 133(10):1022-7. PMID: 17938326.
        View in: PubMed
      26. Pham TT, Ongkeko WM, An Y, Yi ES. Protein expression of the tumor suppressors p16INK4A and p53 and disease progression in recurrent respiratory papillomatosis. Laryngoscope. 2007 Feb; 117(2):253-7. PMID: 17277618.
        View in: PubMed
      27. Ongkeko WM, An Y, Chu TS, Aguilera J, Dang CL, Wang-Rodriguez J. Gleevec suppresses p63 expression in head and neck squamous cell carcinoma despite p63 activation by DNA-damaging agents. Laryngoscope. 2006 Aug; 116(8):1390-6. PMID: 16885742.
        View in: PubMed
      28. Wang-Rodriguez J, Lopez JP, Altuna X, Chu TS, Weisman RA, Ongkeko WM. STI-571 (Gleevec) potentiates the effect of cisplatin in inhibiting the proliferation of head and neck squamous cell carcinoma in vitro. Laryngoscope. 2006 Aug; 116(8):1409-16. PMID: 16885745.
        View in: PubMed
      29. Chen JS, Pardo FS, Wang-Rodriguez J, Chu TS, Lopez JP, Aguilera J, Altuna X, Weisman RA, Ongkeko WM. EGFR regulates the side population in head and neck squamous cell carcinoma. Laryngoscope. 2006 Mar; 116(3):401-6. PMID: 16540898.
        View in: PubMed
      30. Ongkeko WM, Altuna X, Weisman RA, Wang-Rodriguez J. Expression of protein tyrosine kinases in head and neck squamous cell carcinomas. Am J Clin Pathol. 2005 Jul; 124(1):71-6. PMID: 15923166.
        View in: PubMed
      31. Altuna Mariezkurrena X, Algaba Guimerá J, Wang Rodríguez J, Weisman R, Ongkeko W. [Immunohistochemistry study of EGFR expression in head and neck squamous cell carcinoma]. Acta Otorrinolaringol Esp. 2005 Apr; 56(4):143-6. PMID: 15871288.
        View in: PubMed
      32. Wang XQ, Ongkeko WM, Lau AW, Leung KM, Poon RY. A possible role of p73 on the modulation of p53 level through MDM2. Cancer Res. 2001 Feb 15; 61(4):1598-603. PMID: 11245471.
        View in: PubMed
      33. Ongkeko WM, Wang XQ, Siu WY, Lau AW, Yamashita K, Harris AL, Cox LS, Poon RY. MDM2 and MDMX bind and stabilize the p53-related protein p73. Curr Biol. 1999 Jul 29-Aug 12; 9(15):829-32. PMID: 10469568.
        View in: PubMed
      34. Winters ZE, Ongkeko WM, Harris AL, Norbury CJ. p53 regulates Cdc2 independently of inhibitory phosphorylation to reinforce radiation-induced G2 arrest in human cells. Oncogene. 1998 Aug 13; 17(6):673-84. PMID: 9715268.
        View in: PubMed
      35. Sandri MI, Isaacs RJ, Ongkeko WM, Harris AL, Hickson ID, Broggini M, Vikhanskaya F. p53 regulates the minimal promoter of the human topoisomerase IIalpha gene. Nucleic Acids Res. 1996 Nov 15; 24(22):4464-70. PMID: 8948636.
        View in: PubMed
      36. Ongkeko W, Ferguson DJ, Harris AL, Norbury C. Inactivation of Cdc2 increases the level of apoptosis induced by DNA damage. J Cell Sci. 1995 Aug; 108 ( Pt 8):2897-904. PMID: 7593329.
        View in: PubMed
      Back to TOP