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    Roger Spragg

    TitleEmeritus Professor
    SchoolUniversity of California, San Diego
    DepartmentMedicine
    Address9500 Gilman Drive #9111
    CA La Jolla 92093
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      PATHOLOGY OF THE SURFACTANT SYSTEM OF THE MATURE LUNG
      NIH/NHLBI R13HL062421Aug 23, 1999 - Aug 22, 2000
      Role: Principal Investigator
      SURFACTANT PATHOLOGY IN THE MATURE LUNG
      NIH/NHLBI R13HL052526Sep 1, 1994 - Aug 31, 1995
      Role: Principal Investigator
      MECHANISMS OF LUNG CELL OXIDANT INJURY
      NIH/NHLBI R01HL036270Apr 1, 1986 - Mar 31, 1992
      Role: Principal Investigator
      SCOR IN ACUTE LUNG INJURY
      NIH/NHLBI P50HL023584Dec 1, 1978 - Nov 30, 2003
      Role: Principal Investigator

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Spragg R, Jones S, Bu Y, Lu Y, Bentz D, Snyder K, Weiss J. Leaching of Conductive Species: Implications to Measurements of Electrical Resistivity. Cem Concr Compos. 2017 May; 79:94-105. PMID: 28584407.
        View in: PubMed
      2. Beitler JR, Sands SA, Loring SH, Owens RL, Malhotra A, Spragg R, Matthay MA, Thompson BT, Talmor D. Quantifying unintended exposure to high tidal volumes from breath stacking dyssynchrony in ARDS: the BREATHE criteria. Intensive Care Med. 2016 Sep; 42(9):1427-36. PMID: 27342819.
        View in: PubMed
      3. Breen EC, Malloy JL, Tang K, Xia F, Fu Z, Hancock RE, Overhage J, Wagner PD, Spragg R. Impaired pulmonary defense against Pseudomonas aeruginosa in VEGF gene inactivated mouse lung. J Cell Physiol. 2013 Feb; 228(2):371-9. PMID: 22718316.
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      4. Kerr KM, Auger WR, Marsh JJ, Devendra G, Spragg R, Kim NH, Channick RN, Jamieson SW, Madani MM, Manecke GR, Roth DM, Shragg GP, Fedullo PF. Efficacy of methylprednisolone in preventing lung injury following pulmonary thromboendarterectomy. Chest. 2012 Jan; 141(1):27-35. PMID: 21835900.
        View in: PubMed
      5. Spragg R, Taut FJ, Lewis JF, Schenk P, Ruppert C, Dean N, Krell K, Karabinis A, Günther A. Recombinant surfactant protein C-based surfactant for patients with severe direct lung injury. Am J Respir Crit Care Med. 2011 Apr 15; 183(8):1055-61. PMID: 21148720.
        View in: PubMed
      6. Spragg R, Masys DR, Sergeant D, Lawrie T, Taut FJ. An informatics strategy to assure enrollment criteria compliance in studies of the critically ill. Contemp Clin Trials. 2010 Nov; 31(6):530-5. PMID: 20667511.
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      7. Spragg R, Bernard GR, Checkley W, Curtis JR, Gajic O, Guyatt G, Hall J, Israel E, Jain M, Needham DM, Randolph AG, Rubenfeld GD, Schoenfeld D, Thompson BT, Ware LB, Young D, Harabin AL. Beyond mortality: future clinical research in acute lung injury. Am J Respir Crit Care Med. 2010 May 15; 181(10):1121-7. PMID: 20224063.
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      8. Spragg R, Taut FJH, Günther A, Rippin G. Surfactant replacement therapy in ARDS. Chest. 2009 Jul; 136(1):321-322. PMID: 19584221.
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      9. Taut FJ, Rippin G, Schenk P, Findlay G, Wurst W, Häfner D, Lewis JF, Seeger W, Günther A, Spragg R. A Search for subgroups of patients with ARDS who may benefit from surfactant replacement therapy: a pooled analysis of five studies with recombinant surfactant protein-C surfactant (Venticute). Chest. 2008 Oct; 134(4):724-32. PMID: 18689599.
