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    Robert Owens

    TitleAssociate Physician
    SchoolUniversity of California, San Diego
    Address9300 Campus Point Drive #7381
    CA La Jolla 92037
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      Collapse Research 
      Collapse Research Activities and Funding
      The Role of Lung Volumes in Nocturnal Asthma
      NIH/NHLBI K23HL105542Sep 15, 2011 - Jul 31, 2014
      Role: Principal Investigator
      The Role of Lung Volumes in Asthma
      NIH/NHLBI F32HL097578Aug 5, 2009 - Aug 4, 2011
      Role: Principal Investigator

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Li Y, Ye J, Han D, Cao X, Ding X, Zhang Y, Xu W, Orr J, Jen R, Sands S, Malhotra A, Owens R. Physiology-Based Modeling May Predict Surgical Treatment Outcome for Obstructive Sleep Apnea. J Clin Sleep Med. 2017 Sep 15; 13(9):1029-1037. PMID: 28818154.
        View in: PubMed
      2. Tainter CR, Nguyen AP, Pollock KA, O'Brien EO, Lee J, Schmidt U, Jahanasouz F, Owens R, Meier A. The impact of a daily "medication time out" in the Intensive Care Unit. J Crit Care. 2017 Sep 12. PMID: 28939276.
        View in: PubMed
      3. Owens R, Macrea MM, Teodorescu M. The overlaps of asthma or COPD with OSA: A focused review. Respirology. 2017 Aug; 22(6):1073-1083. PMID: 28677827.
        View in: PubMed
      4. Soler X, Liao SY, Marin JM, Lorenzi-Filho G, Jen R, DeYoung P, Owens R, Ries AL, Malhotra A. Age, gender, neck circumference, and Epworth sleepiness scale do not predict obstructive sleep apnea (OSA) in moderate to severe chronic obstructive pulmonary disease (COPD): The challenge to predict OSA in advanced COPD. PLoS One. 2017; 12(5):e0177289. PMID: 28510598.
        View in: PubMed
      5. Kang DY, DeYoung PN, Malhotra A, Owens R, Coleman TP. A State Space and Density Estimation Framework for Sleep Staging in Obstructive Sleep Apnea. IEEE Trans Biomed Eng. 2017 May 08. PMID: 28499990.
        View in: PubMed
      6. Jaiswal SJ, Owens R, Malhotra A. Raising awareness about sleep disorders. Lung India. 2017 May-Jun; 34(3):262-268. PMID: 28474653.
        View in: PubMed
      7. Luskin MR, Cronin AM, Owens R, DeAngelo DJ, Stone RM, Wadleigh M, Steensma DP, Abel GA. Self-reported sleep disturbance and survival in myelodysplastic syndromes. Br J Haematol. 2017 May; 177(4):562-566. PMID: 28272741.
        View in: PubMed
      8. Lamas DJ, Owens R, Nace RN, Massaro AF, Pertsch NJ, Moore ST, Bernacki RE, Block SD. Conversations About Goals and Values Are Feasible and Acceptable in Long-Term Acute Care Hospitals: A Pilot Study. J Palliat Med. 2017 Jul; 20(7):710-715. PMID: 28437209.
        View in: PubMed
      9. Owens R, Huynh TG, Netzer G. Sleep in the Intensive Care Unit in a Model of Family-Centered Care. AACN Adv Crit Care. 2017; 28(2):171-178. PMID: 28592477.
        View in: PubMed
      10. Laghi F, Owens R. COPD+OSA: can two bad things be good for you? Thorax. 2017 Mar; 72(3):204-205. PMID: 28011858.
        View in: PubMed
      11. Edwards BA, Andara C, Landry S, Sands SA, Joosten SA, Owens R, White DP, Hamilton GS, Wellman A. Upper-Airway Collapsibility and Loop Gain Predict the Response to Oral Appliance Therapy in Patients with Obstructive Sleep Apnea. Am J Respir Crit Care Med. 2016 Dec 01; 194(11):1413-1422. PMID: 27181367.
