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    Scott Thomson

    TitleProfessor In Residence
    SchoolUniversity of California, San Diego
    DepartmentMedicine
    Address9500 Gilman Drive #9151
    CA La Jolla 92093
    Phone858-552-7528
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      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Vallon V, Thomson S. Targeting renal glucose reabsorption to treat hyperglycaemia: the pleiotropic effects of SGLT2 inhibition. Diabetologia. 2016 Nov 22. PMID: 27878313.
        View in: PubMed
      2. Singh P, Thomson S. Salt sensitivity of tubuloglomerular feedback in the early remnant kidney. Am J Physiol Renal Physiol. 2014 Jan; 306(2):F172-80. PMID: 24259514.
        View in: PubMed
      3. Rieg T, Masuda T, Gerasimova M, Mayoux E, Platt K, Powell DR, Thomson S, Koepsell H, Vallon V. Increase in SGLT1-mediated transport explains renal glucose reabsorption during genetic and pharmacological SGLT2 inhibition in euglycemia. Am J Physiol Renal Physiol. 2014 Jan; 306(2):F188-93. PMID: 24226519.
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      4. Vallon V, Gerasimova M, Rose MA, Masuda T, Satriano J, Mayoux E, Koepsell H, Thomson S, Rieg T. SGLT2 inhibitor empagliflozin reduces renal growth and albuminuria in proportion to hyperglycemia and prevents glomerular hyperfiltration in diabetic Akita mice. Am J Physiol Renal Physiol. 2014 Jan; 306(2):F194-204. PMID: 24226524.
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      5. Vallon V, Rose M, Gerasimova M, Satriano J, Platt KA, Koepsell H, Cunard R, Sharma K, Thomson S, Rieg T. Knockout of Na-glucose transporter SGLT2 attenuates hyperglycemia and glomerular hyperfiltration but not kidney growth or injury in diabetes mellitus. Am J Physiol Renal Physiol. 2013 Jan 15; 304(2):F156-67. PMID: 23152292.
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      6. Thomson S, Kashkouli A, Singh P. Glucagon-like peptide-1 receptor stimulation increases GFR and suppresses proximal reabsorption in the rat. Am J Physiol Renal Physiol. 2013 Jan 15; 304(2):F137-44. PMID: 23019232.
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      7. Thomson S, Blantz RC. Biophysics of glomerular filtration. Compr Physiol. 2012 Jul; 2(3):1671-99. PMID: 23723020.
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      8. Bell HJ, Syed NI. Control of breathing in invertebrate model systems. Compr Physiol. 2012 Jul; 2(3):1745-66. PMID: 23723022.
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      9. Blantz RC, Singh P, Deng A, Thomson S, Vallon V. Acute saline expansion increases nephron filtration and distal flow rate but maintains tubuloglomerular feedback responsiveness: role of adenosine A(1) receptors. Am J Physiol Renal Physiol. 2012 Aug 1; 303(3):F405-11. PMID: 22622464.
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      10. Teerlink JR, Iragui VJ, Mohr JP, Carson PE, Hauptman PJ, Lovett DH, Miller AB, PiƱa IL, Thomson S, Varosy PD, Zile MR, Cleland JG, Givertz MM, Metra M, Ponikowski P, Voors AA, Davison BA, Cotter G, Wolko D, Delucca P, Salerno CM, Mansoor GA, Dittrich H, O'Connor CM, Massie BM. The safety of an adenosine A(1)-receptor antagonist, rolofylline, in patients with acute heart failure and renal impairment: findings from PROTECT. Drug Saf. 2012 Mar 1; 35(3):233-44. PMID: 22339573.
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      11. Singh P, Blantz RC, Rosenberger C, Gabbai FB, Schoeb TR, Thomson S. Aberrant tubuloglomerular feedback and HIF-1a confer resistance to ischemia after subtotal nephrectomy. J Am Soc Nephrol. 2012 Mar; 23(3):483-93. PMID: 22266667.