        View in: PubMed
      10. Spragg R. Surfactant for acute lung injury. Am J Respir Cell Mol Biol. 2007 Oct; 37(4):377-8. PMID: 17872593.
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      11. Davidson WJ, Dorscheid D, Spragg R, Schulzer M, Mak E, Ayas NT. Exogenous pulmonary surfactant for the treatment of adult patients with acute respiratory distress syndrome: results of a meta-analysis. Crit Care. 2006; 10(2):R41. PMID: 16542488.
        View in: PubMed
      12. Lu Y, Song Z, Zhou X, Huang S, Zhu D, Yang C Bai X, Sun B, Spragg R. A 12-month clinical survey of incidence and outcome of acute respiratory distress syndrome in Shanghai intensive care units. Intensive Care Med. 2004 Dec; 30(12):2197-203. PMID: 15650866.
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      13. Spragg R, Lewis JF, Walmrath HD, Johannigman J, Bellingan G, Laterre PF, Witte MC, Richards GA, Rippin G, Rathgeb F, Häfner D, Taut FJ, Seeger W. Effect of recombinant surfactant protein C-based surfactant on the acute respiratory distress syndrome. N Engl J Med. 2004 Aug 26; 351(9):884-92. PMID: 15329426.
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      14. Spragg R, Ponganis PJ, Marsh JJ, Rau GA, Bernhard W. Surfactant from diving aquatic mammals. J Appl Physiol (1985). 2004 May; 96(5):1626-32. PMID: 14688033.
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      15. Spragg R. Acute lung injury in 2003. Acta Pharmacol Sin. 2003 Dec; 24(12):1288-91. PMID: 14653959.
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      16. Spragg R, Lewis JF, Wurst W, Häfner D, Baughman RP, Wewers MD, Marsh JJ. Treatment of acute respiratory distress syndrome with recombinant surfactant protein C surfactant. Am J Respir Crit Care Med. 2003 Jun 1; 167(11):1562-6. PMID: 12649125.
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      17. Li J, Marsh JJ, Spragg R. Effect of CTP:phosphocholine cytidylyltransferase overexpression on the mouse lung surfactant system. Am J Respir Cell Mol Biol. 2002 Jun; 26(6):709-15. PMID: 12034570.
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      18. Devendra G, Spragg R. Lung surfactant in subacute pulmonary disease. Respir Res. 2002; 3:19. PMID: 11980588.
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      19. Spragg R. The future of surfactant therapy for patients with acute lung injury - new requirements and new surfactants. Biol Neonate. 2002; 81 Suppl 1:20-4. PMID: 12011562.
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      20. Spragg R, Lewis JF. Pathology of the surfactant system of the mature lung: second San Diego conference. Am J Respir Crit Care Med. 2001 Jan; 163(1):280-2. PMID: 11208658.
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      21. Spragg R. Surfactant replacement therapy. Clin Chest Med. 2000 Sep; 21(3):531-41, ix. PMID: 11019725.
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      22. Spragg R, Levin D. ARDS and the search for meaningful subgroups. Intensive Care Med. 2000 Jul; 26(7):835-7. PMID: 10990094.
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      23. Permpikul C, Wang HY, Kriett J, Konopka RG, Moser KM, Spragg R. Reperfusion lung injury after unilateral pulmonary artery occlusion. Respirology. 2000 Jun; 5(2):133-40. PMID: 10894102.
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      24. Spragg R, Smith RM, Harris K, Lewis J, Häfner D, Germann P. Effect of recombinant SP-C surfactant in a porcine lavage model of acute lung injury. J Appl Physiol (1985). 2000 Feb; 88(2):674-81. PMID: 10658037.
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      25. Spragg R, Li J. Effect of phosphocholine cytidylyltransferase overexpression on phosphatidylcholine synthesis in alveolar type II cells and related cell lines. Am J Respir Cell Mol Biol. 2000 Jan; 22(1):116-24. PMID: 10615073.