        View in: PubMed
      12. Owens R. Better Sleep in the Intensive Care Unit: Blue Pill or Red Pill… or No Pill? Anesthesiology. 2016 Nov; 125(5):835-837. PMID: 27571258.
        View in: PubMed
      13. Edwards BA, Sands SA, Owens R, Eckert DJ, Landry S, White DP, Malhotra A, Wellman A. The Combination of Supplemental Oxygen and a Hypnotic Markedly Improves Obstructive Sleep Apnea in Patients with a Mild to Moderate Upper Airway Collapsibility. Sleep. 2016 Nov 01; 39(11):1973-1983. PMID: 27634790.
        View in: PubMed
      14. Li Y, Owens R, Sands S, Orr J, Moraes W, DeYoung P, Smales E, Jen R, Malhotra A. The Effect of Donepezil on Arousal Threshold and Apnea-Hypopnea Index. A Randomized, Double-Blind, Cross-Over Study. Ann Am Thorac Soc. 2016 Nov; 13(11):2012-2018. PMID: 27442715.
        View in: PubMed
      15. Lamas DJ, Owens R, Nace RN, Massaro AF, Pertsch NJ, Gass J, Bernacki RE, Block SD. Opening the Door: The Experience of Chronic Critical Illness in a Long-Term Acute Care Hospital. Crit Care Med. 2016 Sep 14. PMID: 27632675.
        View in: PubMed
      16. Owens R, Gold KA, Gozal D, Peppard PE, Jun JC, Lippman SM, Malhotra A. Sleep and Breathing … and Cancer? Cancer Prev Res (Phila). 2016 Nov; 9(11):821-827. PMID: 27604751.
        View in: PubMed
      17. Jaiswal SJ, Malhotra A, Owens R. Sleep and critical illness: bridging the two pillars at the ATS 2016. J Thorac Dis. 2016 Jul; 8(Suppl 7):S536-8. PMID: 27606086; PMCID: PMC4990683.
      18. McCarra MB, Owens R. Obstructive sleep apnea: can the downward spiral be reversed-a summary of John Stradling's ATS keynote speech. J Thorac Dis. 2016 Jul; 8(Suppl 7):S539-41. PMID: 27606087; PMCID: PMC4990690.
      19. Li Y, Deacon N, Jen R, Owens R. Non positive airway pressure therapies for sleep disordered breathing from the ATS 2016. J Thorac Dis. 2016 Jul; 8(Suppl 7):S547-9. PMID: 27606090; PMCID: PMC4990676.
      20. Hepokoski M, Owens R, Malhotra A, Beitler JR. Mechanical ventilation in acute respiratory distress syndrome at ATS 2016: the search for a patient-specific strategy. J Thorac Dis. 2016 Jul; 8(Suppl 7):S550-2. PMID: 27606091; PMCID: PMC4990680.
      21. Beitler JR, Sands SA, Loring SH, Owens R, Malhotra A, Spragg RG, Matthay MA, Thompson BT, Talmor D. Quantifying unintended exposure to high tidal volumes from breath stacking dyssynchrony in ARDS: the BREATHE criteria. Intensive Care Med. 2016 Sep; 42(9):1427-36. PMID: 27342819; PMCID: PMC4992404 [Available on 09/01/17].
      22. Beitler JR, Owens R, Malhotra A. Unmasking a Role for Noninvasive Ventilation in Early Acute Respiratory Distress Syndrome. JAMA. 2016 Jun 14; 315(22):2401-3. PMID: 27179463.
        View in: PubMed
      23. Jen R, Li Y, Owens R, Malhotra A. Sleep in Chronic Obstructive Pulmonary Disease: Evidence Gaps and Challenges. Can Respir J. 2016; 2016:7947198. PMID: 27445564; PMCID: PMC4916278.
      24. Sands SA, Owens R, Malhotra A. New Approaches to Diagnosing Sleep-Disordered Breathing. Sleep Med Clin. 2016 Jun; 11(2):143-52. PMID: 27236052.
        View in: PubMed
      25. Sands SA, Owens R. Congestive Heart Failure and Central Sleep Apnea. Sleep Med Clin. 2016 Mar; 11(1):127-42. PMID: 26972039.