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      12. Vallon V, Thomson S. Renal function in diabetic disease models: the tubular system in the pathophysiology of the diabetic kidney. Annu Rev Physiol. 2012; 74:351-75. PMID: 22335797.
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      13. Thomson S, Rieg T, Miracle C, Mansoury H, Whaley J, Vallon V, Singh P. Acute and chronic effects of SGLT2 blockade on glomerular and tubular function in the early diabetic rat. Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1; 302(1):R75-83. PMID: 21940401.
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      14. Vallon V, Thomson S. Anomalous role for dietary salt in diabetes mellitus? Nat Rev Endocrinol. 2011 Jul; 7(7):377-8. PMID: 21629234.
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      15. Thomson S, Blantz RC. A new role for charge of the glomerular capillary membrane. J Am Soc Nephrol. 2010 Dec; 21(12):2011-3. PMID: 21051741.
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      16. Deng A, Arndt MA, Satriano J, Singh P, Rieg T, Thomson S, Tang T, Blantz RC. Renal protection in chronic kidney disease: hypoxia-inducible factor activation vs. angiotensin II blockade. Am J Physiol Renal Physiol. 2010 Dec; 299(6):F1365-73. PMID: 20881034.
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      17. Vallon V, Platt KA, Cunard R, Schroth J, Whaley J, Thomson S, Koepsell H, Rieg T. SGLT2 mediates glucose reabsorption in the early proximal tubule. J Am Soc Nephrol. 2011 Jan; 22(1):104-12. PMID: 20616166.
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      18. Satriano J, Mansoury H, Deng A, Sharma K, Vallon V, Blantz RC, Thomson S. Transition of kidney tubule cells to a senescent phenotype in early experimental diabetes. Am J Physiol Cell Physiol. 2010 Aug; 299(2):C374-80. PMID: 20505038.
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      19. Singh P, Thomson S. Renal homeostasis and tubuloglomerular feedback. Curr Opin Nephrol Hypertens. 2010 Jan; 19(1):59-64. PMID: 19864948.
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      20. Deng A, Thomson S. Renal NMDA receptors independently stimulate proximal reabsorption and glomerular filtration. Am J Physiol Renal Physiol. 2009 May; 296(5):F976-82. PMID: 19279130.
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      21. Vallon V, Schroth J, Satriano J, Blantz RC, Thomson S, Rieg T. Adenosine A(1) receptors determine glomerular hyperfiltration and the salt paradox in early streptozotocin diabetes mellitus. Nephron Physiol. 2009; 111(3):p30-8. PMID: 19276628.
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      22. Singh P, Deng A, Blantz RC, Thomson S. Unexpected effect of angiotensin AT1 receptor blockade on tubuloglomerular feedback in early subtotal nephrectomy. Am J Physiol Renal Physiol. 2009 May; 296(5):F1158-65. PMID: 19211684.
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      23. Deng A, Tang T, Singh P, Wang C, Satriano J, Thomson S, Blantz RC. Regulation of oxygen utilization by angiotensin II in chronic kidney disease. Kidney Int. 2009 Jan; 75(2):197-204. PMID: 18818681.
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      24. Miracle CM, Rieg T, Mansoury H, Vallon V, Thomson S. Ornithine decarboxylase inhibitor eliminates hyperresponsiveness of the early diabetic proximal tubule to dietary salt. Am J Physiol Renal Physiol. 2008 Oct; 295(4):F995-F1002. PMID: 18562630.
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      25. Ruiz M, Singh P, Thomson S, Munger K, Blantz RC, Gabbai FB. L-arginine-induced glomerular hyperfiltration response: the roles of insulin and ANG II. Am J Physiol Regul Integr Comp Physiol. 2008 May; 294(5):R1744-51. PMID: 18353876.