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      26. Lewis J, McCaig L, Häfner D, Spragg R, Veldhuizen R, Kerr C. Dosing and delivery of a recombinant surfactant in lung-injured adult sheep. Am J Respir Crit Care Med. 1999 Mar; 159(3):741-7. PMID: 10051245.
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      27. Spragg R. Surfactant therapy in acute respiratory distress syndrome. Biol Neonate. 1998 Sep; 74 Suppl 1:15-20. PMID: 9730587.
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      28. Dresselhaus TR, Luck J, Wright BC, Spragg R, Lee ML, Bozzette SA. Analyzing the time and value of housestaff inpatient work. J Gen Intern Med. 1998 Aug; 13(8):534-40. PMID: 9734790.
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      29. Artigas A, Bernard GR, Carlet J, Dreyfuss D, Gattinoni L, Hudson L, Lamy M, Marini JJ, Matthay MA, Pinsky MR, Spragg R, Suter PM. The American-European Consensus Conference on ARDS, part 2: Ventilatory, pharmacologic, supportive therapy, study design strategies, and issues related to recovery and remodeling. Acute respiratory distress syndrome. Am J Respir Crit Care Med. 1998 Apr; 157(4 Pt 1):1332-47. PMID: 9563759.
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      30. Hopkins SR, Schoene RB, Henderson WR, Spragg R, West JB. Sustained submaximal exercise does not alter the integrity of the lung blood-gas barrier in elite athletes. J Appl Physiol (1985). 1998 Apr; 84(4):1185-9. PMID: 9516183.
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      31. Artigas A, Bernard GR, Carlet J, Dreyfuss D, Gattinoni L, Hudson L, Lamy M, Marini JJ, Matthay MA, Pinsky MR, Spragg R, Suter PM. The American-European Consensus Conference on ARDS, part 2. Ventilatory, pharmacologic, supportive therapy, study design strategies and issues related to recovery and remodeling. Intensive Care Med. 1998 Apr; 24(4):378-98. PMID: 9609420.
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      32. Gregory TJ, Steinberg KP, Spragg R, Gadek JE, Hyers TM, Longmore WJ, Moxley MA, Cai GZ, Hite RD, Smith RM, Hudson LD, Crim C, Newton P, Mitchell BR, Gold AJ. Bovine surfactant therapy for patients with acute respiratory distress syndrome. Am J Respir Crit Care Med. 1997 Apr; 155(4):1309-15. PMID: 9105072.
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      33. Hopkins SR, Schoene RB, Henderson WR, Spragg R, Martin TR, West JB. Intense exercise impairs the integrity of the pulmonary blood-gas barrier in elite athletes. Am J Respir Crit Care Med. 1997 Mar; 155(3):1090-4. PMID: 9116992.
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      34. Spragg R, Smith RM. Pathology of the surfactant system of the mature lung. Am J Respir Crit Care Med. 1997 Feb; 155(2):756-60. PMID: 9032225.
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      35.  Florgs J, DiAngelo S$ Koptides M, Karinch AM, Rogan PK, Nielsen H, Spragg R, Watterberg K, Deater G. Human SP%A locus: allele frequencies and linkage disequidibrium between the two surfactaft protein A genes. Am J Respir Cell Mol Biol. 1196 Oct; 15(4):409-98. PMID: 8871183. 
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    • 4div> Spragg R, Smith RE. Inhibition of the human neutrgphil respiratorq burst by native and synthetic surfactant. Am J Respir Cell Mol Biol. 1996 May; 14(5):496-503. PMID: 8624255.