        View in: PubMed
      26. Genta PR, Edwards BA, Sands SA, Owens R, Butler JP, Loring SH, White DP, Wellman A. Tube Law of the Pharyngeal Airway in Sleeping Patients with Obstructive Sleep Apnea. Sleep. 2016 Feb 01; 39(2):337-43. PMID: 26446124; PMCID: PMC4712389.
      27. Beitler JR, Majumdar R, Hubmayr RD, Malhotra A, Thompson BT, Owens R, Loring SH, Talmor D. Volume Delivered During Recruitment Maneuver Predicts Lung Stress in Acute Respiratory Distress Syndrome. Crit Care Med. 2016 Jan; 44(1):91-9. PMID: 26474111.
        View in: PubMed
      28. Orr JE, Auger WR, DeYoung PN, Kim NH, Malhotra A, Owens R. Usefulness of Low Cardiac Index to Predict Sleep-Disordered Breathing in Chronic Thromboembolic Pulmonary Hypertension. Am J Cardiol. 2016 Mar 15; 117(6):1001-5. PMID: 26805659; PMCID: PMC4775368 [Available on 03/15/17].
      29. Balachandran JS, Wang T, Ko PR, Billings ME, Chow M, Panossian LA, Orr JE, Owens R, Kassutto SM, Sunwoo BY, Moussa A, Edinger JD, Uppalapati SV, Drake CL, Schmitt M, Weir I, Pien GW. ATS Core Curriculum 2015: Part II. Adult Sleep Medicine. Ann Am Thorac Soc. 2015 Oct; 12(10):1542-50. PMID: 26448351.
        View in: PubMed
      30. Ayas NT, Owens R, Kheirandish-Gozal L. Update in Sleep Medicine 2014. Am J Respir Crit Care Med. 2015 Aug 15; 192(4):415-20. PMID: 26278795.
        View in: PubMed
      31. Sands SA, Owens R. Congestive heart failure and central sleep apnea. Crit Care Clin. 2015 Jul; 31(3):473-95. PMID: 26118916; PMCID: PMC4486008.
      32. Owens R, Edwards BA, Eckert DJ, Jordan AS, Sands SA, Malhotra A, White DP, Loring SH, Butler JP, Wellman A. An Integrative Model of Physiological Traits Can be Used to Predict Obstructive Sleep Apnea and Response to Non Positive Airway Pressure Therapy. Sleep. 2015 Jun 01; 38(6):961-70. PMID: 25515107; PMCID: PMC4434563.
      33. Smales ET, Edwards BA, Deyoung PN, McSharry DG, Wellman A, Velasquez A, Owens R, Orr JE, Malhotra A. Trazodone Effects on Obstructive Sleep Apnea and Non-REM Arousal Threshold. Ann Am Thorac Soc. 2015 May; 12(5):758-64. PMID: 25719754; PMCID: PMC4418332.
      34. Malhotra A, Orr JE, Owens R. On the cutting edge of obstructive sleep apnoea: where next? Lancet Respir Med. 2015 May; 3(5):397-403. PMID: 25887980; PMCID: PMC4431916.
      35. Owens R, Shafazand S. Effects of CPAP and weight loss on OSA outcomes. J Clin Sleep Med. 2014 Dec 15; 10(12):1365-7. PMID: 25405486; PMCID: PMC4237535.
      36. Edwards BA, Eckert DJ, McSharry DG, Sands SA, Desai A, Kehlmann G, Bakker JP, Genta PR, Owens R, White DP, Wellman A, Malhotra A. Clinical predictors of the respiratory arousal threshold in patients with obstructive sleep apnea. Am J Respir Crit Care Med. 2014 Dec 01; 190(11):1293-300. PMID: 25321848; PMCID: PMC4315811.
      37. Wellman A, Genta PR, Owens R, Edwards BA, Sands SA, Loring SH, White DP, Jackson AC, Pedersen OF, Butler JP. Test of the Starling resistor model in the human upper airway during sleep. J Appl Physiol (1985). 2014 Dec 15; 117(12):1478-85. PMID: 25324514; PMCID: PMC4269684.