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      26. Thomson S, Blantz RC. Glomerulotubular balance, tubuloglomerular feedback, and salt homeostasis. J Am Soc Nephrol. 2008 Dec; 19(12):2272-5. PMID: 18322161.
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      27. Vallon V, Miracle C, Thomson S. Adenosine and kidney function: potential implications in patients with heart failure. Eur J Heart Fail. 2008 Feb; 10(2):176-87. PMID: 18242127.
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      28. Miracle CM, Rieg T, Blantz RC, Vallon V, Thomson S. Combined effects of carbonic anhydrase inhibitor and adenosine A1 receptor antagonist on hemodynamic and tubular function in the kidney. Kidney Blood Press Res. 2007; 30(6):388-99. PMID: 17890869.
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      29. Blantz RC, Deng A, Miracle CM, Thomson S. Regulation of kidney function and metabolism: a question of supply and demand. Trans Am Clin Climatol Assoc. 2007; 118:23-43. PMID: 18528487.
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      30. Satriano J, Wead L, Cardus A, Deng A, Boss GR, Thomson S, Blantz RC. Regulation of ecto-5'-nucleotidase by NaCl and nitric oxide: potential roles in tubuloglomerular feedback and adaptation. Am J Physiol Renal Physiol. 2006 Nov; 291(5):F1078-82. PMID: 16705150.
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      31. Thomson S, Deng A, Wead L, Richter K, Blantz RC, Vallon V. An unexpected role for angiotensin II in the link between dietary salt and proximal reabsorption. J Clin Invest. 2006 Apr; 116(4):1110-6. PMID: 16557296.
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      32. Deng A, Miracle CM, Lortie M, Satriano J, Gabbai FB, Munger KA, Thomson S, Blantz RC. Kidney oxygen consumption, carbonic anhydrase, and proton secretion. Am J Physiol Renal Physiol. 2006 May; 290(5):F1009-15. PMID: 16352743.
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      33. Deng A, Miracle CM, Suarez JM, Lortie M, Satriano J, Thomson S, Munger KA, Blantz RC. Oxygen consumption in the kidney: effects of nitric oxide synthase isoforms and angiotensin II. Kidney Int. 2005 Aug; 68(2):723-30. PMID: 16014049.
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      34. Vallon V, Blantz R, Thomson S. The salt paradox and its possible implications in managing hypertensive diabetic patients. Curr Hypertens Rep. 2005 Apr; 7(2):141-7. PMID: 15748540.
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      35. Lortie MJ, Satriano J, Gabbai FB, Thareau S, Khang S, Deng A, Pizzo DP, Thomson S, Blantz RC, Munger KA. Production of arginine by the kidney is impaired in a model of sepsis: early events following LPS. Am J Physiol Regul Integr Comp Physiol. 2004 Dec; 287(6):R1434-40. PMID: 15308488.
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      36. Slomowitz LA, Gabbai FB, Khang SJ, Satriano J, Thareau S, Deng A, Thomson S, Blantz RC, Munger KA. Protein intake regulates the vasodilatory function of the kidney and NMDA receptor expression. Am J Physiol Regul Integr Comp Physiol. 2004 Nov; 287(5):R1184-9. PMID: 15242825.
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      37. Thomson S, Deng A, Komine N, Hammes JS, Blantz RC, Gabbai FB. Early diabetes as a model for testing the regulation of juxtaglomerular NOS I. Am J Physiol Renal Physiol. 2004 Oct; 287(4):F732-8. PMID: 15213066.
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      38. Thomson S, Vallon V, Blantz RC. Kidney function in early diabetes: the tubular hypothesis of glomerular filtration. Am J Physiol Renal Physiol. 2004 Jan; 286(1):F8-15. PMID: 14656757.
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      39. Thomson S. Commentary on...neuronal nitric oxide synthase: its role and regulation in macula densa cells. J Am Soc Nephrol. 2003 Oct; 14(10):2688-9. PMID: 14514751.