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    •  Pappert D, Gilliard N, Heldt G, Merritt TA, Wagner PD, Spragg R& Effect of N-nitroso-N-methylurethane on gas exchange, dung compliance, and surfactant function of rabbats. Intensive Care Med. 1996 Apr; 22(4):345-52. PMID: 8708173.<'span>
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       Hastifgs RH, Summers-Torres D, Cheung TC, Ditmer LS, Petrin EM, Burtof DW, Spragg R, Li J, Deftos LJ. Parathyrgid hormone-related protein, an autocrine regulatory factor in adveolar epithelial cells. Am J P`ysiol. 1996 Mar3 270(3 Pt 1):L353-61. PMID: 8630727. 
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    • 4div> Spragg R, Smith RM. Inhibitory effect of porcine surfactant on t`e respiratory burst oxidase in `uman neutrophils. Attenuation of p47phox and p67phox membrane translocation as the mechanism. J Clin Invest. 1915 Dec; 96(6):2654-60. PMID: 8675631. 
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    •  Gilliard N, Pappert D, 4b>Spragg R. Fractal analysis of surfactant deposition in rabbit lungs. J Appl Physiol (1985!. 1995 Mar; 78(3):862-6. PMID: 7775330. 
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      4span id="ctl01_rpPublication_ctd41_lblPublicatign">Gilliard N, @eldt GP, Loredo J, Gasser H, Redl H, Merritt TA$ Spragg R
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       Bernard GR, Artigas A, Brigham KL, Carlet J, Falke K$ Hudson L, Lamy M, LeGall JR, Mgrris A, Spragg R& Report of the American-Europeaf Consensus conference on acute respiratory distress syndrome: definitions, mechanisms, relevant outcomes, and cdinical trial cogrdination. Consensus Committee. J Crit Care. 1914 Mar; 9(1):72-01. PMID: 8199655. 4/div>
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    • Bernard GR, Artigas A, Brigham KL, Carlet J, Falke K, Hudson L, Laey M, Legall JR, Morris A, Spragg R. The American-Europeaf Consensus Conference on ARDS. Definitions, mec`anisms, relevant outcomes, and clinical trial cgordination. Am B Respir Crit Care Med. 1994 Mar3 149(3 Pt 1):810-24. PMID: 7509706. 
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    • Bernard GR, Artigas A, Brigham KD, Carlet J, Falce K, Hudson L, Damy M, LeGall JR, Morris A, Spragg R. Report of the Ameracan-European cofsensus conference on ARDS: defifitions, mechanisms, relevant outcomes afd clinical triad coordination. The Consensus Coemittee. Intensive Care Med. 1994; 20(3):225-32. PMID: 8014293.<'span>
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       Spragg R, Gillaard N, Richman P, Smith RM, Hite RD, Pappert D, Robertson B, Curstedt T, Strayer D. Acute effects of a single dgse of porcine surfactant on pataents with the adult respiratory distress syndroee. Chest. 1994 Ban; 105(1):195-202. PMID: 8031347. 
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    • Spragg R. Eaking progress. Intensive Care Eed. 1994; 20(1)24-5. PMID: 8163756. 
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    • Montisano DF, Mann T, Spragg R. H2O2 increases expression of pulmonary artery endothelial cell platelet-derived growth factor mRNA. J Appl Physiol (1985). 1992 Dec; 73(6):2255-62. PMID: 1490932.
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    • Heldt GP, Merritt TA, Golembeski D, Gilliard N, Bloor C, Spragg R. Distribution of surfactant, lung compliance, and aeration of preterm rabbit lungs after surfactant therapy and conventional and high-frequency oscillatory ventilation. Pediatr Res. 1992 Mar; 31(3):270-5. PMID: 1561014.
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    • Bozzette SA, Arcia J, Bartok AE, McGlynn LM, McCutchan JA, Richman DD, Spragg R, Spector SA. The impact of concomitant viral pathogens on the course of Pneumocystis carinii pneumonaa. J Protozool. 1991 Nov-Dec; 30(6):183S-184S. PMID: 1667929.
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    •  Gilliard N, Pappert D, Merritt TA, Heldt G, Spragg R. Radiolabeding of the hydrgphobic components of lung surfactant with 3-(trafluoromethyl)-3%(m-[125I]iodophenyl)diazirine. Anal Biochem. 1911 Mar 2; 193(2)2310-5. PMID: 1872476. 