      38. Terrill PI, Edwards BA, Nemati S, Butler JP, Owens R, Eckert DJ, White DP, Malhotra A, Wellman A, Sands SA. Quantifying the ventilatory control contribution to sleep apnoea using polysomnography. Eur Respir J. 2015 Feb; 45(2):408-18. PMID: 25323235; PMCID: PMC4348093.
      39. Owens R. A big problem in the ICU. Initiation of CPAP/bilevel PAP therapy. J Clin Sleep Med. 2014 Oct 15; 10(10):1161-2. PMID: 25317100; PMCID: PMC4173097.
      40. Sands SA, Eckert DJ, Jordan AS, Edwards BA, Owens R, Butler JP, Schwab RJ, Loring SH, Malhotra A, White DP, Wellman A. Enhanced upper-airway muscle responsiveness is a distinct feature of overweight/obese individuals without sleep apnea. Am J Respir Crit Care Med. 2014 Oct 15; 190(8):930-7. PMID: 25191791; PMCID: PMC4299579.
      41. Dudley KA, Malhotra A, Owens R. Pulmonary Overlap Syndromes, with a focus on COPD and ILD. Sleep Med Clin. 2014 Sep; 9(3):365-379. PMID: 26664352.
        View in: PubMed
      42. Neilan TG, Bakker JP, Sharma B, Owens R, Farhad H, Shah RV, Abbasi SA, Kohli P, Wilson J, DeMaria A, Jerosch-Herold M, Kwong RY, Malhotra A. T1 measurements for detection of expansion of the myocardial extracellular volume in chronic obstructive pulmonary disease. Can J Cardiol. 2014 Dec; 30(12):1668-75. PMID: 25442461; PMCID: PMC4258158.
      43. Gillis CM, Poyant JO, Degrado JR, Ye L, Anger KE, Owens R. Inpatient pharmacological sleep aid utilization is common at a tertiary medical center. J Hosp Med. 2014 Oct; 9(10):652-7. PMID: 25130534.
        View in: PubMed
      44. Edwards BA, Sands SA, Owens R, White DP, Genta PR, Butler JP, Malhotra A, Wellman A. Effects of hyperoxia and hypoxia on the physiological traits responsible for obstructive sleep apnoea. J Physiol. 2014 Oct 15; 592(20):4523-35. PMID: 25085887; PMCID: PMC4287742.
      45. Genta PR, Owens R, Edwards BA, Sands SA, Eckert DJ, Butler JP, Loring SH, Malhotra A, Jackson AC, White DP, Wellman A. Influence of pharyngeal muscle activity on inspiratory negative effort dependence in the human upper airway. Respir Physiol Neurobiol. 2014 Sep 15; 201:55-9. PMID: 25020212; PMCID: PMC4131868.
      46. Edwards BA, Wellman A, Sands SA, Owens R, Eckert DJ, White DP, Malhotra A. Obstructive sleep apnea in older adults is a distinctly different physiological phenotype. Sleep. 2014 Jul 01; 37(7):1227-36. PMID: 25061251; PMCID: PMC4098808.
      47. Lamas DJ, Owens R, Bernacki RE, Block SD. Palliative care: a core competency for intensive care unit doctors. Am J Respir Crit Care Med. 2014 Jun 15; 189(12):1569. PMID: 24930536.
        View in: PubMed
      48. Owens R, Edwards BA, Sands SA, Butler JP, Eckert DJ, White DP, Malhotra A, Wellman A. The classical Starling resistor model often does not predict inspiratory airflow patterns in the human upper airway. J Appl Physiol (1985). 2014 Apr 15; 116(8):1105-12. PMID: 24458746; PMCID: PMC4035785.
      49. Sands SA, Owens R. Does my bed partner have OSA? There's an app for that! J Clin Sleep Med. 2014 Jan 15; 10(1):79-80. PMID: 24426824; PMCID: PMC3869074.
      50. Edwards BA, Wellman A, Owens R. PSGs: more than just the AHI. J Clin Sleep Med. 2013 Jun 15; 9(6):527-8. PMID: 23772183; PMCID: PMC3659370.