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      40. Deng A, Munger KA, Valdivielso JM, Satriano J, Lortie M, Blantz RC, Thomson S. Increased expression of ornithine decarboxylase in distal tubules of early diabetic rat kidneys: are polyamines paracrine hypertrophic factors? Diabetes. 2003 May; 52(5):1235-9. PMID: 12716758.
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      41. Vallon V, Blantz RC, Thomson S. Glomerular hyperfiltration and the salt paradox in early [corrected] type 1 diabetes mellitus: a tubulo-centric view. J Am Soc Nephrol. 2003 Feb; 14(2):530-7. PMID: 12538755.
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      42. Thomson S, Deng A. Cyclic GMP mediates influence of macula densa nitric oxide over tubuloglomerular feedback. Kidney Blood Press Res. 2003; 26(1):10-8. PMID: 12697972.
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      43. Deng A, Hammes JS, Thomson S. Hemodynamics of early tubuloglomerular feedback resetting during reduced proximal reabsorption. Kidney Int. 2002 Dec; 62(6):2136-43. PMID: 12427138.
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      44. Vallon V, Huang DY, Deng A, Richter K, Blantz RC, Thomson S. Salt-sensitivity of proximal reabsorption alters macula densa salt and explains the paradoxical effect of dietary salt on glomerular filtration rate in diabetes mellitus. J Am Soc Nephrol. 2002 Jul; 13(7):1865-71. PMID: 12089382.
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      45. Deng A, Valdivielso JM, Munger KA, Blantz RC, Thomson S. Vasodilatory N-methyl-D-aspartate receptors are constitutively expressed in rat kidney. J Am Soc Nephrol. 2002 May; 13(5):1381-4. PMID: 11961027.
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      46. Slomowitz LA, Deng A, Hammes JS, Gabbai F, Thomson S. Glomerulotubular balance, dietary protein, and the renal response to glycine in diabetic rats. Am J Physiol Regul Integr Comp Physiol. 2002 Apr; 282(4):R1096-103. PMID: 11893614.
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      47. Blantz RC, Deng A, Lortie M, Munger K, Vallon V, Gabbai FB, Thomson S. The complex role of nitric oxide in the regulation of glomerular ultrafiltration. Kidney Int. 2002 Mar; 61(3):782-5. PMID: 11849425.
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      48. Gabbai FB, Hammond TC, Thomson S, Khang S, Kelly CJ. Effect of acute iNOS inhibition on glomerular function in tubulointerstitial nephritis. Kidney Int. 2002 Mar; 61(3):851-4. PMID: 11849437.
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      49. Thomson S. Adenosine and purinergic mediators of tubuloglomerular feedback. Curr Opin Nephrol Hypertens. 2002 Jan; 11(1):81-6. PMID: 11753091.
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      50. Thomson S, Deng A, Bao D, Satriano J, Blantz RC, Vallon V. Ornithine decarboxylase, kidney size, and the tubular hypothesis of glomerular hyperfiltration in experimental diabetes. J Clin Invest. 2001 Jan; 107(2):217-24. PMID: 11160138.
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      51. Thomson S, Bao D, Deng A, Vallon V. Adenosine formed by 5'-nucleotidase mediates tubuloglomerular feedback. J Clin Invest. 2000 Jul; 106(2):289-98. PMID: 10903345.
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      52. Thomson S, Bachmann S, Bostanjoglo M, Ecelbarger CA, Peterson OW, Schwartz D, Bao D, Blantz RC. Temporal adjustment of the juxtaglomerular apparatus during sustained inhibition of proximal reabsorption. J Clin Invest. 1999 Oct; 104(8):1149-58. PMID: 10525054.
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      53. Thomson S, Vallon V, Blantz RC. Resetting protects efficiency of tubuloglomerular feedback. Kidney Int Suppl. 1998 Sep; 67:S65-70. PMID: 9736256.
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