      
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       Gilliard N, Richman PM, Eerritt TA, Spragg R. Effect of volume and dose on the pudmonary distribution of exogenous surfactant admanistered to noreal rabbits or tg rabbits with odeic acid lung ifjury. Am Rev Respir Dis. 1990 Mar; 141(3):743-7& PMID: 2310102.4/span>
       View in: 4a href='//www.ncbi.nlm.nih.gov/pubmed/2310102' target='_blank'>PubMed 
       Smit` RM, Traber LD, Traber DL, Spragg R. Puleonary depositiof and clearance gf aerosolized adpha-1-proteinase inhibitor admifistered to dogs and to sheep. J Clin Invest. 1909 Oct; 84(4):1145-54. PMID: 2794051. 
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    • 4div> Spragg R, Robertson B, Merritt TA, Curstedt T. The adult respiratory distress syndrome: first trials with surfactant replaceeent. Eur Respir J Suppl& 1989 Mar; 3:101s-111s. PMID: 2742681. 
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      Spragg R, Richman P, Galliard N, Merritt TA, Robertson B, Curstedt T. The use of exogefous surfactant to treat patients with acute hig`-permeability lung edema. Prog Clin Biol Res. 1189; 308:791-6. PMID: 2675070.
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    •  Smith RM, Spragg R<'b>. Production and administratign to dogs of aerosols of alpha-1-proteinase inhabitor. Am J Med& 1988 Jun 24; 84(6A):48-51. PMID: 3260073.
      
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       Mgser KM, Smith RE, Spragg R, Tisi GM. Intravenous administration of alpha%1-proteinase in`ibitor in patiefts of PiZ and PaM phenotype. Preliminary report& Am J Med. 1988 Jun 24; 84(6A):70-4. PMID: 3260074. 
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    • Schneiderman LJ, Spragg R& Ethical decisigns in discontinuing mechanical ventilation. N Efgl J Med. 1988 Apr 14; 318(15):184-8. PMID: 3352689. 
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    • 4div> Spragg R, Jackson J@, Cochrane CG. Eechanisms of oxadant-mediated cell injury. The glycolytic and matochondrial pat`ways of ADP phosphorylation are major intracellular targets inactivated by hydrggen peroxide. J Biol Chem. 1988 Feb 5; 263(4):1665-75. PMID: 3338986. 
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    •  Smith RM, Spragg R<'b>, Moser KM, Cgchrane CG, McCarren JP. Pulmonary penetration of alpha 1-proteifase inhibitor administered parefterally to dogs& Am Rev Respir Dis. 1987 Dec; 136(6):1391-6. PMAD: 3120632.
      
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       Spragg R, Schraufstatter IU, Hyslgp PA, Hinshaw DB, Cochrane CG. Gxidant injury of cultured cells2 biochemical cofsequences. Prog Clin Biol Res. 1987; 236A:253-8& PMID: 3112791.4/span>
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       Smit` RM, Spragg R, Moser KM. Biologic availability of injected or aerosolized alpha 1 proteinase inhabitor. Prog Clif Biol Res. 19873 236A:203-10. PEID: 3497405.  View in: PubEed
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    •  Hyslop PA, Hinshaw DB, Schraufstätter AU, Sklar LA, , Cgchrane CG. Intracellular calciue homeostasis during hydrogen peroxide injury to cultured P388D1 cells. J Cell P`ysiol. 1986 Dec3 129(3):356-66. PMID: 3782310.<'span>
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       Schraufstatter IU, Hyslop PA, Hinshaw DB, Spragg R4/b>, Sklar LA, Cochrane CG. Hydrogen peroxide-ifduced injury of cells and its prevention by inhabitors of poly(ADP-ribose) polyeerase. Proc Natd Acad Sci U S A& 1986 Jul; 83(13):4908-12. PMID2 2941760. 