      51. Butler JP, Owens R, Malhotra A, Wellman A. CrossTalk opposing view: the human upper airway during sleep does not behave like a Starling resistor. J Physiol. 2013 May 01; 591(9):2233-4. PMID: 23740880; PMCID: PMC3650686.
      52. Butler JP, Owens R, Malhotra A, Wellman A. Rebuttal from James P. Butler, Robert L. Owens, Atul Malhotra and Andrew Wellman. J Physiol. 2013 May 01; 591(9):2237. PMID: 23740882; PMCID: PMC3650688.
      53. Campana LM, Owens R, Butler JP, Suki B, Malhotra A. Variability of respiratory mechanics during sleep in overweight and obese subjects with and without asthma. Respir Physiol Neurobiol. 2013 May 01; 186(3):290-5. PMID: 23473922; PMCID: PMC3659817.
      54. Wellman A, Edwards BA, Sands SA, Owens R, Nemati S, Butler J, Passaglia CL, Jackson AC, Malhotra A, White DP. A simplified method for determining phenotypic traits in patients with obstructive sleep apnea. J Appl Physiol (1985). 2013 Apr; 114(7):911-22. PMID: 23349453; PMCID: PMC3633440.
      55. Campana LM, Malhotra A, Suki B, Hess L, Israel E, Smales E, Deyoung P, Owens R. The effect of lung stretch during sleep on airway mechanics in overweight and obese asthma. Respir Physiol Neurobiol. 2013 Jan 15; 185(2):304-12. PMID: 23041446; PMCID: PMC3529972.
      56. Owens R, Edwards BA, Sands SA, Butler JP, Eckert DJ, White DP, Malhotra A, Wellman A. Upper airway collapsibility and patterns of flow limitation at constant end-expiratory lung volume. J Appl Physiol (1985). 2012 Sep 01; 113(5):691-9. PMID: 22628372; PMCID: PMC3472473.
      57. Owens R, Campana LM, Hess L, Eckert DJ, Loring SH, Malhotra A. Sitting and supine esophageal pressures in overweight and obese subjects. Obesity (Silver Spring). 2012 Dec; 20(12):2354-60. PMID: 22695479; PMCID: PMC3443522.
      58. Owens R, Edwards BA, Malhotra A, Wellman A. Expiratory resistance increases end-expiratory lung volume during sleep. Am J Respir Crit Care Med. 2012 Apr 15; 185(8):e10-1. PMID: 22505761; PMCID: PMC3360575.
      59. Edwards BA, Sands SA, Eckert DJ, White DP, Butler JP, Owens R, Malhotra A, Wellman A. Acetazolamide improves loop gain but not the other physiological traits causing obstructive sleep apnoea. J Physiol. 2012 Mar 01; 590(5):1199-211. PMID: 22219335; PMCID: PMC3381825.
      60. Campana LM, Owens R, Suki B, Malhotra A. Measuring upper and lower airway resistance during sleep with the forced oscillation technique. Ann Biomed Eng. 2012 Apr; 40(4):925-33. PMID: 22127514; PMCID: PMC3387574.
      61. Rémi J, Pfefferkorn T, Owens R, Schankin C, Dehning S, Birnbaum T, Bender A, Klein M, Adamec J, Pfister HW, Straube A, Feddersen B. The crossed leg sign indicates a favorable outcome after severe stroke. Neurology. 2011 Oct 11; 77(15):1453-6. PMID: 21987641; PMCID: PMC3198984.
      62. Eckert DJ, Owens R, Kehlmann GB, Wellman A, Rahangdale S, Yim-Yeh S, White DP, Malhotra A. Eszopiclone increases the respiratory arousal threshold and lowers the apnoea/hypopnoea index in obstructive sleep apnoea patients with a low arousal threshold. Clin Sci (Lond). 2011 Jun; 120(12):505-14. PMID: 21269278; PMCID: PMC3415379.