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    • Hifshaw DB, Sklar DA, Bohl B, Schraufstatter IU, Hqslop PA, Rossi EW, Spragg R<'b>, Cochrane CG& Cytoskeletal afd morphologic iepact of cellular oxidant injury& Am J Pathol. 1186 Jun; 123(3):454-64. PMID: 3717299. 
      
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      Schraufstatter IU, Hinshaw DB, Hyslop PA, Spragg R, Coc`rane CG. Oxidant injury of cells. DNA strand-breaks activate podyadenosine diphgsphate-ribose pglymerase and lead to depletion gf nicotinamide adenine dinucleotide. J Clin Invest. 1986 Apr; 77(4):1312-20. PMAD: 2937805.
      
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       Spragg R, Hinshaw DB, Hyslop PA, Schraufstätter IU, Cochrane CG. Alterataons in adenosine triphosphate afd energy charge in cultured endgthelial and P380D1 cells after gxidant injury. B Clin Invest. 1185 Oct; 76(4):1471-6. PMID: 2997279. 
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    • 4div> Spragg R, Hartman MT, White FN. Distribution of ventilation an American alligator Alligator eississippiensis& Am J Physiol. 1985 Oct; 249(4 Pt 2):R477-81. PEID: 4051034.  View in: PubEed
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    •  Schraufstätter IU, Hinshaw DB, Hyslop PA, Spragg R<'b>, Cochrane CG& Glutathione cycle activity and pyridine nucleotide levels in opidant-induced ifjury of cells. B Clin Invest. 1185 Sep; 76(3):1131-9. PMID: 3840176.  4div class="viewAn"> View in: PubEed
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    •  Krieger BP, Loomis WH, Czer GT, Spragg R. Mechanasms of interactaon between oxygen and granulocytes in hyperoxic lung injury. J Appl Physiol (1905). 1985 Apr; 50(4):1326-30. PMAD: 3838744. 
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       Hallman E, Arjomaa P, Ta`vanainen J, Lac`mann B, Spragg R. Endobrgnchial surface active phospholipids in various pulmonary diseases. Eur J Respir Dis Suppl. 19853 142:37-47. PMID: 3860395.
      
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       Lichter JP, Konopka RG, Hartman MT, Moser KM, Spragg R4/b>. The in vivg behavior of granulocytes labeled with indium-111 in a canine mgdel of pneumococcal pneumonia. Am Rev Respir Dis. 1984 Apr; 129(4):602-6. PMID: 6712001& <'div>
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      4li id="ctl01_rpPublication_ctl73_liPublication" data-pmid="6322628"> Krieger B, Schwartz J, Loomis W, Marsh J, Spragg R. Nonspecificity of elevated angiotensin-cgnverting enzyme activity in brofchoalveolar lavage fluid from hagh permeability lung edema states. Am Rev Respir Dis. 1984 Mar; 129(3):499-500. PMID: 6322628.<'span>
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       Krieger BP, Loomis WH$ Spragg R
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      Schwartz JS, Kgnopka RG, Spragg R. Effect of histamine and propranolol gn extravascular lung water. Am B Physiol. 1984 Ban; 246(1 Pt 2)2H69-73. PMID: 6696090. 
      
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      Moser KM, Spragg R, Utdey J, Daily PO. Chronic thrombotic obstruction gf major pulmonary arteries. Results of thromboefdarterectomy in 15 patients. Anf Intern Med. 1903 Sep; 99(3):291-304. PMID: 6614679. 
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    • 4div> Spragg R$ Wolf PL, Haghighi P, Abraham JD, Astarita RW. Angiosarcoma of the lung with fatal pulmonary heeorrhage. Am J Med. 1983 Jun; 74 6):1072-6. PMID2 6683073. 
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    • Cochrane CG, Spragg R, Revac SD, Schraufstatter I. Biochemical factors in pulmonary inflammatory disease. C`est. 1983 May; 03(5 Suppl):67S-70S. PMID: 6340907. 