      63. Wellman A, Eckert DJ, Jordan AS, Edwards BA, Passaglia CL, Jackson AC, Gautam S, Owens R, Malhotra A, White DP. A method for measuring and modeling the physiological traits causing obstructive sleep apnea. J Appl Physiol (1985). 2011 Jun; 110(6):1627-37. PMID: 21436459; PMCID: PMC3119134.
      64. Owens R, Wellman A, Malhotra A. Which OSA Patients Might Respond to Nasal Valves? J Clin Sleep Med. 2011 Feb 15; 7(1):23-4. PMID: 21344055; PMCID: PMC3041631.
      65. Sharma B, Feinsilver S, Owens R, Malhotra A, McSharry D, Karbowitz S. Obstructive airway disease and obstructive sleep apnea: effect of pulmonary function. Lung. 2011 Feb; 189(1):37-41. PMID: 21132554; PMCID: PMC3417329.
      66. Owens R, Malhotra A. Sleep-disordered breathing and COPD: the overlap syndrome. Respir Care. 2010 Oct; 55(10):1333-44; discussion 1344-6. PMID: 20875160; PMCID: PMC3387564.
      67. Malhotra A, Owens R. What is central sleep apnea? Respir Care. 2010 Sep; 55(9):1168-78. PMID: 20799999; PMCID: PMC3417331.
      68. Gladysheva ES, Malhotra A, Owens R. Influencing the decline of lung function in COPD: use of pharmacotherapy. Int J Chron Obstruct Pulmon Dis. 2010 Jun 03; 5:153-64. PMID: 20631815; PMCID: PMC2898088.
      69. Jordan AS, White DP, Owens R, Eckert DJ, Rahangdale S, Yim-Yeh S, Malhotra A. The effect of increased genioglossus activity and end-expiratory lung volume on pharyngeal collapse. J Appl Physiol (1985). 2010 Aug; 109(2):469-75. PMID: 20507968; PMCID: PMC2928593.
      70. Sharma B, Owens R, Malhotra A. Sleep in congestive heart failure. Med Clin North Am. 2010 May; 94(3):447-64. PMID: 20451026; PMCID: PMC3424608.
      71. Campana LM, Owens R, Clifford GD, Pittman SD, Malhotra A. Phase-rectified signal averaging as a sensitive index of autonomic changes with aging. J Appl Physiol (1985). 2010 Jun; 108(6):1668-73. PMID: 20339014; PMCID: PMC2886688.
      72. Owens R, Malhotra A, Eckert DJ, White DP, Jordan AS. The influence of end-expiratory lung volume on measurements of pharyngeal collapsibility. J Appl Physiol (1985). 2010 Feb; 108(2):445-51. PMID: 19940097; PMCID: PMC3774250.
      73. Owens R, Harris RS, Malhotra A. Is the way to man's heart (and lung) through the abdomen? Crit Care. 2009; 13(6):199. PMID: 19909491; PMCID: PMC2811916.
      74. Owens R, Wellman A, Malhotra A. The chicken-or-egg debate in OSA pathogenesis. Sleep. 2009 Oct; 32(10):1255-6. PMID: 19848354; PMCID: PMC2753803.
      75. Owens R, Yim-Yeh S, Malhotra A. Carbon monoxide poisoning, or carbon monoxide protection? Chest. 2008 Nov; 134(5):895-896. PMID: 18988771; PMCID: PMC3888884.
      76. Owens R, Eckert DJ, Yeh SY, Malhotra A. Upper airway function in the pathogenesis of obstructive sleep apnea: a review of the current literature. Curr Opin Pulm Med. 2008 Nov; 14(6):519-24. PMID: 18812828; PMCID: PMC2697390.
      77. Owens R, Hess DR, Malhotra A, Venegas JG, Harris RS. Effect of the chest wall on pressure-volume curve analysis of acute respiratory distress syndrome lungs. Crit Care Med. 2008 Nov; 36(11):2980-5. PMID: 18824918.
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      78. Owens R, Stigler WS, Hess DR. Do newer monitors of exhaled gases, mechanics, and esophageal pressure add value? Clin Chest Med. 2008 Jun; 29(2):297-312, vi-vii. PMID: 18440438.
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