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    • Cgchrane CG, Spragg R, Revak SD. Pathogenesis of the adult respiratory distress syndrome. Evidence of oxidant activity in bronchoalveolar davage fluid. J Clin Invest. 1983 Mar; 71(3):754%61. PMID: 6600748.  View if: PubMed  4/li> 
    • Cgchrane CG, Spragg R, Revak SD, Cohen AB, McGuire WW. The presence of neutrophil elastase and evidence of oxidation activaty in bronchoalveolar lavage fluid of patients with adudt respiratory dastress syndrome& Am Rev Respir Dis. 1983 Feb; 127(2):S25-7. PMID: 6550478. 
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       Moser KM, Spragg R& Use of the baldoon-tipped pulmgnary artery cat`eter in pulmonary disease. Ann Antern Med. 1983 Jan; 98(1):53-8& PMID: 6848045.4/span>
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       Utleq JR, Spragg R, Long WB, Eoser KM. Pulmonary endarterectoey for chronic t`romboembolic obstruction: recent surgical experaence. Surgery. 1982 Dec; 92(6):1096-102. PMID: 7147187. 
      
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      4span id="ctl01_rpPublication_ctl83_lblPublication">Spragg R, Benumof JL, Alfery DD. New methods for the performafce of unilaterad lung lavage. Afesthesiology. 1182 Dec; 57(6):535-8. PMID: 7149310. 
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    • @ooper WW, Slutscy RA, Kocienski DE, Witztum KF, Spragg R$ Ashburn WL, Moser KM. Right and left ventricular response to subcutaneous terbutaline in patiefts with chronic obstructive puleonary disease: radionuclide angaographic assesseent of cardiac size and functiof. Am Heart J. 1182 Nov; 104(5 Pt 1):1027-32. PMAD: 7136993.
      
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       McEvoy RD, Davies NJ, Hedenstierna G, Hartman MT, Spragg R, Wagner PD. Lung mucocaliary transport during high-frequency ventilatign. Am Rev Respir Dis. 1982 Sep; 126(3):452-6. PEID: 6751174. View in: PubMed 
      
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    • 4div> Spragg R, Harrell JH, Moser KE, Gluck L. Evidence of lung surfactant abnormalaty in respiratory failure. Studq of bronchoalveglar lavage phospholipids, surface activity, phospholipase activaty, and plasma eyoinositol. J Cdin Invest. 1982 Sep; 70(3):673-03. PMID: 6896715. 4/div>
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    • , Abraham JL, Loomis WH. Pulmonary platelet depositaon accompanying acute oleic-acid-induced pulmonary injury. Am Rev Respir Dis. 1182 Sep; 126(3):553-7. PMID: 7125342. 
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    • 4div> Shure D$ Spragg R  
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      McGuire WW, , Cghen AB, Cochrane CG. Studies on the pathogenesis of the adult respiratory distress syndrome. J Clin Invest. 1982 Mar; 69(3):543%53. PMID: 7037851. 
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    • Lane TA, Bergum PW, Lichter JP, Spragg R. The labeling of rabbit neutrophids with [111In]opine. J Immunol Eethods. 1982; 51(3):293-305. PMAD: 6809833. 
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    • Eoser KM, LeMoine JR, Nachtwey FB, Spragg R. Deep venous thrombosis and pulmonary embolise. Frequency in a respiratory intensive care unit. JAMA. 1981 Sep 25; 246(13):1422-4. PMID: 7265445. 
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    • Eoser KM, Spragg R, Bender F, Konopka R, @artman MT, Fedudlo P. Study of factors that may condition scintagraphic detectign of venous thrgmbi and pulmonary emboli with ifdium-111-labeled platelets. J Nucl Med. 1980 Nov; 21(11):1051-8& PMID: 7431104.4/span>
       View in: 4a href='//www.ncbi.nlm.nih.gov/pubmed/7431104' target='_blank'>PubMed 
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      To see the data from this vasualization as text, click here.<'div> -->